Page last updated: 2024-09-04

docetaxel anhydrous and pevonedistat

docetaxel anhydrous has been researched along with pevonedistat in 2 studies

Compound Research Comparison

Studies
(docetaxel anhydrous)
Trials
(docetaxel anhydrous)
Recent Studies (post-2010)
(docetaxel anhydrous)
Studies
(pevonedistat)
Trials
(pevonedistat)
Recent Studies (post-2010) (pevonedistat)
12,1103,2166,92029911289

Protein Interaction Comparison

ProteinTaxonomydocetaxel anhydrous (IC50)pevonedistat (IC50)
Ubiquitin-like modifier-activating enzyme 6Homo sapiens (human)1.8
Ubiquitin-like modifier-activating enzyme 1 Mus musculus (house mouse)1.5
NEDD8-activating enzyme E1 regulatory subunitHomo sapiens (human)0.0471
NEDD8Homo sapiens (human)0.0047
NEDD8-activating enzyme E1 catalytic subunitHomo sapiens (human)0.0033
SUMO-activating enzyme subunit 1Homo sapiens (human)8.2
SUMO-activating enzyme subunit 2Homo sapiens (human)8.2

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (50.00)24.3611
2020's1 (50.00)2.80

Authors

AuthorsStudies
Bauer, TM; Faessel, H; Faller, DV; Harvey, RD; Lockhart, AC; Nemunaitis, J; Sedarati, F; Venkatakrishnan, K; Zhou, X1
Bouchal, J; Gachechiladze, M; Kharaishvili, G; Kral, M; Kurfurstova, D; Mickova, A; Mistrik, M; Pokryvkova, B; Soucek, K; Vacek, O1

Trials

1 trial(s) available for docetaxel anhydrous and pevonedistat

ArticleYear
Effect of CYP3A inhibitors on the pharmacokinetics of pevonedistat in patients with advanced solid tumours.
    British journal of clinical pharmacology, 2019, Volume: 85, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Carboplatin; Cyclopentanes; Cytochrome P-450 CYP3A Inhibitors; Docetaxel; Drug Interactions; Enzyme Inhibitors; Female; Fluconazole; Humans; Itraconazole; Male; Middle Aged; Neoplasms; Paclitaxel; Pyrimidines

2019

Other Studies

1 other study(ies) available for docetaxel anhydrous and pevonedistat

ArticleYear
Skp2 and Slug Are Coexpressed in Aggressive Prostate Cancer and Inhibited by Neddylation Blockade.
    International journal of molecular sciences, 2021, Mar-11, Volume: 22, Issue:6

    Topics: Antigens, CD; Antineoplastic Agents; Cadherins; Cell Line, Tumor; Cell Survival; Cyclin-Dependent Kinase Inhibitor p27; Cyclopentanes; Docetaxel; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; Humans; Lymphatic Metastasis; Male; NEDD8 Protein; Neoplasm Grading; PC-3 Cells; Prostate; Prostatic Neoplasms; Protein Processing, Post-Translational; Pyrimidines; Receptors, Androgen; RNA, Small Interfering; S-Phase Kinase-Associated Proteins; Snail Family Transcription Factors

2021