dizocilpine-maleate and 1--2--dihydrorotenone

dizocilpine-maleate has been researched along with 1--2--dihydrorotenone* in 1 studies

Other Studies

1 other study(ies) available for dizocilpine-maleate and 1--2--dihydrorotenone

Article	Year
Autoradiographic study of mitochondrial complex I and glutamate receptors in the basal ganglia of rats after unilateral subthalamic lesion. Neuroscience letters, 1995, Feb-17, Volume: 186, Issue:2-3 A unilateral lesion of the subthalamic nucleus (STN) induced, in the short-term (< or = 1 week), an ipsilateral decrease in [3H]dihydrorotenone binding to complex I in entopeduncular nucleus and substantia nigra pars reticulata (SNr). A slight reduction of [3H]MK-801 binding to N-methyl-D-aspartate (NMDA) receptors in the ipsilateral SNr was also found, whereas no changes in [3H]alpha-amino-3-hydroxy-5-methylisoxazole propionic acid binding were observed. The complex I decrease likely reflects a reduction in neuronal activity subsequent to the interruption of excitatory signaling from STN. The unexpected decrease in [3H]MK-801 binding in SNr may be related to presynaptic NMDA receptor modifications. Topics: Animals; Autoradiography; Basal Ganglia; Dizocilpine Maleate; Histocytochemistry; Male; Mitochondria; NAD(P)H Dehydrogenase (Quinone); Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Rotenone; Thalamic Nuclei	1995

Article

Year

Autoradiographic study of mitochondrial complex I and glutamate receptors in the basal ganglia of rats after unilateral subthalamic lesion.

Neuroscience letters, 1995, Feb-17, Volume: 186, Issue:2-3

A unilateral lesion of the subthalamic nucleus (STN) induced, in the short-term (< or = 1 week), an ipsilateral decrease in [3H]dihydrorotenone binding to complex I in entopeduncular nucleus and substantia nigra pars reticulata (SNr). A slight reduction of [3H]MK-801 binding to N-methyl-D-aspartate (NMDA) receptors in the ipsilateral SNr was also found, whereas no changes in [3H]alpha-amino-3-hydroxy-5-methylisoxazole propionic acid binding were observed. The complex I decrease likely reflects a reduction in neuronal activity subsequent to the interruption of excitatory signaling from STN. The unexpected decrease in [3H]MK-801 binding in SNr may be related to presynaptic NMDA receptor modifications.

Topics: Animals; Autoradiography; Basal Ganglia; Dizocilpine Maleate; Histocytochemistry; Male; Mitochondria; NAD(P)H Dehydrogenase (Quinone); Rats; Rats, Sprague-Dawley; Receptors, AMPA; Receptors, Glutamate; Rotenone; Thalamic Nuclei

1995