Page last updated: 2024-09-04

docetaxel anhydrous and nutlin-3a

docetaxel anhydrous has been researched along with nutlin-3a in 2 studies

Compound Research Comparison

Studies (docetaxel anhydrous)	Trials (docetaxel anhydrous)	Recent Studies (post-2010) (docetaxel anhydrous)	Studies (nutlin-3a)	Trials (nutlin-3a)	Recent Studies (post-2010) (nutlin-3a)
12,110	3,216	6,920	698	1	504

Protein Interaction Comparison

Protein	Taxonomy	nutlin-3a (IC50)
Protein Mdm4	Homo sapiens (human)	4.6273
Cellular tumor antigen p53	Homo sapiens (human)	1.0388
Cytochrome P450 2C19	Homo sapiens (human)	0.07
E3 ubiquitin-protein ligase Mdm2	Homo sapiens (human)	0.1832

Research

Studies (2)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (100.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Bishop, WR; Bogen, SL; Doll, RJ; Gibeau, CR; Hicklin, DJ; Lahue, BR; Lin, Y; Lipari, P; Liu, M; Liu, S; Ma, Y; Mirza, A; Nair, LG; Nomeir, A; Pan, W; Prosise, W; Reichert, P; Rindgen, D; Scapin, G; Seidel-Dugan, C; Seigel, E; Shipps, GW; Strickland, C; Tian, Y; Wang, X; Wang, Y	1
Croft, A; Hersey, P; Jiang, CC; Liu, H; Tay, KH; Thorne, RF; Tseng, HY; Yang, F; Zhang, XD	1

Other Studies

2 other study(ies) available for docetaxel anhydrous and nutlin-3a

Article	Year
Discovery of Novel 3,3-Disubstituted Piperidines as Orally Bioavailable, Potent, and Efficacious HDM2-p53 Inhibitors. ACS medicinal chemistry letters, 2016, Mar-10, Volume: 7, Issue:3 Topics:	2016
Contrasting effects of nutlin-3 on TRAIL- and docetaxel-induced apoptosis due to upregulation of TRAIL-R2 and Mcl-1 in human melanoma cells. Molecular cancer therapeutics, 2010, Volume: 9, Issue:12 Topics: Apoptosis; Cell Line, Tumor; Cytoprotection; Docetaxel; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Melanoma; Myeloid Cell Leukemia Sequence 1 Protein; Piperazines; Protein Biosynthesis; Proto-Oncogene Proteins c-bcl-2; Receptors, TNF-Related Apoptosis-Inducing Ligand; Taxoids; TNF-Related Apoptosis-Inducing Ligand; Transcription, Genetic; Tumor Suppressor Protein p53; Up-Regulation	2010

Article

Year

Discovery of Novel 3,3-Disubstituted Piperidines as Orally Bioavailable, Potent, and Efficacious HDM2-p53 Inhibitors.

ACS medicinal chemistry letters, 2016, Mar-10, Volume: 7, Issue:3

Topics:

2016

Contrasting effects of nutlin-3 on TRAIL- and docetaxel-induced apoptosis due to upregulation of TRAIL-R2 and Mcl-1 in human melanoma cells.

Molecular cancer therapeutics, 2010, Volume: 9, Issue:12

Topics: Apoptosis; Cell Line, Tumor; Cytoprotection; Docetaxel; Gene Expression Regulation, Neoplastic; Humans; Imidazoles; Melanoma; Myeloid Cell Leukemia Sequence 1 Protein; Piperazines; Protein Biosynthesis; Proto-Oncogene Proteins c-bcl-2; Receptors, TNF-Related Apoptosis-Inducing Ligand; Taxoids; TNF-Related Apoptosis-Inducing Ligand; Transcription, Genetic; Tumor Suppressor Protein p53; Up-Regulation

2010