Page last updated: 2024-08-22

dithiothreitol and propylthiouracil

dithiothreitol has been researched along with propylthiouracil in 60 studies

Research

Studies (60)

TimeframeStudies, this research(%)All Research%
pre-199034 (56.67)18.7374
1990's20 (33.33)18.2507
2000's5 (8.33)29.6817
2010's1 (1.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Docter, R; Fekkes, D; Hennemann, G; Visser, TJ1
Breitbart, R; Kaplan, MM; Larsen, PR; Tatro, JB1
Woeber, KA1
Leonard, JL; Rosenberg, IN3
Byamungu, N; Kühn, ER; Mol, K1
Imura, H; Shimatsu, A; Tanaka, K1
Eales, JG; MacLatchy, DL1
McNabb, FM; Rieman, JD1
Galton, VA; McCarthy, PT; St Germain, DL1
Asano, Y; Kusano, E; Murayama, N; Sakurada, T; Yamaki, M; Yoshida, K1
Florsheim, W; Parker, LN; Wright, C; Wu, SY1
Goswami, A; Rosenberg, IN5
Jacobs, GF; Kühn, ER1
Borges, M; Ingbar, SH; Silva, JE1
Brzezińska-Slebodzińska, E; Kapluk, J1
Hummel, BC; Takagi, S; Walfish, PG1
Ikeda, H; Itagaki, Y; Kaise, K; Kaise, N; Sakurada, T; Yamamoto, M; Yoshida, K; Yoshinaga, K1
Bitman, J; Kahl, S; Rumsey, TS1
Croteau, W; St Germain, DL1
Biassoni, R; Vaccari, A1
Galton, VA; Hiebert, A1
Saito, H; Saito, S; Sakurada, T; Sugihira, N; Suzuki, M; Yoshida, K; Yoshinaga, K1
Larsen, PR; Mellen, S; Silva, JE1
Hardy, JJ; Thomas, CL; Utiger, RD1
Fisher, DA; Polk, DH; Wu, SY1
Mol, JA; Visser, TJ1
Beredo, A; Chopra, IJ; Huang, TS; Solomon, DH1
Braverman, LE; Emerson, CH; Gambino, J; Nogimori, T; Wright, GE; Wu, CF1
Koerner, D; Oppenheimer, JH; Surks, MI1
Goswami, A; Leonard, JL; Rosenberg, IN1
Chazenbalk, GD; Juvenal, GJ; Kleiman de Pisarev, DL; Pisarev, MA1
Utiger, RD1
Kajiwara, S; Kato, T; Kita, K; Miyamori, C; Sato, T1
Braverman, LE; Emerson, CH; Fang, SL; Fay, M; Roti, E; Wright, G1
Di Giorgio, RM; Ientile, R; Macaione, S; Pugliese, G; Russo, P1
Balsam, A; Eisenstein, Z; Garber, JR; Ingbar, SH1
Kaplan, MM; Larsen, PR; Leonard, JL; Visser, TJ1
Boye, N; Laurberg, P1
Burman, KD; Dimond, RC; Latham, KR; Smallridge, RC; Ward, KE; Wartofsky, L; Wright, FD1
Imura, H; Inada, M; Ishii, H; Mashio, Y; Naito, K; Nishikawa, M; Tanaka, K1
Cooper, DS; Maloof, F; Ridgway, EC; Saxe, VC1
Goglia, F; Horst, C; Lanni, A; Moreno, M; Thoma, R1
de Luze, A; DiStefano, JJ; Nguyen, TT1
Imura, H; Tanaka, K1
Montiel, M; Morata, P; Morell, M; Serrano-Lozano, A1
Orozco, A; Silva, JE; Valverde-R, C1
Berry, MJ; Harney, JW; Larsen, PR; Sun, BC1
De Herder, WW; den Hollander, JC; Hume, R; Kaptein, E; Krenning, EP; Richard, K; Sanders, JP; van Toor, H; Visser, TJ1
Fenton, B; Valverde-R, C1
Eales, JG; McLeese, JM; Wright, GM; Youson, JH1
Chen, M; Ding, L; Lian, G; Liu, Z; Ni, J; Zhao, D1
Chen, M; Ding, L; Lian, G; Liu, L; Ni, J; Zhao, D1
Li, H; McKinnon, B; Mortimer, RH; Richard, K1
Gereben, B; Goemann, IM; Harney, JW; Larsen, PR; Maia, AL; Zhu, B1

Other Studies

60 other study(ies) available for dithiothreitol and propylthiouracil

ArticleYear
Sequential deiodination of thyroxine in rat liver homogenate.
    The Biochemical journal, 1978, Jul-15, Volume: 174, Issue:1

    Topics: Animals; Chemical Phenomena; Chemistry; Diiodothyronines; Dithiothreitol; Edetic Acid; Hydrogen-Ion Concentration; In Vitro Techniques; Liver; Propylthiouracil; Rats; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse

1978
Comparison of thyroxine and 3,3',5'-triiodothyronine metabolism in rat kidney and liver homogenates.
    Metabolism: clinical and experimental, 1979, Volume: 28, Issue:11

    Topics: Animals; Diamide; Dinitrophenols; Dithiothreitol; Iopanoic Acid; Kidney; Liver; Male; Methimazole; Organ Specificity; Propylthiouracil; Rats; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse

1979
L-triiodothyronine and L-reverse-triiodothyronine generation in the human polymorphonuclear leukocyte.
    The Journal of clinical investigation, 1978, Volume: 62, Issue:3

    Topics: Adult; Dithiothreitol; Fetal Blood; Humans; Hypoxia; In Vitro Techniques; Infant, Newborn; Kinetics; Methimazole; Neutrophils; Phagocytosis; Propylthiouracil; Subcellular Fractions; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse

1978
Thyroxine 5'-deiodinase activity of rat kidney: observations on activation by thiols and inhibition by propylthiouracil.
    Endocrinology, 1978, Volume: 103, Issue:6

    Topics: Animals; Dithiothreitol; Enzyme Activation; Iodide Peroxidase; Kidney; Kinetics; Male; Peroxidases; Propylthiouracil; Rats; Sulfhydryl Compounds; Thyroxine

1978
Evidence for the kidney as an important source of 5'-monodeiodination activity and stimulation by somatostatin in Oreochromis niloticus L.
    General and comparative endocrinology, 1992, Volume: 88, Issue:2

    Topics: Analysis of Variance; Animals; Dithiothreitol; Hot Temperature; In Vitro Techniques; Iodide Peroxidase; Kidney; Liver; Male; Propylthiouracil; Radioimmunoassay; Somatostatin; Thyroid Gland; Thyroxine; Tilapia; Time Factors; Triiodothyronine

1992
Iodothyronine 5-deiodinase in rat posterior pituitary.
    Biochemical and biophysical research communications, 1992, Oct-15, Volume: 188, Issue:1

    Topics: Animals; beta-Endorphin; Chromatography, High Pressure Liquid; Dithiothreitol; Iodide Peroxidase; Isoenzymes; Kinetics; Male; Pituitary Gland, Anterior; Pituitary Gland, Posterior; Propylthiouracil; Rats; Rats, Wistar; Thyroid Hormones

1992
Properties of T4 5'-deiodinating systems in various tissues of the rainbow trout, Oncorhynchus mykiss.
    General and comparative endocrinology, 1992, Volume: 86, Issue:2

    Topics: Animals; Dithiothreitol; Erythrocytes; Gills; Hydrogen-Ion Concentration; Iodide Peroxidase; Kidney; Microsomes, Liver; Muscles; Propylthiouracil; Thyroxine; Trout

1992
Assay validation and characterization of hepatic 5'-deiodinase activity in ring doves using reverse-T3 as substrate.
    General and comparative endocrinology, 1991, Volume: 82, Issue:1

    Topics: Animals; Columbidae; Dithiothreitol; Iodide Peroxidase; Kinetics; Liver; Propylthiouracil; Substrate Specificity; Temperature; Triiodothyronine; Triiodothyronine, Reverse

1991
The ontogeny of iodothyronine deiodinase systems in liver and intestine of the rat.
    Endocrinology, 1991, Volume: 128, Issue:4

    Topics: Aging; Animals; Dithiothreitol; Enzyme Activation; Female; Glutathione; Intestines; Iodide Peroxidase; Iopanoic Acid; Kinetics; Liver; Propylthiouracil; Rats

1991
Subcellular distribution of thyroxine 5'-monodeiodinase activity in rabbit kidney.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1991, Volume: 23, Issue:1

    Topics: Animals; Cell Membrane; Cytosol; Dithiothreitol; Female; Iodide Peroxidase; Kidney; Kinetics; Microsomes; Microvilli; Mitochondria; Propylthiouracil; Rabbits; Subcellular Fractions; Thyroxine; Triiodothyronine

1991
Induction of type II T4-5'-monodeiodinase activity in brown adipose tissue in fasted mice.
    The American journal of the medical sciences, 1990, Volume: 299, Issue:1

    Topics: Adipose Tissue; Animals; Dithiothreitol; Enzyme Induction; Fasting; Female; Iodide Peroxidase; Kinetics; Mice; Propylthiouracil; Thyroxine; Triiodothyronine

1990
Regulation of iodothyronine 5'-deiodinases: effects of thiol blockers and altered substrate levels in vivo and in vitro.
    Endocrinology, 1990, Volume: 126, Issue:5

    Topics: Adipose Tissue, Brown; Animals; Brain; Disulfides; Dithiothreitol; Ethanol; Homeostasis; Hypothyroidism; Iodide Peroxidase; Kidney; Microsomes; Pituitary Gland; Propylthiouracil; Rats; Sulfhydryl Reagents; Thyroxine

1990
Presence of thyroxine 5'-monodeiodinase activity in kidney homogenates of the frog, Rana ridibunda.
    General and comparative endocrinology, 1990, Volume: 77, Issue:3

    Topics: Animals; Dithiothreitol; In Vitro Techniques; Iodide Peroxidase; Kidney; Male; Propylthiouracil; Radioimmunoassay; Rana ridibunda; Temperature; Thyroxine; Triiodothyronine

1990
Iodothyronine deiodinase activities in FRTL5 cells: predominance of type I 5'-deiodinase.
    Endocrinology, 1990, Volume: 126, Issue:6

    Topics: Animals; Cell Line; Dithiothreitol; Iodide Peroxidase; Kinetics; Methimazole; Propylthiouracil; Rats; Thyroid Gland; Thyrotropin; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse

1990
Ontogenic characterization of type I and II thyroxine 5'-monodeiodinases in brown adipose tissue from fetal and newborn rabbits.
    Biology of the neonate, 1990, Volume: 57, Issue:6

    Topics: Adipose Tissue, Brown; Age Factors; Amiodarone; Animals; Animals, Newborn; Dithiothreitol; Dose-Response Relationship, Drug; Fetus; Iodide Peroxidase; Iopanoic Acid; Propylthiouracil; Rabbits; Thyroxine; Triiodothyronine

1990
Thionamides and arsenite inhibit specific T3 binding to the hepatic nuclear receptor.
    Biochemistry and cell biology = Biochimie et biologie cellulaire, 1990, Volume: 68, Issue:3

    Topics: Animals; Arsenic; Arsenites; Cell Nucleus; Chromatography, Liquid; Dithiothreitol; Liver; Methimazole; Methyl Methanesulfonate; Propylthiouracil; Rats; Receptors, Thyroid Hormone; Sodium Compounds; Sulfhydryl Reagents; Triiodothyronine

1990
Thyroxine 5'-deiodinase in human anterior pituitary tumors.
    The Journal of clinical endocrinology and metabolism, 1990, Volume: 71, Issue:2

    Topics: Acromegaly; Adult; Dithiothreitol; Female; Humans; Iodide Peroxidase; Kinetics; Male; Middle Aged; Pituitary Gland, Anterior; Pituitary Neoplasms; Prolactin; Propylthiouracil

1990
In vitro studies of the effect of propylthiouracil and ronnel on thyroxine-5'-monodeiodinase activity in steers.
    Journal of animal science, 1985, Volume: 61, Issue:1

    Topics: Animals; Cattle; Dithiothreitol; Food Additives; In Vitro Techniques; Iodide Peroxidase; Kidney; Liver; Male; Organothiophosphorus Compounds; Peroxidases; Propylthiouracil; Radioimmunoassay; Thyroxine; Triiodothyronine

1985
Ligand-induced inactivation of type I iodothyronine 5'-deiodinase: protection by propylthiouracil in vivo and reversibility in vitro.
    Endocrinology, 1989, Volume: 125, Issue:5

    Topics: Animals; Dithiothreitol; Iodide Peroxidase; Kidney; Kinetics; Ligands; Male; Microsomes; Microsomes, Liver; Organ Specificity; Propylthiouracil; Rats; Rats, Inbred Strains; Reference Values; Thyroxine

1989
Selective effects of thiol reagents on the binding sites for imipramine and neurotransmitter amines in the rat brain.
    British journal of pharmacology, 1985, Volume: 85, Issue:2

    Topics: Animals; Brain; Carrier Proteins; Dithionitrobenzoic Acid; Dithiothreitol; Ethylmaleimide; Hydroxymercuribenzoates; Imipramine; Male; Mercaptoethanol; Methimazole; Propylthiouracil; Rats; Receptors, Dopamine; Receptors, Drug; Receptors, Neurotransmitter; Serotonin; Spiperone; Sulfhydryl Reagents

1985
Iodothyronine 5'-deiodination in rat kidney microsomes: sensitivity to propylthiouracil.
    Endocrinology, 1988, Volume: 123, Issue:6

    Topics: Animals; Dithiothreitol; Enzyme Activation; Iodide Peroxidase; Iopanoic Acid; Kidney; Kinetics; Microsomes; Propylthiouracil; Rats; Triiodothyronine, Reverse

1988
The ontogeny of iodothyronine 5'-monodeiodinase activity in Rana catesbeiana tadpoles.
    Endocrinology, 1988, Volume: 122, Issue:2

    Topics: Animals; Dithiothreitol; Iodide Peroxidase; Kinetics; Metamorphosis, Biological; Muscles; Propylthiouracil; Rana catesbeiana; Skin; Thyroxine; Triiodothyronine

1988
Effect of cadmium on T4 outer ring monodeiodination by rat liver.
    Environmental research, 1987, Volume: 42, Issue:2

    Topics: Animals; Cadmium; Dithiothreitol; Female; In Vitro Techniques; Liver; Metallothionein; Propylthiouracil; Rats; Rats, Inbred Strains; Thyroxine; Triiodothyronine

1987
Comparison of kidney and brown adipose tissue iodothyronine 5'-deiodinases.
    Endocrinology, 1987, Volume: 121, Issue:2

    Topics: Adipose Tissue, Brown; Animals; Dithiothreitol; Iodide Peroxidase; Kidney; Kinetics; Microsomes; Propylthiouracil; Rats; Thyroxine; Triiodothyronine

1987
Iodothyronine 5'-deiodinase in brown adipose tissue: thiol activation and propylthiouracil inhibition.
    Endocrinology, 1986, Volume: 119, Issue:2

    Topics: Adipose Tissue, Brown; Animals; Dithiothreitol; Enzyme Activation; Hypothyroidism; Iodide Peroxidase; Kidney; Kinetics; Male; Microsomes; Propylthiouracil; Rats; Thyroxine; Triiodothyronine, Reverse

1986
Characteristics of thyroxine 5'-deiodinase activity in human liver.
    The American journal of the medical sciences, 1986, Volume: 292, Issue:4

    Topics: Adolescent; Adult; Aged; Animals; Child; Child, Preschool; Dithiothreitol; Drug Stability; Female; Humans; In Vitro Techniques; Iodide Peroxidase; Liver; Male; Microsomes, Liver; Middle Aged; Propylthiouracil; Rats; Rats, Inbred Strains; Subcellular Fractions; Thyroxine; Time Factors; Triiodothyronine

1986
Biochemical and ontogenic characterization of thyroxine 5'-monodeiodinase in brown adipose tissue from fetal and newborn lambs.
    Endocrinology, 1986, Volume: 118, Issue:4

    Topics: Adipose Tissue, Brown; Animals; Animals, Newborn; Dithiothreitol; Female; Gestational Age; Hydrogen-Ion Concentration; Iodide Peroxidase; Kinetics; Pregnancy; Propylthiouracil; Sheep; Sulfhydryl Compounds; Thyroxine; Triiodothyronine

1986
Rapid and selective inner ring deiodination of thyroxine sulfate by rat liver deiodinase.
    Endocrinology, 1985, Volume: 117, Issue:1

    Topics: Animals; Diiodothyronines; Dithiothreitol; Iodide Peroxidase; Iodine Radioisotopes; Kinetics; Microsomes, Liver; Peroxidases; Propylthiouracil; Rats; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse

1985
Skin is an active site for the inner ring monodeiodination of thyroxine to 3,3',5'-triiodothyronine.
    Endocrinology, 1985, Volume: 117, Issue:5

    Topics: Animals; Dithiothreitol; Fasting; Female; Hydrogen-Ion Concentration; Hyperthyroidism; Hypothyroidism; Male; Microsomes; Pregnancy; Propylthiouracil; Rats; Skin; Temperature; Thyroxine; Time Factors; Tissue Distribution; Triiodothyronine, Reverse

1985
Synthesis of 6-anilino-2-thiouracils and their inhibition of human placenta iodothyronine deiodinase.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:11

    Topics: Chemical Phenomena; Chemistry; Dithiothreitol; Female; Humans; Iodide Peroxidase; Placenta; Pregnancy; Propylthiouracil; Structure-Activity Relationship; Thiouracil

1985
In vitro formation of apparent covalent complexes between L-triiodothyronine and plasma protein.
    The Journal of clinical endocrinology and metabolism, 1973, Volume: 36, Issue:2

    Topics: Blood Proteins; Chromatography, Paper; Copper; Dithiothreitol; Flavin Mononucleotide; Glutathione; Humans; In Vitro Techniques; Iodine Isotopes; Pronase; Propylthiouracil; Protein Binding; Sodium Dodecyl Sulfate; Thiosulfates; Triiodothyronine; Urea

1973
Inhibition by coumadin anticoagulants of enzymatic outer ring monodeiodination of iodothyronines.
    Biochemical and biophysical research communications, 1982, Feb-26, Volume: 104, Issue:4

    Topics: Animals; Binding, Competitive; Dicumarol; Dithiothreitol; Iodide Peroxidase; Kidney; Male; Microsomes; Peroxidases; Propylthiouracil; Rats; Thyroxine; Triiodothyronine, Reverse; Warfarin

1982
Stimulation of iodothyronine outer ring monodeiodinase by dihydrolipoamide.
    Endocrinology, 1983, Volume: 112, Issue:4

    Topics: Animals; Dicumarol; Dithiothreitol; Enzyme Activation; Iodide Peroxidase; Kidney; Kinetics; Microsomes; NAD; Peroxidases; Propylthiouracil; Rats; Temperature; Thioctic Acid

1983
Uptake, metabolism and subcellular distribution of [125I]T4 in calf thyroid slices.
    Acta endocrinologica, 1984, Volume: 105, Issue:3

    Topics: Animals; Cattle; Cell Nucleus; Chromatography, Paper; Dithiothreitol; Iopanoic Acid; Mercaptoethanol; Potassium Iodide; Propylthiouracil; Protein Biosynthesis; RNA; Subcellular Fractions; Thyroid Gland; Thyroxine; Trichloroacetic Acid

1984
Triiodothyronine production by isolated rat hepatocytes: characterization and lack of glucoregulatory hormone effects.
    Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme, 1984, Volume: 16 Suppl 1

    Topics: 2,4-Dinitrophenol; Animals; Dinitrophenols; Dithiothreitol; Glucagon; Glucose; Insulin; Liver; Male; Propylthiouracil; Rats; Rats, Inbred Strains; Serum Albumin, Bovine; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse

1984
Maturational changes in the regulatory mechanisms of hepatic thyroxine 5'-monodeiodination in growing rats.
    Pediatric research, 1983, Volume: 17, Issue:7

    Topics: Age Factors; Animals; Diamide; Dithiothreitol; Edetic Acid; Female; Glutathione; Iodide Peroxidase; Iodoacetamide; Liver; Methylene Blue; NADP; Peroxidases; Propylthiouracil; Rats; Rats, Inbred Strains; Thyroxine; Triiodothyronine

1983
Iodothyronine 5'-deiodinase in rat kidney microsomes. Kinetic behavior at low substrate concentrations.
    The Journal of clinical investigation, 1984, Volume: 74, Issue:6

    Topics: Animals; Binding Sites; Dithiothreitol; Glutathione; Iodide Peroxidase; Iopanoic Acid; Kidney; Kinetics; Microsomes; Peroxidases; Propylthiouracil; Rats; Substrate Specificity; Temperature; Thioctic Acid; Thyroxine; Triiodothyronine, Reverse

1984
The effects of propylthiouracil, iodothyronines, and other agents on thyroid hormone metabolism in human placenta.
    The Journal of clinical endocrinology and metabolism, 1984, Volume: 58, Issue:2

    Topics: Animals; Biological Transport; Cytosol; Dithiothreitol; Humans; Hydrogen-Ion Concentration; Iodide Peroxidase; Kinetics; Microsomes; Placenta; Propylthiouracil; Rats; Thyroid Hormones; Thyronines

1984
Phenolic and tyrosyl ring deiodination in thyroxine from rat retina during postnatal development.
    European journal of biochemistry, 1984, Jul-02, Volume: 142, Issue:1

    Topics: Animals; Dithiothreitol; Female; In Vitro Techniques; Iodide Peroxidase; Male; Propylthiouracil; Radioimmunoassay; Rats; Rats, Inbred Strains; Retina; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse

1984
A study of the properties of the enzyme in rat liver that deiodinates 3,3'5'-triiodothyronine to 3,3'-diiodothyronine.
    Endocrinology, 1980, Volume: 107, Issue:2

    Topics: Animals; Diiodothyronines; Dithiothreitol; Edetic Acid; Hyperthyroidism; Hypothyroidism; Iodide Peroxidase; Kinetics; Liver; Male; NADP; Peroxidases; Propylthiouracil; Rats; Starvation; Thyroidectomy; Thyronines; Triiodothyronine; Triiodothyronine, Reverse

1980
Evidence for two pathways of iodothyronine 5'-deiodination in rat pituitary that differ in kinetics, propylthiouracil sensitivity, and response to hypothyroidism.
    The Journal of clinical investigation, 1983, Volume: 71, Issue:4

    Topics: Animals; Depression, Chemical; Dithiothreitol; Hypothyroidism; Iodide Peroxidase; Kinetics; Male; Microsomes; Peroxidases; Pituitary Gland, Anterior; Propylthiouracil; Rats; Rats, Inbred Strains; Thyroidectomy; Thyroxine; Triiodothyronine

1983
Outer and inner ring monodeiodination of thyroxine by dog thyroid and liver: a comparative study using a particulate cell fraction.
    Endocrinology, 1982, Volume: 110, Issue:6

    Topics: Animals; Dithiothreitol; Dogs; Iodide Peroxidase; Ipodate; Kinetics; Microsomes, Liver; Propylthiouracil; Temperature; Thyroid Gland; Thyroxine; Time Factors; Triiodothyronine; Triiodothyronine, Reverse

1982
3',5'-diiodothyronine to 3'-monoiodothyronine conversion in the fed and fasted rat: enzyme characteristics and evidence for two distinct 5'-deiodinases.
    Endocrinology, 1981, Volume: 108, Issue:6

    Topics: Animals; Diiodothyronines; Dithiothreitol; Fasting; Hydrogen-Ion Concentration; Iodide Peroxidase; Kidney; Kinetics; Male; Microsomes; Microsomes, Liver; Peroxidases; Propylthiouracil; Rats; Temperature; Thyronines

1981
Inner ring monodeiodination of thyroxine and 3,5,3'-L-triiodothyronine in rat brain.
    Endocrinology, 1981, Volume: 109, Issue:5

    Topics: Aging; Animals; Animals, Newborn; Brain; Diiodothyronines; Dithiothreitol; Fetus; Kinetics; Male; Propylthiouracil; Rats; Rats, Inbred Strains; Subcellular Fractions; Thyroxine; Triiodothyronine; Triiodothyronine, Reverse

1981
Characterization of essential enzyme sulfhydryl groups of thyroxine 5'-deiodinase from rat kidney.
    Endocrinology, 1980, Volume: 106, Issue:2

    Topics: Animals; Cell Membrane; Dithiothreitol; Ethylmaleimide; Humans; Iodide Peroxidase; Kidney; Kinetics; Peroxidases; Propylthiouracil; Protein Binding; Rats; Subcellular Fractions; Sulfhydryl Reagents; Thyroxine

1980
Iodothyronine 5'-deiodinase from rat kidney: substrate specificity and the 5'-deiodination of reverse triiodothyronine.
    Endocrinology, 1980, Volume: 107, Issue:5

    Topics: Animals; Dithiothreitol; Intracellular Membranes; Iodide Peroxidase; Iodides; Iodoacetates; Kidney; Kinetics; Microsomes; Peroxidases; Propylthiouracil; Rats; Substrate Specificity; Triiodothyronine; Triiodothyronine, Reverse

1980
Studies of propylthiouracil using a newly developed radioimmunoassay.
    The Journal of clinical endocrinology and metabolism, 1981, Volume: 52, Issue:2

    Topics: Adult; Dithiothreitol; Drug Stability; Electrophoresis, Polyacrylamide Gel; Female; Half-Life; Humans; Kinetics; Male; Middle Aged; Propylthiouracil; Radioimmunoassay; Sodium Dodecyl Sulfate

1981
In vitro binding of 3,5-di-iodo-L-thyronine to rat liver mitochondria.
    Journal of molecular endocrinology, 1994, Volume: 13, Issue:3

    Topics: Adenosine Triphosphate; Animals; Binding Sites; Cell Fractionation; Diiodothyronines; Dithiothreitol; Hydrogen-Ion Concentration; Kinetics; Liver; Male; Mitochondria, Liver; Propylthiouracil; Protein Binding; Rats; Rats, Wistar; Receptors, Thyroid Hormone; Temperature

1994
Binding and degradation of 3,5,3'-triiodothyronine and thyroxine by rat intestinal bacteria.
    The American journal of physiology, 1993, Volume: 264, Issue:6 Pt 1

    Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Bacteria; Binding, Competitive; Dithiothreitol; Hot Temperature; Hydrogen-Ion Concentration; Intestines; Light; Male; Propylthiouracil; Rats; Rats, Sprague-Dawley; Reference Values; Serum Albumin; Thyroxine; Triiodothyronine

1993
Iodothyronine 5'-deiodinase is present in mouse sublingual gland.
    Endocrinology, 1993, Volume: 132, Issue:3

    Topics: Animals; Binding, Competitive; Dithiothreitol; Hydrogen-Ion Concentration; Iodide Peroxidase; Kinetics; Liver; Male; Mice; Mice, Inbred Strains; Organ Specificity; Propylthiouracil; Sublingual Gland; Submandibular Gland; Substrate Specificity

1993
5' Deiodinase activity in brain regions of adult rats: modifications in different situations of experimental hypothyroidism.
    Brain research bulletin, 1993, Volume: 30, Issue:5-6

    Topics: Animals; Body Weight; Brain; Cytosol; Diet; Dithiothreitol; Glycerolphosphate Dehydrogenase; Hypothyroidism; Iodide Peroxidase; Liver; Malate Dehydrogenase; Male; Methimazole; Mitochondria, Liver; Propylthiouracil; Rats; Rats, Wistar; Thyroxine; Triiodothyronine

1993
Rainbow trout liver expresses two iodothyronine phenolic ring deiodinase pathways with the characteristics of mammalian types I and II 5'-deiodinases.
    Endocrinology, 1997, Volume: 138, Issue:1

    Topics: Animals; Dithiothreitol; Iodide Peroxidase; Kinetics; Liver; Oncorhynchus mykiss; Propylthiouracil

1997
The role of the active site cysteine in catalysis by type 1 iodothyronine deiodinase.
    Endocrinology, 1997, Volume: 138, Issue:12

    Topics: Amino Acid Sequence; Animals; Catalysis; Conserved Sequence; Cysteine; Dithiothreitol; Glutathione; Iodide Peroxidase; Iodine; Isoenzymes; Molecular Sequence Data; Mutation; Osmolar Concentration; Propylthiouracil; Rats

1997
Ontogeny of iodothyronine deiodinases in human liver.
    The Journal of clinical endocrinology and metabolism, 1998, Volume: 83, Issue:8

    Topics: Adult; Blotting, Northern; Chromatography, High Pressure Liquid; Dithiothreitol; Female; Gestational Age; Humans; Infant, Newborn; Infant, Premature; Iodide Peroxidase; Kinetics; Liver; Male; Microsomes, Liver; Middle Aged; Pregnancy; Propylthiouracil; Triiodothyronine; Triiodothyronine, Reverse

1998
Hepatic outer-ring deiodinase in a Mexican endemic lizard (Sceloporus grammicus).
    General and comparative endocrinology, 2000, Volume: 117, Issue:1

    Topics: Animals; Aurothioglucose; Dithiothreitol; Enzyme Inhibitors; Female; Hydrogen-Ion Concentration; Iodide Peroxidase; Kinetics; Liver; Lizards; Male; Pregnancy; Propylthiouracil; Seasons; Sex Characteristics; Temperature; Triiodothyronine, Reverse

2000
Deiodination activity in extrathyroidal tissues of the atlantic hagfish, Myxine glutinosa.
    The Journal of experimental zoology, 2000, Nov-01, Volume: 287, Issue:6

    Topics: Animals; Aurothioglucose; Brain; Chromatography, High Pressure Liquid; Dithiothreitol; Enzyme Inhibitors; Female; Hagfishes; Intestinal Mucosa; Iodine; Iodoacetates; Liver; Male; Microsomes, Liver; Muscle, Skeletal; Propylthiouracil; Thyroid Gland; Thyroxine; Triiodothyronine

2000
Preparation and properties of a selenium-containing catalytic antibody as type I deiodinase mimic.
    The Journal of biological chemistry, 2001, Jul-27, Volume: 276, Issue:30

    Topics: Animals; Antibodies; Antibodies, Monoclonal; Binding, Competitive; Catalysis; Catalytic Domain; Dithiothreitol; Electrophoresis, Polyacrylamide Gel; Enzyme-Linked Immunosorbent Assay; Haptens; Humans; Hybridomas; Iodide Peroxidase; Kinetics; Mice; Mice, Inbred BALB C; Models, Chemical; Propylthiouracil; Radioimmunoassay; Selenium; Tumor Cells, Cultured

2001
A selenium-containing catalytic antibody with Type I deiodinase activity.
    Biochemical and biophysical research communications, 2001, May-25, Volume: 283, Issue:5

    Topics: Amino Acid Substitution; Animals; Antibodies, Catalytic; Antibodies, Monoclonal; Dithiothreitol; Haptens; Iodide Peroxidase; Kinetics; Mice; Mice, Inbred BALB C; Propylthiouracil; Selenocysteine; Serine; Thyroxine

2001
Effect of Iodide on Human Choriogonadotropin, Sodium-Iodide Symporter Expression, and Iodide Uptake in BeWo Choriocarcinoma Cells.
    The Journal of clinical endocrinology and metabolism, 2007, Volume: 92, Issue:10

    Topics: Antithyroid Agents; Cell Line, Tumor; Choriocarcinoma; Chorionic Gonadotropin; Dithiothreitol; Female; Gene Expression; Humans; Iodine; Iodine Radioisotopes; Propylthiouracil; RNA, Messenger; Symporters; Thyroid Gland; Trace Elements; Trophoblasts; Uterine Neoplasms

2007
Substitution of serine for proline in the active center of type 2 iodothyronine deiodinase substantially alters its in vitro biochemical properties with dithiothreitol but not its function in intact cells.
    Endocrinology, 2010, Volume: 151, Issue:2

    Topics: Amino Acid Substitution; Catalytic Domain; Cell Line; Dithiothreitol; Glutathione; Humans; Iodide Peroxidase; Kidney; Kinetics; Liver; Proline; Propylthiouracil; Serine; Thyroxine; Transfection

2010