docetaxel anhydrous has been researched along with d-alpha tocopherol in 70 studies
Studies (docetaxel anhydrous) | Trials (docetaxel anhydrous) | Recent Studies (post-2010) (docetaxel anhydrous) | Studies (d-alpha tocopherol) | Trials (d-alpha tocopherol) | Recent Studies (post-2010) (d-alpha tocopherol) |
---|---|---|---|---|---|
12,110 | 3,216 | 6,920 | 32,198 | 2,903 | 7,258 |
Protein | Taxonomy | docetaxel anhydrous (IC50) | d-alpha tocopherol (IC50) |
---|---|---|---|
Glutathione S-transferase P | Homo sapiens (human) | 0.5 |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 5 (7.14) | 29.6817 |
2010's | 56 (80.00) | 24.3611 |
2020's | 9 (12.86) | 2.80 |
Authors | Studies |
---|---|
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
Colomer, R; Lupu, R; Menendez, JA; Ropero, S | 1 |
Erkisi, M; Kara, IO; Sahin, B | 1 |
Branda, RF; Brooks, EM; McCormack, JJ; Naud, SJ; Powden, C; Yildirim, Z | 1 |
Anitha, P; Feng, SS; Gan, CW; Mei, L; Zhou, W | 1 |
Chang, PN; Lee, DT; Ling, MT; Wong, YC; Yap, WN; Yap, YL | 1 |
Feng, SS; Liu, Y; Pan, J | 1 |
Feng, SS; Liu, Y; Mi, Y | 1 |
Chen, H; Huang, L; Liu, K; Liu, R; Mei, L; Song, X; Zeng, X; Zheng, Y | 1 |
Feng, SS; Kulkarni, SA; Muthu, MS; Xiong, J | 1 |
Benhabbour, SR; Feng, L; Ma, P; Mumper, RJ; Wu, H | 1 |
Baek, JS; Cho, CW; Hwang, CJ; Keum, CG; Lim, JH; Na, YG; Noh, YW; Shin, SC | 1 |
Feng, SS; Kulkarni, SA; Muthu, MS; Raju, A | 1 |
Feng, SS; Kulkarni, SA; Liu, Y; Muthu, MS | 1 |
Aota, K; Azuma, M; Harada, M; Kani, K; Momota, Y; Motegi, K; Takano, H; Yamamura, Y; Yamanoi, T | 1 |
Feng, SS; Mi, Y; Zhao, J | 2 |
Feng, SS; Muthu, MS; Raju, A | 1 |
Feng, SS; Huang, L; Mei, L; Tan, C; Tao, W; Zeng, X | 1 |
Chu, M; Guo, Y; Huang, J; Liu, H; Tan, S; Zhang, Z; Zhao, S | 1 |
Huang, L; Liu, T; Mei, L; Ouyang, C; Tao, W; Wang, Z; Xiong, Q; Zeng, X | 1 |
Feng, SS; Kutty, RV | 1 |
Dou, J; Liu, X; Zhai, G; Zhang, H; Zhang, M | 1 |
Bellezza, I; Gatticchi, L; Grottelli, S; Mierla, AL; Minelli, A | 1 |
Cho, HJ; Kim, DD; Park, JW; Yoon, IS | 1 |
Gao, Y; Huang, L; Liu, J; Liu, K; Ma, Y; Mei, L; Ming, P; Tang, X; Wang, Z; Zeng, X; Zhang, J | 1 |
Kulhari, H; Mukherjee, S; Pooja, D; Rachamalla, SS; Singh, MK; Sistla, R | 1 |
Feng, SS; Kutty, RV; Luo, Z; Muthu, MS; Xie, J | 1 |
Feng, X; Jin, X; Liang, Y; Sun, L; Tang, X; Zhang, R | 1 |
Huang, L; Liu, D; Liu, G; Liu, Y; Mei, L; Tao, W; Yu, Q; Zeng, X; Zhang, J; Zhu, X | 1 |
Liang, DS; Liu, YJ; Qi, XR; Wang, AT | 1 |
Adams, DJ; Barui, AK; Kulhari, H; Naidu Vegi, GM; Patra, CR; Pooja, D; Shrivastava, S; Sistla, R; Telukutala, SR | 1 |
Liang, D; Liu, YJ; Qi, XR; Wang, AT; Yang, ZZ | 1 |
Chia, SL; Feng, SS; Kutty, RV; Leong, DT; Muthu, MS; Setyawati, MI | 1 |
Cao, W; Feng, SS; Huang, L; Li, Z; Liu, G; Mei, L; Wang, L; Zeng, X | 1 |
Agrawal, P; Muthu, MS; Pandey, BL; Rajesh, CV; Singh, RP; Singh, S; Vijayakumar, MR | 1 |
Luan, Y; Shi, C; Shi, J; Wang, F; Zhang, Z | 1 |
Liu, G; Mei, L; Tao, W; Wang, T; Zeng, X; Zhang, H; Zhang, L; Zhu, D | 1 |
Gao, L; Hao, D; Liu, G; Ma, J; Wang, X; Wei, P; Zhou, L | 1 |
Di, X; Fu, Q; He, Z; Kan, Q; Li, L; Liu, H; Lu, T; Sun, J; Wang, Y; Zhang, S | 1 |
Koch, B; Kumar, M; Muthu, MS; Pandey, BL; Sharma, G; Singh, RP; Singh, S | 1 |
Dash, D; Koch, B; Muthu, MS; Pandey, BL; Sharma, G; Singh, N; Singh, RP; Singh, S; Singh, U; Vijayakumar, MR | 1 |
Ai, X; Guo, M; Guo, W; He, Z; Liu, D; Ren, G; Wang, M; Wang, Y; Wu, C | 1 |
Feng, JF; Hu, KL; Liu, HL | 1 |
Di, D; Du, Y; Fu, Q; He, Z; Li, L; Luo, C; Pan, X; Ren, G; Sun, B; Sun, J; Wang, M; Zhang, D | 1 |
Li, L; Wang, J; Wang, Y; Xu, L; Xue, P; Zhou, J | 1 |
Fang, X; Ren, X; Sha, X; Wang, X; Zhang, X; Zhong, W | 1 |
Datta, D; Dave, KM; Gayen, JR; Gupta, AP; Mitra, K; Riyazuddin, M; Singh, A; Syed, AA; Valicherla, GR | 1 |
Liu, G; Mei, L; Sheng, Y; Tao, W; Xu, G; Yu, X; Zhang, J | 1 |
Bharti, S; Koch, B; Kumari, L; Muthu, MS; Pandey, BL; Rajinikanth, PS; Sharma, G; Singh, RP; Singh, S | 1 |
Guo, W; He, Z; Jiang, M; Lian, H; Ren, G; Sun, B; Wang, Y | 1 |
Agrawal, P; Koch, B; Kumari, L; Mehata, AK; Muthu, MS; Pandey, BL; Rajesh, CV; Sharma, G; Singh, RP; Singh, S | 1 |
Dang, Z; Du, J; Feng, J; Hu, K; Liu, H; Tu, L; Wang, L; Zhou, Y | 1 |
Deng, Y; Di, D; Shi, J; Song, Y; Tian, Q; Zhao, X | 1 |
Choudhury, H; Gorain, B; Iyer, AK; Kesharwani, P; Kumbhar, SA; Pandey, M; Tekade, RK | 1 |
Adena, SKR; Mishra, B; Mittal, P; Upadhyay, M; Vardhan, H; Yadav, SK | 1 |
Cheng, W; Huang, L; Liang, C; Liu, G; Mei, L; Nie, J; Peng, Y; Zeng, X; Zhang, L; Zhu, D | 1 |
Agrawal, P; Bharti, S; Koch, B; Kumar Mehata, A; Kumari, L; Muthu, MS; Singh, P; Singh, S; Viswanadh, MK | 1 |
Fei, W; Fu, T; Gu, X; Han, T; Hou, Y; Li, N; Liu, Y; Yang, J | 1 |
Chen, X; Huang, X; Lin, G; Liu, G; Ma, J; Mei, L; Shu, X; Wang, X; Wang, Y; Yang, Y; Ying, Y; Zhao, Y; Zuo, A | 1 |
Duan, W; Ha-Lien Tran, P; Tran, TTD; Wang, T; Yang, C | 1 |
Emami, J; Hasanzadeh, F; Kazemi, M; Lavasanifar, A; Minaiyan, M; Mirian, M | 1 |
Ahmad, FJ; Akhter, S; Garg, N; Kumar Jain, G; Selvapandiyan, A; Zafar, S | 1 |
Asay, S; Barnes, B; Graham, A; Hollingsworth, S; Kenealey, JD; Michaelis, DJ; Oblad, RV | 1 |
Gou, G; Li, N; Liu, Q; Mai, Y; Yang, J | 1 |
Gao, J; Liu, J; Lu, Y; Shen, X; Xie, F; Yin, C | 1 |
Bai, P; Chen, L; Liu, H; Qiu, N; Shu, X; Wang, Z; Wen, J; Yang, L; Zhu, Z | 1 |
Kurmi, BD; Paliwal, R; Paliwal, SR; Tekchandani, P | 1 |
Abriata, JP; Chorilli, M; Emery, FDS; Luiz, MT; Marchetti, JM; Tofani, LB; Vaidergorn, MM; Viegas, JSR | 1 |
Deng, Y; Qi, Z; Shi, J; Song, Y | 1 |
2 review(s) available for docetaxel anhydrous and d-alpha tocopherol
Article | Year |
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DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Recent advances in TPGS-based nanoparticles of docetaxel for improved chemotherapy.
Topics: Cell Line, Tumor; Docetaxel; Drug Carriers; Humans; Nanoparticles; Polyethylene Glycols; Taxoids; Vitamin E | 2017 |
68 other study(ies) available for docetaxel anhydrous and d-alpha tocopherol
Article | Year |
---|---|
Omega-6 polyunsaturated fatty acid gamma-linolenic acid (18:3n-6) enhances docetaxel (Taxotere) cytotoxicity in human breast carcinoma cells: Relationship to lipid peroxidation and HER-2/neu expression.
Topics: Antineoplastic Agents, Phytogenic; Antioxidants; Breast Neoplasms; Cell Division; Docetaxel; Drug Synergism; Drug Therapy, Combination; Female; gamma-Linolenic Acid; Humans; Lipid Peroxidation; Oxidative Stress; Receptor, ErbB-2; Taxoids; Tumor Cells, Cultured; Vitamin E | 2004 |
Palmar-plantar erythrodysesthesia due to docetaxel-capecitabine therapy is treated with vitamin E without dose reduction.
Topics: Aged; Antimetabolites, Antineoplastic; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Capecitabine; Carcinoma, Ductal, Breast; Deoxycytidine; Docetaxel; Erythema; Fatal Outcome; Female; Fluorouracil; Foot; Hand; Humans; Middle Aged; Paresthesia; Taxoids; Vitamin E | 2006 |
Vitamin E but not St. John's wort mitigates leukopenia caused by cancer chemotherapy in rats.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cyclophosphamide; Diet; DNA Damage; DNA, Mitochondrial; Docetaxel; Dose-Response Relationship, Drug; Doxorubicin; Female; Hypericum; Leukocyte Count; Leukopenia; Phytotherapy; Plant Preparations; Rats; Rats, Inbred F344; Taxoids; Vitamin E | 2006 |
Poly(lactide)-vitamin E derivative/montmorillonite nanoparticle formulations for the oral delivery of Docetaxel.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Antioxidants; Bentonite; Cell Line; Coumarins; Docetaxel; Drug Carriers; Drug Delivery Systems; Drug Therapy; Humans; Lactic Acid; Male; Nanoparticles; Neoplasms; Particle Size; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Rats; Rats, Sprague-Dawley; Taxoids; Thiazoles; Vitamin E | 2009 |
Evidence of gamma-tocotrienol as an apoptosis-inducing, invasion-suppressing, and chemotherapy drug-sensitizing agent in human melanoma cells.
Topics: Antineoplastic Agents; Apoptosis; Cadherins; Cell Line, Tumor; Cell Proliferation; Chromans; Dacarbazine; Docetaxel; Humans; JNK Mitogen-Activated Protein Kinases; Melanoma; Neoplasm Invasiveness; Signal Transduction; Taxoids; Vitamin E | 2009 |
Multifunctional nanoparticles of biodegradable copolymer blend for cancer diagnosis and treatment.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Membrane Permeability; Cell Survival; Docetaxel; Female; Humans; Lactic Acid; Mice; Nanoparticles; NIH 3T3 Cells; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Quantum Dots; Taxoids; Vitamin E | 2010 |
Formulation of Docetaxel by folic acid-conjugated d-α-tocopheryl polyethylene glycol succinate 2000 (Vitamin E TPGS(2k)) micelles for targeted and synergistic chemotherapy.
Topics: Animals; Cell Line, Tumor; Cell Survival; Docetaxel; Folic Acid; Humans; Mice; Micelles; Microscopy, Confocal; Nanotechnology; NIH 3T3 Cells; Polyethylene Glycols; Polymers; Taxoids; Vitamin E | 2011 |
Nanoformulation of D-α-tocopheryl polyethylene glycol 1000 succinate-b-poly(ε-caprolactone-ran-glycolide) diblock copolymer for breast cancer therapy.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Docetaxel; Female; Humans; Magnetic Resonance Spectroscopy; Mice; Mice, SCID; Microscopy, Electron, Scanning; Nanoparticles; Polyesters; Polyethylene Glycols; Polyglycolic Acid; Random Allocation; Taxoids; Vitamin E; Xenograft Model Antitumor Assays | 2011 |
Vitamin E TPGS coated liposomes enhanced cellular uptake and cytotoxicity of docetaxel in brain cancer cells.
Topics: Absorption; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Coumarins; Docetaxel; Glioma; Humans; Liposomes; Microscopy, Atomic Force; Microscopy, Confocal; Microscopy, Electron, Transmission; Particle Size; Polyethylene Glycols; Taxoids; Thiazoles; Vitamin E | 2011 |
Development and optimization of oil-filled lipid nanoparticles containing docetaxel conjugates designed to control the drug release rate in vitro and in vivo.
Topics: Analysis of Variance; Animals; Area Under Curve; Cell Line, Tumor; Cell Survival; Delayed-Action Preparations; Docetaxel; Drug Carriers; Fatty Acids; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Polyethylene Glycols; Solubility; Taxoids; Triglycerides; Vitamin E | 2011 |
Practical preparation procedures for docetaxel-loaded nanoparticles using polylactic acid-co-glycolic acid.
Topics: Acetates; Centrifugation; Chloroform; Docetaxel; Lactic Acid; Nanocapsules; Nanoparticles; Particle Size; Photoelectron Spectroscopy; Poloxamer; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polyvinyl Alcohol; Sonication; Surface Tension; Surface-Active Agents; Taxoids; Vitamin E | 2011 |
Theranostic liposomes of TPGS coating for targeted co-delivery of docetaxel and quantum dots.
Topics: Breast Neoplasms; Cell Line, Tumor; Cell Survival; Docetaxel; Female; Humans; Liposomes; Polyethylene Glycols; Quantum Dots; Radiation-Sensitizing Agents; Taxoids; Vitamin E | 2012 |
Development of docetaxel-loaded vitamin E TPGS micelles: formulation optimization, effects on brain cancer cells and biodistribution in rats.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Docetaxel; Drug Carriers; Glioma; Humans; Male; Micelles; Polyethylene Glycols; Rats; Rats, Sprague-Dawley; Taxoids; Vitamin E | 2012 |
γ-tocotrienol enhances the chemosensitivity of human oral cancer cells to docetaxel through the downregulation of the expression of NF-κB-regulated anti-apoptotic gene products.
Topics: Antineoplastic Agents; Apoptosis; Apoptosis Regulatory Proteins; Blotting, Western; Caspase 3; Cell Nucleus; Cell Proliferation; Chromans; Cytoplasm; Docetaxel; Down-Regulation; Drug Resistance, Neoplasm; Electrophoretic Mobility Shift Assay; Humans; Mouth Neoplasms; NF-kappa B; Peptide Library; Poly(ADP-ribose) Polymerases; Taxoids; Tumor Cells, Cultured; Vitamin E | 2013 |
Targeted co-delivery of docetaxel and siPlk1 by herceptin-conjugated vitamin E TPGS based immunomicelles.
Topics: Animals; Antibodies, Monoclonal, Humanized; Cell Cycle Proteins; Cell Division; Cell Line; Cell Survival; Chromatography, High Pressure Liquid; Cytoplasm; Docetaxel; Drug Delivery Systems; Gene Transfer Techniques; Humans; Inhibitory Concentration 50; Light; Mice; Micelles; Microscopy, Electron, Transmission; Particle Size; Polo-Like Kinase 1; Polyethylene Glycols; Protein Serine-Threonine Kinases; Proto-Oncogene Proteins; RNA, Small Interfering; Scattering, Radiation; Taxoids; Time-Lapse Imaging; Transfection; Trastuzumab; Vitamin E | 2013 |
Targeted co-delivery of docetaxel, cisplatin and herceptin by vitamin E TPGS-cisplatin prodrug nanoparticles for multimodality treatment of cancer.
Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Breast; Breast Neoplasms; Cell Line, Tumor; Cisplatin; Docetaxel; Drug Carriers; Female; Humans; Mice; Nanoparticles; NIH 3T3 Cells; Polyethylene Glycols; Prodrugs; Taxoids; Trastuzumab; Vitamin E | 2013 |
Trastuzumab-conjugated vitamin E TPGS liposomes for sustained and targeted delivery of docetaxel.
Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Area Under Curve; Breast Neoplasms; Calorimetry, Differential Scanning; Cell Line, Tumor; Cell Survival; Chemistry, Pharmaceutical; Chromatography, High Pressure Liquid; Coumarins; Docetaxel; Drug Carriers; Half-Life; Humans; Liposomes; Male; Microscopy, Confocal; Particle Size; Polyethylene Glycols; Rats, Sprague-Dawley; Receptor, ErbB-2; Spectroscopy, Fourier Transform Infrared; Taxoids; Thiazoles; Trastuzumab; Vitamin E | 2013 |
Cholic acid-functionalized nanoparticles of star-shaped PLGA-vitamin E TPGS copolymer for docetaxel delivery to cervical cancer.
Topics: Animals; Antineoplastic Agents; Cholic Acid; Docetaxel; Female; HeLa Cells; Humans; Lactic Acid; Mice; Mice, SCID; Nanomedicine; Nanoparticles; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Taxoids; Uterine Cervical Neoplasms; Vitamin E; Xenograft Model Antitumor Assays | 2013 |
pH-sensitive docetaxel-loaded D-α-tocopheryl polyethylene glycol succinate-poly(β-amino ester) copolymer nanoparticles for overcoming multidrug resistance.
Topics: Antineoplastic Agents; Apoptosis; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Docetaxel; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Hydrogen-Ion Concentration; Nanoparticles; Particle Size; Polyethylene Glycols; Polymers; Taxoids; Vitamin E | 2013 |
Docetaxel-loaded nanoparticles based on star-shaped mannitol-core PLGA-TPGS diblock copolymer for breast cancer therapy.
Topics: Antineoplastic Agents; Breast Neoplasms; Calorimetry, Differential Scanning; Cell Survival; Chromatography, Gel; Coumarins; Docetaxel; Female; Humans; Inhibitory Concentration 50; Lactic Acid; Magnetic Resonance Spectroscopy; Mannitol; MCF-7 Cells; Molecular Weight; Nanoparticles; Particle Size; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Static Electricity; Taxoids; Thermogravimetry; Thiazoles; Vitamin E; Xenograft Model Antitumor Assays | 2013 |
Cetuximab conjugated vitamin E TPGS micelles for targeted delivery of docetaxel for treatment of triple negative breast cancers.
Topics: Animals; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Cell Line, Tumor; Cetuximab; Docetaxel; Humans; Mice; Micelles; Nanomedicine; Nanotechnology; Taxoids; Triple Negative Breast Neoplasms; Vitamin E | 2013 |
Preparation and evaluation in vitro and in vivo of docetaxel loaded mixed micelles for oral administration.
Topics: Administration, Oral; Animals; Chitosan; Docetaxel; Gastrointestinal Tract; Magnetic Resonance Spectroscopy; Male; Micelles; Microscopy, Electron, Transmission; Molecular Weight; Oligosaccharides; Rats; Rats, Wistar; Stearic Acids; Taxoids; Time Factors; Vitamin E | 2014 |
α-Tocopheryl succinate pre-treatment attenuates quinone toxicity in prostate cancer PC3 cells.
Topics: Active Transport, Cell Nucleus; alpha-Tocopherol; Antioxidants; Apoptosis; Benzoquinones; Cell Line, Tumor; Cell Proliferation; Cell Survival; DNA-Binding Proteins; Docetaxel; Drug Resistance, Neoplasm; Enzyme Activation; Enzyme Inhibitors; Glutathione; Heme Oxygenase-1; Humans; Hydrogen Peroxide; Hydroquinones; Male; NAD(P)H Dehydrogenase (Quinone); NF-E2-Related Factor 2; Oxidative Stress; Paraquat; Prostatic Neoplasms; Protoporphyrins; RNA Interference; RNA, Small Interfering; Taxoids | 2014 |
Surface-modified solid lipid nanoparticles for oral delivery of docetaxel: enhanced intestinal absorption and lymphatic uptake.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Docetaxel; Drug Delivery Systems; Intestinal Absorption; Lipids; Lymphatic System; Male; Nanomedicine; Nanoparticles; Polyethylene Glycols; Polysorbates; Rats; Rats, Sprague-Dawley; Surface Properties; Taxoids; Triglycerides; Vitamin E | 2014 |
Antitumor efficiency of D-alpha-tocopheryl polyethylene glycol 1000 succinate-b-poly(epsilon-caprolactone-ran-lactide) nanoparticle-based delivery of docetaxel in mice bearing cervical cancer.
Topics: alpha-Tocopherol; Animals; Antineoplastic Agents; Cell Line, Tumor; Docetaxel; Drug Carriers; Female; Humans; Mice; Nanoparticles; Polyesters; Polyethylene Glycols; Succinates; Taxoids; Uterine Cervical Neoplasms; Xenograft Model Antitumor Assays | 2014 |
Dendrimer-TPGS mixed micelles for enhanced solubility and cellular toxicity of taxanes.
Topics: Animals; Cell Death; Cell Line; Cell Survival; Dendrimers; Docetaxel; Hemolysis; Humans; Hydrogen-Ion Concentration; Micelles; Paclitaxel; Particle Size; Polyethylene Glycols; Rats; Solubility; Spectroscopy, Fourier Transform Infrared; Static Electricity; Taxoids; Vitamin E; X-Ray Diffraction | 2014 |
Theranostic vitamin E TPGS micelles of transferrin conjugation for targeted co-delivery of docetaxel and ultra bright gold nanoclusters.
Topics: Animals; Breast Neoplasms; Cell Line; Docetaxel; Drug Carriers; Flow Cytometry; Gold; Humans; Metal Nanoparticles; Mice; Mice, SCID; Micelles; Microscopy, Electron, Transmission; NIH 3T3 Cells; Particle Size; Polyethylene Glycols; Taxoids; Transferrin; Vitamin E | 2015 |
Co-delivery of docetaxel and Poloxamer 235 by PLGA-TPGS nanoparticles for breast cancer treatment.
Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Docetaxel; Drug Carriers; Drug Resistance, Multiple; Female; Humans; Lactic Acid; MCF-7 Cells; Nanoparticles; Particle Size; Poloxamer; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Taxoids; Vitamin E | 2015 |
Blended nanoparticle system based on miscible structurally similar polymers: a safe, simple, targeted, and surprisingly high efficiency vehicle for cancer therapy.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biocompatible Materials; Cell Line, Tumor; Cell Survival; Docetaxel; Drug Delivery Systems; Drug Resistance, Neoplasm; Endocytosis; Female; Folic Acid; HeLa Cells; Humans; MCF-7 Cells; Mice; Mice, SCID; Nanoparticles; Neoplasms; Particle Size; Polyethylene Glycols; Polyglactin 910; Polyglycolic Acid; Polymers; Taxoids; Vitamin E | 2015 |
Roles of ligand and TPGS of micelles in regulating internalization, penetration and accumulation against sensitive or resistant tumor and therapy for multidrug resistant tumors.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Proliferation; Docetaxel; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Ligands; Membrane Potential, Mitochondrial; Mice; Mice, Inbred BALB C; Micelles; Polyethylene Glycols; Taxoids; Vitamin E | 2015 |
Cyclic-RGDfK peptide conjugated succinoyl-TPGS nanomicelles for targeted delivery of docetaxel to integrin receptor over-expressing angiogenic tumours.
Topics: Antineoplastic Agents, Phytogenic; Cell Line, Tumor; Docetaxel; Human Umbilical Vein Endothelial Cells; Humans; Integrins; Male; Micelles; Nanostructures; Neovascularization, Pathologic; Peptides, Cyclic; Polyethylene Glycols; Prostatic Neoplasms; Receptors, Cell Surface; Taxoids; Vitamin E | 2015 |
Enhance Cancer Cell Recognition and Overcome Drug Resistance Using Hyaluronic Acid and α-Tocopheryl Succinate Based Multifunctional Nanoparticles.
Topics: alpha-Tocopherol; Animals; Apoptosis; Cell Line, Tumor; Docetaxel; Drug Resistance, Neoplasm; Female; Humans; Hyaluronic Acid; MCF-7 Cells; Mice; Mice, Nude; Nanoparticles; Taxoids; X-Ray Diffraction | 2015 |
In vivo and ex vivo proofs of concept that cetuximab conjugated vitamin E TPGS micelles increases efficacy of delivered docetaxel against triple negative breast cancer.
Topics: Animals; Antineoplastic Agents; Breast; Cell Line, Tumor; Cetuximab; Docetaxel; Drug Carriers; Drug Delivery Systems; Female; Humans; Mice, SCID; Micelles; Polyethylene Glycols; Taxoids; Triple Negative Breast Neoplasms; Vitamin E | 2015 |
Porphine functionalized nanoparticles of star-shaped poly(ε-caprolactone)-b-D-α-tocopheryl polyethylene glycol 1000 succinate biodegradable copolymer for chemophotodynamic therapy on cervical cancer.
Topics: Absorbable Implants; Antineoplastic Agents; Combined Modality Therapy; Delayed-Action Preparations; Diffusion; Docetaxel; Female; HeLa Cells; Humans; MCF-7 Cells; Nanocapsules; Photochemotherapy; Polyesters; Polyethylene Glycols; Porphyrins; Radiation-Sensitizing Agents; Taxoids; Treatment Outcome; Uterine Cervical Neoplasms; Vitamin E | 2015 |
Transferrin receptor-targeted vitamin E TPGS micelles for brain cancer therapy: preparation, characterization and brain distribution in rats.
Topics: Animals; Blood-Brain Barrier; Brain Neoplasms; Cell Line, Tumor; Docetaxel; Drug Carriers; Drug Liberation; Micelles; Particle Size; Rats; Receptors, Transferrin; Taxoids; Vitamin E | 2016 |
Co-delivery of docetaxel and chloroquine via PEO-PPO-PCL/TPGS micelles for overcoming multidrug resistance.
Topics: Antineoplastic Agents; Cell Death; Cell Line, Tumor; Chloroquine; Docetaxel; Drug Combinations; Drug Delivery Systems; Drug Liberation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Hemolysis; Humans; Micelles; Polyesters; Polyethylene Glycols; Taxoids; Vitamin E | 2015 |
Docetaxel (DTX)-loaded polydopamine-modified TPGS-PLA nanoparticles as a targeted drug delivery system for the treatment of liver cancer.
Topics: Animals; Carcinoma, Hepatocellular; Docetaxel; Drug Delivery Systems; Hep G2 Cells; Humans; Indoles; Lactic Acid; Liver Neoplasms, Experimental; Mice; Mice, Nude; Nanoparticles; Polyesters; Polyethylene Glycols; Polymers; Taxoids; Vitamin E; Xenograft Model Antitumor Assays | 2016 |
Evaluation of TPGS-modified thermo-sensitive Pluronic PF127 hydrogel as a potential carrier to reverse the resistance of P-gp-overexpressing SMMC-7721 cell lines.
Topics: Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blotting, Western; Cell Line, Tumor; Cell Survival; Docetaxel; Drug Carriers; Drug Evaluation, Preclinical; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Hydrogel, Polyethylene Glycol Dimethacrylate; Liver Neoplasms; Mice, Inbred BALB C; Mice, Nude; Microscopy, Electron, Scanning; Poloxamer; Polyethylene Glycols; Taxoids; Temperature; Tumor Burden; Vitamin E; Xenograft Model Antitumor Assays | 2016 |
Large amino acid transporter 1 mediated glutamate modified docetaxel-loaded liposomes for glioma targeting.
Topics: Animals; Antineoplastic Agents; Blood-Brain Barrier; Calorimetry, Differential Scanning; Cell Line, Tumor; Cell Survival; Docetaxel; Drug Carriers; Drug Liberation; Glioma; Glutamic Acid; Large Neutral Amino Acid-Transporter 1; Liposomes; Male; Mice; Microscopy, Confocal; Microscopy, Electron, Transmission; Taxoids; Vitamin E | 2016 |
Vitamin E TPGS conjugated carbon nanotubes improved efficacy of docetaxel with safety for lung cancer treatment.
Topics: A549 Cells; Alkaline Phosphatase; Animals; Antineoplastic Agents; Apoptosis; Bronchoalveolar Lavage Fluid; Cell Cycle; Cell Survival; Coated Materials, Biocompatible; Coumarins; Docetaxel; Drug Liberation; Humans; L-Lactate Dehydrogenase; Lung; Lung Neoplasms; Microscopy, Electron, Transmission; Microscopy, Fluorescence; Nanotubes, Carbon; Rats; Reactive Oxygen Species; Spectroscopy, Fourier Transform Infrared; Spectrum Analysis, Raman; Taxoids; Thiazoles; Vitamin E | 2016 |
Transferrin liposomes of docetaxel for brain-targeted cancer applications: formulation and brain theranostics.
Topics: Blood-Brain Barrier; Brain; Brain Neoplasms; Cell Line, Tumor; Chemistry, Pharmaceutical; Docetaxel; Drug Carriers; Humans; Liposomes; Permeability; Polyethylene Glycols; Quantum Dots; Taxoids; Theranostic Nanomedicine; Transferrin; Vitamin E | 2016 |
Docetaxel prodrug liposomes for tumor therapy: characterization, in vitro and in vivo evaluation.
Topics: Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Docetaxel; Drug Carriers; Humans; Liposomes; Lung Neoplasms; Nanoparticles; Taxoids; Vitamin E; Xenograft Model Antitumor Assays | 2016 |
[Development and characterization of TPGS modified proniosomes of docetaxel].
Topics: Chemistry, Pharmaceutical; Docetaxel; Particle Size; Polyethylene Glycols; Taxoids; Vitamin E | 2015 |
Core-matched encapsulation of an oleate prodrug into nanostructured lipid carriers with high drug loading capability to facilitate the oral delivery of docetaxel.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Biological Availability; Biological Transport; Docetaxel; Dogs; Drug Carriers; Drug Compounding; Endocytosis; Glycerides; Hydrophobic and Hydrophilic Interactions; Intestinal Absorption; Intestinal Mucosa; Intestines; Madin Darby Canine Kidney Cells; Nanostructures; Oleic Acids; Particle Size; Prodrugs; Rats; Rats, Sprague-Dawley; Taxoids; Tissue Distribution; Vitamin E | 2016 |
Comparison of two kinds of docetaxel-vitamin E prodrugs: In vitro evaluation and in vivo antitumor activity.
Topics: Animals; Antineoplastic Agents; Area Under Curve; Cell Line, Tumor; Chemistry, Pharmaceutical; Docetaxel; Female; Half-Life; Humans; Inhibitory Concentration 50; Liposomes; Lung Neoplasms; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Prodrugs; Prostatic Neoplasms; Rats; Rats, Sprague-Dawley; Taxoids; Vitamin E; Xenograft Model Antitumor Assays | 2016 |
Matrix metalloproteinases-2/9-sensitive peptide-conjugated polymer micelles for site-specific release of drugs and enhancing tumor accumulation: preparation and in vitro and in vivo evaluation.
Topics: alpha-Tocopherol; Animals; Cell Death; Cell Line, Tumor; Diagnostic Imaging; Docetaxel; Drug Delivery Systems; Drug Liberation; Endocytosis; Fluorescence Resonance Energy Transfer; Humans; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Mice, Inbred BALB C; Mice, Nude; Micelles; Neoplasms; Peptides; Polyethylene Glycols; Polymers; Proton Magnetic Resonance Spectroscopy; Subcellular Fractions; Taxoids; Vitamin E | 2016 |
Formulation optimization of Docetaxel loaded self-emulsifying drug delivery system to enhance bioavailability and anti-tumor activity.
Topics: Animals; Antineoplastic Agents; Biological Availability; Breast Neoplasms; Cell Survival; Docetaxel; Drug Compounding; Drug Delivery Systems; Drug Stability; Emulsions; Ethylene Glycols; Female; Humans; Male; MCF-7 Cells; Mice, Inbred BALB C; Polyethylene Glycols; Polymers; Propylene Glycols; Rats; Rats, Sprague-Dawley; Solubility; Taxoids; Vitamin E; Xenograft Model Antitumor Assays | 2016 |
Robust aptamer-polydopamine-functionalized M-PLGA-TPGS nanoparticles for targeted delivery of docetaxel and enhanced cervical cancer therapy.
Topics: Animals; Antineoplastic Agents; Aptamers, Nucleotide; Docetaxel; Drug Carriers; Drug Delivery Systems; Female; HeLa Cells; Humans; Indoles; Lactic Acid; Mice, SCID; Nanoparticles; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Taxoids; Uterine Cervical Neoplasms; Vitamin E; Xenograft Model Antitumor Assays | 2016 |
RGD-TPGS decorated theranostic liposomes for brain targeted delivery.
Topics: Animals; Antineoplastic Agents; Brain; Brain Neoplasms; Docetaxel; Drug Carriers; Drug Delivery Systems; Drug Liberation; Liposomes; Nanoparticles; Quantum Dots; Rats; Rats, Inbred Strains; Reactive Oxygen Species; Taxoids; Theranostic Nanomedicine; Vitamin E | 2016 |
Construction and cellular uptake behavior of redox-sensitive docetaxel prodrug-loaded liposomes.
Topics: A549 Cells; Antineoplastic Agents; Biological Transport; Cell Line, Tumor; Chemistry, Pharmaceutical; Docetaxel; Drug Carriers; Humans; Lipids; Liposomes; Oxidation-Reduction; Particle Size; Prodrugs; Taxoids; Vitamin E | 2018 |
TPGS-chitosan cross-linked targeted nanoparticles for effective brain cancer therapy.
Topics: alpha-Tocopherol; Animals; Brain Neoplasms; Cell Line, Tumor; Cell Survival; Chitosan; Docetaxel; Drug Carriers; Female; Half-Life; Humans; Male; Microscopy, Electron, Scanning; Microscopy, Fluorescence; Nanoparticles; Particle Size; Rats; Receptors, Transferrin; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Taxoids | 2017 |
Improved Bioavailability and Antitumor Effect of Docetaxel by TPGS Modified Proniosomes: In Vitro and In Vivo Evaluations.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Biological Availability; Breast Neoplasms; Caco-2 Cells; Disease Models, Animal; Docetaxel; Drug Carriers; Humans; Liposomes; Mice; Taxoids; Treatment Outcome; Vitamin E | 2017 |
The antitumor efficacy of docetaxel is enhanced by encapsulation in novel amphiphilic polymer cholesterol-coupled tocopheryl polyethylene glycol 1000 succinate micelles.
Topics: Animals; Cell Line, Tumor; Cell Proliferation; Cell Survival; Chemistry, Pharmaceutical; Cholesterol; Docetaxel; Mice; Micelles; Particle Size; Sarcoma, Experimental; Taxoids; Vitamin E; Xenograft Model Antitumor Assays | 2017 |
Process optimization and in vivo performance of docetaxel loaded PHBV-TPGS therapeutic vesicles: A synergistic approach.
Topics: Animals; Antineoplastic Agents; Biocompatible Materials; Calorimetry, Differential Scanning; Cell Survival; Chromatography, High Pressure Liquid; Colloids; Disease Models, Animal; Docetaxel; Drug Carriers; Drug Compounding; Drug Delivery Systems; Drug Liberation; Humans; Hydrogen-Ion Concentration; Mice; Nanoparticles; Particle Size; Polyesters; Spectroscopy, Fourier Transform Infrared; Taxoids; Vitamin E; X-Ray Diffraction; Xenograft Model Antitumor Assays | 2018 |
A multifunctional nanoplatform for cancer chemo-photothermal synergistic therapy and overcoming multidrug resistance.
Topics: Animals; Antineoplastic Agents; Docetaxel; Dopamine; Drug Liberation; Drug Resistance, Neoplasm; Female; Humans; Lactic Acid; Mammary Neoplasms, Experimental; MCF-7 Cells; Mice; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Phototherapy; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Taxoids; Vitamin E | 2018 |
Trastuzumab decorated TPGS-g-chitosan nanoparticles for targeted breast cancer therapy.
Topics: Adenocarcinoma; Animals; Antineoplastic Agents; Biological Availability; Breast Neoplasms; Cell Line, Tumor; Chitosan; Docetaxel; Drug Carriers; Female; Glycoconjugates; Humans; Kidney; Liver; Lung; Molecular Targeted Therapy; Nanoparticles; Rats; Receptor, ErbB-2; Trastuzumab; Tumor Burden; Vitamin E; Xenograft Model Antitumor Assays | 2019 |
Vitamin E D-alpha-tocopheryl polyethylene glycol 1000 succinate-conjugated liposomal docetaxel reverses multidrug resistance in breast cancer cells.
Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Line, Tumor; Cell Survival; Docetaxel; Drug Delivery Systems; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Liposomes; MCF-7 Cells; Particle Size; Polyethylene Glycols; Succinates; Vitamin E | 2019 |
Docetaxel-loaded PAMAM-based poly (γ-benzyl-l-glutamate)-b-d-α-tocopheryl polyethylene glycol 1000 succinate nanoparticles in human breast cancer and human cervical cancer therapy.
Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Dendrimers; Docetaxel; Drug Carriers; Drug Liberation; Female; HeLa Cells; Humans; MCF-7 Cells; Mice, Inbred BALB C; Mice, Nude; Uterine Cervical Neoplasms; Vitamin E | 2019 |
Development of conjugate-by-conjugate structured nanoparticles for oral delivery of docetaxel.
Topics: Administration, Oral; Antineoplastic Agents; Breast Neoplasms; Caco-2 Cells; Cell Line, Tumor; Chitosan; Docetaxel; Drug Carriers; Drug Delivery Systems; Female; Humans; Hydrogen-Ion Concentration; Hypromellose Derivatives; Intestinal Absorption; Nanoparticles; Particle Size; Vitamin E; X-Ray Diffraction | 2020 |
Novel pH-triggered biocompatible polymeric micelles based on heparin-α-tocopherol conjugate for intracellular delivery of docetaxel in breast cancer.
Topics: alpha-Tocopherol; Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Delayed-Action Preparations; Docetaxel; Drug Liberation; Female; Heparin; Humans; Hydrogen-Ion Concentration; MCF-7 Cells; Mice; Micelles | 2020 |
Co-encapsulation of docetaxel and thymoquinone in mPEG-DSPE-vitamin E TPGS-lipid nanocapsules for breast cancer therapy: Formulation optimization and implications on cellular and in vivo toxicity.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Benzoquinones; Breast Neoplasms; Cell Line, Tumor; Cell Movement; Docetaxel; Drug Resistance, Neoplasm; Female; Humans; MCF-7 Cells; Mice; Mice, Inbred BALB C; Nanocapsules; Phosphatidylethanolamines; Polyethylene Glycols; Triple Negative Breast Neoplasms; Vitamin E | 2020 |
γ-Tocotrienol and α-Tocopherol Ether Acetate Enhance Docetaxel Activity in Drug-Resistant Prostate Cancer Cells.
Topics: alpha-Tocopherol; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Chromans; Docetaxel; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; Drug Synergism; Ether; Humans; Male; Prostatic Neoplasms; Vitamin E | 2020 |
Docetaxel-loaded D-α-tocopheryl polyethylene glycol-1000 succinate liposomes improve lung cancer chemotherapy and reverse multidrug resistance.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Docetaxel; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Liposomes; Lung Neoplasms; Mice; Mice, Nude; Polyethylene Glycols; Succinates; Vitamin E | 2021 |
Co-Delivery of Docetaxel and Salinomycin to Target Both Breast Cancer Cells and Stem Cells by PLGA/TPGS Nanoparticles.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Docetaxel; Drug Delivery Systems; Drug Liberation; Female; Humans; Liposomes; Male; MCF-7 Cells; Mice, Inbred BALB C; Nanoparticles; Neoplastic Stem Cells; Polylactic Acid-Polyglycolic Acid Copolymer; Pyrans; Rats, Sprague-Dawley; Tissue Distribution; Vitamin E; Xenograft Model Antitumor Assays | 2019 |
Antitumor Effects of Docetaxel in Truncated Basic Fibroblast Growth Factor- Functionalized Liposomes Delivered by d-α-tocopheryl Polyethylene Glycol 2000 Succinate.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Docetaxel; Fibroblast Growth Factor 2; Liposomes; Mice; Mice, Inbred C57BL; Polyethylene Glycols; Succinates; Vitamin E | 2020 |
Galactosylated TPGS Micelles for Docetaxel Targeting to Hepatic Carcinoma: Development, Characterization, and Biodistribution Study.
Topics: Animals; Antineoplastic Agents; Carcinoma, Hepatocellular; Cell Line, Tumor; Docetaxel; Drug Delivery Systems; Drug Development; Female; Galactose; Hep G2 Cells; Humans; Liver Neoplasms; Male; Random Allocation; Rats; Tissue Distribution; Vitamin E | 2020 |
Docetaxel-loaded folate-modified TPGS-transfersomes for glioblastoma multiforme treatment.
Topics: Antineoplastic Agents; Cell Line, Tumor; Docetaxel; Drug Carriers; Folic Acid; Glioblastoma; Humans; Nanoparticles; Vitamin E | 2021 |
A novel micellar carrier to reverse multidrug resistance of tumours: TPGS derivatives with end-grafted cholesterol.
Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Cholesterol; Docetaxel; Drug Resistance, Multiple; Female; Humans; Mice; Mice, Nude; Micelles; Ovarian Neoplasms; Polyethylene Glycols; Vitamin E | 2023 |