Page last updated: 2024-09-04

docetaxel anhydrous and pf-477736

docetaxel anhydrous has been researched along with pf-477736 in 2 studies

Compound Research Comparison

Studies (docetaxel anhydrous)	Trials (docetaxel anhydrous)	Recent Studies (post-2010) (docetaxel anhydrous)	Studies (pf-477736)	Trials (pf-477736)	Recent Studies (post-2010) (pf-477736)
12,110	3,216	6,920	34	0	30

Protein Interaction Comparison

Protein	Taxonomy	pf-477736 (IC50)
Aurora kinase A	Homo sapiens (human)	0.023
Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)	0.01
Tyrosine-protein kinase Yes	Homo sapiens (human)	0.014
Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)	0.039
Fibroblast growth factor receptor 3	Homo sapiens (human)	0.023
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	0.008
Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)	0.025
LIM domain kinase 1	Homo sapiens (human)	0.4616
LIM domain kinase 2	Homo sapiens (human)	1.8319

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	1 (50.00)	29.6817
2010's	1 (50.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ	1
Anderes, K; Arango, ME; Buckman, D; Chen, E; Christensen, JG; Hallin, J; Hallin, M; Kuszpit, K; Painter, CL; Qiu, M; Sun, G; Wong, A; Yan, Z; Zasadny, K; Zhang, C; Zhang, Q	1

Other Studies

2 other study(ies) available for docetaxel anhydrous and pf-477736

Article	Year
Identification of potent Yes1 kinase inhibitors using a library screening approach. Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15 Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship	2013
PF-00477736 mediates checkpoint kinase 1 signaling pathway and potentiates docetaxel-induced efficacy in xenografts. Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Jul-15, Volume: 15, Issue:14 Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzodiazepinones; cdc25 Phosphatases; Cell Line, Tumor; Cell Survival; Checkpoint Kinase 1; Dideoxynucleosides; Docetaxel; Drug Synergism; Fluorine Radioisotopes; Histones; Humans; Mice; Mice, Nude; Neoplasms; Phosphorylation; Protein Kinases; Pyrazoles; Signal Transduction; Taxoids; Tomography, Emission-Computed; Tumor Burden; Xenograft Model Antitumor Assays	2009

Article

Year

Identification of potent Yes1 kinase inhibitors using a library screening approach.

Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013

PF-00477736 mediates checkpoint kinase 1 signaling pathway and potentiates docetaxel-induced efficacy in xenografts.

Clinical cancer research : an official journal of the American Association for Cancer Research, 2009, Jul-15, Volume: 15, Issue:14

Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzodiazepinones; cdc25 Phosphatases; Cell Line, Tumor; Cell Survival; Checkpoint Kinase 1; Dideoxynucleosides; Docetaxel; Drug Synergism; Fluorine Radioisotopes; Histones; Humans; Mice; Mice, Nude; Neoplasms; Phosphorylation; Protein Kinases; Pyrazoles; Signal Transduction; Taxoids; Tomography, Emission-Computed; Tumor Burden; Xenograft Model Antitumor Assays

2009