docetaxel anhydrous has been researched along with alpha-naphthoflavone in 4 studies
| Studies (docetaxel anhydrous) | Trials (docetaxel anhydrous) | Recent Studies (post-2010) (docetaxel anhydrous) | Studies (alpha-naphthoflavone) | Trials (alpha-naphthoflavone) | Recent Studies (post-2010) (alpha-naphthoflavone) |
|---|---|---|---|---|---|
| 12,110 | 3,216 | 6,920 | 665 | 1 | 142 |
| Protein | Taxonomy | docetaxel anhydrous (IC50) | alpha-naphthoflavone (IC50) |
|---|---|---|---|
| Carboxylic ester hydrolase | Sus scrofa (pig) | 0.0478 | |
| cGMP-specific 3',5'-cyclic phosphodiesterase | Homo sapiens (human) | 2.3034 | |
| Cytochrome P450 1A1 | Homo sapiens (human) | 0.1921 | |
| Cytochrome P450 1A2 | Homo sapiens (human) | 0.1698 | |
| Aromatase | Homo sapiens (human) | 1.035 | |
| Substance-K receptor | Homo sapiens (human) | 5.8471 | |
| Sodium-dependent dopamine transporter | Rattus norvegicus (Norway rat) | 0.01 | |
| Thromboxane-A synthase | Homo sapiens (human) | 6.7608 | |
| Adenosine receptor A1 | Homo sapiens (human) | 1.1325 | |
| Aryl hydrocarbon receptor | Mus musculus (house mouse) | 0.025 | |
| Sodium-dependent serotonin transporter | Rattus norvegicus (Norway rat) | 0.05 | |
| DNA-dependent protein kinase catalytic subunit | Homo sapiens (human) | 4.98 | |
| Cytochrome P450 1B1 | Homo sapiens (human) | 0.0449 | |
| Broad substrate specificity ATP-binding cassette transporter ABCG2 | Homo sapiens (human) | 1.355 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 2 (50.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cao, C; Chen, W; Hu, J; Shi, Y; Wang, L; Ye, W; Zhou, L; Zhou, W | 1 |
| Beloglazkina, EK; Ber, AP; Borisova, YA; Chepikova, OE; Erofeev, A; Gorelkin, P; Khazanova, ES; Khudyakov, AD; Kolmogorov, VS; Kovalev, S; Machulkin, AE; Majouga, AG; Nimenko, EA; Pankratov, AA; Petrov, SA; Plotnikova, EA; Pokrovsky, VS; Polshakov, VI; Shafikov, RR; Skvortsov, DA; Smirnova, GB; Uspenskaya, AA; Vaneev, AN; Zamyatnin, AA; Zyk, NU; Zyk, NV | 1 |
| Bournique, B; Lemarié, A | 1 |
| Cui, J; Cui, Q; Li, S; Meng, Q; Zhang, X; Zhou, W | 1 |
4 other study(ies) available for docetaxel anhydrous and alpha-naphthoflavone
| Article | Year |
|---|---|
Design and synthesis of α-naphthoflavone chimera derivatives able to eliminate cytochrome P450 (CYP)1B1-mediated drug resistance via targeted CYP1B1 degradation.
Topics: Benzoflavones; Cell Line, Tumor; Cytochrome P-450 CYP1B1; Docetaxel; Drug Design; Drug Resistance, Neoplasm; Humans; Proteolysis; Thalidomide | 2020 |
Synthesis, Characterization, and Preclinical Evaluation of a Small-Molecule Prostate-Specific Membrane Antigen-Targeted Monomethyl Auristatin E Conjugate.
Topics: Antigens, Surface; Cell Line, Tumor; Coordination Complexes; Glutamate Carboxypeptidase II; Humans; Male; Microsomes, Liver; Oligopeptides; Prostatic Neoplasms; Reactive Oxygen Species; Xenograft Model Antitumor Assays | 2021 |
Docetaxel (Taxotere) is not metabolized by recombinant human CYP1B1 in vitro, but acts as an effector of this isozyme.
Topics: Antineoplastic Agents, Phytogenic; Aryl Hydrocarbon Hydroxylases; Benzoflavones; Catalysis; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP1B1; Docetaxel; Estradiol; Humans; In Vitro Techniques; Kinetics; Microsomes, Liver; Paclitaxel; Recombinant Proteins; Spectrometry, Fluorescence; Taxoids | 2002 |
Design and Synthesis of New α-Naphthoflavones as Cytochrome P450 (CYP) 1B1 Inhibitors To Overcome Docetaxel-Resistance Associated with CYP1B1 Overexpression.
Topics: Antineoplastic Agents; Benzoflavones; Cell Line, Tumor; Cytochrome P-450 CYP1B1; Docetaxel; Drug Resistance, Neoplasm; Humans; Molecular Docking Simulation; Neoplasms; Taxoids | 2015 |