docetaxel anhydrous has been researched along with simvastatin in 10 studies
| Studies (docetaxel anhydrous) | Trials (docetaxel anhydrous) | Recent Studies (post-2010) (docetaxel anhydrous) | Studies (simvastatin) | Trials (simvastatin) | Recent Studies (post-2010) (simvastatin) |
|---|---|---|---|---|---|
| 12,110 | 3,216 | 6,920 | 8,442 | 1,730 | 3,630 |
| Protein | Taxonomy | docetaxel anhydrous (IC50) | simvastatin (IC50) |
|---|---|---|---|
| photoreceptor-specific nuclear receptor | Homo sapiens (human) | 1.164 | |
| transactivating tegument protein VP16 [Human herpesvirus 1] | Human alphaherpesvirus 1 (Herpes simplex virus type 1) | 4.426 | |
| Bile salt export pump | Homo sapiens (human) | 10 | |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Homo sapiens (human) | 0.7843 | |
| ATP-dependent translocase ABCB1 | Homo sapiens (human) | 9.5 | |
| Insulin receptor | Rattus norvegicus (Norway rat) | 0.0034 | |
| Prostaglandin G/H synthase 2 | Homo sapiens (human) | 0.0034 | |
| 3-hydroxy-3-methylglutaryl-coenzyme A reductase | Rattus norvegicus (Norway rat) | 0.0111 | |
| Sigma non-opioid intracellular receptor 1 | Cavia porcellus (domestic guinea pig) | 0.049 | |
| Solute carrier organic anion transporter family member 1B1 | Homo sapiens (human) | 6.7 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 8 (80.00) | 24.3611 |
| 2020's | 2 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Talele, TT | 1 |
| Al-Azayzih, A; Al-Husein, B; Goc, A; Kochuparambil, ST; Mohammad, S; Somanath, PR | 1 |
| Aigner, A; Boehm, A; Dietz, A; Mozet, C; Stoehr, M; Wichmann, G | 1 |
| Batra, SK; Chen, HT; Hsieh, KC; Ingersoll, MA; Kao, CL; Lin, MF; Martinez, O; Miller, DR; Simha, MV; Wakefield, CB | 1 |
| Chung, KH; Jung, EJ; Kim, CW | 1 |
| Bruzzese, F; Budillon, A; Ciardiello, C; Ciliberto, G; Costantini, S; De Rienzo, S; Di Gennaro, E; Grumetti, L; Iannelli, F; Leone, A; Lombardi, R; Mancini, R; Milone, MR; Moccia, T; Pucci, B; Roca, MS; Sorice, A; Vitagliano, C | 1 |
| Crown, J; Duffy, MJ; O'Grady, S | 1 |
2 review(s) available for docetaxel anhydrous and simvastatin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Natural-Products-Inspired Use of the gem-Dimethyl Group in Medicinal Chemistry.
Topics: Animals; Biological Products; Chemistry, Pharmaceutical; Humans | 2018 |
8 other study(ies) available for docetaxel anhydrous and simvastatin
| Article | Year |
|---|---|
Identification of potent Yes1 kinase inhibitors using a library screening approach.
Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship | 2013 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Simultaneous modulation of the intrinsic and extrinsic pathways by simvastatin in mediating prostate cancer cell apoptosis.
Topics: Animals; Antineoplastic Agents; Apoptosis; bcl-Associated Death Protein; bcl-X Protein; Caspase 3; Caspase 9; Cell Line, Tumor; Cell Survival; Docetaxel; Fas Ligand Protein; Humans; Male; Mice; Mice, Nude; Phosphorylation; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Receptors, Death Domain; Signal Transduction; Simvastatin; Taxoids | 2012 |
Simvastatin suppresses head and neck squamous cell carcinoma ex vivo and enhances the cytostatic effects of chemotherapeutics.
Topics: Anticholesteremic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cell Line, Tumor; Cisplatin; Docetaxel; Dose-Response Relationship, Drug; Drug Synergism; Female; Head and Neck Neoplasms; Humans; KB Cells; Male; Neoplasm Staging; Risk Factors; Simvastatin; Squamous Cell Carcinoma of Head and Neck; Taxoids | 2014 |
Statin derivatives as therapeutic agents for castration-resistant prostate cancer.
Topics: Androgen Antagonists; Antineoplastic Agents, Hormonal; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Cholesterol; Docetaxel; Dose-Response Relationship, Drug; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Male; Neoplasm Invasiveness; Prostatic Neoplasms, Castration-Resistant; Proto-Oncogene Proteins c-akt; Receptors, Androgen; S Phase Cell Cycle Checkpoints; Signal Transduction; Simvastatin; Taxoids | 2016 |
Identification of simvastatin-regulated targets associated with JNK activation in DU145 human prostate cancer cell death signaling.
Topics: Anthracenes; Apoptosis; Cell Line, Tumor; Docetaxel; Gene Expression Regulation, Neoplastic; Heterogeneous-Nuclear Ribonucleoprotein K; Humans; JNK Mitogen-Activated Protein Kinases; Male; Phosphorylation; Prostatic Neoplasms; Proteomics; Signal Transduction; Simvastatin; Taxoids | 2017 |
Synergistic antitumor interaction of valproic acid and simvastatin sensitizes prostate cancer to docetaxel by targeting CSCs compartment via YAP inhibition.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor; Cell Cycle Proteins; Cell Movement; Cell Proliferation; Docetaxel; Drug Resistance, Neoplasm; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Male; Mice; Mice, Inbred NOD; Mice, SCID; Neoplastic Stem Cells; Prostatic Neoplasms; Simvastatin; Transcription Factors; Tumor Cells, Cultured; Valproic Acid; Xenograft Model Antitumor Assays | 2020 |
Statins inhibit proliferation and induce apoptosis in triple-negative breast cancer cells.
Topics: Apoptosis; Cell Line, Tumor; Cell Proliferation; Docetaxel; Doxorubicin; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Simvastatin; Triple Negative Breast Neoplasms; Tumor Suppressor Protein p53 | 2022 |