Compounds > docetaxel anhydrous
Page last updated: 2024-09-04

docetaxel anhydrous and elacridar

docetaxel anhydrous has been researched along with elacridar in 5 studies

Compound Research Comparison

Studies
(docetaxel anhydrous)		Trials
(docetaxel anhydrous)		Recent Studies (post-2010)
(docetaxel anhydrous)		Studies
(elacridar)		Trials
(elacridar)		Recent Studies (post-2010) (elacridar)
12,1103,2166,9202848119

Protein Interaction Comparison

ProteinTaxonomydocetaxel anhydrous (IC50)elacridar (IC50)
ATP-dependent translocase ABCB1Homo sapiens (human)0.4427
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)0.2852

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Beijnen, JH; Boogerd, W; Kemper, EM; van Tellingen, O; Verheij, M1
Corcoran, C; Devery, A; Dowling, C; Fan, Y; Fitzpatrick, JM; Gallagher, WM; Mulrane, L; O'Connor, D; O'Connor, R; O'Driscoll, L; O'Neill, AJ; Prencipe, M; Rani, S; Watson, RW1
Ahmad, FJ; Borchard, G; Chaurasiya, A; Jain, GK; Khar, RK; Singh, AK; Sublet, E; Warsi, MH1
Beijnen, JH; Hendrikx, JJ; Lagas, JS; Rosing, H; Schellens, JH; Schinkel, AH; Wagenaar, E1

Other Studies

5 other study(ies) available for docetaxel anhydrous and elacridar

ArticleYear
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
Improved penetration of docetaxel into the brain by co-administration of inhibitors of P-glycoprotein.
    European journal of cancer (Oxford, England : 1990), 2004, Volume: 40, Issue:8

    Topics: Acridines; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Brain Chemistry; Brain Neoplasms; Cyclosporins; Docetaxel; Drug Interactions; Female; Mice; Mice, Knockout; Taxoids; Tetrahydroisoquinolines

2004
Characterisation and manipulation of docetaxel resistant prostate cancer cell lines.
    Molecular cancer, 2011, Oct-07, Volume: 10

    Topics: Acridines; Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; ATP Binding Cassette Transporter, Subfamily B, Member 1; beta-Galactosidase; Cell Line, Tumor; Cell Survival; Cellular Senescence; Docetaxel; Drug Resistance, Neoplasm; Gene Expression; Gene Expression Profiling; Genes, Reporter; Humans; Luciferases, Renilla; Male; Molecular Targeted Therapy; NF-kappa B; Nitriles; Prostatic Neoplasms; Sulfones; Taxoids; Tetrahydroisoquinolines

2011
Dual approach utilizing self microemulsifying technique and novel P-gp inhibitor for effective delivery of taxanes.
    Journal of microencapsulation, 2012, Volume: 29, Issue:6

    Topics: Acridines; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Caco-2 Cells; Docetaxel; Drug Delivery Systems; Drug Screening Assays, Antitumor; Humans; Paclitaxel; Solubility; Taxoids; Tetrahydroisoquinolines

2012
Oral co-administration of elacridar and ritonavir enhances plasma levels of oral paclitaxel and docetaxel without affecting relative brain accumulation.
    British journal of cancer, 2014, May-27, Volume: 110, Issue:11

    Topics: Acridines; Administration, Oral; Animals; Antineoplastic Combined Chemotherapy Protocols; Area Under Curve; Brain; Docetaxel; Humans; Male; Mice; Mice, Knockout; Paclitaxel; Ritonavir; Taxoids; Tetrahydroisoquinolines; Tissue Distribution

2014