Page last updated: 2024-09-04

docetaxel anhydrous and podophyllotoxin

docetaxel anhydrous has been researched along with podophyllotoxin in 7 studies

Compound Research Comparison

Studies
(docetaxel anhydrous)
Trials
(docetaxel anhydrous)
Recent Studies (post-2010)
(docetaxel anhydrous)
Studies
(podophyllotoxin)
Trials
(podophyllotoxin)
Recent Studies (post-2010) (podophyllotoxin)
12,1103,2166,9203,119226782

Protein Interaction Comparison

ProteinTaxonomydocetaxel anhydrous (IC50)podophyllotoxin (IC50)
nuclear receptor subfamily 0 group B member 1Homo sapiens (human)2.145
Tubulin alpha-1A chainSus scrofa (pig)0.6733
Tubulin beta chainSus scrofa (pig)0.622
Glucocorticoid receptorHomo sapiens (human)0.014
Tubulin beta-4A chainHomo sapiens (human)1.7233
Tubulin beta chainHomo sapiens (human)1.7233
Cytochrome P450 3A4Homo sapiens (human)0.6
Tubulin alpha-3C chainHomo sapiens (human)1.7233
Cytochrome P450 2C9 Homo sapiens (human)4
Cytochrome P450 2C19Homo sapiens (human)5
Tubulin alpha-1B chainHomo sapiens (human)1.7233
Tubulin alpha-4A chainHomo sapiens (human)1.7233
Tubulin beta-4B chainHomo sapiens (human)1.7233
Tubulin beta-3 chainHomo sapiens (human)1.7233
Tubulin beta-2A chainHomo sapiens (human)1.7233
Tubulin beta-8 chainHomo sapiens (human)1.7233
Calcium-activated potassium channel subunit alpha-1Rattus norvegicus (Norway rat)0.56
Tubulin beta-2B chainBos taurus (cattle)0.8685
Tubulin alpha-3E chainHomo sapiens (human)1.7233
Tubulin alpha-1A chainHomo sapiens (human)1.7233
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)0.907
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)0.7744
Tubulin alpha-1C chainHomo sapiens (human)1.7233
Tubulin beta-6 chainHomo sapiens (human)1.7233
Tubulin beta-2B chainHomo sapiens (human)1.7233
Tubulin beta-1 chainHomo sapiens (human)1.7233

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (28.57)29.6817
2010's5 (71.43)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Brett, ML; Colley, HE; Coole, SF; Danson, SJ; Dossetter, AG; Griffen, EJ; Harrison, J; Jackson, LV; Jennings, LR; Lockey, PM; Mason, DP; Muthana, M; Norman, D; Thompson, MJ; Tulasi, V; Williams, L; Wong, M1
Markman, M; Zanotti, KM1
Bunn, PA; Simon, GR1
Ahn, S; Dalton, JT; Li, CM; Lu, Y; Miller, DD; Narayanan, R1
Belaaloui, G; Jiang, ZZ; Khaled, M; Zhang, LY; Zhu, X1
Andor, G; Bergqvist, M; Bondarenko, I; Grechanaya, E; Harmenberg, J; Holgersson, G; Jerling, M; Klockare, M; Maximovich, A; Thureson, M1

Reviews

2 review(s) available for docetaxel anhydrous and podophyllotoxin

ArticleYear
Prevention and management of antineoplastic-induced hypersensitivity reactions.
    Drug safety, 2001, Volume: 24, Issue:10

    Topics: Antineoplastic Agents; Asparaginase; Docetaxel; Drug Hypersensitivity; Humans; Neoplasms; Organoplatinum Compounds; Paclitaxel; Podophyllotoxin; Taxoids

2001
Taxanes in the treatment of advanced (stage III and IV) non-small cell lung cancer (NSCLC): recent developments.
    Cancer investigation, 2003, Volume: 21, Issue:1

    Topics: Angiogenesis Inhibitors; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Clinical Trials as Topic; Combined Modality Therapy; Deoxycytidine; Docetaxel; Etoposide; Female; Gemcitabine; Humans; Lung Neoplasms; Male; Microtubules; Multicenter Studies as Topic; Neoadjuvant Therapy; Organoplatinum Compounds; Paclitaxel; Palliative Care; Podophyllotoxin; Randomized Controlled Trials as Topic; Salvage Therapy; Survival Analysis; Taxoids; Teniposide; Treatment Outcome; Vinblastine; Vinorelbine

2003

Trials

1 trial(s) available for docetaxel anhydrous and podophyllotoxin

ArticleYear
Phase II randomized study of the IGF-1R pathway modulator AXL1717 compared to docetaxel in patients with previously treated, locally advanced or metastatic non-small cell lung cancer.
    Acta oncologica (Stockholm, Sweden), 2017, Volume: 56, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Chemotherapy, Adjuvant; Disease Progression; Docetaxel; Female; Humans; Lung Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Podophyllotoxin; Receptor, IGF Type 1; Receptors, Somatomedin; Signal Transduction; Survival Analysis; Taxoids; Treatment Outcome

2017

Other Studies

4 other study(ies) available for docetaxel anhydrous and podophyllotoxin

ArticleYear
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
An Orally Bioavailable, Indole-3-glyoxylamide Based Series of Tubulin Polymerization Inhibitors Showing Tumor Growth Inhibition in a Mouse Xenograft Model of Head and Neck Cancer.
    Journal of medicinal chemistry, 2015, Dec-10, Volume: 58, Issue:23

    Topics: Animals; Antineoplastic Agents; Caco-2 Cells; Cell Proliferation; Drug Screening Assays, Antitumor; Head and Neck Neoplasms; Heterografts; Humans; Indoles; Male; Mice; Mice, Nude; Microtubules; Neoplasm Transplantation; Structure-Activity Relationship; Tubulin; Tubulin Modulators

2015
Competitive mass spectrometry binding assay for characterization of three binding sites of tubulin.
    Journal of mass spectrometry : JMS, 2010, Volume: 45, Issue:10

    Topics: Animals; Binding Sites; Binding, Competitive; Cattle; Chromatography, Liquid; Colchicine; Docetaxel; Guanosine Triphosphate; Linear Models; Paclitaxel; Podophyllotoxin; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Taxoids; Thiazoles; Tubulin; Tubulin Modulators; Vinblastine; Vincristine

2010
Antitumor effect of Deoxypodophyllotoxin on human breast cancer xenograft transplanted in BALB/c nude mice model.
    Journal of infection and chemotherapy : official journal of the Japan Society of Chemotherapy, 2016, Volume: 22, Issue:10

    Topics: 2-Hydroxypropyl-beta-cyclodextrin; Administration, Intravenous; Animals; Antineoplastic Agents, Phytogenic; beta-Cyclodextrins; Breast Neoplasms; Cell Line, Tumor; Docetaxel; Drugs, Chinese Herbal; Etoposide; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Podophyllotoxin; Taxoids; Xenograft Model Antitumor Assays

2016