Page last updated: 2024-08-20

ditiocarb and acetaminophen

ditiocarb has been researched along with acetaminophen in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19905 (33.33)18.7374
1990's6 (40.00)18.2507
2000's3 (20.00)29.6817
2010's1 (6.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Harvey, FD; Levitt, TE1
Siegers, CP1
Lauriault, VV; O'Brien, PJ1
Möller-Hartmann, W; Siegers, CP1
Plewa, MJ; Verdier, MM; Wagner, ED1
Lemoine, R; Sause, C; Siegers, CP; Younes, M1
Siegers, CP; Younes, M1
Fischer, LJ; Harman, AW1
Plewa, MJ1
Kunze, KL; Lee, CA; Nelson, SD; Slattery, JT; Thummel, KE1
Alexander, A; Berthou, F; Mapoles, J; Ménez, JF; Simon, F1
Hazai, E; Monostory, K; Vereczkey, L1

Reviews

1 review(s) available for ditiocarb and acetaminophen

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000

Other Studies

14 other study(ies) available for ditiocarb and acetaminophen

ArticleYear
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Experimental evaluation of paracetamol antidotes.
    The Journal of international medical research, 1976, Volume: 4, Issue:4 Suppl

    Topics: Acetaminophen; Animals; Antidotes; Bile; Cysteamine; Cysteine; Ditiocarb; Glutathione; Imidazoles; In Vitro Techniques; Liver; Methionine; Mice; Rats

1976
Influence of dithiocarb on the biliary excretion of paracetamol and bilirubin in rats.
    Experientia, 1978, Oct-15, Volume: 34, Issue:10

    Topics: Acetaminophen; Animals; Bile; Bilirubin; Ditiocarb; Glucuronates; Male; Rats; Thiocarbamates

1978
Molecular mechanism for prevention of N-acetyl-p-benzoquinoneimine cytotoxicity by the permeable thiol drugs diethyldithiocarbamate and dithiothreitol.
    Molecular pharmacology, 1991, Volume: 40, Issue:1

    Topics: Acetaminophen; Alkylation; Animals; Benzoquinones; Cell Survival; Dithiothreitol; Ditiocarb; Glutathione; Imines; Liver; Male; Oxidation-Reduction; Rats; Rats, Inbred Strains

1991
Nephrotoxicity of paracetamol in the rat--mechanistic and therapeutic aspects.
    Journal of applied toxicology : JAT, 1991, Volume: 11, Issue:2

    Topics: Acetaminophen; Acetylcysteine; Acetylglucosaminidase; Animals; Antidotes; Ditiocarb; gamma-Glutamyltransferase; Kidney Diseases; L-Iditol 2-Dehydrogenase; Male; Rats; Rats, Inbred Strains

1991
The biochemical mechanisms of the plant activation of promutagenic aromatic amines.
    Environmental and molecular mutagenesis, 1990, Volume: 15, Issue:4

    Topics: Acetaminophen; Benzoflavones; Biotransformation; Catechin; Cell Line; Ditiocarb; Fluorenes; Methimazole; Metyrapone; Mutagens; Mutation; Nicotiana; Oxidoreductases; Oxygenases; Phenylenediamines; Plants, Toxic; Potassium Cyanide

1990
Effect of deferrioxamine and diethyldithiocarbamate on paracetamol-induced hepato- and nephrotoxicity. The role of lipid peroxidation.
    Journal of applied toxicology : JAT, 1988, Volume: 8, Issue:4

    Topics: Acetaminophen; Animals; Creatinine; Deferoxamine; Ditiocarb; Ethane; Glutathione; Kidney; Lipid Peroxides; Liver; Male; Malondialdehyde; Mice

1988
Inhibition of the hepatotoxicity of paracetamol and its irreversible binding to rat liver microsomal protein.
    Archives of toxicology, 1980, Volume: 45, Issue:1

    Topics: Acetaminophen; Animals; Catechin; Chemical and Drug Induced Liver Injury; Deanol; Dimethyl Sulfoxide; Ditiocarb; In Vitro Techniques; Microsomes, Liver; Phenobarbital; Protein Binding; Rats; Time Factors

1980
Hamster hepatocytes in culture as a model for acetaminophen toxicity studies with inhibitors of drug metabolism.
    Toxicology and applied pharmacology, 1983, Volume: 71, Issue:3

    Topics: Acetaminophen; Animals; Cells, Cultured; Cricetinae; Cytochrome P-450 Enzyme System; Ditiocarb; Dose-Response Relationship, Drug; Glutathione; L-Lactate Dehydrogenase; Liver; Male; Malondialdehyde; Mesocricetus; Metyrapone; Oxidation-Reduction; Piperonyl Butoxide

1983
Blocking the plant activation of promutagenic aromatic amines by peroxidase inhibitors.
    Basic life sciences, 1993, Volume: 61

    Topics: Acetaminophen; Antimutagenic Agents; Benzoflavones; Catechin; Cells, Cultured; Ditiocarb; Methimazole; Metyrapone; Mutagenicity Tests; Mutagens; Peroxidases; Plants; Potassium Cyanide; Prodrugs; Salmonella typhimurium

1993
Oxidation of acetaminophen to N-acetyl-p-aminobenzoquinone imine by human CYP3A4.
    Biochemical pharmacology, 1993, Apr-22, Volume: 45, Issue:8

    Topics: Acetaminophen; Benzoquinones; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Ditiocarb; Dose-Response Relationship, Drug; Humans; Imines; Intestines; Isoenzymes; Kinetics; Liver; Microsomes, Liver; Mixed Function Oxygenases

1993
Mammalian PC-12 cell genetically engineered for human cytochrome P450 2E1 expression.
    European journal of biochemistry, 1993, Jun-15, Volume: 214, Issue:3

    Topics: 1-Butanol; Acetaminophen; Animals; Butanols; Chlorzoxazone; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dimethylnitrosamine; Ditiocarb; Genetic Engineering; Humans; Hydroxylation; Microsomes; Oxidoreductases, N-Demethylating; Oxygenases; PC12 Cells; Transfection

1993
Reduction of toxic metabolite formation of acetaminophen.
    Biochemical and biophysical research communications, 2002, Mar-08, Volume: 291, Issue:4

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Benzoquinones; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Disulfiram; Ditiocarb; Enzyme Inhibitors; Fomepizole; Humans; Imines; Microsomes, Liver; Pyrazoles

2002