Page last updated: 2024-09-04

docetaxel anhydrous and apatinib

docetaxel anhydrous has been researched along with apatinib in 11 studies

Compound Research Comparison

Studies
(docetaxel anhydrous)
Trials
(docetaxel anhydrous)
Recent Studies (post-2010)
(docetaxel anhydrous)
Studies
(apatinib)
Trials
(apatinib)
Recent Studies (post-2010) (apatinib)
12,1103,2166,920575109544

Protein Interaction Comparison

ProteinTaxonomydocetaxel anhydrous (IC50)apatinib (IC50)
Vascular endothelial growth factor receptor 2Homo sapiens (human)0.001

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's7 (63.64)24.3611
2020's4 (36.36)2.80

Authors

AuthorsStudies
Choi, M; Kim, R; Mahipal, A1
He, MF; Li, CY; Shen, LZ; Tan, AM; Wei, P; Wu, JQ; Zhai, J1
Gao, G; Ren, S; Wu, F; Zhang, S; Zhao, J; Zhou, C1
Aa, J; Feng, D; Feng, S; Gao, H; Gu, H; Peng, Y; Sun, R; Wang, G; Wang, Y; Yang, N; Zhang, J; Zhang, Y; Zhou, F1
Aa, JY; Fei, F; Feng, SQ; Huang, JQ; Sun, RB; Wang, GJ; Wang, Y; Xie, Y; Zhang, JW; Zhou, F1
Bai, H; Duan, JC; Hao, XZ; Hu, XS; Li, JL; Lin, L; Liu, YT; Wan, R; Wang, HY; Wang, J; Wang, X; Wang, Y; Wang, ZJ1
Fang, XD; Hu, X; Jiang, Q; Ma, DY; Tan, BX; Zhang, NL1
Gao, J; Liu, XL; Lu, HX; Yang, MD; Yang, WH1
Chen, Z; Ge, L; Hu, R; Hui, K; Li, T; Wang, N; Wu, X; Zhou, L1
Han, C; Li, H; Li, Z; Liu, Z; Sun, Z; Wu, Y; Zhang, J; Zhang, X1
Fan, RY; He, MF; Huang, XE; Li, CY; Shen, LZ; Wang, P; Wei, P; Wu, JQ; Zhai, J1

Reviews

3 review(s) available for docetaxel anhydrous and apatinib

ArticleYear
Second-Line Treatment of Advanced Gastric Cancer: Where Do We Stand?
    Journal of the National Comprehensive Cancer Network : JNCCN, 2015, Volume: 13, Issue:10

    Topics: Antibodies, Monoclonal; Antibodies, Monoclonal, Humanized; Asian People; Camptothecin; Docetaxel; Humans; Irinotecan; Neoplasm Staging; Pyridines; Ramucirumab; Stomach Neoplasms; Taxoids; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factor Receptor-2

2015
Successful treatment using apatinib with or without docetaxel in heavily pretreated advanced non-squamous non-small cell lung cancer: A case report and literature review.
    Cancer biology & therapy, 2018, 03-04, Volume: 19, Issue:3

    Topics: Adenocarcinoma of Lung; Aged; Antineoplastic Combined Chemotherapy Protocols; Biopsy; Carcinoma, Non-Small-Cell Lung; Docetaxel; Humans; Lung; Lung Neoplasms; Male; Neoplasm Staging; Pyridines; Tomography, X-Ray Computed; Treatment Outcome

2018
Efficacy and safety of apatinib alone or apatinib plus paclitaxel/docetaxel versus paclitaxel/docetaxel in the treatment of advanced non-small cell lung cancer: A meta-analysis.
    Thoracic cancer, 2021, Volume: 12, Issue:21

    Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Small-Cell Lung; Docetaxel; Humans; Lung Neoplasms; Paclitaxel; Protein Kinase Inhibitors; Pyridines

2021

Trials

2 trial(s) available for docetaxel anhydrous and apatinib

ArticleYear
Apatinib, a novel VEGFR inhibitor plus docetaxel in advanced lung adenocarcinoma patients with wild-type EGFR: a phase I trial.
    Investigational new drugs, 2019, Volume: 37, Issue:4

    Topics: Adenocarcinoma of Lung; Adult; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Docetaxel; ErbB Receptors; Female; Humans; Lung Neoplasms; Male; Maximum Tolerated Dose; Middle Aged; Protein Kinase Inhibitors; Pyridines; Receptors, Vascular Endothelial Growth Factor; Treatment Outcome

2019
Efficacy and safety of apatinib plus docetaxel as the second or above line treatment in advanced nonsquamous NSCLC: A multi center prospective study.
    Medicine, 2019, Volume: 98, Issue:26

    Topics: Adult; Aged; Antineoplastic Agents; Carcinoma, Non-Small-Cell Lung; Disease Progression; Docetaxel; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Lung Neoplasms; Male; Middle Aged; Preliminary Data; Prospective Studies; Protein Kinase Inhibitors; Pyridines; Retreatment; Survival Analysis; Treatment Outcome; Tubulin Modulators

2019

Other Studies

6 other study(ies) available for docetaxel anhydrous and apatinib

ArticleYear
Patient-derived xenograft in zebrafish embryos: a new platform for translational research in gastric cancer.
    Journal of experimental & clinical cancer research : CR, 2017, Nov-15, Volume: 36, Issue:1

    Topics: Aged; Animals; Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Cell Survival; China; Disease Models, Animal; Docetaxel; Female; Fluorouracil; Humans; Male; Microinjections; Middle Aged; Neoplasm Invasiveness; Neoplasm Transplantation; Pyridines; Stomach Neoplasms; Taxoids; Translational Research, Biomedical; Treatment Outcome; Zebrafish

2017
Application of liquid chromatography-tandem mass spectrometry to study the effect of docetaxel on pharmacokinetics and tissue distribution of apatinib in mice.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2018, Apr-15, Volume: 1083

    Topics: Animals; Chromatography, Liquid; Docetaxel; Linear Models; Male; Mice; Mice, Inbred BALB C; Pyridines; Reproducibility of Results; Sensitivity and Specificity; Tandem Mass Spectrometry; Taxoids; Tissue Distribution

2018
Combined treatment with apatinib and docetaxel in A549 xenograft mice and its cellular pharmacokinetic basis.
    Acta pharmacologica Sinica, 2018, Volume: 39, Issue:10

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Docetaxel; Drug Synergism; Humans; Liver; Male; Mice, Nude; Protective Agents; Pyridines; Up-Regulation; Xenograft Model Antitumor Assays

2018
[Summary of clinical research progression of apatinib combined with docetaxel in second-line treatment of advanced gastric cancer].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2020, Jul-23, Volume: 42, Issue:7

    Topics: Antineoplastic Agents; Disease Progression; Docetaxel; Humans; Pyridines; Stomach Neoplasms

2020
Apatinib sensitizes chemoresistant NSCLC cells to doxetaxel via regulating autophagy and enhances the therapeutic efficacy in advanced and refractory/recurrent NSCLC.
    Molecular medicine reports, 2020, Volume: 22, Issue:5

    Topics: A549 Cells; Aged; Autophagy; Beclin-1; Carcinoma, Non-Small-Cell Lung; Cell Line, Tumor; Cell Proliferation; Cell Survival; Docetaxel; Drug Resistance, Neoplasm; Drug Synergism; Female; Gene Expression Regulation, Neoplastic; Humans; Lung Neoplasms; Male; Microtubule-Associated Proteins; Middle Aged; Pyridines

2020
Docetaxel and 5-FU enhanced the inhibitory effects of apatinib and ramucirumab on growth and migration of gastric cancer.
    Life sciences, 2022, May-01, Volume: 296

    Topics: Angiogenesis Inhibitors; Animals; Animals, Genetically Modified; Antibodies, Monoclonal, Humanized; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Cell Movement; Cell Proliferation; Docetaxel; Embryo, Nonmammalian; Fluorouracil; Humans; Proto-Oncogene Proteins c-akt; Pyridines; Ramucirumab; Stomach Neoplasms; Vascular Endothelial Growth Factor Receptor-2; Xenograft Model Antitumor Assays; Zebrafish

2022