Page last updated: 2024-09-04

docetaxel anhydrous and chloroquine

docetaxel anhydrous has been researched along with chloroquine in 10 studies

Compound Research Comparison

Studies
(docetaxel anhydrous)
Trials
(docetaxel anhydrous)
Recent Studies (post-2010)
(docetaxel anhydrous)
Studies
(chloroquine)
Trials
(chloroquine)
Recent Studies (post-2010) (chloroquine)
12,1103,2166,92016,4057634,029

Protein Interaction Comparison

ProteinTaxonomydocetaxel anhydrous (IC50)chloroquine (IC50)
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonasePlasmodium berghei43
Spike glycoproteinBetacoronavirus England 15.47
Replicase polyprotein 1abBetacoronavirus England 15.47
Transmembrane protease serine 2Homo sapiens (human)5.47
Dihydrofolate reductase Bos taurus (cattle)0.0301
Amyloid-beta precursor proteinHomo sapiens (human)7
Histidine-rich protein PFHRP-IIPlasmodium falciparum (malaria parasite P. falciparum)0.2383
Procathepsin LHomo sapiens (human)5.47
Replicase polyprotein 1aSevere acute respiratory syndrome-related coronavirus5.47
Replicase polyprotein 1abHuman coronavirus 229E5.47
Replicase polyprotein 1abSevere acute respiratory syndrome-related coronavirus5.47
Spike glycoproteinSevere acute respiratory syndrome coronavirus 23.58
Replicase polyprotein 1abSevere acute respiratory syndrome coronavirus 26.375
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)1.5
Serine/threonine-protein kinase mTORHomo sapiens (human)0.27
Beta-secretase 1Homo sapiens (human)7
Spike glycoproteinSevere acute respiratory syndrome-related coronavirus5.47
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)2.503
Angiotensin-converting enzyme 2 Homo sapiens (human)6.235
Cysteine proteinase falcipain 2a Plasmodium falciparum (malaria parasite P. falciparum)0.02
Cysteine proteinase falcipain 2a Plasmodium falciparum (malaria parasite P. falciparum)0.2

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (70.00)24.3611
2020's3 (30.00)2.80

Authors

AuthorsStudies
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Armstrong, JL; Birch-Machin, MA; Ellis, R; Lovat, PE; McKee, C; Wright, TJ1
Chen, H; Feng, SS; Huang, L; Li, X; Liang, X; Mei, L; Yang, Y; Zeng, X; Zhang, X1
Chen, H; Huang, L; Liang, X; Liu, Z; Mei, L; Tao, W; Xiao, X; Yang, Y; Zeng, X; Zhang, X1
Luan, Y; Shi, C; Shi, J; Wang, F; Zhang, Z1
Choi, AR; Kim, HS; Kim, JH; Woo, YH; Yoon, S1
Hu, TT; Li, LN; Lin, JZ; Wang, WW; Wu, HF; Xu, Z; Yu, HB; Zhang, CY; Zhu, GY; Zhu, JG1
Giatromanolaki, A; Kakouratos, C; Karakasiliotis, I; Kassela, K; Koukourakis, MI; Lamprou, I; Mitrakas, AG; Tsolou, A; Xanthopoulou, ET; Zois, CE1
Huang, J; Lai, W; Li, G; Wang, F; Wang, J; Xie, D; Xu, R; Zhang, R; Zhou, M1

Reviews

1 review(s) available for docetaxel anhydrous and chloroquine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

9 other study(ies) available for docetaxel anhydrous and chloroquine

ArticleYear
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the therapeutic efficacy of docetaxel for cutaneous squamous cell carcinoma through the combined inhibition of phosphatidylinositol 3-kinase/AKT signalling and autophagy.
    Clinical and experimental dermatology, 2013, Volume: 38, Issue:4

    Topics: Analysis of Variance; Antimalarials; Antineoplastic Agents; Autophagy; Carcinoma, Squamous Cell; Chloroquine; Docetaxel; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Inhibitors; Humans; Phosphoinositide-3 Kinase Inhibitors; Signal Transduction; Skin Neoplasms; Taxoids; Tumor Cells, Cultured

2013
The chemotherapeutic potential of PEG-b-PLGA copolymer micelles that combine chloroquine as autophagy inhibitor and docetaxel as an anti-cancer drug.
    Biomaterials, 2014, Volume: 35, Issue:33

    Topics: Animals; Antineoplastic Agents; Autophagy; Cell Line, Tumor; Chloroquine; Docetaxel; Drug Delivery Systems; Female; Humans; MCF-7 Cells; Mice; Mice, SCID; Micelles; Nanomedicine; Nanoparticles; Particle Size; Polyethylene Glycols; Polyglactin 910; Taxoids

2014
Enhancing therapeutic effects of docetaxel-loaded dendritic copolymer nanoparticles by co-treatment with autophagy inhibitor on breast cancer.
    Theranostics, 2014, Volume: 4, Issue:11

    Topics: Animals; Antineoplastic Agents; Autophagy; Breast Neoplasms; Chloroquine; Dendrimers; Disease Models, Animal; Docetaxel; Drug Carriers; Female; Humans; Lysosomes; MCF-7 Cells; Mice, SCID; Nanoparticles; Phagosomes; Taxoids; Treatment Outcome

2014
Co-delivery of docetaxel and chloroquine via PEO-PPO-PCL/TPGS micelles for overcoming multidrug resistance.
    International journal of pharmaceutics, 2015, Nov-30, Volume: 495, Issue:2

    Topics: Antineoplastic Agents; Cell Death; Cell Line, Tumor; Chloroquine; Docetaxel; Drug Combinations; Drug Delivery Systems; Drug Liberation; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Synergism; Hemolysis; Humans; Micelles; Polyesters; Polyethylene Glycols; Taxoids; Vitamin E

2015
Anti-malarial Drugs Primaquine and Chloroquine Have Different Sensitization Effects with Anti-mitotic Drugs in Resistant Cancer Cells.
    Anticancer research, 2016, Volume: 36, Issue:4

    Topics: Antimalarials; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Chloroquine; Docetaxel; Drug Resistance, Neoplasm; Humans; Mitosis; Paclitaxel; Primaquine; Taxoids; Vinblastine; Vinorelbine

2016
FOXM1 contributes to docetaxel resistance in castration-resistant prostate cancer by inducing AMPK/mTOR-mediated autophagy.
    Cancer letters, 2020, 01-28, Volume: 469

    Topics: AMP-Activated Protein Kinase Kinases; Apoptosis; Autophagy; Autophagy-Related Protein 7; Beclin-1; Cell Line, Tumor; Cell Proliferation; Chloroquine; Docetaxel; Drug Resistance, Neoplasm; Forkhead Box Protein M1; Gene Expression Regulation, Neoplastic; Humans; Male; Prostatic Neoplasms, Castration-Resistant; Protein Kinases; TOR Serine-Threonine Kinases

2020
Suppressed PLIN3 frequently occurs in prostate cancer, promoting docetaxel resistance via intensified autophagy, an event reversed by chloroquine.
    Medical oncology (Northwood, London, England), 2021, Aug-19, Volume: 38, Issue:10

    Topics: Antineoplastic Agents; Autophagy; Cell Line, Tumor; Chloroquine; Docetaxel; Drug Resistance, Neoplasm; Gene Silencing; Humans; Male; Perilipin-3; Prostatic Neoplasms

2021
Autophagy responsive intra-intercellular delivery nanoparticles for effective deep solid tumor penetration.
    Journal of nanobiotechnology, 2022, Jun-25, Volume: 20, Issue:1

    Topics: Autophagy; Cell Line, Tumor; Chloroquine; Docetaxel; Drug Delivery Systems; Humans; Nanoparticles; Neoplasms; Tumor Microenvironment

2022