Page last updated: 2024-09-04

dmp 450 and saquinavir

dmp 450 has been researched along with saquinavir in 3 studies

Compound Research Comparison

Studies
(dmp 450)
Trials
(dmp 450)
Recent Studies (post-2010)
(dmp 450)
Studies
(saquinavir)
Trials
(saquinavir)
Recent Studies (post-2010) (saquinavir)
23011,454256219

Protein Interaction Comparison

ProteinTaxonomydmp 450 (IC50)saquinavir (IC50)
Voltage-dependent L-type calcium channel subunit alpha-1FHomo sapiens (human)1.9
Bile salt export pumpHomo sapiens (human)3.9
Gag-Pol polyproteinHuman immunodeficiency virus type 1 (BRU ISOLATE)0.016
Gag-Pol polyproteinHuman immunodeficiency virus type 2 (ISOLATE ROD)0.0084
Gag polyproteinHIV-1 M:B_MN0.0131
ATP-dependent translocase ABCB1Homo sapiens (human)4.05
Cytochrome P450 3A4Homo sapiens (human)1.5
Gag-Pol polyproteinHuman immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)0.0066
5-hydroxytryptamine receptor 1ARattus norvegicus (Norway rat)4.273
Substance-K receptorHomo sapiens (human)6.214
Thromboxane-A synthase Homo sapiens (human)2.182
5-hydroxytryptamine receptor 1BRattus norvegicus (Norway rat)4.273
Mu-type opioid receptorHomo sapiens (human)9.625
Kappa-type opioid receptorHomo sapiens (human)6.951
Exoribonuclease H Human immunodeficiency virus 20.0005
Voltage-dependent L-type calcium channel subunit alpha-1D Homo sapiens (human)1.9
Voltage-dependent L-type calcium channel subunit alpha-1SHomo sapiens (human)1.9
Voltage-dependent L-type calcium channel subunit alpha-1CHomo sapiens (human)1.9
Genome polyprotein Human rhinovirus sp.0.0005
Solute carrier family 22 member 1Rattus norvegicus (Norway rat)8.26
Protease Human immunodeficiency virus 10.0217
Protease Human immunodeficiency virus 10.0004

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (100.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ala, P; Anton, ED; Bacheler, LT; Chang, CH; Garber, SS; Jadhav, PK; Woerner, FJ1
Cheatham, WW; Dax, S; Wilkerson, WW1
Anderson, PS; Bacheler, LT; Chang, CH; Cordova, B; Erickson-Viitanen, S; Garber, S; Johnson, BL; Klabe, RM; Ko, SS; Lam, PY; Li, R; Reid, C; Rodgers, JD; Ru, Y; Seitz, SP; Trainor, GL; Wang, H; Wright, MR1

Other Studies

3 other study(ies) available for dmp 450 and saquinavir

ArticleYear
Cyclic urea amides: HIV-1 protease inhibitors with low nanomolar potency against both wild type and protease inhibitor resistant mutants of HIV.
    Journal of medicinal chemistry, 1997, Jan-17, Volume: 40, Issue:2

    Topics: Amides; Anti-HIV Agents; Cells, Cultured; Crystallography, X-Ray; Drug Resistance, Microbial; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Mutation; Protein Conformation; Sensitivity and Specificity; Urea

1997
Nonsymmetrically substituted cyclic urea HIV protease inhibitors.
    Journal of medicinal chemistry, 1997, Dec-05, Volume: 40, Issue:25

    Topics: Anti-HIV Agents; HIV Protease Inhibitors; RNA, Viral; Structure-Activity Relationship; Urea

1997
Design and selection of DMP 850 and DMP 851: the next generation of cyclic urea HIV protease inhibitors.
    Chemistry & biology, 1998, Volume: 5, Issue:10

    Topics: Animals; Anti-HIV Agents; Crystallography, X-Ray; Dogs; Drug Design; HIV; HIV Protease Inhibitors; Molecular Structure; Mutation; Protein Binding; Urea; Virus Replication

1998