Compounds > docetaxel anhydrous
Page last updated: 2024-09-04

docetaxel anhydrous and vx680

docetaxel anhydrous has been researched along with vx680 in 3 studies

Compound Research Comparison

Studies
(docetaxel anhydrous)		Trials
(docetaxel anhydrous)		Recent Studies (post-2010)
(docetaxel anhydrous)		Studies
(vx680)		Trials
(vx680)		Recent Studies (post-2010) (vx680)
12,1103,2166,9202273143

Protein Interaction Comparison

ProteinTaxonomydocetaxel anhydrous (IC50)vx680 (IC50)
Aurora kinase AHomo sapiens (human)0.1805
Tyrosine-protein kinase ABL1Homo sapiens (human)0.4538
Tyrosine-protein kinase ABL1Mus musculus (house mouse)5
Proto-oncogene tyrosine-protein kinase SrcGallus gallus (chicken)0.34
Cyclin-dependent kinase 1Homo sapiens (human)0.4432
Insulin-like growth factor 1 receptorHomo sapiens (human)0.5
Beta-1 adrenergic receptorHomo sapiens (human)0.055
Breakpoint cluster region proteinHomo sapiens (human)0.0501
Cyclin-dependent kinase 4Homo sapiens (human)0.0006
G2/mitotic-specific cyclin-B1Homo sapiens (human)0.0092
G1/S-specific cyclin-D1Homo sapiens (human)0.0006
Cyclin-dependent kinase 2Homo sapiens (human)0.4974
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)0.03
Serine/threonine-protein kinase PLK1Homo sapiens (human)0.4974
Aurora kinase AMus musculus (house mouse)0.0006
Receptor-interacting serine/threonine-protein kinase 1Homo sapiens (human)0.208
Maternal embryonic leucine zipper kinaseHomo sapiens (human)0.42
Discoidin domain-containing receptor 2Homo sapiens (human)0.1295
Receptor-interacting serine/threonine-protein kinase 1 Mus musculus (house mouse)1
Aurora kinase B-AXenopus laevis (African clawed frog)0.019
Aurora kinase BHomo sapiens (human)0.2175
Serine/threonine-protein kinase TBK1Homo sapiens (human)3.1131
Aurora kinase CHomo sapiens (human)0.3516

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (33.33)29.6817
2010's2 (66.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Armaiz-Pena, GN; Bodurka, DC; Brinkley, WR; Coleman, RL; Gray, MJ; Han, LY; Immaneni, A; Kamat, AA; Kim, SW; Landen, CN; Lin, YG; Lu, C; Mangala, LS; Merritt, WM; Nick, AM; Shahzad, MM; Sood, AK; Spannuth, WA; Tsang, YT; Wong, KK1
Jeet, V; Khatri, A; Russell, PJ; Verma, ND1

Other Studies

3 other study(ies) available for docetaxel anhydrous and vx680

ArticleYear
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
Targeting aurora kinase with MK-0457 inhibits ovarian cancer growth.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2008, Sep-01, Volume: 14, Issue:17

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Aurora Kinases; Cell Line, Tumor; Cell Proliferation; Cell Survival; Docetaxel; Enzyme Inhibitors; Female; Humans; Mice; Ovarian Neoplasms; Piperazines; Protein Serine-Threonine Kinases; Taxoids; Xenograft Model Antitumor Assays

2008
Targeting aurora kinases: a novel approach to curb the growth & chemoresistance of androgen refractory prostate cancer.
    Current cancer drug targets, 2012, Volume: 12, Issue:2

    Topics: Androgens; Animals; Aurora Kinases; Docetaxel; Drug Resistance, Neoplasm; Drug Synergism; Gene Expression Profiling; Male; Mice; Mice, Transgenic; Neoplasm Metastasis; Piperazines; Prostatic Neoplasms; Protein Kinase Inhibitors; Protein Serine-Threonine Kinases; Real-Time Polymerase Chain Reaction; RNA Interference; Taxoids

2012