Compounds > docetaxel anhydrous
Page last updated: 2024-09-04

docetaxel anhydrous and dactolisib

docetaxel anhydrous has been researched along with dactolisib in 5 studies

Compound Research Comparison

Studies
(docetaxel anhydrous)		Trials
(docetaxel anhydrous)		Recent Studies (post-2010)
(docetaxel anhydrous)		Studies
(dactolisib)		Trials
(dactolisib)		Recent Studies (post-2010) (dactolisib)
12,1103,2166,92044414405

Protein Interaction Comparison

ProteinTaxonomydocetaxel anhydrous (IC50)dactolisib (IC50)
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformRattus norvegicus (Norway rat)0.0053
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoformHomo sapiens (human)0.0692
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alphaHomo sapiens (human)0.034
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit betaHomo sapiens (human)0.044
Bile salt export pumpHomo sapiens (human)7.9
Cytochrome P450 1A2Homo sapiens (human)0.079
Cytochrome P450 2D6Homo sapiens (human)0.079
Phosphatidylinositol 3-kinase regulatory subunit alphaHomo sapiens (human)0.1532
Cytochrome P450 2C19Homo sapiens (human)0.014
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoformHomo sapiens (human)0.0267
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformHomo sapiens (human)0.3474
Serine/threonine-protein kinase mTORHomo sapiens (human)0.0233
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform Homo sapiens (human)0.1022
Tyrosine-protein kinase JAK3Homo sapiens (human)1
Serine-protein kinase ATMHomo sapiens (human)0.007
Regulatory-associated protein of mTORHomo sapiens (human)0.044
Phosphatidylinositol 3-kinase catalytic subunit type 3Homo sapiens (human)0.45
Phosphoinositide 3-kinase regulatory subunit 5Homo sapiens (human)0.1205
Target of rapamycin complex subunit LST8Homo sapiens (human)0.044
Histone deacetylase 6Homo sapiens (human)0.002
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoformRattus norvegicus (Norway rat)0.01

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (80.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Davis, MI; Khan, J; Li, SQ; Patel, PR; Shen, M; Sun, H; Thomas, CJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Kikuchi, E; Kosaka, T; Miyajima, A; Miyazaki, Y; Oya, M; Yasumizu, Y1
Byun, SS; Cheon, J; Hong, SK; Jeong, SJ; Lee, SE; Moon, du G; Oh, MM; Park, HS; Yoon, CY1
Feng, J; Li, B; Liu, J; Ni, S; Wang, D; Wang, L; Zhang, K1

Other Studies

5 other study(ies) available for docetaxel anhydrous and dactolisib

ArticleYear
Identification of potent Yes1 kinase inhibitors using a library screening approach.
    Bioorganic & medicinal chemistry letters, 2013, Aug-01, Volume: 23, Issue:15

    Topics: Binding Sites; Cell Line; Cell Survival; Drug Design; Humans; Hydrogen Bonding; Molecular Docking Simulation; Protein Kinase Inhibitors; Protein Structure, Tertiary; Proto-Oncogene Proteins c-yes; Small Molecule Libraries; Structure-Activity Relationship

2013
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Dual PI3K/mTOR inhibitor NVP-BEZ235 sensitizes docetaxel in castration resistant prostate cancer.
    The Journal of urology, 2014, Volume: 191, Issue:1

    Topics: Animals; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Disease Models, Animal; Docetaxel; Humans; Imidazoles; Male; Mice; Mice, Inbred BALB C; Orchiectomy; Phosphoinositide-3 Kinase Inhibitors; Prostatic Neoplasms, Castration-Resistant; Quinolines; Taxoids; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays

2014
Synergistic antitumor effect of NVP-BEZ235 and sunitinib on docetaxel-resistant human castration-resistant prostate cancer cells.
    Anticancer research, 2014, Volume: 34, Issue:7

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Caspases; Cell Line, Tumor; Docetaxel; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Humans; Imidazoles; Indoles; Male; Phosphorylation; Prostatic Neoplasms, Castration-Resistant; Proto-Oncogene Proteins c-akt; Pyrroles; Quinolines; Sunitinib; Taxoids; Vascular Endothelial Growth Factor Receptor-2

2014
Identification and panoramic analysis of drug response-related genes in triple negative breast cancer using as an example NVP-BEZ235.
    Scientific reports, 2023, 04-12, Volume: 13, Issue:1

    Topics: Cell Line, Tumor; Docetaxel; Humans; Imidazoles; Triple Negative Breast Neoplasms; Tumor Microenvironment

2023