Compounds > docetaxel anhydrous
Page last updated: 2024-09-04

docetaxel anhydrous and rucaparib

docetaxel anhydrous has been researched along with rucaparib in 3 studies

Compound Research Comparison

Studies
(docetaxel anhydrous)		Trials
(docetaxel anhydrous)		Recent Studies (post-2010)
(docetaxel anhydrous)		Studies
(rucaparib)		Trials
(rucaparib)		Recent Studies (post-2010) (rucaparib)
12,1103,2166,92023636220

Protein Interaction Comparison

ProteinTaxonomydocetaxel anhydrous (IC50)rucaparib (IC50)
Poly [ADP-ribose] polymerase tankyrase-1Homo sapiens (human)0.0847
Poly [ADP-ribose] polymerase 1Homo sapiens (human)0.0418
Protein mono-ADP-ribosyltransferase PARP14Homo sapiens (human)8.8713
Protein mono-ADP-ribosyltransferase PARP10Homo sapiens (human)1.4333
Protein mono-ADP-ribosyltransferase PARP12Homo sapiens (human)6.6285
Poly [ADP-ribose] polymerase tankyrase-2Homo sapiens (human)0.4523
Poly [ADP-ribose] polymerase 2Homo sapiens (human)0.0497
Protein mono-ADP-ribosyltransferase PARP4Homo sapiens (human)0.8354
Protein mono-ADP-ribosyltransferase PARP3Homo sapiens (human)0.4597

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (66.67)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Cai, C; Duan, X; Kong, Z; Lai, Y; Li, S; Wu, W; Xu, S; Zeng, T; Zhao, Z1
Abida, W; Bambury, RM; Bryce, AH; Chowdhury, S; Daugaard, G; Despain, D; Emmenegger, U; Fizazi, K; Gingerich, JR; Heidenreich, A; Heyes, CA; Krieger, L; Lindberg, H; Loehr, A; McDermott, R; Morris, D; Nolè, F; Ostler, P; Pintus, E; Piulats, JM; Reaume, MN; Redfern, C; Ryan, CJ; Sáez, MI; Sautois, B; Sridhar, SS; Staffurth, J; Watkins, SP1

Trials

1 trial(s) available for docetaxel anhydrous and rucaparib

ArticleYear
Rucaparib or Physician's Choice in Metastatic Prostate Cancer.
    The New England journal of medicine, 2023, 02-23, Volume: 388, Issue:8

    Topics: Androgen Antagonists; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Disease Progression; Docetaxel; Genes, BRCA1; Genes, BRCA2; Humans; Indoles; Male; Poly(ADP-ribose) Polymerase Inhibitors; Progression-Free Survival; Prostatic Neoplasms, Castration-Resistant

2023

Other Studies

2 other study(ies) available for docetaxel anhydrous and rucaparib

ArticleYear
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
PARP1-siRNA suppresses human prostate cancer cell growth and progression.
    Oncology reports, 2018, Volume: 39, Issue:4

    Topics: Animals; Apoptosis; Cell Line, Tumor; Cell Movement; Cell Proliferation; Disease Progression; Docetaxel; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Indoles; Male; Mice; Phthalazines; Piperazines; Poly (ADP-Ribose) Polymerase-1; Poly(ADP-ribose) Polymerase Inhibitors; Prostatic Neoplasms; RNA, Small Interfering; Taxoids; Xenograft Model Antitumor Assays

2018