Page last updated: 2024-09-04

docetaxel anhydrous and cyclopamine

docetaxel anhydrous has been researched along with cyclopamine in 5 studies

Compound Research Comparison

Studies
(docetaxel anhydrous)
Trials
(docetaxel anhydrous)
Recent Studies (post-2010)
(docetaxel anhydrous)
Studies
(cyclopamine)
Trials
(cyclopamine)
Recent Studies (post-2010) (cyclopamine)
12,1103,2166,9206580343

Protein Interaction Comparison

ProteinTaxonomydocetaxel anhydrous (IC50)cyclopamine (IC50)
Integrin beta-1Homo sapiens (human)1.312
Integrin alpha-4Homo sapiens (human)1.312
Smoothened homologMus musculus (house mouse)1.271
Sonic hedgehog proteinHomo sapiens (human)0.6
Sonic hedgehog proteinMus musculus (house mouse)0.7373
Smoothened homologHomo sapiens (human)0.2147

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (20.00)29.6817
2010's4 (80.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Batra, SK; Depreux, P; Henichart, JP; Johansson, SL; Lin, MF; Mimeault, M; Moore, E; Vankatraman, G1
Batra, SK; Depreux, P; Henichart, JP; Johansson, SL; Mimeault, M1
Dietz, A; Dimitrova, K; Mozet, C; Stoehr, M; Wichmann, G1
Kopeček, J; Rhim, JS; Yang, J; Zhou, Y1
Almawash, SA; Mahato, RI; Mondal, G1

Other Studies

5 other study(ies) available for docetaxel anhydrous and cyclopamine

ArticleYear
Combined targeting of epidermal growth factor receptor and hedgehog signaling by gefitinib and cyclopamine cooperatively improves the cytotoxic effects of docetaxel on metastatic prostate cancer cells.
    Molecular cancer therapeutics, 2007, Volume: 6, Issue:3

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Blotting, Western; Cell Movement; Cell Proliferation; Cytochromes c; Docetaxel; ErbB Receptors; Gefitinib; Hedgehog Proteins; Humans; Immunohistochemistry; Male; Membrane Potential, Mitochondrial; Neoplasm Invasiveness; Neoplasms, Hormone-Dependent; Prostatic Neoplasms; Quinazolines; Signal Transduction; Taxoids; Tumor Cells, Cultured; Veratrum Alkaloids

2007
Cytotoxic effects induced by docetaxel, gefitinib, and cyclopamine on side population and nonside population cell fractions from human invasive prostate cancer cells.
    Molecular cancer therapeutics, 2010, Volume: 9, Issue:3

    Topics: Adenocarcinoma; Apoptosis; Cell Fractionation; Cell Line, Tumor; Cell Proliferation; Cytotoxins; Docetaxel; Drug Evaluation, Preclinical; ErbB Receptors; Gefitinib; Humans; Male; Neoplasm Invasiveness; Phosphorylation; Prostate; Prostatic Neoplasms; Quinazolines; Taxoids; Transcription Factors; Veratrum Alkaloids; Zinc Finger Protein GLI1

2010
Hedgehog targeting by cyclopamine suppresses head and neck squamous cell carcinoma and enhances chemotherapeutic effects.
    Anticancer research, 2013, Volume: 33, Issue:6

    Topics: Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Cisplatin; Docetaxel; Female; Head and Neck Neoplasms; Hedgehog Proteins; Humans; KB Cells; Keratins; Male; Molecular Targeted Therapy; Receptors, G-Protein-Coupled; Signal Transduction; Smoothened Receptor; Taxoids; Tumor Cells, Cultured; Tumor Stem Cell Assay; Veratrum Alkaloids

2013
HPMA copolymer-based combination therapy toxic to both prostate cancer stem/progenitor cells and differentiated cells induces durable anti-tumor effects.
    Journal of controlled release : official journal of the Controlled Release Society, 2013, Dec-28, Volume: 172, Issue:3

    Topics: Animals; Antineoplastic Agents; Cell Differentiation; Cell Line, Tumor; Docetaxel; Drug Delivery Systems; Humans; Male; Methacrylates; Mice; Mice, Nude; Neoplastic Stem Cells; Prostate; Prostatic Neoplasms; Taxoids; Veratrum Alkaloids

2013
Coadministration of Polymeric Conjugates of Docetaxel and Cyclopamine Synergistically Inhibits Orthotopic Pancreatic Cancer Growth and Metastasis.
    Pharmaceutical research, 2018, 01-05, Volume: 35, Issue:1

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cell Line, Tumor; Cell Survival; Docetaxel; Drug Carriers; Drug Liberation; Hedgehogs; Humans; Mice; Micelles; Microtubules; Neoplasm Metastasis; Pancreatic Neoplasms; Polymers; Proton Magnetic Resonance Spectroscopy; Taxoids; Veratrum Alkaloids

2018