dithiothreitol has been researched along with thyroxine in 96 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 70 (72.92) | 18.7374 |
1990's | 17 (17.71) | 18.2507 |
2000's | 4 (4.17) | 29.6817 |
2010's | 4 (4.17) | 24.3611 |
2020's | 1 (1.04) | 2.80 |
Authors | Studies |
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Docter, R; Does-Tobé, I; Hennemann, G; Visser, TJ | 1 |
Docter, R; Fekkes, D; Hennemann, G; Visser, TJ | 1 |
Gharbi, J; Torresani, J | 1 |
DeGroot, LJ; Torresani, J | 1 |
Braverman, LE; Fang, SL; Harris, AR; Hinerfeld, L; Vagenakis, AG | 1 |
Kaplan, MM | 2 |
Hershman, JM; Kurtzman, G; Melmed, S; Reed, A | 1 |
Breitbart, R; Kaplan, MM; Larsen, PR; Tatro, JB | 1 |
Chopra, IJ | 2 |
Woeber, KA | 1 |
Cheron, RG; Dick, TE; Kaplan, MM; Larsen, PR; Silva, JE | 1 |
Leonard, JL; Rosenberg, IN | 3 |
Byamungu, N; Kühn, ER; Mol, K | 1 |
Eales, JG; MacLatchy, DL | 1 |
Asano, Y; Kusano, E; Murayama, N; Sakurada, T; Yamaki, M; Yoshida, K | 1 |
Badinga, L; Bazer, FW; Collier, RJ; Head, HH; Thatcher, WW; Wilcox, CJ | 1 |
Florsheim, W; Parker, LN; Wright, C; Wu, SY | 1 |
Goswami, A; Rosenberg, IN | 3 |
Jacobs, GF; Kühn, ER | 1 |
Borges, M; Ingbar, SH; Silva, JE | 1 |
Brzezińska-Slebodzińska, E; Kapluk, J | 1 |
Bitman, J; Kahl, S; Rumsey, TS | 1 |
Boado, RJ; Chopra, IJ | 1 |
Banovac, K; Rabinovitch, A; Zakarija, M | 1 |
Croteau, W; St Germain, DL | 1 |
Boado, RJ; Chopra, IJ; Huang, TS; Solomon, DH; Teco, GN | 1 |
Jacobs, GF; Kühn, ER; Vandorpe, G | 1 |
Galton, VA; Hiebert, A | 1 |
St Germain, DL | 2 |
Flett, PA; Leatherland, JF; Vijayan, MM | 1 |
Rudas, P | 1 |
Saito, H; Saito, S; Sakurada, T; Sugihira, N; Suzuki, M; Yoshida, K; Yoshinaga, K | 1 |
Larsen, PR; Mellen, S; Silva, JE | 1 |
Barlow, JW; Csicsmann, JM; Lim, CF; Meinhold, H; Stockigt, JR | 1 |
Hardy, JJ; Thomas, CL; Utiger, RD | 1 |
Harvey, S; Lam, SK | 1 |
Amir, SM; Braverman, LE; Ingbar, SH; Ruiz, M; Yabu, Y | 1 |
Fisher, DA; Polk, DH; Wu, SY | 1 |
Beredo, A; Chopra, IJ; Huang, TS; Solomon, DH | 2 |
Fisher, DA; Klein, AH; Polk, DH; Wu, SY | 1 |
Larsen, PR; Leonard, JL | 1 |
Mol, JA; Visser, TJ | 1 |
Courtin, F; Pelletier, G; Walker, P | 1 |
Finkelstein, JD; Harris, B | 1 |
Goswami, A; Leonard, JL; Rosenberg, IN | 1 |
Chazenbalk, GD; Juvenal, GJ; Kleiman de Pisarev, DL; Pisarev, MA | 1 |
Utiger, RD | 1 |
Kajiwara, S; Kato, T; Kita, K; Miyamori, C; Sato, T | 1 |
Brzezińska-Slebodzińska, E; Drews, R; Slebodziński, AB | 1 |
Horike, S; Kamikubo, K; Nakamura, S; Sakata, S; Yasuda, K | 1 |
Fukazawa, H; Kaise, K; Kaise, N; Kitaoka, H; Saito, S; Sakurada, T; Suzuki, M; Yamamoto, M; Yoshida, K; Yoshinaga, K | 1 |
Fukazawa, H; Kaise, K; Kaise, N; Kitaoka, H; Saito, S; Sakurada, T; Yamamoto, M; Yoshida, K; Yoshinaga, K | 1 |
Braverman, LE; Emerson, CH; Fang, SL; Green, K; Roti, E | 2 |
Di Giorgio, RM; Ientile, R; Macaione, S; Pugliese, G; Russo, P | 1 |
Robbins, J; Sato, K | 1 |
Barlow, JW; Csicsmann, JM; Funder, JW; Stockigt, JR; White, EL | 1 |
Kaplan, MM; Larsen, PR; Leonard, JL; Visser, TJ | 1 |
Kaplan, MM; Leonard, JL; Visser, TJ; Yaskoski, KA | 1 |
Braverman, LE; Emerson, CH; Fay, M; Shulkin, BL; Utiger, RD | 1 |
Imura, H; Inada, M; Ishii, H; Mashio, Y; Naito, K; Nishikawa, M; Tanaka, K | 2 |
Ozawa, Y; Shimizu, T; Shishiba, Y | 1 |
Boye, N; Laurberg, P | 1 |
Balsam, A; Ingbar, SH; Segall-Blank, M | 1 |
Braverman, LE; Emerson, CH; Fang, SL; Roti, E | 1 |
Cheron, RG; Kaplan, MM; Larsen, PR | 1 |
Kaplan, MM; Yaskoski, KA | 1 |
Imai, Y; Kataoka, K; Nishikimi, M | 1 |
Imai, Y | 1 |
Borges, M; Ingbar, SH; LaBourene, J | 1 |
Itokawa, Y; Kimura, M; Zhu, Z | 1 |
Gonzalez Pondal, M; Hagmüller, K; Noli, MI; Paier, B; Stiegler, C; Zaninovich, AA | 1 |
de Luze, A; DiStefano, JJ; Nguyen, TT | 1 |
Montiel, M; Morata, P; Morell, M; Serrano-Lozano, A | 1 |
Eales, JG; Frith, SD | 1 |
Darras, VM; Kühn, ER; Mol, KA; Van Der Geyten, S; Visser, TJ | 1 |
Duchamp, C; Gabarrou, JF; Géraert, PA; Williams, J | 1 |
Brett, SE; Leary, SC; Leatherland, JF; Welsh, DG | 1 |
Eales, JG; McLeese, JM; Wright, GM; Youson, JH | 1 |
Chen, M; Ding, L; Lian, G; Liu, L; Ni, J; Zhao, D | 1 |
Darras, VM; Evans, BK; Kühn, ER; Richardson, SJ; Shepherdley, CA | 1 |
Klootwijk, W; Kuiper, GG; Visser, TJ | 1 |
Gereben, B; Goemann, IM; Harney, JW; Larsen, PR; Maia, AL; Zhu, B | 1 |
Bueno, AL; Goemann, IM; Larsen, PR; Maia, AL; Wajner, SM | 1 |
Friesema, EC; Klootwijk, W; Visser, TJ | 1 |
Darras, VM; Derde, S; Eerdekens, A; Güiza, F; Langouche, L; Mebis, L; Princen, L; Van den Berghe, G; Vanhorebeek, I; Vanwijngaerden, YM | 1 |
Lépine, M; Verreault, J | 1 |
96 other study(ies) available for dithiothreitol and thyroxine
Article | Year |
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Subcellular localization of a rat liver enzyme converting thyroxine into tri-iodothyronine and possible involvement of essential thiol groups.
Topics: 4-Chloromercuribenzenesulfonate; Cyanides; Dithiothreitol; Edetic Acid; Endoplasmic Reticulum; Glucose-6-Phosphatase; Liver; Mercury; Microsomes, Liver; NAD; NADP; Silver; Thyroxine; Triiodothyronine | 1976 |
Sequential deiodination of thyroxine in rat liver homogenate.
Topics: Animals; Chemical Phenomena; Chemistry; Diiodothyronines; Dithiothreitol; Edetic Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Propylthiouracil; Rats; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1978 |
High affinity thyroxine binding to purified rat liver plasma membranes.
Topics: Alanine; Animals; Calcium; Cell Membrane; Dithiothreitol; Edetic Acid; Ethylmaleimide; Hydroxymercuribenzoates; Kinetics; Liver; Magnesium; Male; Membrane Proteins; Rats; Receptors, Cell Surface; Thyroxine | 1979 |
Triiodothyronine binding to liver nuclear solubilized proteins in vitro.
Topics: Animals; Binding Sites; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Hot Temperature; Hydrogen-Ion Concentration; In Vitro Techniques; Kinetics; Liver; Male; Mercuribenzoates; Monoiodotyrosine; Nucleoproteins; Rats; Thyroxine; Time Factors; Triiodothyronine | 1975 |
The role of sulfhydryl groups on the impaired hepatic 3',3,5-triiodothyronine generation from thyroxine in the hypothyroid, starved, fetal, and neonatal rodent.
Topics: Aging; Animals; Animals, Newborn; Dithiothreitol; Female; Fetus; Hypothyroidism; Liver; Male; Mice; Pregnancy; Rats; Starvation; Sulfhydryl Compounds; Temperature; Thyroidectomy; Thyroxine; Triiodothyronine | 1979 |
Changes in the particulate subcellular component of hepatic thyroxine-5'-monodeiodinase in hyperthyroid and hypothyroid rats.
Topics: Animals; Dithiothreitol; Hyperthyroidism; Hypothyroidism; Iodide Peroxidase; Kinetics; Liver; Peroxidases; Rats; Subcellular Fractions; Thyroidectomy; Thyroxine; Triiodothyronine | 1979 |
Non-thyrotropic pituitary cells in culture convert T4 to T3.
Topics: Animals; Cell Line; Dithiothreitol; Kinetics; Pituitary Gland; Rats; Thyrotropin; Thyroxine; Triiodothyronine | 1979 |
Comparison of thyroxine and 3,3',5'-triiodothyronine metabolism in rat kidney and liver homogenates.
Topics: Animals; Diamide; Dinitrophenols; Dithiothreitol; Iopanoic Acid; Kidney; Liver; Male; Methimazole; Organ Specificity; Propylthiouracil; Rats; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1979 |
Sulfhydryl groups and the monodeiodination of thyroxine to triiodothyronine.
Topics: Animals; Dithiothreitol; Female; Fetus; Liver; Pregnancy; Rats; Sheep; Sulfhydryl Compounds; Sulfhydryl Reagents; Thyroxine; Triiodothyronine | 1978 |
L-triiodothyronine and L-reverse-triiodothyronine generation in the human polymorphonuclear leukocyte.
Topics: Adult; Dithiothreitol; Fetal Blood; Humans; Hypoxia; In Vitro Techniques; Infant, Newborn; Kinetics; Methimazole; Neutrophils; Phagocytosis; Propylthiouracil; Subcellular Fractions; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1978 |
Thyroxine to 3,5,3'-triiodothyronine conversion by rat anterior pituitary and liver.
Topics: Animals; Cell Nucleus; Dithiothreitol; Liver; Male; Pituitary Gland, Anterior; Rats; Thyroxine; Triiodothyronine | 1978 |
Subcellular distribution of thyroxine 5'-deiodinase in the rat kidney: a plasma membrane location.
Topics: Animals; Cell Membrane; Dithiothreitol; Iodide Peroxidase; Kidney; Male; Peroxidases; Rats; Subcellular Fractions; Thyroxine | 1978 |
Thyroxine 5'-deiodinase activity of rat kidney: observations on activation by thiols and inhibition by propylthiouracil.
Topics: Animals; Dithiothreitol; Enzyme Activation; Iodide Peroxidase; Kidney; Kinetics; Male; Peroxidases; Propylthiouracil; Rats; Sulfhydryl Compounds; Thyroxine | 1978 |
Evidence for the kidney as an important source of 5'-monodeiodination activity and stimulation by somatostatin in Oreochromis niloticus L.
Topics: Analysis of Variance; Animals; Dithiothreitol; Hot Temperature; In Vitro Techniques; Iodide Peroxidase; Kidney; Liver; Male; Propylthiouracil; Radioimmunoassay; Somatostatin; Thyroid Gland; Thyroxine; Tilapia; Time Factors; Triiodothyronine | 1992 |
Properties of T4 5'-deiodinating systems in various tissues of the rainbow trout, Oncorhynchus mykiss.
Topics: Animals; Dithiothreitol; Erythrocytes; Gills; Hydrogen-Ion Concentration; Iodide Peroxidase; Kidney; Microsomes, Liver; Muscles; Propylthiouracil; Thyroxine; Trout | 1992 |
Subcellular distribution of thyroxine 5'-monodeiodinase activity in rabbit kidney.
Topics: Animals; Cell Membrane; Cytosol; Dithiothreitol; Female; Iodide Peroxidase; Kidney; Kinetics; Microsomes; Microvilli; Mitochondria; Propylthiouracil; Rabbits; Subcellular Fractions; Thyroxine; Triiodothyronine | 1991 |
Ontogeny of hepatic bovine growth hormone receptors in cattle.
Topics: Aging; Animals; Binding, Competitive; Cattle; Dithiothreitol; Growth Hormone; Insulin; Insulin-Like Growth Factor I; Insulin-Like Growth Factor II; Least-Squares Analysis; Liver; Male; Microsomes, Liver; Prolactin; Receptors, Somatotropin; Recombinant Proteins; Thyroxine; Triiodothyronine | 1991 |
Induction of type II T4-5'-monodeiodinase activity in brown adipose tissue in fasted mice.
Topics: Adipose Tissue; Animals; Dithiothreitol; Enzyme Induction; Fasting; Female; Iodide Peroxidase; Kinetics; Mice; Propylthiouracil; Thyroxine; Triiodothyronine | 1990 |
Regulation of iodothyronine 5'-deiodinases: effects of thiol blockers and altered substrate levels in vivo and in vitro.
Topics: Adipose Tissue, Brown; Animals; Brain; Disulfides; Dithiothreitol; Ethanol; Homeostasis; Hypothyroidism; Iodide Peroxidase; Kidney; Microsomes; Pituitary Gland; Propylthiouracil; Rats; Sulfhydryl Reagents; Thyroxine | 1990 |
Presence of thyroxine 5'-monodeiodinase activity in kidney homogenates of the frog, Rana ridibunda.
Topics: Animals; Dithiothreitol; In Vitro Techniques; Iodide Peroxidase; Kidney; Male; Propylthiouracil; Radioimmunoassay; Rana ridibunda; Temperature; Thyroxine; Triiodothyronine | 1990 |
Iodothyronine deiodinase activities in FRTL5 cells: predominance of type I 5'-deiodinase.
Topics: Animals; Cell Line; Dithiothreitol; Iodide Peroxidase; Kinetics; Methimazole; Propylthiouracil; Rats; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1990 |
Ontogenic characterization of type I and II thyroxine 5'-monodeiodinases in brown adipose tissue from fetal and newborn rabbits.
Topics: Adipose Tissue, Brown; Age Factors; Amiodarone; Animals; Animals, Newborn; Dithiothreitol; Dose-Response Relationship, Drug; Fetus; Iodide Peroxidase; Iopanoic Acid; Propylthiouracil; Rabbits; Thyroxine; Triiodothyronine | 1990 |
In vitro studies of the effect of propylthiouracil and ronnel on thyroxine-5'-monodeiodinase activity in steers.
Topics: Animals; Cattle; Dithiothreitol; Food Additives; In Vitro Techniques; Iodide Peroxidase; Kidney; Liver; Male; Organothiophosphorus Compounds; Peroxidases; Propylthiouracil; Radioimmunoassay; Thyroxine; Triiodothyronine | 1985 |
A study of hepatic low Km iodothyronine 5'-monodeiodinase.
Topics: Animals; Dithiothreitol; Iodide Peroxidase; Ions; Kinetics; Liver; Rats; Thyroid Diseases; Thyroxine; Triiodothyronine | 1989 |
A study of hepatic metabolism of thyroxine in BB/W rats treated with L-thyroxine.
Topics: Animals; Diabetes Mellitus, Experimental; Dithiothreitol; Female; Liver; Male; Organ Size; Rats; Rats, Inbred Strains; Stereoisomerism; Sulfhydryl Compounds; Thyroxine; Triiodothyronine | 1989 |
Ligand-induced inactivation of type I iodothyronine 5'-deiodinase: protection by propylthiouracil in vivo and reversibility in vitro.
Topics: Animals; Dithiothreitol; Iodide Peroxidase; Kidney; Kinetics; Ligands; Male; Microsomes; Microsomes, Liver; Organ Specificity; Propylthiouracil; Rats; Rats, Inbred Strains; Reference Values; Thyroxine | 1989 |
The effect of free radicals on hepatic 5'-monodeiodination of thyroxine and 3,3',5'-triiodothyronine.
Topics: Adult; Aged; Animals; Butanols; Catalase; Dithiothreitol; Free Radicals; Humans; Iodide Peroxidase; Malondialdehyde; Microsomes, Liver; Middle Aged; Rats; Superoxide Dismutase; tert-Butyl Alcohol; Thiourea; Thyroxine; Triiodothyronine, Reverse; Vitamin E | 1987 |
Seasonal changes of the 5'-monodeiodination activity in kidney and skin homogenates of male Rana ridibunda: relation to plasma thyroxine (T4) and testosterone.
Topics: Animals; Dithiothreitol; Edetic Acid; In Vitro Techniques; Kidney; Liver; Male; Rana ridibunda; Ranidae; Seasons; Skin; Testosterone; Thyroxine; Triiodothyronine | 1987 |
The ontogeny of iodothyronine 5'-monodeiodinase activity in Rana catesbeiana tadpoles.
Topics: Animals; Dithiothreitol; Iodide Peroxidase; Kinetics; Metamorphosis, Biological; Muscles; Propylthiouracil; Rana catesbeiana; Skin; Thyroxine; Triiodothyronine | 1988 |
The effects and interactions of substrates, inhibitors, and the cellular thiol-disulfide balance on the regulation of type II iodothyronine 5'-deiodinase.
Topics: Animals; Cell Line; Cerebral Cortex; Cycloheximide; Diamide; Dithiothreitol; Hypothyroidism; Iopanoic Acid; Kinetics; Male; Parathyroid Glands; Pituitary Gland, Anterior; Pituitary Neoplasms; Rats; Rats, Inbred Strains; Thyroidectomy; Thyroxine; Triiodothyronine, Reverse | 1988 |
Effect of cortisol on the in vitro hepatic conversion of thyroxine to triiodothyronine in brook charr (Salvelinus fontinalis Mitchill).
Topics: Animals; Dithiothreitol; Hydrocortisone; Hydrogen-Ion Concentration; Liver; Temperature; Thyroxine; Triiodothyronine | 1988 |
Hormonal control of a low Km (type II) iodothyronine 5'-deiodinase in cultured NB41A3 mouse neuroblastoma cells.
Topics: Animals; Cell Line; Dexamethasone; Dithiothreitol; Epinephrine; Insulin; Iodide Peroxidase; Kinetics; Mice; Neuroblastoma; Sulfhydryl Compounds; Thyroid Hormones; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1986 |
Comparison of type I 5'-deiodination of thyroxine and of reverse-triiodothyronine in rat and chicken liver homogenates.
Topics: Animals; Chickens; Dithiothreitol; Iodide Peroxidase; Kinetics; Liver; Rats; Rats, Inbred Strains; Species Specificity; Substrate Specificity; Thyroxine; Triiodothyronine, Reverse | 1986 |
Effect of cadmium on T4 outer ring monodeiodination by rat liver.
Topics: Animals; Cadmium; Dithiothreitol; Female; In Vitro Techniques; Liver; Metallothionein; Propylthiouracil; Rats; Rats, Inbred Strains; Thyroxine; Triiodothyronine | 1987 |
Comparison of kidney and brown adipose tissue iodothyronine 5'-deiodinases.
Topics: Adipose Tissue, Brown; Animals; Dithiothreitol; Iodide Peroxidase; Kidney; Kinetics; Microsomes; Propylthiouracil; Rats; Thyroxine; Triiodothyronine | 1987 |
Familial dysalbuminaemic hyperthyroxinaemia: studies of albumin binding and implications for hormone action.
Topics: Blood Protein Disorders; Cell Nucleus; Dithiothreitol; Female; Humans; Lymphocytes; Male; Protein Binding; Serum Albumin; Sex Hormone-Binding Globulin; Thyroxine | 1986 |
Iodothyronine 5'-deiodinase in brown adipose tissue: thiol activation and propylthiouracil inhibition.
Topics: Adipose Tissue, Brown; Animals; Dithiothreitol; Enzyme Activation; Hypothyroidism; Iodide Peroxidase; Kidney; Kinetics; Male; Microsomes; Propylthiouracil; Rats; Thyroxine; Triiodothyronine, Reverse | 1986 |
Characteristics of thyroxine 5'-deiodinase activity in human liver.
Topics: Adolescent; Adult; Aged; Animals; Child; Child, Preschool; Dithiothreitol; Drug Stability; Female; Humans; In Vitro Techniques; Iodide Peroxidase; Liver; Male; Microsomes, Liver; Middle Aged; Propylthiouracil; Rats; Rats, Inbred Strains; Subcellular Fractions; Thyroxine; Time Factors; Triiodothyronine | 1986 |
In-vitro conversion of thyroxine to tri-iodothyronine by chicken hepatic 5'-deiodinase: kinetic studies.
Topics: Animals; Chickens; Culture Techniques; Dithiothreitol; Hydrogen-Ion Concentration; Iodide Peroxidase; Kinetics; Liver; Male; Temperature; Thyroxine; Triiodothyronine | 1986 |
Heterogeneity of thyroxine binding by serum albumins in normal subjects and patients with familial dysalbuminemic hyperthyroxinemia.
Topics: Alkylation; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Humans; Isoelectric Focusing; Oxidation-Reduction; Protein Binding; Serum Albumin; Sulfhydryl Compounds; Thyroxine; Thyroxine-Binding Proteins | 1985 |
Biochemical and ontogenic characterization of thyroxine 5'-monodeiodinase in brown adipose tissue from fetal and newborn lambs.
Topics: Adipose Tissue, Brown; Animals; Animals, Newborn; Dithiothreitol; Female; Gestational Age; Hydrogen-Ion Concentration; Iodide Peroxidase; Kinetics; Pregnancy; Propylthiouracil; Sheep; Sulfhydryl Compounds; Thyroxine; Triiodothyronine | 1986 |
The inner ring (5-) monodeiodination of thyroxine (T4) in cerebral cortex during fetal, neonatal, and adult life.
Topics: Aging; Animals; Cerebral Cortex; Dithiothreitol; Fasting; Female; Fetus; Hydrogen-Ion Concentration; Hyperthyroidism; Hypothyroidism; In Vitro Techniques; Iodine; Kinetics; Male; Pregnancy; Rats; Rats, Inbred Strains; Thyroxine; Triiodothyronine, Reverse | 1986 |
The mechanism of low serum T3 in the fetus: hepatic T4-5'-monodeiodinase versus tissue sulfhydryl content--a clarification.
Topics: Animals; Dithiothreitol; Female; Fetal Blood; Iodide Peroxidase; Liver; Pregnancy; Sheep; Sulfhydryl Compounds; Thyroxine; Triiodothyronine | 1986 |
Thyroid hormone metabolism in primary cultures of fetal rat brain cells.
Topics: Animals; Cells; Cells, Cultured; Cerebral Cortex; Chemical Phenomena; Chemistry; Dithiothreitol; Fetus; Iodide Peroxidase; Rats; Rats, Inbred Strains; Thyroid Hormones; Thyroxine; Triiodothyronine | 1985 |
Rapid and selective inner ring deiodination of thyroxine sulfate by rat liver deiodinase.
Topics: Animals; Diiodothyronines; Dithiothreitol; Iodide Peroxidase; Iodine Radioisotopes; Kinetics; Microsomes, Liver; Peroxidases; Propylthiouracil; Rats; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1985 |
Skin is an active site for the inner ring monodeiodination of thyroxine to 3,3',5'-triiodothyronine.
Topics: Animals; Dithiothreitol; Fasting; Female; Hydrogen-Ion Concentration; Hyperthyroidism; Hypothyroidism; Male; Microsomes; Pregnancy; Propylthiouracil; Rats; Skin; Temperature; Thyroxine; Time Factors; Tissue Distribution; Triiodothyronine, Reverse | 1985 |
Subcellular localization of thyroxine 5'-deiodinase activity in bovine anterior pituitary.
Topics: Animals; Cattle; Centrifugation, Density Gradient; Dithiothreitol; Female; Hydrogen-Ion Concentration; Iodide Peroxidase; Kinetics; Male; Microscopy, Electron; Pituitary Gland, Anterior; Subcellular Fractions; Thyroxine; Triiodothyronine | 1985 |
Methionine metabolism in mammals: synthesis of S-adenosylhomocysteine in rat tissues.
Topics: Adenosine; Animals; Carbon Radioisotopes; Chromatography, Ion Exchange; Chromatography, Paper; Cysteine; Dithiothreitol; Glucagon; Glutathione; Growth Hormone; Homocysteine; Hydrocortisone; Isotope Labeling; Liver; Male; Methionine; Organ Specificity; Rats; S-Adenosylmethionine; Thyroxine; Tritium | 1973 |
Inhibition by coumadin anticoagulants of enzymatic outer ring monodeiodination of iodothyronines.
Topics: Animals; Binding, Competitive; Dicumarol; Dithiothreitol; Iodide Peroxidase; Kidney; Male; Microsomes; Peroxidases; Propylthiouracil; Rats; Thyroxine; Triiodothyronine, Reverse; Warfarin | 1982 |
Uptake, metabolism and subcellular distribution of [125I]T4 in calf thyroid slices.
Topics: Animals; Cattle; Cell Nucleus; Chromatography, Paper; Dithiothreitol; Iopanoic Acid; Mercaptoethanol; Potassium Iodide; Propylthiouracil; Protein Biosynthesis; RNA; Subcellular Fractions; Thyroid Gland; Thyroxine; Trichloroacetic Acid | 1984 |
Triiodothyronine production by isolated rat hepatocytes: characterization and lack of glucoregulatory hormone effects.
Topics: 2,4-Dinitrophenol; Animals; Dinitrophenols; Dithiothreitol; Glucagon; Glucose; Insulin; Liver; Male; Propylthiouracil; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1984 |
Maturational changes in the regulatory mechanisms of hepatic thyroxine 5'-monodeiodination in growing rats.
Topics: Age Factors; Animals; Diamide; Dithiothreitol; Edetic Acid; Female; Glutathione; Iodide Peroxidase; Iodoacetamide; Liver; Methylene Blue; NADP; Peroxidases; Propylthiouracil; Rats; Rats, Inbred Strains; Thyroxine; Triiodothyronine | 1983 |
Iodothyronine 5'-deiodinase in rat kidney microsomes. Kinetic behavior at low substrate concentrations.
Topics: Animals; Binding Sites; Dithiothreitol; Glutathione; Iodide Peroxidase; Iopanoic Acid; Kidney; Kinetics; Microsomes; Peroxidases; Propylthiouracil; Rats; Substrate Specificity; Temperature; Thioctic Acid; Thyroxine; Triiodothyronine, Reverse | 1984 |
Evaluation of thyroxine monodeiodination to reverse triiodothyronine by tissue homogenates in vitro.
Topics: Animals; Dithiothreitol; Hydrogen-Ion Concentration; In Vitro Techniques; Iodide Peroxidase; Kidney; Liver; Swine; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1983 |
Kinetics of hepatic thyroxine 5'-deiodinase.
Topics: Animals; Dithiothreitol; Iodide Peroxidase; Kinetics; Male; Microsomes, Liver; Rats; Rats, Inbred Strains; Thyroxine; Triiodothyronine | 1983 |
Monodeiodination of thyroxine to 3,3',5'-triiodothyronine in the human placenta.
Topics: Dithiothreitol; Female; Hot Temperature; Humans; Hydrogen-Ion Concentration; Iodine; Microsomes; Placenta; Pregnancy; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1983 |
Monodeiodination of thyroxine to 3, 5, 3'-triiodothyronine and to 3, 3', 5'-triiodothyronine in isolated dog renal cortical tubuli.
Topics: Animals; Dithiothreitol; Dogs; Hydrogen-Ion Concentration; In Vitro Techniques; Kidney Cortex; Kidney Tubules; Temperature; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1983 |
Inner ring deiodination of thyroxine and 3,5,3'-triiodothyronine by human fetal membranes.
Topics: Amnion; Chorion; Dithiothreitol; Extraembryonic Membranes; Female; Humans; Hydrogen-Ion Concentration; Iodide Peroxidase; Iodine Radioisotopes; Pregnancy; Temperature; Thyroxine; Time Factors; Triiodothyronine; Triiodothyronine, Reverse | 1983 |
Phenolic and tyrosyl ring deiodination in thyroxine from rat retina during postnatal development.
Topics: Animals; Dithiothreitol; Female; In Vitro Techniques; Iodide Peroxidase; Male; Propylthiouracil; Radioimmunoassay; Rats; Rats, Inbred Strains; Retina; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1984 |
Thyroid hormone metabolism in cultured monkey hepatocarcinoma cells. Monodeiodination activity in relation to cell growth.
Topics: Animals; Cell Cycle; Cells, Cultured; Culture Media; Diiodothyronines; Dithiothreitol; Haplorhini; Iodide Peroxidase; Kinetics; Liver Neoplasms, Experimental; Thyroid Hormones; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1980 |
Familial euthyroid thyroxine excess: characterization of abnormal intermediate affinity thyroxine binding to albumin.
Topics: Barbital; Binding Sites; Binding, Competitive; Dialysis; Dithiothreitol; Humans; Serum Albumin; Thyroxine; Thyroxine-Binding Proteins; Triiodothyronine | 1982 |
Evidence for two pathways of iodothyronine 5'-deiodination in rat pituitary that differ in kinetics, propylthiouracil sensitivity, and response to hypothyroidism.
Topics: Animals; Depression, Chemical; Dithiothreitol; Hypothyroidism; Iodide Peroxidase; Kinetics; Male; Microsomes; Peroxidases; Pituitary Gland, Anterior; Propylthiouracil; Rats; Rats, Inbred Strains; Thyroidectomy; Thyroxine; Triiodothyronine | 1983 |
Characteristics of iodothyronine tyrosyl ring deiodination by rat cerebral cortical microsomes.
Topics: Animals; Cerebral Cortex; Chemical Phenomena; Chemistry; Dithiothreitol; Hydrogen-Ion Concentration; Kinetics; Male; Mathematics; Microsomes; Rats; Rats, Inbred Strains; Thyroxine; Triiodothyronine | 1983 |
Preincubation of thyroxine with sulfhydryl-reducing agents does not stimulate thyroxine inner or outer ring deiodination.
Topics: Animals; Dithiothreitol; Female; Humans; Iodine; Liver; Male; Placenta; Pregnancy; Rats; Rats, Inbred Strains; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1983 |
Triiodothyronine generation from thyroxine in human thyroid: enhanced conversion in Graves' thyroid tissue.
Topics: Adenoma; Carcinoma; Dithiothreitol; Graves Disease; Humans; Hydrogen-Ion Concentration; Kinetics; Thyroid Gland; Thyroid Neoplasms; Thyroxine; Triiodothyronine | 1981 |
Effect of sulfhydryl reagents on the conversion of thyroxine to 3,5,3'-triiodothyronine: direct action on thyroxine molecules.
Topics: Animals; Dithiothreitol; Glutathione; Kinetics; Liver; Mercaptoethanol; Rats; Rats, Inbred Strains; Sulfhydryl Reagents; Thyroxine; Triiodothyronine | 1982 |
Outer and inner ring monodeiodination of thyroxine by dog thyroid and liver: a comparative study using a particulate cell fraction.
Topics: Animals; Dithiothreitol; Dogs; Iodide Peroxidase; Ipodate; Kinetics; Microsomes, Liver; Propylthiouracil; Temperature; Thyroid Gland; Thyroxine; Time Factors; Triiodothyronine; Triiodothyronine, Reverse | 1982 |
Human placenta is an active site of thyroxine and 3,3'5-triiodothyronine tyrosyl ring deiodination.
Topics: Diiodothyronines; Dithiothreitol; Female; Humans; Kinetics; Placenta; Pregnancy; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1981 |
Evidence of an altered 5'-monodeiodinase for thyroxine in the liver of the fetal rabbit.
Topics: Aging; Animals; Dithiothreitol; Female; In Vitro Techniques; Kinetics; Liver; Microsomes, Liver; Rabbits; Thyroxine; Triiodothyronine | 1981 |
Inner ring monodeiodination of thyroxine and 3,5,3'-L-triiodothyronine in rat brain.
Topics: Aging; Animals; Animals, Newborn; Brain; Diiodothyronines; Dithiothreitol; Fetus; Kinetics; Male; Propylthiouracil; Rats; Rats, Inbred Strains; Subcellular Fractions; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1981 |
Placental inner ring iodothyronine deiodination: a mechanism for decreased passage of T4 and T3 from mother to fetus.
Topics: Animals; Dithiothreitol; Female; Fetus; Maternal-Fetal Exchange; Placenta; Pregnancy; Rats; Rats, Inbred Strains; Thyroxine; Triiodothyronine | 1981 |
Characterization of essential enzyme sulfhydryl groups of thyroxine 5'-deiodinase from rat kidney.
Topics: Animals; Cell Membrane; Dithiothreitol; Ethylmaleimide; Humans; Iodide Peroxidase; Kidney; Kinetics; Peroxidases; Propylthiouracil; Protein Binding; Rats; Subcellular Fractions; Sulfhydryl Reagents; Thyroxine | 1980 |
Thyroxine 5'-monodeiodination in rat anterior pituitary homogenates.
Topics: Animals; Dithiothreitol; Fasting; Glutathione; Kinetics; Male; Pituitary Gland, Anterior; Rats; Thyrotropin; Thyroxine; Triiodothyronine | 1980 |
Alterations in monodeiodination of iodothyronines in the fasting rat: effects of reduced nonprotein sulfhydryl groups and hypothyroidism.
Topics: Animals; Diiodothyronines; Dithiothreitol; Fasting; Hypothyroidism; Iodine; Liver; Male; Rats; Sulfhydryl Compounds; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse | 1980 |
Divergent changes of thyroxine-5'-monodeiodination in rat pituitary and liver during maturation.
Topics: Aging; Animals; Cell Nucleus; Dithiothreitol; Female; Liver; Male; Organ Specificity; Pituitary Gland; Rats; Thyrotropin; Thyroxine; Triiodothyronine | 1980 |
Phenolic and tyrosyl ring deiodination of iodothyronines in rat brain homogenates.
Topics: Animals; Brain; Dithiothreitol; Hydrogen-Ion Concentration; Hyperthyroidism; Hypothyroidism; In Vitro Techniques; Iodine; Iopanoic Acid; Male; Rats; Subcellular Fractions; Temperature; Thyronines; Thyroxine; Time; Triiodothyronine | 1980 |
A possible function of thiols, including glutathione, as cofactors in the conversion of thyroxine to 3,3',5-triiodothyronine in rat liver microsomes.
Topics: Animals; Chromatography, Gel; Dithiothreitol; Enzyme Activation; Glutathione; Iodide Peroxidase; Male; Microsomes, Liver; Rats; Thyroxine; Triiodothyronine | 1980 |
[A study of the conversion of thyroxine to 3, 3', 5-triiodothyronine in the rat liver: the mechanism of stimulatory effects of thiols on T4 5'-deiodinase (author's transl)].
Topics: Animals; Dithiothreitol; Glutathione; Iodide Peroxidase; Liver; Male; Microsomes; Peroxidases; Rats; Sulfhydryl Compounds; Sulfhydryl Reagents; Thyroxine; Triiodothyronine | 1980 |
Changes in hepatic iodothyronine metabolism during ontogeny of the chick embryo.
Topics: Animals; Chick Embryo; Diiodothyronines; Dithiothreitol; Hydrocortisone; Kinetics; Liver; Thyronines; Thyroxine; Triiodothyronine, Reverse | 1980 |
Iodothyronine deiodinase activity in methionine-deficient rats fed selenium-deficient or selenium-sufficient diets.
Topics: Animals; Body Weight; Diet; Dithiothreitol; Glutathione; Glutathione Peroxidase; Indicators and Reagents; Iodide Peroxidase; Male; Methionine; Organ Size; Rats; Rats, Wistar; Selenium; Selenomethionine; Thyroxine; Triiodothyronine | 1995 |
Changes induced by cadmium administration on thyroxine deiodination and sulfhydryl groups in rat liver.
Topics: Animals; Cadmium; Cadmium Chloride; Chlorides; Dithionitrobenzoic Acid; Dithiothreitol; In Vitro Techniques; Iodide Peroxidase; Liver; Male; Rats; Rats, Wistar; Sulfhydryl Compounds; Thyroxine; Triiodothyronine | 1993 |
Binding and degradation of 3,5,3'-triiodothyronine and thyroxine by rat intestinal bacteria.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Bacteria; Binding, Competitive; Dithiothreitol; Hot Temperature; Hydrogen-Ion Concentration; Intestines; Light; Male; Propylthiouracil; Rats; Rats, Sprague-Dawley; Reference Values; Serum Albumin; Thyroxine; Triiodothyronine | 1993 |
5' Deiodinase activity in brain regions of adult rats: modifications in different situations of experimental hypothyroidism.
Topics: Animals; Body Weight; Brain; Cytosol; Diet; Dithiothreitol; Glycerolphosphate Dehydrogenase; Hypothyroidism; Iodide Peroxidase; Liver; Malate Dehydrogenase; Male; Methimazole; Mitochondria, Liver; Propylthiouracil; Rats; Rats, Wistar; Thyroxine; Triiodothyronine | 1993 |
Thyroid hormone deiodination pathways in brain and liver of rainbow trout, Oncorhynchus mykiss.
Topics: Animals; Brain Chemistry; Chromatography, High Pressure Liquid; Dithiothreitol; Female; Hydrogen-Ion Concentration; Iodine; Kinetics; Liver; Male; Microsomes; Oncorhynchus mykiss; Sulfhydryl Reagents; Thyroid Hormones; Thyroxine; Triiodothyronine | 1996 |
Characterization of iodothyronine outer ring and inner ring deiodinase activities in the blue tilapia, Oreochromis aureus.
Topics: Animals; Dithiothreitol; Enzyme Inhibitors; Hydrogen-Ion Concentration; Iodide Peroxidase; Kidney; Kinetics; Liver; Rats; Species Specificity; Substrate Specificity; Thyroxine; Tilapia; Triiodothyronine; Triiodothyronine, Reverse | 1997 |
A role for thyroid hormones in the regulation of diet-induced thermogenesis in birds.
Topics: Animals; Body Temperature Regulation; Body Weight; Cell Nucleus; Chickens; Dithiothreitol; Eating; Iodide Peroxidase; Liver; Male; Receptors, Thyroid Hormone; Thyroxine; Triiodothyronine | 1997 |
Efflux of T4 from the in situ perfused liver of rainbow trout: effect of T4, dithiothreitol and cysteine in the perfusate.
Topics: Animals; Cysteine; Dithiothreitol; Kinetics; Liver; Oncorhynchus mykiss; Perfusion; Thyroxine | 1999 |
Deiodination activity in extrathyroidal tissues of the atlantic hagfish, Myxine glutinosa.
Topics: Animals; Aurothioglucose; Brain; Chromatography, High Pressure Liquid; Dithiothreitol; Enzyme Inhibitors; Female; Hagfishes; Intestinal Mucosa; Iodine; Iodoacetates; Liver; Male; Microsomes, Liver; Muscle, Skeletal; Propylthiouracil; Thyroid Gland; Thyroxine; Triiodothyronine | 2000 |
A selenium-containing catalytic antibody with Type I deiodinase activity.
Topics: Amino Acid Substitution; Animals; Antibodies, Catalytic; Antibodies, Monoclonal; Dithiothreitol; Haptens; Iodide Peroxidase; Kinetics; Mice; Mice, Inbred BALB C; Propylthiouracil; Selenocysteine; Serine; Thyroxine | 2001 |
Characterization of outer ring iodothyronine deiodinases in tissues of the saltwater crocodile (Crocodylus porosus).
Topics: Alligators and Crocodiles; Animals; Dithiothreitol; Enzyme Inhibitors; Iodide Peroxidase; Kinetics; Microsomes; Proteins; Seawater; Substrate Specificity; Sulfhydryl Reagents; Temperature; Thyroxine; Tissue Distribution; Triiodothyronine | 2002 |
Substitution of cysteine for a conserved alanine residue in the catalytic center of type II iodothyronine deiodinase alters interaction with reducing cofactor.
Topics: Alanine; Amino Acid Substitution; Animals; Catalysis; COS Cells; Cysteine; Dithiothreitol; Genetic Vectors; Humans; Iodide Peroxidase; Iodothyronine Deiodinase Type II; Kinetics; Mutagenesis, Site-Directed; Mutation; Oxidation-Reduction; Selenocysteine; Thyroxine; Triiodothyronine | 2002 |
Substitution of serine for proline in the active center of type 2 iodothyronine deiodinase substantially alters its in vitro biochemical properties with dithiothreitol but not its function in intact cells.
Topics: Amino Acid Substitution; Catalytic Domain; Cell Line; Dithiothreitol; Glutathione; Humans; Iodide Peroxidase; Kidney; Kinetics; Liver; Proline; Propylthiouracil; Serine; Thyroxine; Transfection | 2010 |
IL-6 promotes nonthyroidal illness syndrome by blocking thyroxine activation while promoting thyroid hormone inactivation in human cells.
Topics: Acetylcysteine; Cell Line; Cell Line, Tumor; Cytokines; Dithiothreitol; Glutathione; Humans; Interleukin-6; Oxidative Stress; Reactive Oxygen Species; RNA, Messenger; Thyroid Diseases; Thyroid Hormones; Thyroxine | 2011 |
A nonselenoprotein from amphioxus deiodinates triac but not T3: is triac the primordial bioactive thyroid hormone?
Topics: Amino Acid Sequence; Animals; Base Sequence; Chordata, Nonvertebrate; Dithiothreitol; Iodide Peroxidase; Molecular Sequence Data; Thyroxine; Triiodothyronine | 2011 |
Contribution of nutritional deficit to the pathogenesis of the nonthyroidal illness syndrome in critical illness: a rabbit model study.
Topics: Animals; Constitutive Androstane Receptor; Critical Illness; Disease Models, Animal; Dithiothreitol; Euthyroid Sick Syndromes; Gene Expression Regulation; Hypothalamo-Hypophyseal System; Iodide Peroxidase; Leptin; Male; Nutrition Disorders; Parenteral Nutrition Solutions; Rabbits; Random Allocation; Receptors, Cytoplasmic and Nuclear; Thyroid Gland; Thyrotropin-Releasing Hormone; Thyroxine; Triiodothyronine | 2012 |
Biotransformation of Dec-604 and potential effect on thyroid deiodinase activity in highly flame retardant-exposed gulls.
Topics: Animals; Biotransformation; Charadriiformes; Dithiothreitol; Flame Retardants; Halogenated Diphenyl Ethers; Iodide Peroxidase; Thyroid Gland; Thyroxine | 2022 |