Page last updated: 2024-08-23

dobutamine and nifedipine

dobutamine has been researched along with nifedipine in 21 studies

Research

Studies (21)

TimeframeStudies, this research(%)All Research%
pre-19904 (19.05)18.7374
1990's7 (33.33)18.2507
2000's4 (19.05)29.6817
2010's6 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Topliss, JG; Yoshida, F1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Motley, ED; Nichols, AJ; Ruffolo, RR1
Burkhoff, D; Sagawa, K; Sugiura, S; Yue, DT1
Thoolen, MJ; Timmermans, PB1
Burkhoff, D; Franz, MR; Oikawa, RY; Sagawa, K; Schaefer, J; Yue, DT1
Eigenmann, R; Gerold, M; Wolfgang, H1
Coetzee, A; Genade, S; Harper, I; Hattingh, P; Lochner, A1
Kojima, S; Parmley, WW; Wikman-Coffelt, J; Wu, ST1
Abbott, J; Caputo, G; Schwartz, JB1
Bruno, G; Cordovil, A; Dodi, C; Picano, E; Pingitore, A; Sicari, R1
Taherzadeh, M; Warren, JB1
Artemiou, O; Bîrsan, T; Klepetko, W; Kranz, A; Mares, P; Taghavi, S; Zuckermann, A1
Ito, T; Miyake, T; Taki, K1
Li, H; Lu, D; Lv, X; Wang, H; Wang, Y; Yang, D; Yu, X1

Reviews

1 review(s) available for dobutamine and nifedipine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

2 trial(s) available for dobutamine and nifedipine

ArticleYear
Early experience with dobutamine stress testing and cardiac cine-tomographic imaging in the elderly: antianginal effects of nifedipine-GITS.
    Journal of the American Geriatrics Society, 1993, Volume: 41, Issue:9

    Topics: Age Factors; Angina Pectoris; Cineradiography; Coronary Angiography; Coronary Disease; Dobutamine; Double-Blind Method; Drug Delivery Systems; Edema; Exercise Test; Female; Gastrointestinal Transit; Hemodynamics; Humans; Infusions, Intravenous; Male; Middle Aged; Nifedipine; Peripheral Vascular Diseases; Rest; Tomography, X-Ray Computed

1993
Effects of antianginal therapy with a calcium antagonist and nitrates on dobutamine-atropine stress echocardiography. Comparison with exercise electrocardiography.
    European heart journal, 1997, Volume: 18, Issue:2

    Topics: Atropine; Calcium Channel Blockers; Cardiotonic Agents; Coronary Disease; Diltiazem; Dobutamine; Dose-Response Relationship, Drug; Echocardiography; Electrocardiography; Exercise Test; Female; Humans; Infusions, Intravenous; Isosorbide Dinitrate; Male; Middle Aged; Nifedipine; Nitrates; Parasympatholytics; Prospective Studies; Vasodilator Agents

1997

Other Studies

18 other study(ies) available for dobutamine and nifedipine

ArticleYear
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index

2014
The effect of pertussis toxin on alpha 1-adrenoceptor-mediated vasoconstriction by the full agonist, cirazoline, and the partial agonist, (-)-dobutamine, in pithed rats.
    Fundamental & clinical pharmacology, 1991, Volume: 5, Issue:1

    Topics: Adrenergic alpha-Agonists; Animals; Blood Pressure; Blood Vessels; Body Weight; Calcium Channels; Dobutamine; Dose-Response Relationship, Drug; GTP-Binding Proteins; Imidazoles; Male; Nifedipine; Pertussis Toxin; Rats; Rats, Inbred Strains; Receptors, Adrenergic, alpha; Vasoconstrictor Agents; Virulence Factors, Bordetella

1991
Contractility-dependent curvilinearity of end-systolic pressure-volume relations.
    The American journal of physiology, 1987, Volume: 252, Issue:6 Pt 2

    Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester; Animals; Coronary Circulation; Dobutamine; Dogs; Mathematics; Models, Cardiovascular; Myocardial Contraction; Nifedipine; Ventricular Function

1987
Equal potency of nifedipine to inhibit alpha 1-(dobutamine and BDF 6143) and alpha 2-adrenoceptor (B-HT 920) induced pressor responses in pithed rats; lack of effect of phenoxybenzamine.
    European journal of pharmacology, 1987, Aug-11, Volume: 140, Issue:2

    Topics: Adrenergic alpha-Agonists; Animals; Azepines; Blood Pressure; Decerebrate State; Dobutamine; Dose-Response Relationship, Drug; Imidazoles; Isoindoles; Male; Nifedipine; Phenoxybenzamine; Rats; Rats, Inbred Strains

1987
Influence of ventricular contractility on non-work-related myocardial oxygen consumption.
    Heart and vessels, 1987, Volume: 3, Issue:2

    Topics: Animals; Dobutamine; Dogs; Heart; Myocardial Contraction; Nifedipine; Oxygen Consumption

1987
Telemetry of cardiac left ventricular pressure in conscious dogs.
    Biotelemetry and patient monitoring, 1981, Volume: 8, Issue:1-2

    Topics: Animals; Dobutamine; Dogs; Heart Ventricles; Myocardial Contraction; Nifedipine; Pressure; Telemetry; Ventricular Function; Verapamil

1981
Effects of beta-blockers and Ca(2+)-antagonists on the response of the isolated working rat heart to adrenergic stimulants after cardioplegic arrest.
    Cardiovascular drugs and therapy, 1993, Volume: 7, Issue:6

    Topics: Adenine Nucleotides; Animals; Cardiac Output; Cardiotonic Agents; Disease Models, Animal; Dobutamine; Epinephrine; Heart; Heart Arrest, Induced; Heart Rate; In Vitro Techniques; Isoproterenol; Male; Myocardial Reperfusion; Myocardium; Nifedipine; Propranolol; Rats; Rats, Wistar; Stimulation, Chemical

1993
Relationship between intracellular calcium and oxygen consumption: effects of perfusion pressure, extracellular calcium, dobutamine, and nifedipine.
    American heart journal, 1994, Volume: 127, Issue:2

    Topics: Animals; Calcium; Coronary Circulation; Diastole; Dobutamine; Fluorescent Dyes; Heart; Indoles; Myocardial Contraction; Myocardium; Nifedipine; Oxygen Consumption; Rats; Rats, Sprague-Dawley; Systole; Ventricular Pressure

1994
Cardiac inotropes inhibit the oedema caused by nifedipine in rabbit skin.
    British journal of pharmacology, 1997, Volume: 122, Issue:6

    Topics: Animals; Bradykinin; Calcium Channel Blockers; Cardiotonic Agents; Dinoprostone; Dobutamine; Dopamine; Edema; Histamine; Isoproterenol; Male; Microcirculation; Nifedipine; Rabbits; Skin

1997
Transient left ventricular failure following bilateral lung transplantation for pulmonary hypertension.
    The Journal of heart and lung transplantation : the official publication of the International Society for Heart Transplantation, 1999, Volume: 18, Issue:4

    Topics: Adult; Alprostadil; Antihypertensive Agents; Cardiac Output, Low; Cardiotonic Agents; Catheterization, Swan-Ganz; Clonidine; Dobutamine; Echocardiography; Female; Hemodynamics; Humans; Hypertension, Pulmonary; Lung Transplantation; Male; Nifedipine; Respiratory Insufficiency; Treatment Outcome; Vasodilator Agents; Ventricular Dysfunction, Left

1999
[A case of successfully treated nifedipine-poisoning].
    Chudoku kenkyu : Chudoku Kenkyukai jun kikanshi = The Japanese journal of toxicology, 2003, Volume: 16, Issue:2

    Topics: Calcium Channel Blockers; Cathartics; Charcoal; Dobutamine; Gastric Lavage; Humans; Isotonic Solutions; Male; Middle Aged; Nifedipine; Ringer's Lactate; Treatment Outcome

2003
β₁-adrenoceptor stimulation promotes LPS-induced cardiomyocyte apoptosis through activating PKA and enhancing CaMKII and IκBα phosphorylation.
    Critical care (London, England), 2015, Mar-09, Volume: 19

    Topics: Adrenergic beta-1 Receptor Agonists; Animals; Apoptosis; Calcium Channel Blockers; Calcium-Calmodulin-Dependent Protein Kinase Type 2; Caspases; Cyclic AMP-Dependent Protein Kinases; Dobutamine; Endotoxemia; Lipopolysaccharides; Male; Mice; Mice, Inbred BALB C; Myocardial Contraction; Myocardium; Myocytes, Cardiac; Nifedipine; Norepinephrine; p38 Mitogen-Activated Protein Kinases; Phosphorylation; Receptors, Adrenergic, beta-1

2015