docetaxel has been researched along with paclitaxel in 40 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 10 (25.00) | 18.2507 |
2000's | 21 (52.50) | 29.6817 |
2010's | 9 (22.50) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
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Guénard, D; Guéritte-Voegelein, F; Lavelle, F; Le Goff, MT; Mangatal, L; Potier, P | 1 |
Ali, SM; Aubé, J; Georg, GI; Hoemann, MZ; Jayasinghe, LR; McCall, R; Mitscher, LA | 1 |
Ali, SM; Datta, A; Georg, GI; Jayasinghe, LR; Vander Velde, DG; Zygmunt, J | 1 |
Boge, TC; Georg, GI; Himes, RH; Vander Velde, DG | 1 |
Bernacki, RJ; Bissery, MC; Bounaud, PY; Kuduk, SD; Michaud, E; Ojima, I; Pera, P; Slater, JC; Veith, JM; Vrignaud, P | 1 |
Ali, SM; Aubé, J; Georg, GI; Hoemann, MZ; Jayasinghe, LR; Mitscher, LA | 1 |
Bernacki, RJ; Gimi, RH; Kuduk, SD; Ojima, I; Park, YH; Pera, P; Slater, JC; Sun, CM; Takeuchi, CS; Veith, JM | 1 |
Bernacki, RJ; Kuduk, SD; Ojima, I; Pera, P; Veith, JM | 1 |
Chidester, CG; DeKoning, TF; Dobrowolski, PJ; Gebhard, I; Johnson, RA; Kelly, RC; Lopes, NM; Mattern, SJ; McGovren, JP; Nidy, EG; Pitts, TW; Qualls, SJ; Weed, SD; Wicnienski, NA | 1 |
Bernacki, RJ; Borella, CP; Geng, X; Lin, S; Miller, ML; Ojima, I; Pera, P; Wang, T | 1 |
Fang, QC; Fang, WS; Liu, HY; Liu, Y; Wang, L; Xu, SF | 1 |
Chiba, J; Iimura, S; Ishiyama, T; Soga, T; Terasawa, H; Uoto, K; Yoshino, T | 1 |
Bartle, LM; Borella, CP; Chari, RV; Geng, X; Goldmacher, VS; Leece, BA; Ojima, I; Qu, C; Wilhelm, SD; Wu, X; Xie, H | 1 |
Chiba, J; Ishiyama, T; Iwahana, M; Jimbo, T; Soga, T; Takeda, Y; Tanaka, N; Terasawa, H; Uoto, K; Yoshino, T | 1 |
Chari, RV; Goldmacher, VS; Leece, BA; Miller, ML; Ojima, I; Roller, EE; Wu, X | 1 |
Baloglu, E; Cavanagh, EE; Chari, RV; Goldmacher, VS; Leece, BA; Miller, ML; Roller, EE | 1 |
Dubois, J; Guénard, D; Guéritte, F; Querolle, O; Roussi, F; Thoret, S | 1 |
Li, Y; Li, YH; Wang, YH; Yang, L; Yang, SL | 1 |
Bernacki, RJ; Chen, J; Kuznetsova, L; Ojima, I; Pepe, A; Pera, P; Sun, L; Veith, JM; Wu, X | 1 |
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
Andreu, JM; Barasoain, I; Buey, RM; Calvo, E; Cerezo, G; Day, BW; Díaz, JF; Edler, MC; Hamel, E; López, JA; Matesanz, R; Pineda, O; Sorensen, EJ; Vanderwal, CD | 1 |
Afragola, J; Ayral-Kaloustian, S; Beyer, C; Gibbons, J; Hernandez, R; Lucas, J; Nguyen, T; Zhang, N | 1 |
Ballatore, C; Deiches, RF; Huryn, D; Hyde, E; Lee, VM; Smith, AB; Trojanowski, JQ | 1 |
Hansch, C; Verma, RP | 1 |
Lombardo, F; Obach, RS; Waters, NJ | 1 |
Bar-Sagi, D; Bernacki, RJ; Borella, CP; Chen, J; Gallager, D; Geng, X; Guerriero, JL; Horwitz, SB; Kuznetsova, L; Lin, S; Mallen-St Clair, J; Miller, ML; Ojima, I; Pera, P; Qu, C; Sun, L; Veith, JM; Wang, T; Xia, S; Zanardi, I; Zhao, X | 1 |
Allegro, D; Aubert, G; Barthélémy-Requin, M; Béclin, C; Cresteil, T; De Angelis, F; Di, C; Gatti, E; Kraus, JL; Laras, Y; Moret, V; Pasquini, L; Petrucci, E; Peyrot, V; Pierre, P; Ping, DQ; Rolland, A; Testa, U | 1 |
Ke, B; Qin, Y; Qu, Y; Zhao, F | 1 |
Barasoain, I; Díaz, JF; Fang, WS; Li, X; Matesanz, R | 1 |
Das, M; Ojima, I | 1 |
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
Benfenati, E; Raska, I; Toropov, AA; Toropova, AP | 1 |
Barasoain, I; Carda, M; Díaz, JF; Falomir, E; García-Pla, J; Marco, JA; Murga, J; Notararigo, S; Trigili, C | 1 |
Akula, B; Bharathi, EV; Billa, VK; Cosenza, SC; Gallo, JM; Lv, H; Mallireddigari, MR; Padgaonkar, A; Pallela, VR; Reddy, EP; Reddy, MV; Subbaiah, DR | 1 |
Chang, J; Hao, XD; Hao, YP; Lu, HF; Sun, X; Yu, JM | 1 |
Hoye, TR; Kalscheuer, S; Macosko, CW; Michel, AR; Panyam, J; Wohl, AR | 1 |
Bailey-Downs, LC; Bastian, A; Disch, BC; Dybdal-Hargreaves, NF; Gangjee, A; Hamel, E; Ihnat, M; Mooberry, SL; Raghavan, S; Rohena, CC; Thorpe, JE; Zhang, X | 1 |
Bai, R; Bailey-Downs, LC; Bastian, A; Disch, BC; Gangjee, A; Hamel, E; Ihnat, MA; Pavana, RK; Thorpe, JE | 1 |
Barasoain, I; Canales, A; Díaz, JF; Fang, WS; Jímenez-Barbero, J; Matesanz, R; Nogales, A; Ojima, I; Pera, B; Rodríguez-Salarichs, J; Trigili, C; Zanardi, I | 1 |
1 review(s) available for docetaxel and paclitaxel
Article | Year |
---|---|
Recent advances in the chemistry and biology of new generation taxoids.
Topics: Molecular Structure; Taxoids | 2009 |
39 other study(ies) available for docetaxel and paclitaxel
Article | Year |
---|---|
Relationships between the structure of taxol analogues and their antimitotic activity.
Topics: Alkaloids; Animals; Antineoplastic Agents; Brain; Cell Division; Chemical Phenomena; Chemistry; Leukemia P388; Mice; Microtubules; Molecular Conformation; Molecular Structure; Paclitaxel; Stereoisomerism; Structure-Activity Relationship; Swine; Tubulin | 1991 |
Novel cytotoxic 3'-(tert-butyl) 3'-dephenyl analogs of paclitaxel and docetaxel.
Topics: Antineoplastic Agents, Phytogenic; Docetaxel; Humans; Melanoma, Experimental; Microtubules; Molecular Structure; Paclitaxel; Solubility; Taxoids; Tumor Cells, Cultured | 1995 |
Structure-activity studies of antitumor taxanes: synthesis of novel C-13 side chain homologated taxol and taxotere analogs.
Topics: Docetaxel; In Vitro Techniques; Molecular Conformation; Paclitaxel; Structure-Activity Relationship; Taxoids; Tubulin | 1994 |
The effect of the aromatic rings of taxol on biological activity and solution conformation: synthesis and evaluation of saturated taxol and taxotere analogues.
Topics: Antineoplastic Agents; Cell Survival; Chloroform; Dimethyl Sulfoxide; Docetaxel; Melanoma, Experimental; Microtubules; Molecular Conformation; Molecular Structure; Paclitaxel; Solutions; Structure-Activity Relationship; Taxoids | 1994 |
Syntheses and structure-activity relationships of the second-generation antitumor taxoids: exceptional activity against drug-resistant cancer cells.
Topics: Animals; Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Breast Neoplasms; Docetaxel; Drug Resistance, Neoplasm; Female; Humans; Melanoma, Experimental; Mice; Mice, Nude; Molecular Structure; Ovarian Neoplasms; Paclitaxel; Structure-Activity Relationship; Taxoids; Tumor Cells, Cultured | 1996 |
Butitaxel analogues: synthesis and structure-activity relationships.
Topics: Animals; Antineoplastic Agents; Drug Screening Assays, Antitumor; Melanoma, Experimental; Mice; Microtubules; Paclitaxel; Solubility; Structure-Activity Relationship; Taxoids | 1997 |
Syntheses and structure-activity relationships of taxoids derived from 14 beta-hydroxy-10-deacetylbaccatin III.
Topics: Antineoplastic Agents, Phytogenic; ATP Binding Cassette Transporter, Subfamily B, Member 1; Docetaxel; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Humans; Magnetic Resonance Spectroscopy; Molecular Conformation; Molecular Structure; Paclitaxel; Structure-Activity Relationship; Taxoids; Tumor Cells, Cultured | 1997 |
Synthesis and structure-activity relationships of nonaromatic taxoids: effects of alkyl and alkenyl ester groups on cytotoxicity.
Topics: Antineoplastic Agents, Phytogenic; Breast Neoplasms; Docetaxel; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Esters; Female; Humans; Magnetic Resonance Spectroscopy; Models, Molecular; Molecular Structure; Ovarian Neoplasms; Paclitaxel; Structure-Activity Relationship; Taxoids; Tumor Cells, Cultured | 1997 |
12,13-isotaxanes: synthesis of new potent analogs and X-ray crystallographic confirmation of structure.
Topics: Alkaloids; Animals; Antineoplastic Agents; Bridged-Ring Compounds; Crystallography, X-Ray; Female; Humans; Melanoma, Experimental; Mice; Mice, Inbred Strains; Molecular Conformation; Molecular Structure; Ovarian Neoplasms; Paclitaxel; Taxoids; Tumor Cells, Cultured | 1997 |
Synthesis and structure-activity relationships of new second-generation taxoids.
Topics: Alkaloids; Antineoplastic Agents; Drug Screening Assays, Antitumor; Humans; Paclitaxel; Structure-Activity Relationship; Tumor Cells, Cultured | 1999 |
Synthesis and cytotoxicity of 2alpha-amido docetaxel analogues.
Topics: Antineoplastic Agents, Phytogenic; Docetaxel; Drug Resistance, Neoplasm; Inhibitory Concentration 50; Paclitaxel; Structure-Activity Relationship; Taxoids; Tumor Cells, Cultured | 2002 |
New highly active taxoids from 9beta-dihydrobaccatin-9,10-acetals. Part 2.
Topics: Antineoplastic Agents, Phytogenic; Bridged-Ring Compounds; Chemical Phenomena; Chemistry, Physical; Chromatography, High Pressure Liquid; Drug Screening Assays, Antitumor; Indicators and Reagents; Magnetic Resonance Spectroscopy; Paclitaxel; Solubility; Stereoisomerism; Structure-Activity Relationship; Taxoids; Tumor Cells, Cultured | 2002 |
Tumor-specific novel taxoid-monoclonal antibody conjugates.
Topics: Animals; Antibodies, Monoclonal; Antineoplastic Agents; ErbB Receptors; Humans; Immunoconjugates; Mice; Mice, SCID; Paclitaxel; Prodrugs; Structure-Activity Relationship; Xenograft Model Antitumor Assays | 2002 |
New highly active taxoids from 9beta-dihydrobaccatin-9,10-acetals. Part 3.
Topics: Animals; Antineoplastic Agents, Phytogenic; Cell Survival; Crystallography, X-Ray; Drug Screening Assays, Antitumor; Humans; Indicators and Reagents; Melanoma, Experimental; Mice; Molecular Conformation; Neoplasm Transplantation; Paclitaxel; Solubility; Tumor Cells, Cultured | 2003 |
Synthesis of potent taxoids for tumor-specific delivery using monoclonal antibodies.
Topics: Antibodies, Monoclonal; Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Drug Delivery Systems; Drug Design; Drug Screening Assays, Antitumor; Humans; Models, Molecular; Molecular Structure; Paclitaxel; Structure-Activity Relationship; Taxoids | 2004 |
Synthesis and biological evaluation of novel taxoids designed for targeted delivery to tumors.
Topics: Antineoplastic Agents; Drug Delivery Systems; Drug Evaluation, Preclinical; Humans; Taxoids; Tumor Cells, Cultured | 2004 |
Synthesis of C2-C3'N-linked macrocyclic taxoids. Novel docetaxel analogues with high tubulin activity.
Topics: Antineoplastic Agents; Binding Sites; Docetaxel; Drug Screening Assays, Antitumor; Humans; KB Cells; Models, Molecular; Molecular Conformation; Structure-Activity Relationship; Taxoids; Tubulin | 2004 |
Modeling K(m) values using electrotopological state: substrates for cytochrome P450 3A4-mediated metabolism.
Topics: Computational Biology; Cyclohexanols; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Molecular Structure; Principal Component Analysis; Pyrrolizidine Alkaloids; Quantitative Structure-Activity Relationship; Reproducibility of Results; Substrate Specificity; Venlafaxine Hydrochloride | 2005 |
Syntheses and evaluation of novel fatty acid-second-generation taxoid conjugates as promising anticancer agents.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Drug Screening Assays, Antitumor; Fatty Acids, Unsaturated; Humans; Molecular Conformation; Structure-Activity Relationship; Taxoids | 2006 |
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cyclostreptin binds covalently to microtubule pores and lumenal taxoid binding sites.
Topics: Alkanes; Amino Acid Sequence; Asparagine; Binding Sites; Binding, Competitive; Carbamates; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Docetaxel; Epothilones; Humans; Inhibitory Concentration 50; Lactones; Mass Spectrometry; Microtubules; Models, Chemical; Models, Molecular; Molecular Sequence Data; Paclitaxel; Polycyclic Compounds; Protein Binding; Pyrones; Taxoids; Threonine; Tubulin; Tubulin Modulators | 2007 |
Synthesis and SAR of [1,2,4]triazolo[1,5-a]pyrimidines, a class of anticancer agents with a unique mechanism of tubulin inhibition.
Topics: Administration, Oral; Animals; Cell Proliferation; Female; Humans; Injections, Intravenous; Mice; Mice, Nude; Pyrimidines; Stereoisomerism; Structure-Activity Relationship; Triazoles; Tubulin Modulators; Xenograft Model Antitumor Assays | 2007 |
Paclitaxel C-10 carbamates: potential candidates for the treatment of neurodegenerative tauopathies.
Topics: Animals; Blood-Brain Barrier; Brain; Carbamates; Chemistry, Pharmaceutical; Drug Design; Humans; Mice; Models, Chemical; Neurodegenerative Diseases; Paclitaxel; Permeability; Tauopathies; Time Factors | 2007 |
A QSAR study for the cytotoxic activities of taxoids against macrophage (MPhi)-like cells.
Topics: Animals; Cells, Cultured; Humans; Macrophages; Quantitative Structure-Activity Relationship; Structure-Activity Relationship; Taxoids | 2009 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Design, synthesis, and biological evaluation of new-generation taxoids.
Topics: Animals; Antineoplastic Agents; Biopolymers; Cell Line, Tumor; Drug Design; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Female; Humans; Male; Mice; Mice, Nude; Neoplasm Transplantation; Paclitaxel; Point Mutation; Structure-Activity Relationship; Taxoids; Transplantation, Heterologous; Tubulin | 2008 |
Discovery of a new family of bis-8-hydroxyquinoline substituted benzylamines with pro-apoptotic activity in cancer cells: synthesis, structure-activity relationship, and action mechanism studies.
Topics: Antineoplastic Agents; Apoptosis; Benzylamines; Caspases; Cell Line, Tumor; Drug Screening Assays, Antitumor; Female; Humans; Hydroxyquinolines; Male; Structure-Activity Relationship; TNF-Related Apoptosis-Inducing Ligand | 2009 |
Synthesis and biological evaluation of novel 3'-N-tert-butylsulfonyl analogues of docetaxel.
Topics: Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Docetaxel; Drug Screening Assays, Antitumor; HeLa Cells; Humans; KB Cells; Paclitaxel; Sulfonic Acids; Taxoids | 2008 |
Synthesis and biological activities of high affinity taxane-based fluorescent probes.
Topics: Anisotropy; Bridged-Ring Compounds; Chemistry, Pharmaceutical; Dose-Response Relationship, Drug; Drug Design; Fluorescein; Fluorescent Dyes; Ligands; Microtubules; Models, Chemical; Plant Extracts; Taxoids; Temperature; Thermodynamics; Tubulin | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
QSPR modeling of octanol/water partition coefficient of antineoplastic agents by balance of correlations.
Topics: Antineoplastic Agents; Models, Chemical; Octanols; Quantitative Structure-Activity Relationship; Water | 2010 |
Design and synthesis of pironetin analogues with simplified structure and study of their interactions with microtubules.
Topics: Antineoplastic Agents; Cell Proliferation; Dose-Response Relationship, Drug; Drug Design; Drug Screening Assays, Antitumor; Humans; Microtubules; Molecular Structure; Pyrones; Stereoisomerism; Structure-Activity Relationship; Tubulin; Tumor Cells, Cultured | 2011 |
Design, synthesis, and biological evaluation of (E)-N-aryl-2-arylethenesulfonamide analogues as potent and orally bioavailable microtubule-targeted anticancer agents.
Topics: Administration, Oral; Animals; Antineoplastic Agents; Biological Availability; Blood-Brain Barrier; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Survival; Drug Design; Drug Resistance, Neoplasm; HCT116 Cells; Humans; K562 Cells; MCF-7 Cells; Mice; Mice, Nude; Microtubules; Neoplasms; Polymerization; Sulfonamides; Tubulin; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
Design, synthesis and cytotoxicity of novel 3'-N-alkoxycarbonyl docetaxel analogs.
Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Survival; Docetaxel; Drug Design; Humans; Paclitaxel; Stereoisomerism; Structure-Activity Relationship; Taxoids | 2013 |
Silicate esters of paclitaxel and docetaxel: synthesis, hydrophobicity, hydrolytic stability, cytotoxicity, and prodrug potential.
Topics: Antineoplastic Agents, Phytogenic; Cell Line; Cell Survival; Coloring Agents; Docetaxel; Drug Delivery Systems; Drug Design; Humans; Hydrolysis; Hydrophobic and Hydrophilic Interactions; Indicators and Reagents; Kinetics; Models, Molecular; Molecular Conformation; Nanoparticles; Paclitaxel; Prodrugs; Silicates; Taxoids; Tetrazolium Salts; Thiazoles | 2014 |
The design and discovery of water soluble 4-substituted-2,6-dimethylfuro[2,3-d]pyrimidines as multitargeted receptor tyrosine kinase inhibitors and microtubule targeting antitumor agents.
Topics: Aniline Compounds; Animals; Antineoplastic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Dose-Response Relationship, Drug; Drug Discovery; Drug Screening Assays, Antitumor; Female; HeLa Cells; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; Microtubules; Neoplasms, Experimental; Protein Kinase Inhibitors; Pyrimidines; Receptor Protein-Tyrosine Kinases; Solubility; Structure-Activity Relationship; Water | 2014 |
Discovery of antitubulin agents with antiangiogenic activity as single entities with multitarget chemotherapy potential.
Topics: | 2014 |
Taxanes with high potency inducing tubulin assembly overcome tumoural cell resistances.
Topics: Animals; Antineoplastic Agents; Binding Sites; Bridged-Ring Compounds; Cattle; Cell Cycle; Cell Line, Tumor; Cytoskeleton; Dose-Response Relationship, Drug; Drug Resistance, Neoplasm; HeLa Cells; Humans; Microtubules; Models, Molecular; Nuclear Magnetic Resonance, Biomolecular; Structure-Activity Relationship; Taxoids; Thermodynamics; Tubulin | 2014 |