dl 111-it has been researched along with mifepristone in 6 studies
| Studies (dl 111-it) | Trials (dl 111-it) | Recent Studies (post-2010) (dl 111-it) | Studies (mifepristone) | Trials (mifepristone) | Recent Studies (post-2010) (mifepristone) |
|---|---|---|---|---|---|
| 38 | 0 | 1 | 6,536 | 595 | 1,758 |
| Protein | Taxonomy | dl 111-it (IC50) | mifepristone (IC50) |
|---|---|---|---|
| Glucocorticoid receptor | Canis lupus familiaris (dog) | 0.0264 | |
| Bile salt export pump | Homo sapiens (human) | 2.02 | |
| Estrogen receptor | Homo sapiens (human) | 4.311 | |
| Glucocorticoid receptor | Homo sapiens (human) | 0.0249 | |
| Prostaglandin G/H synthase 1 | Ovis aries (sheep) | 0.0003 | |
| Progesterone receptor | Homo sapiens (human) | 0.1347 | |
| Glucocorticoid receptor | Rattus norvegicus (Norway rat) | 0.774 | |
| Glucocorticoid receptor | Mus musculus (house mouse) | 0.0022 | |
| Glycine receptor subunit alpha-1 | Rattus norvegicus (Norway rat) | 0.0022 | |
| Mineralocorticoid receptor | Homo sapiens (human) | 2.0938 | |
| Cytochrome P450 3A4 | Homo sapiens (human) | 9.5 | |
| Coagulation factor VII | Homo sapiens (human) | 0.0003 | |
| Androgen receptor | Homo sapiens (human) | 0.2988 | |
| Cytochrome P450 2C8 | Homo sapiens (human) | 1.5 | |
| Cytochrome P450 2C9 | Homo sapiens (human) | 4.9 | |
| Steroid 17-alpha-hydroxylase/17,20 lyase | Rattus norvegicus (Norway rat) | 0.0016 | |
| Polyunsaturated fatty acid lipoxygenase ALOX15 | Oryctolagus cuniculus (rabbit) | 0.555 | |
| Tissue factor | Homo sapiens (human) | 0.0003 | |
| Androgen receptor | Rattus norvegicus (Norway rat) | 0.0083 | |
| 5-hydroxytryptamine receptor 1A | Rattus norvegicus (Norway rat) | 0.0014 | |
| Glycine receptor subunit beta | Rattus norvegicus (Norway rat) | 0.0022 | |
| Glycine receptor subunit alpha-2 | Rattus norvegicus (Norway rat) | 0.0022 | |
| Prostaglandin G/H synthase 1 | Homo sapiens (human) | 0.0078 | |
| Glycine receptor subunit alpha-3 | Rattus norvegicus (Norway rat) | 0.0022 | |
| Substance-P receptor | Cavia porcellus (domestic guinea pig) | 0.0015 | |
| Mu-type opioid receptor | Homo sapiens (human) | 2.457 | |
| Estrogen receptor beta | Homo sapiens (human) | 1.528 | |
| Glucocorticoid receptor | Sus scrofa (pig) | 0.0153 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (16.67) | 18.2507 |
| 2000's | 5 (83.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fang, RY; Yang, B | 1 |
| Fang, RY; He, QJ; Yang, B; Ying, Y | 1 |
| Fang, RY; He, QJ; Yang, B; Zhou, HJ | 1 |
| Fang, R; He, Q; Shentu, J; Wang, L; Zhou, H | 1 |
| Fang, RY; He, QJ; Wang, WF; Wu, HH; Yang, B | 1 |
| Hu, YZ; Yao, TW | 1 |
6 other study(ies) available for dl 111-it and mifepristone
| Article | Year |
|---|---|
Synergistic effects on pregnancy-termination activity of DL111-IT in combination with mifepristone.
Topics: Abortifacient Agents, Nonsteroidal; Abortifacient Agents, Steroidal; Abortion, Induced; Animals; Cells, Cultured; Decidua; Drug Synergism; Female; Humans; Mifepristone; Pregnancy; Rats; Rats, Sprague-Dawley; Receptors, Progesterone; Triazoles; Uterus | 1996 |
Synergistic effects of DL111-IT combined with mifepristone on termination of early pregnancy in rhesus monkeys.
Topics: Abortifacient Agents, Nonsteroidal; Abortion, Induced; Abortion, Veterinary; Animals; Drug Synergism; Female; Macaca mulatta; Male; Mifepristone; Pregnancy; Triazoles | 2000 |
Termination of early pregnancy in the mouse, rat and hamster with DL111-IT and RU486.
Topics: Abortifacient Agents, Nonsteroidal; Abortion, Induced; Abortion, Veterinary; Animals; Cricetinae; Female; Male; Mesocricetus; Mice; Mifepristone; Pregnancy; Rats; Rats, Sprague-Dawley; Triazoles | 2000 |
Effects of DL111-IT or combined with RU486 on uterine polyamines biosynthesis in rats during early gestation.
Topics: Abortifacient Agents, Nonsteroidal; Abortifacient Agents, Steroidal; Abortion, Induced; Animals; Biogenic Polyamines; Decidua; Female; Histocytochemistry; Male; Mifepristone; Pregnancy; Random Allocation; Rats; Rats, Sprague-Dawley; Statistics, Nonparametric; Triazoles; Uterus | 2001 |
Synergistic effects of DL111-IT in combination with mifepristone and misoprostol on termination of early pregnancy in preclinical studies.
Topics: Abortifacient Agents, Nonsteroidal; Abortifacient Agents, Steroidal; Abortion, Induced; Animals; Columbidae; Drug Synergism; Drug Therapy, Combination; Female; Guinea Pigs; Male; Mice; Mifepristone; Misoprostol; Pregnancy; Pregnancy Trimester, First; Rats; Rats, Sprague-Dawley; Triazoles; Uterus; Vomiting | 2003 |
[In vitro metabolic interaction between diphenytriazol and steroid hormone drugs].
Topics: Abortifacient Agents, Nonsteroidal; Abortifacient Agents, Steroidal; Animals; Contraceptives, Oral, Synthetic; Drug Interactions; Estradiol; Female; In Vitro Techniques; Medroxyprogesterone; Microsomes, Liver; Mifepristone; Rats; Rats, Sprague-Dawley; Triazoles | 2006 |