Page last updated: 2024-09-04

docetaxel anhydrous and abt-737

docetaxel anhydrous has been researched along with abt-737 in 4 studies

Compound Research Comparison

Studies
(docetaxel anhydrous)
Trials
(docetaxel anhydrous)
Recent Studies (post-2010)
(docetaxel anhydrous)
Studies
(abt-737)
Trials
(abt-737)
Recent Studies (post-2010) (abt-737)
12,1103,2166,9206320484

Protein Interaction Comparison

ProteinTaxonomydocetaxel anhydrous (IC50)abt-737 (IC50)
Bcl-2-like protein 11Homo sapiens (human)0.002
Apoptosis regulator Bcl-2Homo sapiens (human)0.0206
Alpha-1B adrenergic receptorRattus norvegicus (Norway rat)0.0003
Alpha-2B adrenergic receptorRattus norvegicus (Norway rat)0.0003
Alpha-2C adrenergic receptorRattus norvegicus (Norway rat)0.0003
Alpha-2A adrenergic receptorRattus norvegicus (Norway rat)0.0003
Adenosine receptor A2aRattus norvegicus (Norway rat)0.02
BH3-interacting domain death agonistHomo sapiens (human)0.0485
Apoptosis regulator BAX Homo sapiens (human)0.023
Bcl-2-like protein 1Homo sapiens (human)0.0207
Induced myeloid leukemia cell differentiation protein Mcl-1Homo sapiens (human)0.0248
Aspartyl/asparaginyl beta-hydroxylaseHomo sapiens (human)3.44
Bcl-2 homologous antagonist/killerHomo sapiens (human)0.0335
Bcl-2-like protein 2Homo sapiens (human)0.0335
Bcl-2-binding component 3, isoforms 1/2Homo sapiens (human)0.0003

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's4 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Bazan, F; Dixit, VM; Dornan, D; Eastham-Anderson, J; Ferrando, R; French, DM; Huang, DC; Huang, X; Lill, JR; Liu, J; Maecker, H; O'Rourke, K; Schwickart, M; Yue, P1
Breslin, K; Deb, S; Feleppa, F; Fox, SB; Generali, D; Huang, DC; Lee, L; Lim, E; Lindeman, GJ; Oakes, SR; Ritchie, ME; Smyth, GK; Strasser, A; Takano, E; Vaillant, F; Visvader, JE; Ward, T1
Ding, DG; Du, GH; Hao, JW; Liu, ZH; Mao, XP1
Arichi, N; Harada, M; Harashima, N; Hiraki, M; Naora, K; Nishimura, N; Shiina, H; Tamaki, H1

Other Studies

4 other study(ies) available for docetaxel anhydrous and abt-737

ArticleYear
Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival.
    Nature, 2010, Jan-07, Volume: 463, Issue:7277

    Topics: Animals; Apoptosis; Biphenyl Compounds; Cell Line; Cell Line, Tumor; Cell Survival; DNA Damage; Docetaxel; Etoposide; Female; Gene Expression Regulation, Neoplastic; Gene Knockdown Techniques; Half-Life; Humans; Lysine; Mice; Mice, SCID; Myeloid Cell Leukemia Sequence 1 Protein; Neoplasms; Nitrophenols; Phosphorylation; Piperazines; Polyubiquitin; Prognosis; Protein Binding; Protein Stability; Proto-Oncogene Proteins c-bcl-2; RNA Interference; Sulfonamides; Taxoids; Ubiquitin Thiolesterase; Ubiquitination; Ultraviolet Rays; Xenograft Model Antitumor Assays

2010
Sensitization of BCL-2-expressing breast tumors to chemotherapy by the BH3 mimetic ABT-737.
    Proceedings of the National Academy of Sciences of the United States of America, 2012, Feb-21, Volume: 109, Issue:8

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Apoptosis Regulatory Proteins; Bcl-2-Like Protein 11; bcl-X Protein; Biphenyl Compounds; Breast Neoplasms; Cell Line, Tumor; Docetaxel; Female; Humans; Membrane Proteins; Mice; Myeloid Cell Leukemia Sequence 1 Protein; Nitrophenols; Piperazines; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Remission Induction; Sulfonamides; Taxoids; Xenograft Model Antitumor Assays

2012
[The effect of cell killing by ABT-737 synergized with docetaxel in human prostate cancer PC-3 cells].
    Zhonghua wai ke za zhi [Chinese journal of surgery], 2012, Feb-01, Volume: 50, Issue:2

    Topics: Apoptosis; bcl-X Protein; Biphenyl Compounds; Caspase 3; Cell Cycle; Cell Line, Tumor; Docetaxel; Drug Synergism; Humans; Male; Myeloid Cell Leukemia Sequence 1 Protein; Nitrophenols; Piperazines; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Sulfonamides; Taxoids

2012
Bcl-2 family inhibition sensitizes human prostate cancer cells to docetaxel and promotes unexpected apoptosis under caspase-9 inhibition.
    Oncotarget, 2014, Nov-30, Volume: 5, Issue:22

    Topics: Aniline Compounds; Animals; Antineoplastic Combined Chemotherapy Protocols; Apoptosis; Biphenyl Compounds; Bridged Bicyclo Compounds, Heterocyclic; Caspase 9; Caspase Inhibitors; Cell Line, Tumor; Docetaxel; Drug Synergism; Humans; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Nitrophenols; Piperazines; Prostatic Neoplasms; Proto-Oncogene Proteins c-bcl-2; Sulfonamides; Taxoids; Transfection; Xenograft Model Antitumor Assays

2014