Page last updated: 2024-09-04

dmp 450 and amprenavir

dmp 450 has been researched along with amprenavir in 4 studies

Compound Research Comparison

Studies
(dmp 450)
Trials
(dmp 450)
Recent Studies (post-2010)
(dmp 450)
Studies
(amprenavir)
Trials
(amprenavir)
Recent Studies (post-2010) (amprenavir)
23015559194

Protein Interaction Comparison

ProteinTaxonomydmp 450 (IC50)amprenavir (IC50)
Gag-Pol polyproteinHuman immunodeficiency virus type 1 (BRU ISOLATE)0.027
Gag-Pol polyproteinHuman immunodeficiency virus type 2 (ISOLATE ROD)0.0026
Gag polyproteinHIV-1 M:B_MN0.013
Cytochrome P450 3A4Homo sapiens (human)1
Gag-Pol polyproteinHuman immunodeficiency virus type 1 (NEW YORK-5 ISOLATE)0.0558
Thromboxane-A synthase Homo sapiens (human)6.727
Protease Human immunodeficiency virus 10.1553

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (75.00)18.2507
2000's1 (25.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ala, P; Anton, ED; Bacheler, LT; Chang, CH; Garber, SS; Jadhav, PK; Woerner, FJ1
Cheatham, WW; Dax, S; Wilkerson, WW1
Anderson, PS; Bacheler, LT; Chang, CH; Cordova, B; Erickson-Viitanen, S; Garber, S; Johnson, BL; Klabe, RM; Ko, SS; Lam, PY; Li, R; Reid, C; Rodgers, JD; Ru, Y; Seitz, SP; Trainor, GL; Wang, H; Wright, MR1
Aungst, BJ; Bulgarelli, JP; Nguyen, NH; Oates-Lenz, K1

Other Studies

4 other study(ies) available for dmp 450 and amprenavir

ArticleYear
Cyclic urea amides: HIV-1 protease inhibitors with low nanomolar potency against both wild type and protease inhibitor resistant mutants of HIV.
    Journal of medicinal chemistry, 1997, Jan-17, Volume: 40, Issue:2

    Topics: Amides; Anti-HIV Agents; Cells, Cultured; Crystallography, X-Ray; Drug Resistance, Microbial; HIV Protease; HIV Protease Inhibitors; HIV-1; Humans; Mutation; Protein Conformation; Sensitivity and Specificity; Urea

1997
Nonsymmetrically substituted cyclic urea HIV protease inhibitors.
    Journal of medicinal chemistry, 1997, Dec-05, Volume: 40, Issue:25

    Topics: Anti-HIV Agents; HIV Protease Inhibitors; RNA, Viral; Structure-Activity Relationship; Urea

1997
Design and selection of DMP 850 and DMP 851: the next generation of cyclic urea HIV protease inhibitors.
    Chemistry & biology, 1998, Volume: 5, Issue:10

    Topics: Animals; Anti-HIV Agents; Crystallography, X-Ray; Dogs; Drug Design; HIV; HIV Protease Inhibitors; Molecular Structure; Mutation; Protein Binding; Urea; Virus Replication

1998
The influence of donor and reservoir additives on Caco-2 permeability and secretory transport of HIV protease inhibitors and other lipophilic compounds.
    Pharmaceutical research, 2000, Volume: 17, Issue:10

    Topics: Acetamides; Albumins; Azepines; Caco-2 Cells; Carbamates; Cell Membrane Permeability; Furans; HIV Protease Inhibitors; Humans; Indinavir; Intestinal Absorption; Nelfinavir; Ritonavir; Solvents; Structure-Activity Relationship; Sulfonamides; Urea

2000
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