Page last updated: 2024-09-02

dityrosine and mocetinostat

dityrosine has been researched along with mocetinostat in 37 studies

Compound Research Comparison

Studies
(dityrosine)
Trials
(dityrosine)
Recent Studies (post-2010)
(dityrosine)
Studies
(mocetinostat)
Trials
(mocetinostat)
Recent Studies (post-2010) (mocetinostat)
376611621,7353908,606

Protein Interaction Comparison

ProteinTaxonomydityrosine (IC50)mocetinostat (IC50)
Histone deacetylase 3Homo sapiens (human)0.7851
Nuclear receptor corepressor 1Homo sapiens (human)0.022
Cytochrome P450 3A4Homo sapiens (human)0.57
Cytochrome P450 2D6Homo sapiens (human)0.102
Cytochrome P450 2C19Homo sapiens (human)0.102
Histone deacetylase 4Homo sapiens (human)0.5717
Histone deacetylase 1Homo sapiens (human)0.3433
Histone deacetylase 7Homo sapiens (human)0.6725
Histone deacetylase 2Homo sapiens (human)0.3537
Histone deacetylase 11 Homo sapiens (human)0.6386
Histone deacetylase 8Homo sapiens (human)0.6725
Histone deacetylase 6Homo sapiens (human)0.5717
Histone deacetylase 5Homo sapiens (human)0.6725
Nuclear receptor corepressor 2Homo sapiens (human)0.045

Research

Studies (37)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's18 (48.65)18.2507
2000's10 (27.03)29.6817
2010's8 (21.62)24.3611
2020's1 (2.70)2.80

Authors

AuthorsStudies
Blarzino, C; Coccia, R; De Marco, C; Foppoli, C; Rosei, MA1
Vissers, MC; Winterbourn, CC1
Beer, K; Goodenough, UW; Waffenschmidt, S; Woessner, JP1
Daehnke, HL; Goldstein, JA; Heinecke, JW; Li, W1
Francis, GA; Goldstein, JA; Heinecke, JW; Li, W1
Inaba, H; Nakano, M; Totsune, H1
Dunford, HB; Marquez, LA1
Hazen, SL; Heinecke, JW; Hsu, FF1
Cistola, DP; Hazen, SL; Heinecke, JW; Hsu, FF; Jacob, JS; Mueller, DM; Muzaffar, S1
Christensen, BM; Hodgeman, BA; Li, J1
Nakano, M; Nishida, A; Totsune, H; Ushijima, Y1
Heinecke, JW; Hsu, FF; Leeuwenburgh, C; Mueller, DM; Pennathur, S; Rasmussen, JE1
Kettle, AJ; Pichorner, H; Winterbourn, CC1
Baudry, N; Carayon, P; Delom, F; Lejeune, PJ; Mallet, B; Vinet, L1
Stanbro, WD1
Britigan, BE; Buettner, GR; Gaut, JP; Heinecke, JW; Lin, TS; McCormick, ML1
Franceschi, C; Galeazzi, L; Giunta, S; Ronchi, P1
Tien, M1
Han, Q; Li, G; Li, J1
Cross, CE; Eiserich, JP; Marelich, GP; Nguyen, MN; Shigenaga, MK; Van Der Vliet, A1
Brivio, MF; de Eguileor, M; Grimaldi, A; Lanzavecchia, G; Valvassori, R; Vigetti, D1
Heinecke, JW1
Kato, Y; Nagao, A; Osawa, T; Terao, J1
Herold, S1
Chung, HY; Lee, J; Son, TG; Yu, BP; Zou, Y1
Homma, S; Kato, Y; Kawakishi, S; Murata, M; Takasaki, S1
Chuman, H; Ishisaka, A; Kato, Y; Kawabata, K; Kawai, Y; Kinoshita, T; Naito, M; Shiba, Y; Takeda, E; Taketani, Y; Terao, J1
Adamchuk, RI; Oparin, AY; Stepuro, AI; Stepuro, II1
Barillas-Mury, C; Gupta, L; Kumar, S; Molina-Cruz, A; Rodrigues, J1
Ageeva, TS; Bezmenova, MA; Ivanov, VV; Petina, GV; Riazantseva, NV; Stepovaia, EA; Tetenev, FF; Zhavoronok, TV1
de Koning, LJ; de Koster, CG; Dekker, HL; Gruppen, H; Heijnis, WH; van Berkel, WJ; Westphal, AH; Wierenga, PA1
Belli, SI; Davies, MJ; Feng, ZP; Katrib, M; Luxford, C; Mai, K; Norton, RS; Slapeta, J; Slapetova, I; Smith, NC; Wallach, MG; Zhang, X1
Bolton, S; Cadogan, EB; Churg, A; Mallinder, PR; Maltby, J; Marshall, CV; Sin, DD; Soars, MG; Thain, K; Wright, JL; Zhou, S1
Pal, U; Smith, AA; Williams, MS; Yang, X1
Bender, F; Biancini, GB; Burin, MG; Coitinho, AS; da Rosa, HT; Deon, M; Donida, B; Giugliani, R; Manini, PR; Marchetti, DP; Moura, DJ; Saffi, J; Vargas, CR1
Gao, Z; Li, H; Xu, H; Yang, Z1
Bernard, K; Bone, NB; Byun, J; Johnson, MR; Kurundkar, A; Locy, ML; Pennathur, S; Rangarajan, S; Thannickal, VJ; Yang, S; Zhou, Y; Zmijewski, JW1

Reviews

1 review(s) available for dityrosine and mocetinostat

ArticleYear
Tyrosyl radical production by myeloperoxidase: a phagocyte pathway for lipid peroxidation and dityrosine cross-linking of proteins.
    Toxicology, 2002, Aug-01, Volume: 177, Issue:1

    Topics: Arteriosclerosis; Cross-Linking Reagents; Free Radicals; Humans; Lipid Peroxidation; Oxidation-Reduction; Peroxidase; Phagocytes; Proteins; Tyrosine

2002

Other Studies

36 other study(ies) available for dityrosine and mocetinostat

ArticleYear
The peroxidase-catalyzed oxidation of enkephalins.
    Biochemical and biophysical research communications, 1991, Aug-30, Volume: 179, Issue:1

    Topics: Chromatography, High Pressure Liquid; Chromatography, Ion Exchange; Enkephalin, Leucine; Enkephalin, Methionine; Horseradish Peroxidase; Kinetics; Lactoperoxidase; Oxidation-Reduction; Peroxidase; Peroxidases; Spectrophotometry, Ultraviolet; Tyrosine

1991
Oxidative damage to fibronectin. I. The effects of the neutrophil myeloperoxidase system and HOCl.
    Archives of biochemistry and biophysics, 1991, Feb-15, Volume: 285, Issue:1

    Topics: Azides; Chloramines; Fibronectins; Fluorescence; Humans; Hydrogen Peroxide; Hypochlorous Acid; Methionine; Molecular Weight; Neutrophils; Pancreatic Elastase; Peroxidase; Protein Denaturation; Tryptophan; Tyrosine

1991
Isodityrosine cross-linking mediates insolubilization of cell walls in Chlamydomonas.
    The Plant cell, 1993, Volume: 5, Issue:7

    Topics: Amino Acid Sequence; Animals; Ascorbic Acid; Base Sequence; Cell Wall; Chlamydomonas reinhardtii; Cloning, Molecular; Cross-Linking Reagents; Epitopes; Glycoproteins; Hydrogen Peroxide; Molecular Sequence Data; Peroxidase; RNA, Messenger; Solubility; Tyrosine

1993
Dityrosine, a specific marker of oxidation, is synthesized by the myeloperoxidase-hydrogen peroxide system of human neutrophils and macrophages.
    The Journal of biological chemistry, 1993, Feb-25, Volume: 268, Issue:6

    Topics: Cells, Cultured; Chromatography, Liquid; Free Radicals; Humans; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Macrophages; Mass Spectrometry; Neutrophils; Oxidation-Reduction; Peroxidase; Spectrum Analysis; Tyrosine

1993
Tyrosyl radical generated by myeloperoxidase catalyzes the oxidative cross-linking of proteins.
    The Journal of clinical investigation, 1993, Volume: 91, Issue:6

    Topics: Amino Acid Sequence; Cross-Linking Reagents; Dipeptides; Free Radicals; Humans; Molecular Sequence Data; Neutrophils; Oligopeptides; Oxidation-Reduction; Peroxidase; Serum Albumin, Bovine; Tyrosine

1993
Chemiluminescence from bamboo shoot cut.
    Biochemical and biophysical research communications, 1993, Aug-16, Volume: 194, Issue:3

    Topics: Image Processing, Computer-Assisted; Luminescent Measurements; Peroxidase; Poaceae; Tyrosine

1993
Kinetics of oxidation of tyrosine and dityrosine by myeloperoxidase compounds I and II. Implications for lipoprotein peroxidation studies.
    The Journal of biological chemistry, 1995, Dec-22, Volume: 270, Issue:51

    Topics: Animals; Catalysis; Cattle; Hydrogen Peroxide; Hydrogen-Ion Concentration; Kinetics; Lipid Peroxidation; Lipoproteins; Peroxidase; Spectrometry, Fluorescence; Spectrophotometry; Spleen; Tyrosine

1995
p-Hydroxyphenylacetaldehyde is the major product of L-tyrosine oxidation by activated human phagocytes. A chloride-dependent mechanism for the conversion of free amino acids into reactive aldehydes by myeloperoxidase.
    The Journal of biological chemistry, 1996, Jan-26, Volume: 271, Issue:4

    Topics: Acetaldehyde; Cells, Cultured; Chlorides; Chromatography, High Pressure Liquid; Fourier Analysis; Humans; Magnetic Resonance Spectroscopy; Neutrophils; Oxidation-Reduction; Peroxidase; Phagocytes; Phenol; Superoxides; Tyrosine

1996
Human phagocytes employ the myeloperoxidase-hydrogen peroxide system to synthesize dityrosine, trityrosine, pulcherosine, and isodityrosine by a tyrosyl radical-dependent pathway.
    The Journal of biological chemistry, 1996, Aug-16, Volume: 271, Issue:33

    Topics: Free Radicals; Humans; Hydrogen Peroxide; Neutrophils; Oxidation-Reduction; Peroxidase; Proteins; Spectrometry, Fluorescence; Spectrophotometry, Ultraviolet; Tyrosine

1996
Involvement of peroxidase in chorion hardening in Aedes aegypti.
    Insect biochemistry and molecular biology, 1996, Volume: 26, Issue:3

    Topics: Aedes; Animals; Chorion; Egg Proteins; Female; Hydrogen Peroxide; Ovum; Peroxidase; Time Factors; Tyrosine

1996
Chemiluminescence from human polymorphonuclear leukocytes activated with opsonized zymosan.
    Free radical biology & medicine, 1997, Volume: 22, Issue:3

    Topics: Humans; Hydrogen Peroxide; Luminescent Measurements; Neutrophils; Opsonin Proteins; Peroxidase; Tyrosine; Zymosan

1997
Mass spectrometric quantification of markers for protein oxidation by tyrosyl radical, copper, and hydroxyl radical in low density lipoprotein isolated from human atherosclerotic plaques.
    The Journal of biological chemistry, 1997, Feb-07, Volume: 272, Issue:6

    Topics: Animals; Aorta; Arteriosclerosis; Cattle; Copper; Endothelium, Vascular; Gas Chromatography-Mass Spectrometry; Humans; Hydroxyl Radical; Lipoproteins, LDL; Mass Spectrometry; Oxidation-Reduction; Peroxidase; Phenylalanine; Tyrosine

1997
Myeloperoxidase-dependent generation of a tyrosine peroxide by neutrophils.
    Archives of biochemistry and biophysics, 1997, Feb-01, Volume: 338, Issue:1

    Topics: Chromatography, High Pressure Liquid; Humans; Hydrogen Peroxide; In Vitro Techniques; Kinetics; Neutrophils; Oxidation-Reduction; Peroxidase; Peroxides; Superoxides; Tetradecanoylphorbol Acetate; Tyrosine

1997
Role of multimerized porcine thyroglobulin in iodine storage.
    Biochemical and biophysical research communications, 1998, Jan-14, Volume: 242, Issue:2

    Topics: Amino Acids; Animals; Diiodotyrosine; Disulfides; Electrophoresis, Polyacrylamide Gel; Hydrogen Peroxide; Iodides; Iodine; Microscopy, Electron, Scanning; Monoiodotyrosine; Peroxidase; Pronase; Protein Conformation; Swine; Thyroglobulin; Thyroid Gland; Thyroxine; Triiodothyronine; Trypsin; Tyrosine

1998
A kinetic model of the myeloperoxidase-hydrogen peroxide-chloride ion system in phagolysosomes.
    Journal of theoretical biology, 1998, Jul-07, Volume: 193, Issue:1

    Topics: Animals; Chlorides; Hydrogen Peroxide; Mammals; Models, Biological; Neutrophils; Oxidative Stress; Peroxidase; Peroxides; Phagosomes; Taurine; Tyrosine

1998
Electron paramagnetic resonance detection of free tyrosyl radical generated by myeloperoxidase, lactoperoxidase, and horseradish peroxidase.
    The Journal of biological chemistry, 1998, Nov-27, Volume: 273, Issue:48

    Topics: Animals; Arteriosclerosis; Cattle; Electron Spin Resonance Spectroscopy; Free Radicals; Horseradish Peroxidase; Humans; Hydrogen Peroxide; Inflammation; Kinetics; Lactoperoxidase; Lipid Peroxidation; Oxidation-Reduction; Peroxidase; Pronase; Tyrosine

1998
In vitro peroxidase oxidation induces stable dimers of beta-amyloid (1-42) through dityrosine bridge formation.
    Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis, 1999, Volume: 6, Issue:1

    Topics: Amino Acid Sequence; Amyloid beta-Peptides; Chromatography, High Pressure Liquid; Dimerization; Electrophoresis, Polyacrylamide Gel; Hydrolysis; Molecular Sequence Data; Oxidation-Reduction; Peptide Fragments; Peroxidase; Spectrometry, Fluorescence; Tyrosine

1999
Myeloperoxidase-catalyzed oxidation of tyrosine.
    Archives of biochemistry and biophysics, 1999, Jul-01, Volume: 367, Issue:1

    Topics: Animals; Cattle; Cross-Linking Reagents; Cysteine; Free Radicals; Glutathione; Kinetics; Methionine; Molecular Weight; Oxidants; Oxidation-Reduction; Peptides; Peroxidase; Sulfhydryl Reagents; Tyrosine

1999
Purification and characterization of chorion peroxidase from Aedes aegypti eggs.
    Archives of biochemistry and biophysics, 2000, Jun-01, Volume: 378, Issue:1

    Topics: Aedes; Amino Acid Sequence; Amino Acids; Animals; Chorion; Cross-Linking Reagents; Female; Horseradish Peroxidase; Molecular Weight; Ovum; Oxidation-Reduction; Peroxidase; Protein Denaturation; Sodium Dodecyl Sulfate; Solubility; Spectrophotometry; Substrate Specificity; Tyrosine

2000
Myeloperoxidase and protein oxidation in cystic fibrosis.
    American journal of physiology. Lung cellular and molecular physiology, 2000, Volume: 279, Issue:3

    Topics: Adult; Bronchi; Case-Control Studies; Cell Line; Chromatography, High Pressure Liquid; Cystic Fibrosis; Drug Synergism; Humans; Hydrogen Peroxide; Nitrates; Nitrites; Oxidants; Oxidation-Reduction; Peroxidase; Peroxidases; Proteins; Respiratory System; Sputum; Trachea; Tyrosine

2000
Structural and biochemical analysis of the parasite Gordius villoti (Nematomorpha, Gordiacea) cuticle.
    Tissue & cell, 2000, Volume: 32, Issue:5

    Topics: Animals; Chromatography, High Pressure Liquid; Chromatography, Thin Layer; Collagenases; Electrophoresis, Polyacrylamide Gel; Epithelium; Helminths; Image Processing, Computer-Assisted; Microscopy, Electron; Microscopy, Video; Peroxidase; Spectrophotometry; Tyrosine; Ultraviolet Rays

2000
Inhibition of myeloperoxidase-catalyzed tyrosylation by phenolic antioxidants in vitro.
    Bioscience, biotechnology, and biochemistry, 2003, Volume: 67, Issue:5

    Topics: Antioxidants; Buffers; Chromatography, High Pressure Liquid; Coumaric Acids; Curcumin; Enzyme Inhibitors; Gallic Acid; Peroxidase; Phenols; Quercetin; Spectrometry, Fluorescence; Tyrosine

2003
Nitrotyrosine, dityrosine, and nitrotryptophan formation from metmyoglobin, hydrogen peroxide, and nitrite.
    Free radical biology & medicine, 2004, Mar-01, Volume: 36, Issue:5

    Topics: Hydrogen Peroxide; Methemoglobin; Metmyoglobin; Myoglobin; Nitrites; Peroxidase; Peroxynitrous Acid; Tryptophan; Tyrosine

2004
Aging effect on myeloperoxidase in rat kidney and its modulation by calorie restriction.
    Free radical research, 2005, Volume: 39, Issue:3

    Topics: Aging; Animals; Caloric Restriction; Diet; Energy Intake; Inflammation; Kidney; Lipopolysaccharides; Male; Oxidation-Reduction; Oxidative Stress; Peroxidase; Rats; Rats, Inbred F344; Tyrosine; Vascular Cell Adhesion Molecule-1

2005
Effects of peroxidase and hydrogen peroxide on the dityrosine formation and the mixing characteristics of wheat-flour dough.
    Bioscience, biotechnology, and biochemistry, 2005, Volume: 69, Issue:9

    Topics: Bread; Chromatography, High Pressure Liquid; Chromatography, Liquid; Cross-Linking Reagents; Flour; Hydrogen Peroxide; Mass Spectrometry; Peroxidase; Tyrosine

2005
Flavonoids as substrates and inhibitors of myeloperoxidase: molecular actions of aglycone and metabolites.
    Chemical research in toxicology, 2008, Volume: 21, Issue:8

    Topics: Administration, Oral; Animals; Antioxidants; Aorta; Atherosclerosis; Computer Simulation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Free Radical Scavengers; HL-60 Cells; Humans; Macrophages; Peroxidase; Quantitative Structure-Activity Relationship; Quercetin; Rats; Rats, Inbred Strains; Tyrosine

2008
Thiamine inhibits formation of dityrosine, a specific marker of oxidative injury, in reactions catalyzed by oxoferryl forms of hemoglobin.
    Biochemistry. Biokhimiia, 2008, Volume: 73, Issue:9

    Topics: Hemoglobins; Humans; Kinetics; Metmyoglobin; Oxidation-Reduction; Peroxidase; Thiamine; Tyrosine

2008
A peroxidase/dual oxidase system modulates midgut epithelial immunity in Anopheles gambiae.
    Science (New York, N.Y.), 2010, Mar-26, Volume: 327, Issue:5973

    Topics: Animals; Anopheles; Anti-Bacterial Agents; Bacteria; Bacterial Physiological Phenomena; Blood; Digestive System; Enzyme Induction; Epithelial Cells; Extracellular Matrix; Female; Gene Expression Regulation; Insect Proteins; Models, Biological; NADPH Oxidases; Nitric Oxide Synthase; Permeability; Peroxidase; Plasmodium berghei; Plasmodium falciparum; RNA Interference; Tyrosine

2010
[The functional properties and oxidative modification of plasma and neutrophil proteins in community-acquired pneumonia].
    Klinicheskaia laboratornaia diagnostika, 2010, Issue:3

    Topics: Adolescent; Adult; Community-Acquired Infections; Female; Humans; Hydroxyl Radical; Lung; Male; Middle Aged; Neutrophils; Oxidation-Reduction; Oxidative Stress; Peroxidase; Plasma; Pneumonia; Protein Carbonylation; Tryptophan; Tyrosine; Young Adult

2010
Identification of the peroxidase-generated intermolecular dityrosine cross-link in bovine α-lactalbumin.
    Journal of agricultural and food chemistry, 2011, Jan-12, Volume: 59, Issue:1

    Topics: Animals; Cattle; Cross-Linking Reagents; Lactalbumin; Oxidation-Reduction; Peroxidase; Protein Conformation; Tyrosine

2011
Peroxidase catalysed cross-linking of an intrinsically unstructured protein via dityrosine bonds in the oocyst wall of the apicomplexan parasite, Eimeria maxima.
    International journal for parasitology, 2011, Volume: 41, Issue:11

    Topics: Biocatalysis; Cell Wall; Cross-Linking Reagents; Eimeria; Oocysts; Peroxidase; Protein Structure, Tertiary; Protozoan Proteins; Tyrosine

2011
Late intervention with a myeloperoxidase inhibitor stops progression of experimental chronic obstructive pulmonary disease.
    American journal of respiratory and critical care medicine, 2012, Jan-01, Volume: 185, Issue:1

    Topics: Airway Remodeling; Animals; Dinoprost; Disease Models, Animal; Disease Progression; Enzyme Inhibitors; Female; Guinea Pigs; Hypertension, Pulmonary; Inflammation; Lung; Oxidative Stress; Peroxidase; Pulmonary Disease, Chronic Obstructive; Purines; Smoking; Thiones; Thioxanthenes; Tyrosine

2012
A dityrosine network mediated by dual oxidase and peroxidase influences the persistence of Lyme disease pathogens within the vector.
    The Journal of biological chemistry, 2014, May-02, Volume: 289, Issue:18

    Topics: Animals; Arthropod Proteins; Arthropod Vectors; Borrelia burgdorferi; Gastrointestinal Tract; Gene Expression Regulation, Enzymologic; Humans; Ixodes; Lyme Disease; Mice; Mice, Inbred C3H; Microbial Viability; Microscopy, Confocal; NADPH Oxidases; Peroxidase; Reverse Transcriptase Polymerase Chain Reaction; RNA Interference; Signal Transduction; Tyrosine

2014
Oxidative stress and inflammation in mucopolysaccharidosis type IVA patients treated with enzyme replacement therapy.
    Biochimica et biophysica acta, 2015, Volume: 1852, Issue:5

    Topics: 8-Hydroxy-2'-Deoxyguanosine; Adolescent; Adult; Blood Proteins; Child; Chondroitinsulfatases; Creatinine; Cytokines; Deoxyguanosine; Enzyme Replacement Therapy; Erythrocytes; Female; Glutathione; Glycosaminoglycans; Humans; Inflammation; Isoprostanes; Male; Mucopolysaccharidosis IV; Oxidative Stress; Peroxidase; Superoxide Dismutase; Treatment Outcome; Tyrosine; Young Adult

2015
Hemin-Graphene Derivatives with Increased Peroxidase Activities Restrain Protein Tyrosine Nitration.
    Chemistry (Weinheim an der Bergstrasse, Germany), 2017, Dec-14, Volume: 23, Issue:70

    Topics: Animals; Biocompatible Materials; Catalysis; Cattle; Chromatography, High Pressure Liquid; Free Radicals; Graphite; Hemin; Hydrogen Peroxide; Microscopy, Atomic Force; Nitrates; Nitrites; Oxidation-Reduction; Peroxidase; Serum Albumin, Bovine; Spectroscopy, Fourier Transform Infrared; Tyrosine

2017
Oxidative cross-linking of fibronectin confers protease resistance and inhibits cellular migration.
    Science signaling, 2020, 08-11, Volume: 13, Issue:644

    Topics: A549 Cells; Animals; Cell Line; Cell Movement; Cells, Cultured; Cross-Linking Reagents; Extracellular Matrix; Female; Fibronectins; Humans; Mice, Inbred C57BL; Mice, Knockout; Myofibroblasts; Neutrophils; Oxidation-Reduction; Oxidative Stress; Peptide Hydrolases; Peroxidase; Transforming Growth Factor beta1; Tyrosine

2020