dmp 450 and amprenavir
dmp 450 has been researched along with amprenavir in 4 studies
Compound Research Comparison
Studies (dmp 450) | Trials (dmp 450) | Recent Studies (post-2010) (dmp 450) | Studies (amprenavir) | Trials (amprenavir) | Recent Studies (post-2010) (amprenavir) |
---|---|---|---|---|---|
23 | 0 | 1 | 555 | 91 | 94 |
Protein Interaction Comparison
Protein | Taxonomy | dmp 450 (IC50) | amprenavir (IC50) |
---|---|---|---|
Gag-Pol polyprotein | Human immunodeficiency virus type 1 (BRU ISOLATE) | 0.027 | |
Gag-Pol polyprotein | Human immunodeficiency virus type 2 (ISOLATE ROD) | 0.0026 | |
Gag polyprotein | HIV-1 M:B_MN | 0.013 | |
Cytochrome P450 3A4 | Homo sapiens (human) | 1 | |
Gag-Pol polyprotein | Human immunodeficiency virus type 1 (NEW YORK-5 ISOLATE) | 0.0558 | |
Thromboxane-A synthase | Homo sapiens (human) | 6.727 | |
Protease | Human immunodeficiency virus 1 | 0.1553 |
Research
Studies (4)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 3 (75.00) | 18.2507 |
2000's | 1 (25.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Ala, P; Anton, ED; Bacheler, LT; Chang, CH; Garber, SS; Jadhav, PK; Woerner, FJ | 1 |
Cheatham, WW; Dax, S; Wilkerson, WW | 1 |
Anderson, PS; Bacheler, LT; Chang, CH; Cordova, B; Erickson-Viitanen, S; Garber, S; Johnson, BL; Klabe, RM; Ko, SS; Lam, PY; Li, R; Reid, C; Rodgers, JD; Ru, Y; Seitz, SP; Trainor, GL; Wang, H; Wright, MR | 1 |
Aungst, BJ; Bulgarelli, JP; Nguyen, NH; Oates-Lenz, K | 1 |
Other Studies
4 other study(ies) available for dmp 450 and amprenavir
Article | Year |
---|---|
Cyclic urea amides: HIV-1 protease inhibitors with low nanomolar potency against both wild type and protease inhibitor resistant mutants of HIV.
Topics: Amides; Anti-HIV Agents; Cells, Cultured; Crystallography, X-Ray; Drug Resistance, Microbial; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Mutation; Protein Conformation; Sensitivity and Specificity; Urea | 1997 |
Nonsymmetrically substituted cyclic urea HIV protease inhibitors.
Topics: Anti-HIV Agents; HIV Protease Inhibitors; RNA, Viral; Structure-Activity Relationship; Urea | 1997 |
Design and selection of DMP 850 and DMP 851: the next generation of cyclic urea HIV protease inhibitors.
Topics: Animals; Anti-HIV Agents; Crystallography, X-Ray; Dogs; Drug Design; HIV; HIV Protease Inhibitors; Molecular Structure; Mutation; Protein Binding; Urea; Virus Replication | 1998 |
The influence of donor and reservoir additives on Caco-2 permeability and secretory transport of HIV protease inhibitors and other lipophilic compounds.
Topics: Acetamides; Albumins; Azepines; Caco-2 Cells; Carbamates; Cell Membrane Permeability; Furans; HIV Protease Inhibitors; Humans; Indinavir; Intestinal Absorption; Nelfinavir; Ritonavir; Solvents; Structure-Activity Relationship; Sulfonamides; Urea | 2000 |