Page last updated: 2024-09-04

docetaxel anhydrous and colchicine

docetaxel anhydrous has been researched along with colchicine in 18 studies

Compound Research Comparison

Studies
(docetaxel anhydrous)
Trials
(docetaxel anhydrous)
Recent Studies (post-2010)
(docetaxel anhydrous)
Studies
(colchicine)
Trials
(colchicine)
Recent Studies (post-2010) (colchicine)
12,1103,2166,92015,4724042,974

Protein Interaction Comparison

ProteinTaxonomydocetaxel anhydrous (IC50)colchicine (IC50)
Tubulin alpha-1A chainSus scrofa (pig)3.7639
Tubulin beta chainSus scrofa (pig)3.8663
Tubulin beta-4A chainHomo sapiens (human)2.4334
Tubulin beta chainHomo sapiens (human)2.7244
Tubulin alpha-3C chainHomo sapiens (human)2.4334
Serine/threonine-protein kinase pim-1Homo sapiens (human)4.3
Tubulin alpha-1B chainHomo sapiens (human)2.4334
Tubulin alpha-4A chainHomo sapiens (human)2.4334
Tubulin beta-4B chainHomo sapiens (human)2.4334
Vesicular acetylcholine transporterTetronarce californica (Pacific electric ray)2.62
Tubulin beta-3 chainHomo sapiens (human)2.4334
Tubulin beta-2A chainHomo sapiens (human)2.4334
Tubulin beta-8 chainHomo sapiens (human)2.4334
Tubulin beta-2B chainBos taurus (cattle)2.8255
Tubulin alpha-3E chainHomo sapiens (human)2.4334
Tubulin alpha-1A chainHomo sapiens (human)2.4334
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)3.0611
Similar to alpha-tubulin isoform 1 Bos taurus (cattle)3.1553
Tubulin alpha-1C chainHomo sapiens (human)2.4334
Tubulin beta-6 chainHomo sapiens (human)2.4334
Tubulin beta-2B chainHomo sapiens (human)2.4334
Tubulin beta-1 chainHomo sapiens (human)2.4334

Research

Studies (18)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.56)18.2507
2000's4 (22.22)29.6817
2010's11 (61.11)24.3611
2020's2 (11.11)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Capuano, B; DeBono, A; Scammells, PJ1
Brett, ML; Colley, HE; Coole, SF; Danson, SJ; Dossetter, AG; Griffen, EJ; Harrison, J; Jackson, LV; Jennings, LR; Lockey, PM; Mason, DP; Muthana, M; Norman, D; Thompson, MJ; Tulasi, V; Williams, L; Wong, M1
Bougeret, C; Guillou, C; Kozielski, F; Labrière, C; Talapatra, SK; Thoret, S1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Arnst, KE; Banerjee, S; Deng, S; Kumar, G; Li, GB; Li, W; Miller, DD; Wang, Y; White, SW; Yang, J; Yang, L1
Arya, GC; Jaitak, V; Kaur, K1
Braguer, D; Briand, C; Carles, G; Garcia, P1
Arné-Bès, MC1
Borsotti, P; Dossi, R; Fiordaliso, F; Giavazzi, R; Martinelli, M; Micheletti, G; Ryan, AJ; Taraboletti, G1
Escuin, D; Giannakakou, P; Kline, ER1
Brock, M; Canto, MI; Daniels, JA; Gibson, MK; Heath, E; Montgomery, E; Sun, S; Wang, J; Xu, L1
Ahn, S; Dalton, JT; Li, CM; Lu, Y; Miller, DD; Narayanan, R1
Kang, HS; Kim, JH; Ro, J; Yoo, HI; Yoon, S1
Ahn, S; Chen, J; Costello, TA; Dalton, JT; Dalton, MN; Li, CM; Li, W; Lu, Y; Miller, DD; Narayanan, R; Snyder, LM1
Dong, H; Sun, H; Zheng, J1
Brindley, DN; Chen, X; Joy, AA; Parissenti, AM; Tuszynski, J; Wang, RC; Wang, Z1
Jurášek, M; Rimpelová, S; Ruml, T; Škubník, J1

Reviews

4 review(s) available for docetaxel anhydrous and colchicine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Isoxazole derivatives as anticancer agent: A review on synthetic strategies, mechanism of action and SAR studies.
    European journal of medicinal chemistry, 2021, Oct-05, Volume: 221

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Cell Proliferation; Drug Screening Assays, Antitumor; Female; Humans; Isoxazoles

2021
[Neurotoxic effects of medications: an update].
    Revue medicale de Liege, 2004, Volume: 59 Suppl 1

    Topics: Anti-Retroviral Agents; Antineoplastic Agents; Carboplatin; Cisplatin; Colchicine; Docetaxel; Humans; Interferon-alpha; Neurotoxicity Syndromes; Organoplatinum Compounds; Oxaliplatin; Paclitaxel; Peripheral Nervous System Diseases; Taxoids; Thalidomide

2004
Mitotic Poisons in Research and Medicine.
    Molecules (Basel, Switzerland), 2020, Oct-12, Volume: 25, Issue:20

    Topics: Animals; Antineoplastic Agents; Colchicine; Docetaxel; Humans; Mitosis; Paclitaxel

2020

Other Studies

14 other study(ies) available for docetaxel anhydrous and colchicine

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Progress Toward the Development of Noscapine and Derivatives as Anticancer Agents.
    Journal of medicinal chemistry, 2015, Aug-13, Volume: 58, Issue:15

    Topics: Antineoplastic Agents; Cell Line, Tumor; Drug Screening Assays, Antitumor; Humans; Neoplasms; Noscapine

2015
An Orally Bioavailable, Indole-3-glyoxylamide Based Series of Tubulin Polymerization Inhibitors Showing Tumor Growth Inhibition in a Mouse Xenograft Model of Head and Neck Cancer.
    Journal of medicinal chemistry, 2015, Dec-10, Volume: 58, Issue:23

    Topics: Animals; Antineoplastic Agents; Caco-2 Cells; Cell Proliferation; Drug Screening Assays, Antitumor; Head and Neck Neoplasms; Heterografts; Humans; Indoles; Male; Mice; Mice, Nude; Microtubules; Neoplasm Transplantation; Structure-Activity Relationship; Tubulin; Tubulin Modulators

2015
New MKLP-2 inhibitors in the paprotrain series: Design, synthesis and biological evaluations.
    Bioorganic & medicinal chemistry, 2016, Feb-15, Volume: 24, Issue:4

    Topics: Acrylonitrile; Animals; Antimitotic Agents; Brain Chemistry; Cell Line, Tumor; Cytokinesis; Drug Design; Epithelial Cells; Gene Expression; Humans; Indoles; Kinesins; Microtubules; Sheep; Structure-Activity Relationship

2016
Heterocyclic-Fused Pyrimidines as Novel Tubulin Polymerization Inhibitors Targeting the Colchicine Binding Site: Structural Basis and Antitumor Efficacy.
    Journal of medicinal chemistry, 2018, 02-22, Volume: 61, Issue:4

    Topics: Animals; Apoptosis; Binding Sites; Colchicine; Crystallography, X-Ray; Drug Design; Drug Resistance, Multiple; Heterografts; Humans; Male; Melanoma; Polymerization; Prostatic Neoplasms; Pyrimidines; Tubulin

2018
Simultaneous combination of microtubule depolymerizing and stabilizing agents acts at low doses.
    Anti-cancer drugs, 1995, Volume: 6, Issue:4

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carbamates; Cell Division; Colchicine; Demecolcine; Docetaxel; Humans; KB Cells; Microscopy, Fluorescence; Microscopy, Immunoelectron; Microtubule Proteins; Microtubules; Paclitaxel; Pyrazines; Pyridines; Taxoids; Tubulin

1995
Potential antagonism of tubulin-binding anticancer agents in combination therapies.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 2005, Apr-01, Volume: 11, Issue:7

    Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Adhesion; Cell Line; Cell Line, Tumor; Cell Proliferation; Cisplatin; Colchicine; Cytoskeleton; Docetaxel; Dose-Response Relationship, Drug; Doxorubicin; Drug Interactions; Endothelial Cells; Female; Humans; Mice; Mice, Inbred C57BL; Mice, Nude; Microscopy, Fluorescence; Necrosis; Organophosphorus Compounds; Paclitaxel; Protein Binding; Taxoids; Tubulin; Umbilical Veins; Vincristine; Xenograft Model Antitumor Assays

2005
Both microtubule-stabilizing and microtubule-destabilizing drugs inhibit hypoxia-inducible factor-1alpha accumulation and activity by disrupting microtubule function.
    Cancer research, 2005, Oct-01, Volume: 65, Issue:19

    Topics: 2-Methoxyestradiol; Alkaloids; Alkanes; Antineoplastic Agents; Carbamates; Cell Line, Tumor; Colchicine; Docetaxel; Down-Regulation; Epothilones; Estradiol; Humans; Hypoxia-Inducible Factor 1, alpha Subunit; Lactones; Microtubules; Pyrones; Taxoids; Vincristine

2005
Gastrointestinal tract epithelial changes associated with taxanes: marker of drug toxicity versus effect.
    The American journal of surgical pathology, 2008, Volume: 32, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Colchicine; Docetaxel; Epithelium; Esophagus; Female; Gastric Mucosa; Humans; Intestinal Mucosa; Male; Middle Aged; Mitosis; Paclitaxel; Taxoids

2008
Competitive mass spectrometry binding assay for characterization of three binding sites of tubulin.
    Journal of mass spectrometry : JMS, 2010, Volume: 45, Issue:10

    Topics: Animals; Binding Sites; Binding, Competitive; Cattle; Chromatography, Liquid; Colchicine; Docetaxel; Guanosine Triphosphate; Linear Models; Paclitaxel; Podophyllotoxin; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Taxoids; Thiazoles; Tubulin; Tubulin Modulators; Vinblastine; Vincristine

2010
Salinomycin sensitizes antimitotic drugs-treated cancer cells by increasing apoptosis via the prevention of G2 arrest.
    Biochemical and biophysical research communications, 2012, Feb-03, Volume: 418, Issue:1

    Topics: Antimitotic Agents; Apoptosis; Cell Line, Tumor; Colchicine; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; DNA Damage; Docetaxel; Drug Resistance, Neoplasm; G2 Phase Cell Cycle Checkpoints; Humans; Paclitaxel; Pyrans; Taxoids; Vinblastine

2012
Orally bioavailable tubulin antagonists for paclitaxel-refractory cancer.
    Pharmaceutical research, 2012, Volume: 29, Issue:11

    Topics: Animals; Antineoplastic Agents; Apoptosis; ATP Binding Cassette Transporter, Subfamily B; Binding Sites; Biological Availability; Caco-2 Cells; Cell Line, Tumor; Colchicine; Docetaxel; Dogs; Drug Interactions; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Indoles; Male; Mice; Mice, Inbred ICR; Mice, Nude; Neoplasms; Paclitaxel; Polymerization; Rats; Rats, Sprague-Dawley; Taxoids; Tubulin; Tubulin Modulators

2012
A microchip for integrated single-cell genotoxicity assay.
    Talanta, 2016, Dec-01, Volume: 161

    Topics: Aurora Kinase A; Colchicine; Cyclin-Dependent Kinase Inhibitor p21; Docetaxel; Gene Expression Profiling; Glyceraldehyde-3-Phosphate Dehydrogenases; Humans; Lab-On-A-Chip Devices; MCF-7 Cells; Methyl Methanesulfonate; Microfluidics; Mutagenicity Tests; Real-Time Polymerase Chain Reaction; Taxoids

2016
Sensitivity of docetaxel-resistant MCF-7 breast cancer cells to microtubule-destabilizing agents including vinca alkaloids and colchicine-site binding agents.
    PloS one, 2017, Volume: 12, Issue:8

    Topics: Antineoplastic Agents; Apoptosis; Breast Neoplasms; Bridged-Ring Compounds; Chromatin; Colchicine; Docetaxel; Drug Resistance, Neoplasm; Humans; MCF-7 Cells; Microtubules; Taxoids; Vinca Alkaloids

2017