dl 111-it has been researched along with triazoles in 36 studies
| Studies (dl 111-it) | Trials (dl 111-it) | Recent Studies (post-2010) (dl 111-it) | Studies (triazoles) | Trials (triazoles) | Recent Studies (post-2010) (triazoles) |
|---|---|---|---|---|---|
| 38 | 0 | 1 | 25,808 | 2,252 | 13,501 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (36.11) | 18.7374 |
| 1990's | 6 (16.67) | 18.2507 |
| 2000's | 16 (44.44) | 29.6817 |
| 2010's | 1 (2.78) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fang, RY; Yang, BZ; Zhang, YP; Zhou, HJ | 1 |
| Prasad, RS; Vijayan, E | 2 |
| Assandri, A; Barone, D; Colombo, G; Conz, A; Galliani, G; Lancini, GC; Luzzani, F; Mistrello, L | 1 |
| Lin, ZY; Liu, ZQ; Sun, L; Yu, YN | 1 |
| Lerner, LJ | 1 |
| Cai, Y; Chen, YT; Jiao, J; Lin, ZY; Liu, ZQ | 1 |
| Assandri, A; Bassi, L; Filippeschi, S; Galliani, G; Mistrello, G | 1 |
| Assandri, A; Ferrari, P; Galliani, G; Omodei-Salé, A; Perazzi, A; Ripamonti, A; Tuan, G; Zerilli, LF | 1 |
| Assandri, A; Galliani, G; Omodei-Salé, A; Perazzi, A; Sartori, G | 1 |
| Consonni, P; Galliani, G; Omodei-Salé, A | 1 |
| Assandri, A; Galliani, G; Grant, AM; Lancini, G; Lerner, LJ; Nock, PE; Omodei-Salè, A | 1 |
| Assandri, A; Galliani, G; Gallico, L; Lancini, G; Luzzani, F; Oldani, C; Omodei-Salè, A; Soffientini, A | 1 |
| Galliani, G; Luzzani, F | 1 |
| Fan, CM; Fang, XC; Li, ZX; Luo, WY; Ying, Y; Zhou, JH | 1 |
| Fang, RY; Yang, B | 1 |
| Cao, L; Fang, RY; Gu, ZP; Yang, B | 1 |
| Farheen, S; Jaggi, M; Mehrotra, PK | 1 |
| Bo, Y; Lin, C; Ruiying, F; Zhiping, G | 1 |
| Fang, RY; He, QJ; Yang, B; Ying, Y | 1 |
| Fang, RY; He, QJ; Yang, B; Zhou, HJ | 1 |
| Fang, R; He, Q; Shentu, J; Wang, L; Zhou, H | 1 |
| Hu, Y; Liu, T | 1 |
| Hu, YZ; Yao, TW | 4 |
| Wang, X; Yao, T; Zeng, S | 1 |
| Fang, RY; He, QJ; Wang, WF; Wu, HH; Yang, B | 1 |
| Aglianò, M; Carminati, P; Lorenzoni, P; Pacifici, L; Ruggiero, V; Sorrentino, V; Stasi, MA; Taurelli, R; Ursillo, A; Weber, E | 1 |
| Azzollini, N; Carminati, P; Cassis, L; Cravedi, P; DeSantis, R; Mister, M; Noris, M; Pezzotta, A; Remuzzi, G; Ruggiero, V | 1 |
| Fang, RY; He, QJ; Lou, YJ; Yang, B; Zhu, DY | 1 |
| Fang, RY; He, QJ; Lou, YJ; Yang, B | 1 |
| Arseni, B; Campo, S; Capuani, G; Carminati, P; Colafranceschi, M; Conti, F; De Santis, R; Giuliani, A; Miccheli, A; Rossi, S; Ruggiero, V; Tomassini, A; Valerio, M | 1 |
| Ahl, PL; Arseni, B; Battistini, L; Bonitz, S; Campo, S; Carminati, P; D'Alessio, V; De Santis, R; Di Mitri, D; Lu, R; Mannino, R; Ngoje, J; Rossi, S; Ruggiero, V | 1 |
| Arseni, B; Campo, S; D'Alessio, V; De Santis, R; Loiarro, M; Rossi, S; Ruggiero, V; Sette, C | 1 |
36 other study(ies) available for dl 111-it and triazoles
| Article | Year |
|---|---|
Embryotoxicity and teratogenicity of DL111-IT, an early pregnancy-terminating agent, in the subsequent gestation following administration in rats.
Topics: Abnormalities, Drug-Induced; Abortifacient Agents, Nonsteroidal; Animals; Embryonic and Fetal Development; Female; Incidence; Injections, Subcutaneous; Male; Mice; Pregnancy; Pregnancy, Animal; Rats; Rats, Inbred Strains; Triazoles | 1991 |
A new non-hormonal antifertility drug DL 111-IT: I. Effects on testes and accessory glands of reproduction in male rats.
Topics: Abortifacient Agents; Abortifacient Agents, Nonsteroidal; Animals; Body Weight; DNA; Epididymis; Genitalia, Male; Male; Organ Size; Prostate; Proteins; Rats; Rats, Inbred Strains; RNA; Seminal Vesicles; Sexual Maturation; Testis; Triazoles | 1986 |
On the mode of action of a new contragestational agent (DL 111-IT).
Topics: Abortifacient Agents, Nonsteroidal; Animals; Cricetinae; Decidua; DNA; Female; Follicle Stimulating Hormone; Glucosephosphate Dehydrogenase; Lactates; Lactic Acid; Luteinizing Hormone; Mesocricetus; Ornithine Decarboxylase; Placenta; Pregnancy; Prolactin; Protein Biosynthesis; Rats; Rats, Inbred Strains; Receptors, Progesterone; Regional Blood Flow; RNA; Triazoles; Uterus | 1986 |
[Selective inducing ability of DL-111-1T towards mixed function oxidase in female rat liver and human amnion fluid cell].
Topics: Abortifacient Agents; Abortifacient Agents, Nonsteroidal; Amnion; Animals; Aryl Hydrocarbon Hydroxylases; Cells, Cultured; Dose-Response Relationship, Drug; Female; Microsomes, Liver; Mixed Function Oxygenases; Rats; Rats, Inbred Strains; Triazoles | 1989 |
Development of novel embryotoxic compounds for interceptive fertility control in the dog.
Topics: Abortifacient Agents; Abortifacient Agents, Nonsteroidal; Animals; Cricetinae; Dogs; Dose-Response Relationship, Drug; Female; Guinea Pigs; Indoles; Isoindoles; Isoquinolines; Pregnancy; Pregnancy, Animal; Rats; Time Factors; Triazoles | 1989 |
[A new polycyclic arylhydrocarbon type inducer of drug metabolizing enzymes--the contragestational agent DL-111-IT].
Topics: Abortifacient Agents; Abortifacient Agents, Nonsteroidal; Animals; Arabidopsis Proteins; Benzopyrene Hydroxylase; Cytochrome P-450 Enzyme System; Glucosyltransferases; Liver; Male; Mice; Mice, Inbred BALB C; Microsomes, Liver; Rats; Rats, Inbred Strains; Triazoles | 1987 |
A new non-hormonal antifertility drug DL 111-IT: II. Effects on testicular hyaluronidase activity in male rats.
Topics: Abortifacient Agents; Abortifacient Agents, Nonsteroidal; Aging; Animals; Follicle Stimulating Hormone; Gonadotropins, Equine; Hyaluronoglucosaminidase; Kinetics; Luteinizing Hormone; Male; Rats; Rats, Inbred Strains; Sexual Maturation; Testis; Testosterone; Triazoles | 1986 |
Immunological profile of DL111-IT, a new immunosuppressant agent.
Topics: Animals; Antibody Formation; Dose-Response Relationship, Drug; Hypersensitivity, Delayed; Immunosuppressive Agents; Inflammation; Lymphoma; Male; Neoplasms, Experimental; Rats; Rats, Inbred Strains; Triazoles | 1985 |
Metabolic pathways of the contragestational agent, 3-(2-ethylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazole (DL 111-IT), in the rat.
Topics: Abortifacient Agents; Animals; Bile; Chemical Phenomena; Chemistry; Feces; Female; Magnetic Resonance Spectroscopy; Pregnancy; Rats; Rats, Inbred Strains; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Triazoles | 1984 |
Pharmacokinetics-activity relationships of a new non-hormonal antifertility agent: 3-(2-ethylphenyl)-5-(3-methoxyphenyl)-1H-1, 2,4-triazole, in the rat and the hamster.
Topics: Animals; Contraceptives, Oral; Cricetinae; Female; Fertility; Half-Life; Kinetics; Mesocricetus; Pregnancy; Protein Binding; Rats; Rats, Inbred Strains; Species Specificity; Tissue Distribution; Triazoles | 1983 |
A new class of nonhormonal pregnancy-terminating agents. Synthesis and contragestational activity of 3,5-diaryl-s-triazoles.
Topics: Abortifacient Agents; Abortifacient Agents, Nonsteroidal; Animals; Cricetinae; Female; Pregnancy; Rats; Structure-Activity Relationship; Triazoles | 1983 |
DL 111, a new non-hormonal antifertility agent: contragestational and kinetic profile in baboons.
Topics: Abortifacient Agents; Animals; Female; Fetus; Gestational Age; Kinetics; Male; Menstruation; Papio; Pregnancy; Progesterone; Triazoles | 1982 |
A new non-hormonal pregnancy-terminating agent.
Topics: Abortifacient Agents; Abortifacient Agents, Nonsteroidal; Adrenalectomy; Animals; Castration; Cricetinae; Dogs; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Female; Hypophysectomy; Mice; Pregnancy; Pregnancy, Animal; Progesterone; Rats; Triazoles | 1981 |
On the mechanism of action of a new pregnancy-terminating agent. Part I: Effects of prostaglandin F2 alpha metabolism in the rat and the hamster.
Topics: Abortifacient Agents; Animals; Cricetinae; Female; Lung; Placenta; Pregnancy; Prostaglandins F; Rats; Triazoles; Uterus | 1981 |
[Pharmacokinetics of contragestazol (DL-111-IT), a new non-steroid antifertility agent in monkeys].
Topics: Abortifacient Agents, Nonsteroidal; Animals; Chromatography, High Pressure Liquid; Female; Macaca mulatta; Male; Triazoles | 1995 |
Synergistic effects on pregnancy-termination activity of DL111-IT in combination with mifepristone.
Topics: Abortifacient Agents, Nonsteroidal; Abortifacient Agents, Steroidal; Abortion, Induced; Animals; Cells, Cultured; Decidua; Drug Synergism; Female; Humans; Mifepristone; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Progesterone; Triazoles; Uterus | 1996 |
Effect of DL111-IT on progesterone biosynthesis and viability of rat luteal cells in vitro.
Topics: Abortifacient Agents, Nonsteroidal; Animals; Cell Survival; Cells, Cultured; Colforsin; Female; Luteal Cells; Pregnenolone; Progesterone; Rats; Rats, Sprague-Dawley; Triazoles | 1997 |
Use of differentiating human trophoblasts in in vitro assay.
Topics: Abortifacient Agents, Nonsteroidal; Adult; Cell Culture Techniques; Cell Differentiation; Cells, Cultured; Female; Heterocyclic Compounds; Humans; Triazoles; Trophoblasts | 1999 |
Luteolytic effects of DL111-IT in pregnant rats.
Topics: 20-alpha-Hydroxysteroid Dehydrogenase; 20-Hydroxysteroid Dehydrogenases; 3-Hydroxysteroid Dehydrogenases; Abortifacient Agents, Nonsteroidal; Animals; Corpus Luteum; DNA; Female; Histocytochemistry; Luteolytic Agents; Male; Nucleosomes; Organ Size; Ovary; Pregnancy; Progesterone; Proteins; Rats; Rats, Sprague-Dawley; Triazoles | 1999 |
Synergistic effects of DL111-IT combined with mifepristone on termination of early pregnancy in rhesus monkeys.
Topics: Abortifacient Agents, Nonsteroidal; Abortion, Induced; Abortion, Veterinary; Animals; Drug Synergism; Female; Macaca mulatta; Male; Mifepristone; Pregnancy; Triazoles | 2000 |
Termination of early pregnancy in the mouse, rat and hamster with DL111-IT and RU486.
Topics: Abortifacient Agents, Nonsteroidal; Abortion, Induced; Abortion, Veterinary; Animals; Cricetinae; Female; Male; Mesocricetus; Mice; Mifepristone; Pregnancy; Rats; Rats, Sprague-Dawley; Triazoles | 2000 |
Effects of DL111-IT or combined with RU486 on uterine polyamines biosynthesis in rats during early gestation.
Topics: Abortifacient Agents, Nonsteroidal; Abortifacient Agents, Steroidal; Abortion, Induced; Animals; Biogenic Polyamines; Decidua; Female; Histocytochemistry; Male; Mifepristone; Pregnancy; Random Allocation; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Triazoles; Uterus | 2001 |
Non-steroidal pregnancy-terminating agents: design, synthesis and structure-activity relationships of 2-aryl-1,2,4-triazolo[1,5-a]pyridine.
Topics: Abortifacient Agents, Nonsteroidal; Animals; Drug Design; Embryo Implantation; Embryo, Mammalian; Luteolysis; Luteolytic Agents; Mice; Pyridines; Structure-Activity Relationship; Triazoles | 2002 |
[RP-HPLC determination of diphenytriazol in rat liver microsomal incubates and its application in in vitro metabolism].
Topics: Abortifacient Agents, Nonsteroidal; Animals; Cell Separation; Chromatography, High Pressure Liquid; Female; Microsomes, Liver; Rats; Rats, Sprague-Dawley; Triazoles | 2002 |
Determination of diphenytriazol (DL111-IT) and its related impurities by RP-HPLC with DAD.
Topics: Chromatography, High Pressure Liquid; Drug Contamination; Triazoles | 2003 |
Synergistic effects of DL111-IT in combination with mifepristone and misoprostol on termination of early pregnancy in preclinical studies.
Topics: Abortifacient Agents, Nonsteroidal; Abortifacient Agents, Steroidal; Abortion, Induced; Animals; Columbidae; Drug Synergism; Drug Therapy, Combination; Female; Guinea Pigs; Male; Mice; Mifepristone; Misoprostol; Pregnancy; Pregnancy Trimester, First; Rats; Rats, Sprague-Dawley; Triazoles; Uterus; Vomiting | 2003 |
In vitro metabolism and inductive or inhibitive effect of DL111 on rat cytochrome P4501A enzyme.
Topics: Abortifacient Agents, Nonsteroidal; Animals; beta-Naphthoflavone; Chromatography, High Pressure Liquid; Cytochrome P-450 CYP1A1; Dexamethasone; Dose-Response Relationship, Drug; Drug Therapy, Combination; Enzyme Induction; Enzyme Inhibitors; Female; Microsomes, Liver; Phenobarbital; Rats; Rats, Sprague-Dawley; Triazoles | 2004 |
Induction of diphenytriazol on cytochrome CYP1A.
Topics: Abortifacient Agents, Nonsteroidal; Aminopyrine; Animals; Benzoflavones; beta-Naphthoflavone; Cytochrome P-450 CYP1A1; Cytochrome P-450 CYP2B1; Female; Fluvoxamine; Microsomes, Liver; Phenacetin; Rats; Rats, Sprague-Dawley; Triazoles | 2004 |
Ameliorating effects of the immunomodulator 3-(2-ethylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazole in an experimental model of colitis in the rat.
Topics: Animals; Body Weight; Colitis; Colon; Cytokines; Diarrhea; Immunohistochemistry; Immunosuppressive Agents; Male; Neutrophil Infiltration; Organ Size; Peroxidase; Rats; Rats, Sprague-Dawley; Triazoles; Trinitrobenzenesulfonic Acid | 2004 |
Effect of a novel immunosuppressant, ST1959, on the immune system and renal allograft survival in rats.
Topics: Animals; Graft Survival; Immunosuppressive Agents; Kidney Transplantation; Lymph Nodes; Male; Organ Size; Rats; Rats, Inbred BN; Rats, Inbred Lew; Spleen; T-Lymphocyte Subsets; Transplantation, Homologous; Triazoles | 2005 |
Antiproliferative activity of contragestazol (DL111-IT) in murine and human tumor models in vitro and in vivo.
Topics: Animals; Carcinoma, Hepatocellular; Cell Cycle; Cell Proliferation; Female; Flow Cytometry; Gene Expression Profiling; Humans; Liver Neoplasms; Mice; Mice, Inbred BALB C; Sarcoma; Transplantation, Heterologous; Triazoles; Tumor Cells, Cultured | 2006 |
Contragestazol (DL111-IT) inhibits proliferation of human androgen-independent prostate cancer cell line PC3 in vitro and in vivo.
Topics: Androgens; Animals; Cell Division; Cell Line, Tumor; Cyclin D1; Cyclin-Dependent Kinase 4; Dose-Response Relationship, Drug; Female; G1 Phase; Humans; Immunosuppressive Agents; In Vitro Techniques; Male; Mice; Mice, Inbred BALB C; Mice, Nude; Neoplasm Transplantation; Prostatic Neoplasms; Resting Phase, Cell Cycle; Retinoblastoma Protein; Transplantation, Heterologous; Triazoles | 2005 |
[In vitro metabolic interaction between diphenytriazol and steroid hormone drugs].
Topics: Abortifacient Agents, Nonsteroidal; Abortifacient Agents, Steroidal; Animals; Contraceptives, Oral, Synthetic; Drug Interactions; Estradiol; Female; In Vitro Techniques; Medroxyprogesterone; Microsomes, Liver; Mifepristone; Rats; Rats, Sprague-Dawley; Triazoles | 2006 |
Dissecting drug and vehicle metabolic effects in rats by a metabonomic approach.
Topics: Algorithms; Animals; Glucose; Liver; Magnetic Resonance Spectroscopy; Male; Multivariate Analysis; Pattern Recognition, Automated; Pharmaceutical Preparations; Pharmaceutical Vehicles; Rats; Rats, Inbred Lew; Sesame Oil; Triazoles | 2007 |
Efficacy of a nanocochleate-encapsulated 3,5-diaryl-s-triazole derivative in a murine model of graft-versus-host disease.
Topics: Administration, Oral; Anemia; Animals; CD4-Positive T-Lymphocytes; CD8-Positive T-Lymphocytes; Chemokines; Disease Models, Animal; Drug Compounding; Female; Graft vs Host Disease; Hematologic Tests; Immunosuppressive Agents; Mice; Mice, Inbred C57BL; Nanocapsules; Time Factors; Triazoles | 2008 |
Anti-proliferative effect of a triazole derivative (ST1959) on LNCaP human prostate cancer cells through down-regulation of cyclin and androgen receptor expression.
Topics: Adenocarcinoma; Cell Line, Tumor; Cell Proliferation; Cyclins; Down-Regulation; Gene Expression Regulation, Neoplastic; Humans; Immunosuppressive Agents; Male; Prostatic Neoplasms; Receptors, Androgen; Triazoles | 2011 |