Page last updated: 2024-09-04

docetaxel anhydrous and curcumin

docetaxel anhydrous has been researched along with curcumin in 35 studies

Compound Research Comparison

Studies
(docetaxel anhydrous)
Trials
(docetaxel anhydrous)
Recent Studies (post-2010)
(docetaxel anhydrous)
Studies
(curcumin)
Trials
(curcumin)
Recent Studies (post-2010) (curcumin)
12,1103,2166,92016,33659312,705

Protein Interaction Comparison

ProteinTaxonomydocetaxel anhydrous (IC50)curcumin (IC50)
toll-like receptor 9Homo sapiens (human)8.362
TPA: protein transporter TIM10Saccharomyces cerevisiae S288C19.7
intestinal alkaline phosphatase precursorMus musculus (house mouse)18.7
perilipin-1Homo sapiens (human)9.167
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform aHomo sapiens (human)9.167
hypothetical protein SA1422Staphylococcus aureus subsp. aureus N31542.9
Prostaglandin E synthaseHomo sapiens (human)1.8
Lysine-specific histone demethylase 1AHomo sapiens (human)9.6
D-amino-acid oxidaseSus scrofa (pig)1.07
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1Oryctolagus cuniculus (rabbit)3
Amyloid-beta precursor proteinHomo sapiens (human)4.3079
Neuronal proto-oncogene tyrosine-protein kinase Src Mus musculus (house mouse)2.2
Heme oxygenase 1 Rattus norvegicus (Norway rat)10
Microtubule-associated protein tauHomo sapiens (human)3.25
60 kDa heat shock protein, mitochondrialHomo sapiens (human)8.3
Tissue factorHomo sapiens (human)0.0132
TyrosinaseHomo sapiens (human)5
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)5.4
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2Homo sapiens (human)7
Glycogen synthase kinase-3 betaRattus norvegicus (Norway rat)0.066
Amine oxidase [flavin-containing] AHomo sapiens (human)3.5
Heme oxygenase 2Rattus norvegicus (Norway rat)10
Alpha-1D adrenergic receptorRattus norvegicus (Norway rat)5.4
Amine oxidase [flavin-containing] BHomo sapiens (human)2.5733
Proteasome subunit beta type-5Homo sapiens (human)10
17-beta-hydroxysteroid dehydrogenase type 2Homo sapiens (human)1.73
Alpha-synucleinHomo sapiens (human)0.22
Alpha-1A adrenergic receptorRattus norvegicus (Norway rat)5.4
10 kDa heat shock protein, mitochondrialHomo sapiens (human)8.3
Histone acetyltransferase p300Homo sapiens (human)6.5
60 kDa chaperonin Escherichia coli3
10 kDa chaperonin Escherichia coli3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3Homo sapiens (human)7
Cysteine protease Trypanosoma brucei rhodesiense7.75
CDGSH iron-sulfur domain-containing protein 1Homo sapiens (human)2.36
Broad substrate specificity ATP-binding cassette transporter ABCG2Homo sapiens (human)1.63
Beta lactamase (plasmid)Pseudomonas aeruginosa7.751

Research

Studies (35)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's21 (60.00)24.3611
2020's14 (40.00)2.80

Authors

AuthorsStudies
Arya, GC; Jaitak, V; Kaur, K1
Abrial, C; Barthomeuf, C; Bayet-Robert, M; Chollet, P; Durando, X; Gachon, F; Kwiatkowski, F; Leheurteur, M; Mouret-Reynier, MA; Planchat, E1
Choi, HG; Kim, DH; Sung, JH; Yan, YD; Yong, CS1
Dai, X; Guo, R; Hou, Z; Xu, H; Xu, Y; Yin, H; Zhang, Z; Zheng, D; Zheng, Y1
Choi, HG; Choi, YK; Kim, JO; Marasini, N; Woo, JS; Yan, YD; Yong, CS1
Bayet-Robert, M; Morvan, D1
Abd Elmageed, ZY; Abdel-Mageed, AB; Kostochka, ML; Liu, X; Mathur, A; Mondal, D; Zhang, H1
Liu, S; Tian, C; Wang, H; Wang, Y; Yan, J; Zhang, X1
Pawar, H; Suresh, S; Wankhade, SR; Yadav, DK1
Gu, D; Hu, L; Hu, Q; Kong, D; Pang, S; Su, J; Xiong, X1
Abrial, C; Atger, M; Bayet-Robert, M; Chollet, P; Curé, H; Durando, X; Eymard, JC; Gadea, E; Guy, L; Mahammedi, H; Planchat, E; Pouget, M; Savareux, L; Thivat, E; Van-Praagh, I1
Burman, R; Gill, MS; Pawar, H; Singh, C; Surapaneni, SK; Suresh, S; Tikoo, K1
Geetha, P; Gopi Mohan, C; Jayakumar, R; Sivaram, AJ1
Baishya, R; Bharadwaj, R; Das, MK; Dash, S; Hazarika, H; Loying, P; Sahu, BP1
Deng, J; Fan, R; Gao, X; Guo, G; Li, X; Tong, A; You, C; Zhang, X; Zheng, Y; Zhou, L1
Chen, X; Guo, C; Li, J; Qiu, Z; Sun, X; Wen, Y; Xing, H; Xu, J; Zhang, Q; Zhao, D; Zheng, Y1
Jia, Y; Liu, S; Liu, X; Pan, W; Tian, C; Wang, H; Wang, Y; Yan, J1
Banerjee, S; Chowdhury, I; Lillard, JW; Singh, R; Singh, SK1
Choi, HG; Hong, SS; Kim, JH; Kim, JK; Kim, JO; Kim, SY; Lim, SJ; Thapa, RK1
Chang, C; Chou, F; Lin, C; Luo, J; Niu, Y; Tian, J; Xing, EZ; Yeh, S; Zuo, L1
An, Q; Guo, H; Liu, YN; Liu, ZH; Niu, FJ; Shi, CX; Xie, SM; Yang, YY; Zhou, CZ1
Ates, H; Cengiz, H; Kocdor, H; Kocdor, MA1
Cao, QR; Cui, JH; Lee, BJ; Loebenberg, R; Meghani, N; Park, C1
Gao, S; Li, J; Liu, B; Tang, M; Wang, Z; Zhang, L; Zhang, W1
Abdul Rahman, MB; Abdulmalek, E; Asmawi, AA; Salim, N1
Patel, B; Patel, MM; Rawal, S1
Bu, LP; Li, XY; Liu, H; Liu, P; Shao, L; Ying, Q; Yu, SQ1
Deng, L; Feng, L; Guo, R; Li, Y; Liu, Z; Qin, L; Yu, Z; Zheng, Y; Zhu, X1
Cheng, Y; Hu, Y; Lin, Y; Ran, M; Wang, B; Zheng, S1
Abrial, C; Atger, M; Chollet, P; Durando, X; Eymard, JC; Ginzac Couvé, A; Kwiatkowski, F; Mahammedi, H; Monange, B; Passildas-Jahanmohan, J; Pouget, M; Richard, D; Savareux, L; Thivat, E; Van Praagh, I1
Deng, L; Fang, Z; Feng, L; Guo, R; Li, Y; Liu, Z; Qin, L; Wu, X; Yu, Z; Zheng, Y; Zhu, X1
Tong, L; Wang, G; Wu, C; Zhou, Z1
Bensa, V; Celia, C; Cilli, M; Decuzzi, P; Di Francesco, M; Di Francesco, V; Di Marzio, L; Ferreira, M; Fragassi, A; Palange, AL; Pastorino, F; Ponzoni, M1
Hu, J; Liu, J; Sun, L; Yao, X; Zhang, Y1
Angiolini, V; Bei, R; Benvenuto, M; Di Meo, C; Frajese, GV; Mancini, P; Masuelli, L; Matricardi, P; Nalli, M; Nardozi, D; Paoletti, L; Zoratto, N1

Reviews

1 review(s) available for docetaxel anhydrous and curcumin

ArticleYear
Isoxazole derivatives as anticancer agent: A review on synthetic strategies, mechanism of action and SAR studies.
    European journal of medicinal chemistry, 2021, Oct-05, Volume: 221

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Proliferation; Drug Screening Assays, Antitumor; Female; Humans; Isoxazoles

2021

Trials

3 trial(s) available for docetaxel anhydrous and curcumin

ArticleYear
Phase I dose escalation trial of docetaxel plus curcumin in patients with advanced and metastatic breast cancer.
    Cancer biology & therapy, 2010, Volume: 9, Issue:1

    Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Breast Neoplasms, Male; Carcinoma; Curcumin; Diarrhea; Docetaxel; Dose-Response Relationship, Drug; Drug Administration Schedule; Feasibility Studies; Female; Follow-Up Studies; Humans; Leukopenia; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Metastasis; Neutropenia; Taxoids; Time Factors; Treatment Outcome

2010
The New Combination Docetaxel, Prednisone and Curcumin in Patients with Castration-Resistant Prostate Cancer: A Pilot Phase II Study.
    Oncology, 2016, Volume: 90, Issue:2

    Topics: Adenocarcinoma; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Chromogranin A; Curcumin; Docetaxel; Geriatric Assessment; Humans; Male; Medication Adherence; Middle Aged; Phosphopyruvate Hydratase; Pilot Projects; Prednisone; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Survival Rate; Taxoids; Treatment Outcome

2016
Multicenter randomized phase II study comparing docetaxel plus curcumin versus docetaxel plus placebo in first-line treatment of metastatic castration-resistant prostate cancer.
    Cancer medicine, 2021, Volume: 10, Issue:7

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Curcumin; Disease Progression; Docetaxel; Double-Blind Method; Drug Administration Schedule; Early Termination of Clinical Trials; Humans; Male; Medical Futility; Medication Adherence; Middle Aged; Placebos; Progression-Free Survival; Prostate-Specific Antigen; Prostatic Neoplasms, Castration-Resistant; Quality of Life

2021

Other Studies

31 other study(ies) available for docetaxel anhydrous and curcumin

ArticleYear
Enhanced oral bioavailability of docetaxel in rats by four consecutive days of pre-treatment with curcumin.
    International journal of pharmaceutics, 2010, Oct-31, Volume: 399, Issue:1-2

    Topics: Administration, Oral; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Chromatography, High Pressure Liquid; Curcumin; Cytochrome P-450 CYP3A Inhibitors; Docetaxel; Dose-Response Relationship, Drug; Enzyme Inhibitors; Injections, Intravenous; Male; Rats; Rats, Sprague-Dawley; Substrate Specificity; Taxoids

2010
Synergistic antitumor efficiency of docetaxel and curcumin against lung cancer.
    Acta biochimica et biophysica Sinica, 2012, Volume: 44, Issue:2

    Topics: Animals; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Curcumin; Docetaxel; Drug Synergism; Female; Humans; Lung Neoplasms; Male; Medicine, Chinese Traditional; Mice; Mice, Nude; Taxoids; Xenograft Model Antitumor Assays

2012
Effect of dose and dosage interval on the oral bioavailability of docetaxel in combination with a curcumin self-emulsifying drug delivery system (SEDDS).
    European journal of drug metabolism and pharmacokinetics, 2012, Volume: 37, Issue:3

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Area Under Curve; Biological Availability; Curcumin; Docetaxel; Drug Delivery Systems; Emulsions; Male; Rats; Rats, Sprague-Dawley; Taxoids

2012
Metabolomics reveals metabolic targets and biphasic responses in breast cancer cells treated by curcumin alone and in association with docetaxel.
    PloS one, 2013, Volume: 8, Issue:3

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Comet Assay; Curcumin; Docetaxel; Female; Glutathione; Glutathione Transferase; Humans; Inflammation; Magnetic Resonance Spectroscopy; MCF-7 Cells; Metabolomics; Multivariate Analysis; Oxidative Stress; Taxoids; Treatment Outcome

2013
Subverting ER-stress towards apoptosis by nelfinavir and curcumin coexposure augments docetaxel efficacy in castration resistant prostate cancer cells.
    PloS one, 2014, Volume: 9, Issue:8

    Topics: Animals; Apoptosis; Cell Line, Tumor; Curcumin; Docetaxel; Endoplasmic Reticulum Stress; Epithelial Cells; Humans; Male; Mice; Mice, Nude; Nelfinavir; Phosphatidylinositol 3-Kinases; Prostatic Neoplasms, Castration-Resistant; Proto-Oncogene Proteins c-akt; Taxoids; Thapsigargin

2014
Targeted nanomedicine for prostate cancer therapy: docetaxel and curcumin co-encapsulated lipid-polymer hybrid nanoparticles for the enhanced anti-tumor activity in vitro and in vivo.
    Drug delivery, 2016, Volume: 23, Issue:5

    Topics: Animals; Cell Line, Tumor; Curcumin; Docetaxel; Drug Carriers; Drug Delivery Systems; Heterografts; Humans; Lipids; Male; Mice; Nanomedicine; Particle Size; Polymers; Prostatic Neoplasms; Taxoids

2016
Development and evaluation of co-formulated docetaxel and curcumin biodegradable nanoparticles for parenteral administration.
    Pharmaceutical development and technology, 2016, Volume: 21, Issue:6

    Topics: Animals; Antineoplastic Agents; Chemistry, Pharmaceutical; Curcumin; Docetaxel; Drug Carriers; Drug Evaluation, Preclinical; Female; Humans; Infusions, Parenteral; Male; MCF-7 Cells; Nanoparticles; Random Allocation; Rats; Rats, Wistar; Taxoids

2016
Enhanced antitumor efficacy of folate targeted nanoparticles co-loaded with docetaxel and curcumin.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2015, Volume: 75

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Proliferation; Cell Survival; Chemistry, Pharmaceutical; Curcumin; Docetaxel; Drug Carriers; Folic Acid; HeLa Cells; Humans; Lung Neoplasms; Mice, Inbred C57BL; Nanomedicine; Nanoparticles; Polyesters; Polyethylene Glycols; Sarcoma 180; Solubility; Taxoids; Time Factors; Tumor Burden

2015
Folic acid functionalized long-circulating co-encapsulated docetaxel and curcumin solid lipid nanoparticles: In vitro evaluation, pharmacokinetic and biodistribution in rats.
    Drug delivery, 2016, Volume: 23, Issue:4

    Topics: Animals; Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Chemistry, Pharmaceutical; Curcumin; Docetaxel; Drug Carriers; Drug Liberation; Female; Folic Acid; Humans; Lipids; MCF-7 Cells; Nanoparticles; Rats; Rats, Wistar; Taxoids; Tissue Distribution

2016
Integration of in silico modeling, prediction by binding energy and experimental approach to study the amorphous chitin nanocarriers for cancer drug delivery.
    Carbohydrate polymers, 2016, May-20, Volume: 142

    Topics: Adenocarcinoma; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Chitin; Curcumin; Docetaxel; Drug Carriers; Fluorouracil; Humans; Molecular Docking Simulation; Nanoparticles; Stomach; Stomach Neoplasms; Taxoids; Thermodynamics

2016
Curcumin-docetaxel co-loaded nanosuspension for enhanced anti-breast cancer activity.
    Expert opinion on drug delivery, 2016, Volume: 13, Issue:8

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Availability; Breast Neoplasms; Curcumin; Docetaxel; Female; Humans; Male; MCF-7 Cells; Mice; Nanoparticles; Particle Size; Solubility; Suspensions; Taxoids; Tissue Distribution

2016
Dual Drug Loaded Biodegradable Nanofibrous Microsphere for Improving Anti-Colon Cancer Activity.
    Scientific reports, 2016, 06-21, Volume: 6

    Topics: Abdominal Neoplasms; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Colonic Neoplasms; Curcumin; Docetaxel; Drug Carriers; Drug Screening Assays, Antitumor; Flow Cytometry; Hemolysis; Humans; Magnetic Resonance Spectroscopy; Mice; Mice, Inbred BALB C; Microspheres; Molecular Weight; Nanofibers; Nanoparticles; Neoplasm Metastasis; Poloxamer; Polymers; Spectroscopy, Fourier Transform Infrared; Taxoids; Thermogravimetry; X-Ray Diffraction

2016
Pharmacokinetic effects of curcumin on docetaxel mediated by OATP1B1, OATP1B3 and CYP450s.
    Drug metabolism and pharmacokinetics, 2016, Volume: 31, Issue:4

    Topics: Animals; Antineoplastic Agents; Curcumin; Docetaxel; Drug Interactions; HEK293 Cells; Humans; Kinetics; Liver-Specific Organic Anion Transporter 1; Male; Microsomes, Liver; Organic Anion Transporters, Sodium-Independent; Rats, Sprague-Dawley; Taxoids

2016
Co-delivery of docetaxel and curcumin prodrug via dual-targeted nanoparticles with synergistic antitumor activity against prostate cancer.
    Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Volume: 88

    Topics: Aconitic Acid; Animals; Antineoplastic Agents; Cell Death; Cell Line, Tumor; Coumarins; Curcumin; Docetaxel; Drug Delivery Systems; Drug Liberation; Drug Stability; Drug Synergism; Endocytosis; Humans; Inhibitory Concentration 50; Lactic Acid; Male; Mice, Inbred BALB C; Mice, Nude; Nanoparticles; Particle Size; Peptides; Polyethylene Glycols; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Prodrugs; Prostatic Neoplasms; Proton Magnetic Resonance Spectroscopy; Taxoids; Thiazoles

2017
Combinatorial effect of curcumin with docetaxel modulates apoptotic and cell survival molecules in prostate cancer.
    Frontiers in bioscience (Elite edition), 2017, 03-01, Volume: 9, Issue:2

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biomarkers, Tumor; Cell Line, Tumor; Cell Proliferation; Curcumin; Docetaxel; Humans; Male; Prostatic Neoplasms; Taxoids

2017
Role of zein incorporation on hydrophobic drug-loading capacity and colloidal stability of phospholipid nanoparticles.
    Colloids and surfaces. B, Biointerfaces, 2018, Nov-01, Volume: 171

    Topics: Celecoxib; Colloids; Curcumin; Docetaxel; Drug Carriers; Hydrophobic and Hydrophilic Interactions; Nanoparticles; Paclitaxel; Particle Size; Phospholipids; Surface Properties; Zein

2018
Targeting the androgen receptor (AR) with AR degradation enhancer ASC-J9® led to increase docetaxel sensitivity via suppressing the p21 expression.
    Cancer letters, 2019, 03-01, Volume: 444

    Topics: Antineoplastic Agents; Apoptosis; Cell Proliferation; Curcumin; Cyclin-Dependent Kinase Inhibitor p21; Docetaxel; Drug Resistance, Neoplasm; Drug Synergism; Gene Expression Regulation, Neoplastic; Humans; Male; Prostatic Neoplasms; Proteolysis; Receptors, Androgen; Tumor Cells, Cultured

2019
Development and characterization of octreotide-modified curcumin plus docetaxel micelles for potential treatment of non-small-cell lung cancer.
    Pharmaceutical development and technology, 2019, Volume: 24, Issue:9

    Topics: A549 Cells; Animals; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Curcumin; Docetaxel; Drug Carriers; Drug Delivery Systems; Humans; Lung Neoplasms; Mice, Inbred BALB C; Mice, Nude; Micelles; Octreotide; Polyethylene Glycols; Polyvinyls

2019
Inhibition of Cancer Stem-Like Phenotype by Curcumin and Deguelin in CAL-62 Anaplastic Thyroid Cancer Cells.
    Anti-cancer agents in medicinal chemistry, 2019, Volume: 19, Issue:15

    Topics: AC133 Antigen; Apoptosis; Cell Cycle; Cell Line, Tumor; Curcumin; Docetaxel; Drug Therapy, Combination; Humans; Nanog Homeobox Protein; Neoplastic Stem Cells; Octamer Transcription Factors; Oxidative Stress; Phenotype; Rotenone; Superoxide Dismutase; Thy-1 Antigens; Thyroid Carcinoma, Anaplastic; Thyroid Neoplasms

2019
Fatty acid chain length impacts nanonizing capacity of albumin-fatty acid nanomicelles: Enhanced physicochemical property and cellular delivery of poorly water-soluble drug.
    European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V, 2020, Volume: 152

    Topics: A549 Cells; Albumins; Cell Line; Cell Line, Tumor; Curcumin; Docetaxel; Drug Carriers; Drug Liberation; Fatty Acids; HEK293 Cells; Humans; MCF-7 Cells; Micelles; Nanoparticles; Nanotechnology; Particle Size; Solubility; Water

2020
Docetaxel suppresses immunotherapy efficacy of natural killer cells toward castration-resistant prostate cancer cells via altering androgen receptor-lectin-like transcript 1 signals.
    The Prostate, 2020, Volume: 80, Issue:10

    Topics: Androgen Receptor Antagonists; Antibodies, Monoclonal; Antineoplastic Agents; Cell Line, Tumor; Coculture Techniques; Combined Modality Therapy; Curcumin; Docetaxel; HEK293 Cells; Humans; Immunotherapy, Adoptive; Killer Cells, Natural; Lectins, C-Type; Male; Prostatic Neoplasms, Castration-Resistant; Receptors, Androgen; Receptors, Cell Surface; Up-Regulation

2020
Modeling the Effect of Composition on Formation of Aerosolized Nanoemulsion System Encapsulating Docetaxel and Curcumin Using D-Optimal Mixture Experimental Design.
    International journal of molecular sciences, 2020, Jun-19, Volume: 21, Issue:12

    Topics: Aerosols; Antineoplastic Agents; Capsules; Curcumin; Docetaxel; Drug Compounding; Emulsions; Humans; Models, Theoretical; Nanoparticles; Particle Size; Solubility

2020
Fabrication, optimisation and
    Journal of microencapsulation, 2020, Volume: 37, Issue:8

    Topics: Antineoplastic Agents; Calorimetry, Differential Scanning; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Survival; Cobalt; Curcumin; Docetaxel; Drug Delivery Systems; Drug Screening Assays, Antitumor; Hemolysis; Humans; Hydrogen-Ion Concentration; In Vitro Techniques; Lipids; Lung Neoplasms; Microspheres; Nanostructures; Particle Size; Temperature; Tetrazolium Salts; Thiazoles; X-Ray Diffraction

2020
Curcumin enhances anti‑cancer efficacy of either gemcitabine or docetaxel on pancreatic cancer cells.
    Oncology reports, 2020, Volume: 44, Issue:4

    Topics: Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Cadherins; Caspase 3; Cell Line, Tumor; Cell Proliferation; Cell Survival; Curcuma; Curcumin; Deoxycytidine; Docetaxel; Drug Synergism; Gemcitabine; Gene Expression Regulation, Neoplastic; Humans; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Pancreatic Neoplasms; Plant Extracts; Poly (ADP-Ribose) Polymerase-1; Tissue Inhibitor of Metalloproteinase-1; Tissue Inhibitor of Metalloproteinase-2

2020
Novel T7-Modified pH-Responsive Targeted Nanosystem for Co-Delivery of Docetaxel and Curcumin in the Treatment of Esophageal Cancer.
    International journal of nanomedicine, 2020, Volume: 15

    Topics: Animals; Antineoplastic Agents; Curcumin; Docetaxel; Drug Carriers; Drug Liberation; Esophageal Neoplasms; Humans; Hydrogen-Ion Concentration; Nanomedicine; Nanoparticles; Polyethylene Glycols; Polyethyleneimine; Tumor Microenvironment

2020
Co-Delivery of Docetaxel and Curcumin via Nanomicelles for Enhancing Anti-Ovarian Cancer Treatment.
    International journal of nanomedicine, 2020, Volume: 15

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Curcumin; Docetaxel; Drug Carriers; Drug Liberation; Female; Humans; Lactates; Micelles; Ovarian Neoplasms; Polyethylene Glycols

2020
Chitosan-based nanoparticle co-delivery of docetaxel and curcumin ameliorates anti-tumor chemoimmunotherapy in lung cancer.
    Carbohydrate polymers, 2021, Sep-15, Volume: 268

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Chitosan; Curcumin; Docetaxel; Drug Carriers; Drug Liberation; Humans; Hydrogen-Ion Concentration; Lung; Lung Neoplasms; Lymphocytes, Tumor-Infiltrating; Macrophages; Mice; Myeloid-Derived Suppressor Cells; Nanoparticles; Reactive Oxygen Species; T-Lymphocytes; Tumor Microenvironment; Xenograft Model Antitumor Assays

2021
A self-microemulsion enhances oral absorption of docetaxel by inhibiting P-glycoprotein and CYP metabolism.
    Drug delivery and translational research, 2023, Volume: 13, Issue:4

    Topics: Administration, Oral; ATP Binding Cassette Transporter, Subfamily B; Biological Availability; Curcumin; Cytochrome P-450 Enzyme System; Docetaxel

2023
Augmented efficacy of nano-formulated docetaxel plus curcumin in orthotopic models of neuroblastoma.
    Pharmacological research, 2023, Volume: 188

    Topics: Animals; Antineoplastic Agents; Cell Line, Tumor; Child; Curcumin; Docetaxel; Humans; Mice; Nanoparticles; Neuroblastoma; Polymers

2023
Curcumin Enhances the Efficacy of Docetaxel by Promoting Anti-Tumor Immune Response in Head and Neck Squamous Cell Carcinoma.
    Cancer investigation, 2023, Volume: 41, Issue:5

    Topics: Animals; CD8-Positive T-Lymphocytes; Curcumin; Docetaxel; Head and Neck Neoplasms; Humans; Immunity; Squamous Cell Carcinoma of Head and Neck; Tumor Microenvironment

2023
Hyaluronan-estradiol nanogels as potential drug carriers to target ER+ breast cancer cell line.
    Carbohydrate polymers, 2023, Aug-15, Volume: 314

    Topics: Antineoplastic Agents; Breast Neoplasms; Cell Line, Tumor; Curcumin; Docetaxel; Drug Carriers; Drug Delivery Systems; Estradiol; Female; Humans; Hyaluronic Acid; MCF-7 Cells; Nanogels; Nanoparticles

2023