docetaxel anhydrous has been researched along with mifepristone in 4 studies
Studies (docetaxel anhydrous) | Trials (docetaxel anhydrous) | Recent Studies (post-2010) (docetaxel anhydrous) | Studies (mifepristone) | Trials (mifepristone) | Recent Studies (post-2010) (mifepristone) |
---|---|---|---|---|---|
12,110 | 3,216 | 6,920 | 6,536 | 595 | 1,758 |
Protein | Taxonomy | docetaxel anhydrous (IC50) | mifepristone (IC50) |
---|---|---|---|
Glucocorticoid receptor | Canis lupus familiaris (dog) | 0.0264 | |
Bile salt export pump | Homo sapiens (human) | 2.02 | |
Estrogen receptor | Homo sapiens (human) | 4.311 | |
Glucocorticoid receptor | Homo sapiens (human) | 0.0249 | |
Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 0.0003 | |
Progesterone receptor | Homo sapiens (human) | 0.1347 | |
Glucocorticoid receptor | Rattus norvegicus (Norway rat) | 0.774 | |
Glucocorticoid receptor | Mus musculus (house mouse) | 0.0022 | |
Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | 0.0022 | |
Mineralocorticoid receptor | Homo sapiens (human) | 2.0938 | |
Cytochrome P450 3A4 | Homo sapiens (human) | 9.5 | |
Coagulation factor VII | Homo sapiens (human) | 0.0003 | |
Androgen receptor | Homo sapiens (human) | 0.2988 | |
Cytochrome P450 2C8 | Homo sapiens (human) | 1.5 | |
Cytochrome P450 2C9 | Homo sapiens (human) | 4.9 | |
Steroid 17-alpha-hydroxylase/17,20 lyase | Rattus norvegicus (Norway rat) | 0.0016 | |
Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 0.555 | |
Tissue factor | Homo sapiens (human) | 0.0003 | |
Androgen receptor | Rattus norvegicus (Norway rat) | 0.0083 | |
5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.0014 | |
Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | 0.0022 | |
Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | 0.0022 | |
Prostaglandin G/H synthase 1 | Homo sapiens (human) | 0.0078 | |
Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | 0.0022 | |
Substance-P receptor | Cavia porcellus (domestic guinea pig) | 0.0015 | |
Mu-type opioid receptor | Homo sapiens (human) | 2.457 | |
Estrogen receptor beta | Homo sapiens (human) | 1.528 | |
Glucocorticoid receptor | Sus scrofa (pig) | 0.0153 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 4 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Buijs, JT; Culig, Z; Grimm, S; Hemmer, DM; Hwang, MS; Kroon, J; Marijt, KA; Masood, M; Meijer, OC; Metselaar, JM; Puhr, M; Storm, G; van der Horst, G; van der Pluijm, G | 1 |
Kucuk, O; Li, X; Mamouni, K; Wu, D; Yang, Y | 1 |
1 review(s) available for docetaxel anhydrous and mifepristone
Article | Year |
---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
3 other study(ies) available for docetaxel anhydrous and mifepristone
Article | Year |
---|---|
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Glucocorticoid receptor antagonism reverts docetaxel resistance in human prostate cancer.
Topics: Apoptosis; Cyproterone Acetate; Docetaxel; Drug Resistance, Neoplasm; Drug Synergism; Gene Expression Regulation, Neoplastic; Hormone Antagonists; Humans; Male; Mifepristone; Prostatic Neoplasms; Receptors, Glucocorticoid; Taxoids; Tumor Cells, Cultured | 2016 |
Mifepristone Has Limited Activity to Enhance the
Topics: Animals; Antineoplastic Agents; Apoptosis; Benzamides; Bone Neoplasms; Cell Proliferation; Docetaxel; Hormone Antagonists; Humans; Male; Mice; Mifepristone; Nitriles; Phenylthiohydantoin; Prostatic Neoplasms, Castration-Resistant; Taxoids; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2017 |