dithizone has been researched along with dihydroxyethyldithiocarbamate* in 2 studies
2 other study(ies) available for dithizone and dihydroxyethyldithiocarbamate
| Article | Year |
|---|---|
Diethyldithiocarbamate and dithizone augment the toxicity of kainic acid.
Male Fischer-344 rats were injected i.p. with diethyldithiocarbamate or dithizone 15 min after kainic acid (KA), s.c. Diethyldithiocarbamate and dithizone reduced both the number of wet dog shakes and the latency to onset of seizures induced by KA. Moreover, they increased the severity of seizures. These compounds may be useful tools for investigating the role of zinc in central nervous system excitatory transmission and/or convulsive phenomena. Topics: Animals; Azo Compounds; Chelating Agents; Dithizone; Ditiocarb; Kainic Acid; Male; Rats; Rats, Inbred F344; Reaction Time; Seizures; Zinc | 1990 |
[Effects of chelating reagents on the hippocampal EEG and histochemical Timm staining pattern in a mouse brain].
A series of experiments we examined in detail the effects of four chelating reagents, dithizone, DEDTC, oxine and EDTA, upon (1) Timm's staining in the hippocampal formation, (2) brain electrical activity recorded from hippocampal and cortical electrodes, (3) recovery effect with zinc acetate or zinc sulfate on abolished brain electrical activity, (4) open field activity, (5) toxicity, (6) and heart rate. Dithizone, DEDTC and oxine influenced all measures, and the degree of effect varied directory with dose. But EDTA has not any significant effect on biological system. Resulting data were summarized in Table 4. Topics: Animals; Brain; Chelating Agents; Dithizone; Ditiocarb; Electroencephalography; Female; Hippocampus; Male; Mice; Staining and Labeling | 1987 |