Page last updated: 2024-09-04

docetaxel anhydrous and raltitrexed

docetaxel anhydrous has been researched along with raltitrexed in 7 studies

Compound Research Comparison

Studies
(docetaxel anhydrous)
Trials
(docetaxel anhydrous)
Recent Studies (post-2010)
(docetaxel anhydrous)
Studies
(raltitrexed)
Trials
(raltitrexed)
Recent Studies (post-2010) (raltitrexed)
12,1103,2166,920580143121

Protein Interaction Comparison

ProteinTaxonomydocetaxel anhydrous (IC50)raltitrexed (IC50)
Thymidylate synthase Escherichia coli7.0667
Dihydrofolate reductaseHomo sapiens (human)1.8578
Thymidylate synthaseLacticaseibacillus casei8.2667
Thymidylate synthaseHomo sapiens (human)1.208
Thymidylate synthaseMus musculus (house mouse)0.67
Thymidylate synthaseEscherichia coli K-122.32
Dihydrofolate reductaseEscherichia coli K-122.32
Folate receptor betaHomo sapiens (human)0.384
Folate receptor alphaHomo sapiens (human)0.015
Non-receptor tyrosine-protein kinase TYK2Homo sapiens (human)0.26
Reduced folate transporterHomo sapiens (human)0.0063
Thymidylate synthase Rattus norvegicus (Norway rat)0.9
Bifunctional dihydrofolate reductase-thymidylate synthaseToxoplasma gondii1.7956
Proton-coupled folate transporterHomo sapiens (human)0.0995

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (42.86)18.2507
2000's2 (28.57)29.6817
2010's1 (14.29)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Ogawa, M1
Armand, JP; Cunningham, D; Kohne, CH; Misset, JL; van Cutsem, E1
Adenis, A; Conroy, T; Paillot, B1
Bianco, AR; Bianco, R; Caputo, R; Ciardiello, F; Damiano, V; De Placido, S; Pomatico, G; Tortora, G1
Berg, R; Koropatnick, J; Pandyra, AA; Vincent, M1
Cai, B; Di, X; Ge, X; Liu, Z; Sun, X; Xia, X1

Reviews

3 review(s) available for docetaxel anhydrous and raltitrexed

ArticleYear
New systemic drugs in the treatment of gastrointestinal cancer.
    Current opinion in oncology, 1996, Volume: 8, Issue:4

    Topics: Antineoplastic Agents, Phytogenic; Camptothecin; Clinical Trials as Topic; Docetaxel; Gastrointestinal Neoplasms; Humans; Irinotecan; Paclitaxel; Quinazolines; Taxoids; Thiophenes; Thymidylate Synthase

1996
Clinical advances with topoisomerase I inhibitors in gastrointestinal malignancies.
    Anti-cancer drugs, 1999, Volume: 10 Suppl 1

    Topics: Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Docetaxel; Enzyme Inhibitors; Fluorouracil; Gastrointestinal Neoplasms; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Platinum; Quinazolines; Taxoids; Thiophenes; Topoisomerase I Inhibitors

1999
[New drugs in gastrointestinal oncology. Current status and future directions].
    Gastroenterologie clinique et biologique, 1999, Volume: 23, Issue:11

    Topics: Antineoplastic Agents; Camptothecin; Capecitabine; Deoxycytidine; Docetaxel; Floxuridine; Fluorouracil; Gastrointestinal Neoplasms; Gemcitabine; Humans; Irinotecan; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Quinazolines; Taxoids; Tegafur; Thiophenes; Vinblastine; Vinorelbine

1999

Other Studies

4 other study(ies) available for docetaxel anhydrous and raltitrexed

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Antitumor effect and potentiation of cytotoxic drugs activity in human cancer cells by ZD-1839 (Iressa), an epidermal growth factor receptor-selective tyrosine kinase inhibitor.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2000, Volume: 6, Issue:5

    Topics: Animals; Antineoplastic Agents; Apoptosis; Carboplatin; Cell Division; Cisplatin; Docetaxel; Dose-Response Relationship, Drug; Drug Synergism; ErbB Receptors; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Neoplasms, Experimental; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Quinazolines; Survival Rate; Taxoids; Thiophenes; Topotecan; Transplantation, Heterologous; Tumor Cells, Cultured

2000
Combination silencer RNA (siRNA) targeting Bcl-2 antagonizes siRNA against thymidylate synthase in human tumor cell lines.
    The Journal of pharmacology and experimental therapeutics, 2007, Volume: 322, Issue:1

    Topics: Cell Line, Tumor; Cell Proliferation; Docetaxel; Floxuridine; G1 Phase; Humans; Neoplasms; Proto-Oncogene Proteins c-bcl-2; Quinazolines; RNA, Messenger; RNA, Small Interfering; Taxoids; Thiophenes; Thymidylate Synthase

2007
A comparison between raltitrexed plus cisplatin and docetaxel plus cisplatin in concurrent chemoradiation for non-surgical esophageal squamous cell carcinoma.
    Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique, 2021, Volume: 25, Issue:1

    Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Cisplatin; Docetaxel; Esophageal Neoplasms; Esophageal Squamous Cell Carcinoma; Female; Humans; Male; Middle Aged; Quinazolines; Radiotherapy, Intensity-Modulated; Regression Analysis; Retrospective Studies; Survival Rate; Thiophenes; Treatment Outcome

2021