Page last updated: 2024-09-04

docetaxel anhydrous and bibw 2992

docetaxel anhydrous has been researched along with bibw 2992 in 14 studies

Compound Research Comparison

Studies
(docetaxel anhydrous)
Trials
(docetaxel anhydrous)
Recent Studies (post-2010)
(docetaxel anhydrous)
Studies
(bibw 2992)
Trials
(bibw 2992)
Recent Studies (post-2010) (bibw 2992)
12,1103,2166,9201,0441471,007

Protein Interaction Comparison

ProteinTaxonomydocetaxel anhydrous (IC50)bibw 2992 (IC50)
Epidermal growth factor receptorHomo sapiens (human)0.0361
Receptor tyrosine-protein kinase erbB-2Homo sapiens (human)0.0168
Cytochrome P450 1A2Homo sapiens (human)0.037
Cytochrome P450 2E1Homo sapiens (human)0.014
Cytochrome P450 2C8Homo sapiens (human)0.037
Receptor tyrosine-protein kinase erbB-3Homo sapiens (human)0.0007
Cytochrome P450 2C19Homo sapiens (human)0.037
Glutamate receptor ionotropic, NMDA 2BRattus norvegicus (Norway rat)0.0016
Receptor tyrosine-protein kinase erbB-4Homo sapiens (human)0.0024

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's12 (85.71)24.3611
2020's2 (14.29)2.80

Authors

AuthorsStudies
Awada, AH; Besse-Hammer, T; Dumez, H; Fleischer, F; Hendlisz, A; Piccart, M; Schöffski, P; Stopfer, P; Uttenreuther-Fischer, M; Wolter, P1
Gordon, MS; Marshall, J; Ould-Kaci, M; Shapiro, GI; Stopfer, P; Uttenreuther-Fischer, M1
Au, JS; Brown, C; Chu, da T; Gebski, V; Gralla, RJ; Hirsh, V; Ho, JC; Inoue, A; Lee, CK; Lee, SM; Osorio Sanchez, JA; Tan, EH; Thongprasert, S; Tsai, CM; Vu, VV; Yang, JC; Zaatar, A1
Asano, H; Hashida, S; Maki, Y; Miyoshi, S; Miyoshi, Y; Ohtsuka, T; Shien, K; Soh, J; Suzawa, K; Toyooka, S; Tsukuda, K; Watanabe, M; Yamamoto, H1
Asai, K; Hirata, K; Isa, S; Kawaguchi, T; Kimura, T; Kubo, A; Kudoh, S; Matsuura, K; Mitsuoka, S; Nakai, T; Oka, T; Sawa, K; Suzumura, T; Tanaka, H; Uji, M; Watanabe, T; Yoshimoto, N; Yoshimura, N1
Chuang, JC; Das, M; Diehn, M; Huang, J; Liang, Y; Neal, JW; Stehr, H; Wakelee, HA1
Altavilla, G; Bulotta, A; Gonzalez-Cao, M; Gregorc, V; Karachaliou, N; Lazzari, C; Rosell, R; Santarpia, M; Verlicchi, A1
Miyoshi, S; Namba, K; Sakaguchi, M; Sato, H; Shien, K; Soh, J; Suzawa, K; Takeda, T; Tomida, S; Torigoe, H; Toyooka, S; Tsukuda, K; Yamamoto, H; Yoshioka, T1
Egger, J; Hann, A; Hermann, PC; Keller, F; Nosalski, E; Seufferlein, T1
Bacay, A; Bakst, RL; Catalano, PJ; Chau, NG; Gupta, V; Haddad, RI; Hanna, GJ; Mahmood, U; Margalit, DN; McHugh, P; Misiukiewicz, KJ; Posner, M; Rabinowits, G; Rath, L; Rawal, B; Schoenfeld, JD; Tishler, RB1
Rodriguez, E; Santos, ES1
Igai, H; Kamiyoshihara, M; Matsuura, N; Numajiri, K; Ohsawa, F1

Reviews

5 review(s) available for docetaxel anhydrous and bibw 2992

ArticleYear
Impact of EGFR inhibitor in non-small cell lung cancer on progression-free and overall survival: a meta-analysis.
    Journal of the National Cancer Institute, 2013, May-01, Volume: 105, Issue:9

    Topics: Afatinib; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cisplatin; Deoxycytidine; Disease-Free Survival; Docetaxel; ErbB Receptors; Erlotinib Hydrochloride; Female; Gefitinib; Gemcitabine; Glutamates; Guanine; Humans; Lung Neoplasms; Male; Middle Aged; Mutation; Pemetrexed; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Quinazolines; Randomized Controlled Trials as Topic; Survival Analysis; Taxoids

2013
Epidermal growth factor receptor tyrosine kinase inhibitors in previously treated advanced non-small-cell lung cancer with wild-type EGFR.
    Expert opinion on pharmacotherapy, 2016, Volume: 17, Issue:2

    Topics: Afatinib; Antineoplastic Agents; Biomarkers, Pharmacological; Carcinoma, Non-Small-Cell Lung; Disease-Free Survival; Docetaxel; ErbB Receptors; Erlotinib Hydrochloride; Genotype; Humans; Lung Neoplasms; Protein Kinase Inhibitors; Quinazolines; Randomized Controlled Trials as Topic; Taxoids

2016
Second-line therapy of squamous non-small cell lung cancer: an evolving landscape.
    Expert review of respiratory medicine, 2017, Volume: 11, Issue:6

    Topics: Afatinib; Angiogenesis Inhibitors; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Squamous Cell; Docetaxel; Humans; Lung Neoplasms; Quinazolines; Radiation-Sensitizing Agents; Ramucirumab; Retreatment; Taxoids

2017
Chemotherapeutic agents eligible for prior dosing in pancreatic cancer patients requiring hemodialysis: a systematic review
.
    Clinical nephrology, 2018, Volume: 90, Issue:2

    Topics: Afatinib; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Camptothecin; Carcinoma, Pancreatic Ductal; Deoxycytidine; Docetaxel; Fluorouracil; Gemcitabine; Humans; Irinotecan; Kidney Failure, Chronic; Organoplatinum Compounds; Oxaliplatin; Pancreatic Neoplasms; Quinazolines; Renal Dialysis; Taxoids

2018
Treatment Considerations for Patients With Advanced Squamous Cell Carcinoma of the Lung.
    Clinical lung cancer, 2022, Volume: 23, Issue:6

    Topics: Afatinib; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Carcinoma, Squamous Cell; Docetaxel; Humans; Lung; Lung Neoplasms; Platinum

2022

Trials

3 trial(s) available for docetaxel anhydrous and bibw 2992

ArticleYear
Phase I study of pulsatile 3-day administration of afatinib (BIBW 2992) in combination with docetaxel in advanced solid tumors.
    Investigational new drugs, 2013, Volume: 31, Issue:3

    Topics: Adult; Afatinib; Aged; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; Drug Administration Schedule; Female; Gastrointestinal Diseases; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasms; Quinazolines; Skin Diseases; Taxoids

2013
Phase I dose-escalation study of afatinib, an ErbB family blocker, plus docetaxel in patients with advanced cancer.
    Future oncology (London, England), 2013, Volume: 9, Issue:2

    Topics: Adult; Afatinib; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; ErbB Receptors; Female; Humans; Male; Maximum Tolerated Dose; Middle Aged; Neoplasm Staging; Neoplasms; Quinazolines; Taxoids; Treatment Outcome

2013
A Phase 1 Study of Afatinib in Combination with Postoperative Radiation Therapy with and Without Weekly Docetaxel in Intermediate- and High-Risk Patients with Resected Squamous Cell Carcinoma of the Head and Neck.
    International journal of radiation oncology, biology, physics, 2019, 09-01, Volume: 105, Issue:1

    Topics: Adult; Afatinib; Aged; Antineoplastic Agents; Carcinoma, Squamous Cell; Combined Modality Therapy; Diarrhea; Disease-Free Survival; Docetaxel; Drug Administration Schedule; Female; Head and Neck Neoplasms; Humans; Hypokalemia; Male; Maximum Tolerated Dose; Middle Aged; Mouth Neoplasms; Mucositis; Postoperative Period; Prospective Studies; Radiotherapy Dosage

2019

Other Studies

6 other study(ies) available for docetaxel anhydrous and bibw 2992

ArticleYear
Acquisition of cancer stem cell-like properties in non-small cell lung cancer with acquired resistance to afatinib.
    Cancer science, 2015, Volume: 106, Issue:10

    Topics: Afatinib; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Animals; Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; Base Sequence; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Crizotinib; DNA Methylation; Docetaxel; Drug Resistance, Neoplasm; Epithelial-Mesenchymal Transition; ErbB Receptors; Female; Humans; Lung Neoplasms; Mice; Mice, Inbred NOD; Mice, SCID; MicroRNAs; Mutation; Neoplastic Stem Cells; Protein Kinase Inhibitors; Protein-Tyrosine Kinases; Pyrazoles; Pyridines; Quinazolines; Retinal Dehydrogenase; Sequence Analysis, DNA; Taxoids

2015
Singapore Cancer Network (SCAN) Guidelines for the Use of Systemic Therapy in Advanced Non-Small Cell Lung Cancer.
    Annals of the Academy of Medicine, Singapore, 2015, Volume: 44, Issue:10

    Topics: Adenocarcinoma; Afatinib; Anaplastic Lymphoma Kinase; Antineoplastic Combined Chemotherapy Protocols; Bevacizumab; Carcinoma, Large Cell; Carcinoma, Non-Small-Cell Lung; Crizotinib; Docetaxel; Erlotinib Hydrochloride; Gefitinib; Genes, erbB-1; Humans; Lung Neoplasms; Maintenance Chemotherapy; Pemetrexed; Pyrazoles; Pyridines; Quinazolines; Receptor Protein-Tyrosine Kinases; Singapore; Taxoids; Translocation, Genetic

2015
ERBB2-Mutated Metastatic Non-Small Cell Lung Cancer: Response and Resistance to Targeted Therapies.
    Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer, 2017, Volume: 12, Issue:5

    Topics: Adenocarcinoma; Ado-Trastuzumab Emtansine; Adult; Afatinib; Aged; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Class I Phosphatidylinositol 3-Kinases; Docetaxel; Drug Resistance, Neoplasm; Female; Gene Dosage; Genes, erbB-2; Humans; Lung Neoplasms; Male; Maytansine; Middle Aged; Molecular Targeted Therapy; Paclitaxel; Quinazolines; Retrospective Studies; Taxoids; Trastuzumab; Vinblastine; Vinorelbine

2017
Appendix 7: Metastatic non-small-cell lung cancer (1): MCBS eUpdate published online 28 June 2017 (www.esmo.org/Guidelines/Lung-and-Chest-Tumours).
    Annals of oncology : official journal of the European Society for Medical Oncology, 2017, Jul-01, Volume: 28, Issue:suppl_4

    Topics: Afatinib; Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Clinical Trials, Phase III as Topic; Docetaxel; Erlotinib Hydrochloride; Humans; Lung Neoplasms; Medical Oncology; Neoplasm Metastasis; Nivolumab; Quinazolines; Ramucirumab; Taxoids

2017
Therapeutic strategies for afatinib-resistant lung cancer harboring HER2 alterations.
    Cancer science, 2018, Volume: 109, Issue:5

    Topics: Afatinib; Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Crizotinib; Docetaxel; Drug Resistance, Neoplasm; Female; Gene Amplification; Humans; Lung Neoplasms; Mice; Neoplastic Stem Cells; Proto-Oncogene Proteins c-met; Pyrazoles; Pyridines; Quinazolines; Receptor, ErbB-2; Taxoids; Treatment Outcome; Xenograft Model Antitumor Assays

2018
[Multidisciplinary Treatment for Postoperative Recurrent Patients-Report of a Long-Term Survivor].
    Gan to kagaku ryoho. Cancer & chemotherapy, 2022, Volume: 49, Issue:10

    Topics: Adenocarcinoma of Lung; Afatinib; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcinoma, Non-Small-Cell Lung; Cisplatin; Docetaxel; ErbB Receptors; Female; Gefitinib; Humans; Lung Neoplasms; Middle Aged; Mutation; Nivolumab; Pemetrexed; Survivors

2022