Page last updated: 2024-08-22

dithiothreitol and methotrexate

dithiothreitol has been researched along with methotrexate in 12 studies

Research

Studies (12)

TimeframeStudies, this research(%)All Research%
pre-19906 (50.00)18.7374
1990's0 (0.00)18.2507
2000's2 (16.67)29.6817
2010's4 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kaufman, S; Milstien, S1
Jansen, G; Rijksen, G; Schornagel, JH; Westerhof, GR1
Blair, AH; Ghose, T; Uadia, PO1
Hultin, TA; Weber, WW1
Kalman, TI1
Henderson, GB; Zevely, EM1
Abbondandolo, A; Bonatti, S; Bozzo, S; Campomenosi, P; Fronza, G; Lane, DP; Miele, M; Moro, F; Ottaggio, L; Sparks, A1
Courteau, J; Kocsis-Bédard, S; Niyonsenga, T; Paquette, B; Thibodeau, PA1
Shen, Y; Sui, M; Tang, J; Wang, X; Xu, J1
Chen, Y; Fang, C; Feng, W; Peng, S; Wang, W; Wang, X; Wang, Y; Yan, C; Zhao, M1
Bian, S; Fan, Y; Huang, Y; Liang, J; Sun, Y; Zhang, X1
Yang, HK; Zhang, LM1

Other Studies

12 other study(ies) available for dithiothreitol and methotrexate

ArticleYear
Studies on the phenylalanine hydroxylase system in liver slices.
    The Journal of biological chemistry, 1975, Jun-25, Volume: 250, Issue:12

    Topics: Animals; Ascorbic Acid; Dithiothreitol; Fenclonine; Folic Acid Antagonists; Glutathione; In Vitro Techniques; Kinetics; Liver; Mercaptoethanol; Methotrexate; Phenylalanine; Phenylalanine Hydroxylase; Rats; Structure-Activity Relationship; Time Factors

1975
Interaction of N-hydroxy(sulfo) succinimide active esters with the reduced folate/methotrexate transport system from human leukemic CCRF-CEM cells.
    Biochimica et biophysica acta, 1989, Nov-03, Volume: 985, Issue:3

    Topics: Biological Transport; Cell Membrane; Cross-Linking Reagents; Dithiothreitol; Folic Acid; Humans; Leukemia; Methotrexate; Succinimides; Tumor Cells, Cultured

1989
Hydrolysis of methotrexate-immunoglobulin conjugates by liver homogenates and characterization of catabolites.
    Cancer chemotherapy and pharmacology, 1988, Volume: 22, Issue:2

    Topics: Antipain; Dithiothreitol; Humans; Hydrogen-Ion Concentration; Hydrolysis; Immunoglobulins; Liver; Methotrexate; Tetrahydrofolate Dehydrogenase; Tosyllysine Chloromethyl Ketone

1988
Genetic differences in inhibition of 2-aminofluorene N-acetyltransferase activity between C57BL/6J and A/J mice.
    Biochemical pharmacology, 1986, Apr-01, Volume: 35, Issue:7

    Topics: 2-Acetylaminofluorene; 4-Aminobenzoic Acid; Acetyltransferases; Animals; Arylamine N-Acetyltransferase; Dithiothreitol; Fluorenes; Folic Acid; Kinetics; Male; Methotrexate; Mice; Mice, Inbred A; Mice, Inbred C57BL

1986
Inhibition of thymidylate synthetase by showdomycin and its 5'-phosphate.
    Biochemical and biophysical research communications, 1972, Nov-15, Volume: 49, Issue:4

    Topics: Dithiothreitol; Drug Resistance, Microbial; Hydrogenation; Lacticaseibacillus casei; Maleimides; Mercaptoethanol; Methotrexate; Methyltransferases; Protein Binding; Ribonucleosides; Ribonucleotides; Spectrophotometry; Sulfhydryl Reagents; Thymidylate Synthase; Time Factors; Uracil Nucleotides

1972
Transport of methotrexate in L1210 cells. Mechanism for inhibition by p-chloromercuriphenylsulfonate and N-ethylmaleimide.
    Biochimica et biophysica acta, 1981, Jan-22, Volume: 640, Issue:2

    Topics: 4-Chloromercuribenzenesulfonate; Animals; Biological Transport; Carrier Proteins; Cell Line; Dithiothreitol; Dose-Response Relationship, Drug; Ethylmaleimide; Leukemia L1210; Methotrexate; Mice; Phenylmercury Compounds

1981
Defective nuclear localization of p53 protein in a Chinese hamster cell line is associated with the formation of stable cytoplasmic protein multimers in cells with gene amplification.
    Carcinogenesis, 2000, Volume: 21, Issue:9

    Topics: 3T3 Cells; Animals; Antimetabolites, Antineoplastic; Burkitt Lymphoma; Cell Line, Transformed; Cell Nucleus; Cricetinae; Cricetulus; Cytoplasm; Dithiothreitol; DNA; Drug Resistance, Neoplasm; Gene Amplification; Humans; Immunoblotting; Methotrexate; Mice; Phenotype; Phosphorylation; Precipitin Tests; Sodium Dodecyl Sulfate; Tetrahydrofolate Dehydrogenase; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2000
Thiols can either enhance or suppress DNA damage induction by catecholestrogens.
    Free radical biology & medicine, 2001, Jan-01, Volume: 30, Issue:1

    Topics: Acetylcysteine; Antioxidants; Copper; Dithiothreitol; DNA Damage; Drug Resistance, Neoplasm; Estradiol; Estrogens, Catechol; Glutathione; Hydrogen Peroxide; Kinetics; Methotrexate; NAD; Oxidation-Reduction; Reactive Oxygen Species; Sulfhydryl Compounds; Thioctic Acid

2001
Degradable water soluble hyperbranched polymers for drug delivery.
    Journal of controlled release : official journal of the Controlled Release Society, 2011, Nov-30, Volume: 152 Suppl 1

    Topics: Acrylates; Animals; Antineoplastic Agents; Camptothecin; Cell Survival; Cells, Cultured; Chemistry, Pharmaceutical; Dithiothreitol; Dose-Response Relationship, Drug; Drug Carriers; Drug Compounding; Glycerides; Humans; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Inhibitory Concentration 50; Kinetics; Magnetic Resonance Spectroscopy; Methotrexate; Molecular Structure; Particle Size; Polyethylene Glycols; Solubility; Technology, Pharmaceutical; Water

2011
Modifying mesoporous silica nanoparticles to avoid the metabolic deactivation of 6-mercaptopurine and methotrexate in combinatorial chemotherapy.
    Nanoscale, 2013, Jul-21, Volume: 5, Issue:14

    Topics: Cell Proliferation; Dithiothreitol; Endocytosis; Humans; K562 Cells; Mercaptopurine; Metal Nanoparticles; Methotrexate; Neoplasms; Porosity; Silicon Dioxide; Surface Properties

2013
Reduction-degradable PEG-b-PAA-b-PEG triblock copolymer micelles incorporated with MTX for cancer chemotherapy.
    Colloids and surfaces. B, Biointerfaces, 2013, Dec-01, Volume: 112

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Dithiothreitol; Drug Carriers; Hep G2 Cells; Humans; KB Cells; Magnetic Resonance Spectroscopy; Methotrexate; Micelles; Neoplasms; Nylons; Oxidation-Reduction; Particle Size; Polyamines; Polyethylene Glycols; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization; Spectroscopy, Fourier Transform Infrared

2013
New amphiphilic glycopolypeptide conjugate capable of self-assembly in water into reduction-sensitive micelles for triggered drug release.
    Materials science & engineering. C, Materials for biological applications, 2014, Aug-01, Volume: 41

    Topics: Antineoplastic Agents; Click Chemistry; Dextrans; Dithiothreitol; Drug Carriers; Glycopeptides; Methotrexate; Micelles; Water

2014
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