dizocilpine-maleate and fluperlapine

dizocilpine-maleate has been researched along with fluperlapine* in 1 studies

Other Studies

1 other study(ies) available for dizocilpine-maleate and fluperlapine

Article	Year
Olanzapine and fluperlapine mimic clozapine in preventing MK-801 neurotoxicity. Schizophrenia research, 1996, Volume: 21, Issue:1 Antagonists of the N-methyl-D-Aspartate (NMDA) subtype of glutamate receptor (e.g., phencyclidine, ketamine, MK-801) cause a schizophrenia-like psychosis in humans and neurotoxicity in the adult rat brain. We report here that clozapine and structurally related agents (olanzapine, fluperlapine, loxapine, amoxapine) can prevent NMDA antagonist neurotoxicity in the rat with a rank order corresponding to their ability to mimic the antipsychotic properties of clozapine. Topics: Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzazepines; Dibenzoxazepines; Dizocilpine Maleate; Female; N-Methylaspartate; Nervous System; Olanzapine; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate	1996

Article

Year

Olanzapine and fluperlapine mimic clozapine in preventing MK-801 neurotoxicity.

Schizophrenia research, 1996, Volume: 21, Issue:1

Antagonists of the N-methyl-D-Aspartate (NMDA) subtype of glutamate receptor (e.g., phencyclidine, ketamine, MK-801) cause a schizophrenia-like psychosis in humans and neurotoxicity in the adult rat brain. We report here that clozapine and structurally related agents (olanzapine, fluperlapine, loxapine, amoxapine) can prevent NMDA antagonist neurotoxicity in the rat with a rank order corresponding to their ability to mimic the antipsychotic properties of clozapine.

Topics: Animals; Antipsychotic Agents; Benzodiazepines; Clozapine; Dibenzazepines; Dibenzoxazepines; Dizocilpine Maleate; Female; N-Methylaspartate; Nervous System; Olanzapine; Pirenzepine; Rats; Rats, Sprague-Dawley; Receptors, N-Methyl-D-Aspartate

1996