Page last updated: 2024-09-03

dn 1417 and gamma-aminobutyric acid

dn 1417 has been researched along with gamma-aminobutyric acid in 6 studies

*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]

*gamma-Aminobutyric Acid: The most common inhibitory neurotransmitter in the central nervous system. [MeSH]

Compound Research Comparison

Studies
(dn 1417)
Trials
(dn 1417)
Recent Studies (post-2010)
(dn 1417)
Studies
(gamma-aminobutyric acid)
Trials
(gamma-aminobutyric acid)
Recent Studies (post-2010) (gamma-aminobutyric acid)
942040,2151,4239,631

Protein Interaction Comparison

ProteinTaxonomydn 1417 (IC50)gamma-aminobutyric acid (IC50)
Gamma-aminobutyric acid receptor subunit piRattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid type B receptor subunit 2Rattus norvegicus (Norway rat)0.0292
Gamma-aminobutyric acid receptor subunit beta-1Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit deltaRattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit gamma-2Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit alpha-5Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit alpha-3Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit gamma-1Rattus norvegicus (Norway rat)0.0332
Gamma-aminobutyric acid receptor subunit alpha-2Rattus norvegicus (Norway rat)0.0323
Sodium- and chloride-dependent GABA transporter 1Rattus norvegicus (Norway rat)2.152
Gamma-aminobutyric acid receptor subunit alpha-4Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit gamma-3Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit alpha-6Rattus norvegicus (Norway rat)0.0333
Sodium- and chloride-dependent GABA transporter 1Homo sapiens (human)5.2623
Sodium- and chloride-dependent taurine transporterHomo sapiens (human)354
Sodium- and chloride-dependent GABA transporter 2Rattus norvegicus (Norway rat)2.51
Sodium- and chloride-dependent GABA transporter 3Rattus norvegicus (Norway rat)0.02
Sodium- and chloride-dependent GABA transporter 1Mus musculus (house mouse)6.349
Sodium- and chloride-dependent GABA transporter 2Mus musculus (house mouse)7.0795
Sodium- and chloride-dependent GABA transporter 3Mus musculus (house mouse)8.1283
Sodium- and chloride-dependent betaine transporterRattus norvegicus (Norway rat)0.02
Sodium- and chloride-dependent betaine transporterHomo sapiens (human)6.4082
Sodium- and chloride-dependent GABA transporter 3Homo sapiens (human)3.9953
Gamma-aminobutyric acid receptor subunit alpha-1Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit beta-3Rattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit beta-2Rattus norvegicus (Norway rat)0.0333
GABA theta subunitRattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid receptor subunit epsilonRattus norvegicus (Norway rat)0.0333
Gamma-aminobutyric acid type B receptor subunit 1Rattus norvegicus (Norway rat)0.0292

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's1 (16.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Imura, H; Kato, Y; Tatsuoka, Y2
Fukatsu, T; Kumashiro, H; Mori, N; Sato, T1
Fukuda, N; Hashimoto, T; Nagawa, Y; Saji, Y1
Inanaga, K; Ishibashi, K; Kojima, H; Nakamura, J; Tsutsumi, T; Uchimura, N; Yamada, S1
Imamura, M; Mori, M; Prasad, C; Yamada, M1

Other Studies

6 other study(ies) available for dn 1417 and gamma-aminobutyric acid

ArticleYear
Effect of DN-1417, a synthetic thyrotropin-releasing hormone analogue, on [3H]GABA binding in the cerebellum of ataxic rats.
    Neuroscience letters, 1985, Jan-07, Volume: 53, Issue:1

    Topics: Animals; Cerebellar Ataxia; Cerebellum; Cerebral Cortex; Cytarabine; gamma-Aminobutyric Acid; Male; Rats; Rats, Inbred Strains; Receptors, GABA-A; Thyrotropin-Releasing Hormone

1985
Application of liposome-entrapped drugs.
    The Japanese journal of psychiatry and neurology, 1986, Volume: 40, Issue:3

    Topics: Animals; Antineoplastic Agents; Drug Administration Routes; Epilepsy; gamma-Aminobutyric Acid; Humans; Liposomes; Microspheres; Rats; Thyrotropin-Releasing Hormone

1986
Inhibition by DN-1417 (a TRH derivative) of [3H]GABA binding in the rat brain.
    Neuroscience letters, 1983, Dec-02, Volume: 42, Issue:2

    Topics: Animals; Binding Sites; Brain; Cerebellum; Cerebral Cortex; GABA Antagonists; gamma-Aminobutyric Acid; Male; Rats; Rats, Inbred Strains; Synaptic Membranes; Thyrotropin-Releasing Hormone; Tritium

1983
Effects of TRH and an analog, DN-1417 on the activities of single neurons in the nucleus accumbens, cerebral cortex and caudate-putamen of rats.
    The Kurume medical journal, 1983, Volume: 30 Suppl

    Topics: Acetylcholine; Animals; Brain; Caudate Nucleus; Cerebral Cortex; Dopamine; Dose-Response Relationship, Drug; gamma-Aminobutyric Acid; Male; Methamphetamine; Neurons; Nucleus Accumbens; Putamen; Rats; Rats, Inbred Strains; Thyrotropin-Releasing Hormone

1983
Effects of a TRH analog (DN-1417) and TRH-T on the electroconvulsive threshold.
    The Kurume medical journal, 1983, Volume: 30 Suppl

    Topics: Animals; Anticonvulsants; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Catheters, Indwelling; Corpus Striatum; Dopamine; Electroshock; gamma-Aminobutyric Acid; Male; Methyltyrosines; Rats; Rats, Inbred Strains; Thyrotropin-Releasing Hormone

1983
Thyrotropin releasing hormone stimulation of GABA-gated but not basal chloride ion influx in rat cerebellum.
    Peptides, 1999, Volume: 20, Issue:11

    Topics: Animals; Cerebellum; Chlorides; gamma-Aminobutyric Acid; Ion Channel Gating; Male; Rats; Rats, Sprague-Dawley; Synaptosomes; Thyrotropin-Releasing Hormone

1999