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dithiothreitol and ebselen

dithiothreitol has been researched along with ebselen in 15 studies

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (40.00)18.2507
2000's7 (46.67)29.6817
2010's2 (13.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cotgreave, IA; Engman, L; Morgenstern, R1
Hayaishi, O; Islam, F; Morii, H; Watanabe, Y1
Christison, J; Sies, H; Stocker, R1
Furuhama, K; Ogasawara, T; Tabuchi, Y1
Aoyama, T; Hattori, R; Inoue, R; Kawai, C; Masayasu, H; Sasayama, S; Shinoda, E; Yui, Y1
Kazuki, S; Miyamoto, T; Ogawa, R; Ohta, T; Takase, T; Tamura, Y; Tsuji, M1
Holmgren, A; Zhao, R1
Borges, VC; Nogueira, CW; Rocha, JB; Zeni, G1
Biswas, KK; Hashiguchi, T; Lee, KY; Maruyama, I; Rosales, JL; Sarker, KP; Yamaji, K1
Ghisleni, G; Porciúncula, LO; Rocha, JB; Souza, DO; Tavares, RG1
Borges, VC; Nogueira, CW; Rocha, JB1
Godinho, G; Moretto, MB; Nogueira, CW; Rocha, JB; Roessler, TM; Souza, DO; Thomazi, AP; Wofchuk, S1
Coelho, IS; Dafre, AL; Franco, JL; Meotti, FC; Rocha, JB; Santos, AR1
Lugokenski, TH; Müller, LG; Pereira, ME; Rocha, JB; Taube, PS1
Balogun, BD; Kade, IJ; Rocha, JB1

Other Studies

15 other study(ies) available for dithiothreitol and ebselen

ArticleYear
Determination of the relative contributions of the diselenide and selenol forms of ebselen in the mechanism of its glutathione peroxidase-like activity.
    Chemico-biological interactions, 1992, Sep-14, Volume: 84, Issue:1

    Topics: Anilides; Azoles; Benzamides; Dithiothreitol; Glutathione; Glutathione Peroxidase; Hydrogen Peroxide; Isoindoles; Kinetics; Organoselenium Compounds; Selenium; Selenium Compounds

1992
Inhibition of rat brain prostaglandin D synthase by inorganic selenocompounds.
    Archives of biochemistry and biophysics, 1991, Aug-15, Volume: 289, Issue:1

    Topics: Animals; Azoles; Brain; Chlorides; Cyclooxygenase Inhibitors; Dithiothreitol; Dose-Response Relationship, Drug; Isoindoles; Kinetics; Male; Metals; Organoselenium Compounds; Rats; Rats, Inbred Strains; Selenious Acid; Selenium; Selenium Compounds; Sulfur

1991
Human blood cells support the reduction of low-density-lipoprotein-associated cholesteryl ester hydroperoxides by albumin-bound ebselen.
    The Biochemical journal, 1994, Dec-01, Volume: 304 ( Pt 2)

    Topics: Adult; Azoles; Blood Cells; Cholesterol; Cholesterol Esters; Cholesterol, LDL; Dithiothreitol; Female; Glutathione; Glutathione Peroxidase; Humans; Isoindoles; Male; Organoselenium Compounds; Oxidation-Reduction; Serum Albumin

1994
Mechanism of the inhibition of hog gastric H+,K(+)-ATPase by the seleno-organic compound ebselen.
    Arzneimittel-Forschung, 1994, Volume: 44, Issue:1

    Topics: 4-Nitrophenylphosphatase; Animals; Anti-Ulcer Agents; Azoles; Dithiothreitol; Fluorescein-5-isothiocyanate; Gastric Mucosa; Isoindoles; Organoselenium Compounds; Phosphorylation; Protein Conformation; Proton Pump Inhibitors; Spectrometry, Fluorescence; Swine

1994
Effect of ebselen on bovine and rat nitric oxide synthase activity is modified by thiols.
    Japanese journal of pharmacology, 1996, Volume: 72, Issue:2

    Topics: Animals; Aorta; Azoles; Cattle; Dithiothreitol; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Isoindoles; Macrophages, Peritoneal; Nitric Oxide Synthase; Organoselenium Compounds; Rats; Sulfhydryl Reagents

1996
Effect of ebselen on contractile responses in perfused rabbit basilar artery.
    Neurosurgery, 1999, Volume: 44, Issue:2

    Topics: Animals; Antioxidants; Azoles; Basilar Artery; Diglycerides; Dithiothreitol; Drug Synergism; Endothelin-1; Hydroxyl Radical; In Vitro Techniques; Isoindoles; Male; Organoselenium Compounds; Osmolar Concentration; Oxidoreductases; Oxyhemoglobins; Perfusion; Potassium; Rabbits; Sulfhydryl Reagents; Vasoconstriction; Vasoconstrictor Agents

1999
A novel antioxidant mechanism of ebselen involving ebselen diselenide, a substrate of mammalian thioredoxin and thioredoxin reductase.
    The Journal of biological chemistry, 2002, Oct-18, Volume: 277, Issue:42

    Topics: Animals; Antioxidants; Azoles; Benzamides; Cattle; Dithiothreitol; Escherichia coli; Glutathione; Humans; Hydrogen Peroxide; Isoindoles; Kinetics; Models, Chemical; Organoselenium Compounds; Placenta; Protein Binding; Spectrometry, Fluorescence; Thioredoxin-Disulfide Reductase; Thioredoxins; Time Factors

2002
Organochalcogens effects on delta-aminolevulinate dehydratase activity from human erythrocytic cells in vitro.
    Toxicology, 2003, Sep-30, Volume: 191, Issue:2-3

    Topics: Antioxidants; Azoles; Benzene Derivatives; Cysteine; Disulfides; Dithiothreitol; Drug Interactions; Erythrocytes; Glutathione Transferase; Humans; Isoindoles; Organometallic Compounds; Organoselenium Compounds; Porphobilinogen Synthase; Zinc

2003
Ebselen inhibits NO-induced apoptosis of differentiated PC12 cells via inhibition of ASK1-p38 MAPK-p53 and JNK signaling and activation of p44/42 MAPK and Bcl-2.
    Journal of neurochemistry, 2003, Volume: 87, Issue:6

    Topics: Animals; Annexin A5; Apoptosis; Azoles; Blotting, Western; Butadienes; Caspase 3; Caspases; Cell Differentiation; Cell Survival; Chaperonin 60; Cyclooxygenase Inhibitors; Cytochromes c; Dithiothreitol; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Activation; Enzyme Inhibitors; In Vitro Techniques; Isoindoles; JNK Mitogen-Activated Protein Kinases; MAP Kinase Kinase Kinase 5; MAP Kinase Kinase Kinases; Mitogen-Activated Protein Kinases; Nerve Growth Factor; Nitric Oxide; Nitric Oxide Donors; Nitriles; Nitroprusside; Organoselenium Compounds; p38 Mitogen-Activated Protein Kinases; PC12 Cells; Propidium; Proto-Oncogene Proteins c-bcl-2; Rats; Serine; Sodium Selenite; Time Factors; Transfection; Tumor Suppressor Protein p53; Vitamin E

2003
The effects of ebselen on [3H]glutamate uptake by synaptic vesicles from rat brain.
    Brain research, 2004, Nov-19, Volume: 1027, Issue:1-2

    Topics: Animals; Antioxidants; Azoles; Biological Transport; Brain; Dithiothreitol; Dose-Response Relationship, Drug; Fluorescein; Glutamates; Isoindoles; Organoselenium Compounds; Rats; Sodium-Potassium-Exchanging ATPase; Synaptic Vesicles; Synaptosomes; Tritium

2004
Effect of diphenyl diselenide, diphenyl ditelluride and ebselen on cerebral Na(+), K(+)-ATPase activity in rats.
    Toxicology, 2005, Nov-15, Volume: 215, Issue:3

    Topics: Animals; Azoles; Benzene Derivatives; Brain; Dithiothreitol; Dose-Response Relationship, Drug; Drug Antagonism; Enzyme Inhibitors; Isoindoles; Male; Neuroprotective Agents; Organometallic Compounds; Organoselenium Compounds; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase

2005
Ebselen and diorganylchalcogenides decrease in vitro glutamate uptake by rat brain slices: prevention by DTT and GSH.
    Toxicology in vitro : an international journal published in association with BIBRA, 2007, Volume: 21, Issue:4

    Topics: Aging; Animals; Antidotes; Azoles; Benzene Derivatives; Brain; Brain Chemistry; Cerebral Cortex; Chalcogens; Dithiothreitol; Glutamic Acid; Glutathione; In Vitro Techniques; Isoindoles; Male; Organometallic Compounds; Organoselenium Compounds; Rats; Rats, Wistar

2007
Redox modulation at the peripheral site alters nociceptive transmission in vivo.
    Clinical and experimental pharmacology & physiology, 2009, Volume: 36, Issue:3

    Topics: Alkylating Agents; Analgesics; Animals; Azoles; Behavior, Animal; Buthionine Sulfoximine; Disease Models, Animal; Dithiothreitol; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Glutamate-Cysteine Ligase; Glutamic Acid; Glutathione; Iodoacetates; Isoindoles; Mice; Organoselenium Compounds; Oxidation-Reduction; Pain; Receptors, N-Methyl-D-Aspartate; Reducing Agents; Signal Transduction; Sulfhydryl Compounds

2009
Inhibitory effect of ebselen on lactate dehydrogenase activity from mammals: a comparative study with diphenyl diselenide and diphenyl ditelluride.
    Drug and chemical toxicology, 2011, Volume: 34, Issue:1

    Topics: Animals; Antioxidants; Azoles; Benzene Derivatives; Biomarkers; Dithiothreitol; Dose-Response Relationship, Drug; Heart; Isoindoles; L-Lactate Dehydrogenase; Liver; Male; Molecular Structure; Myocardium; Organometallic Compounds; Organoselenium Compounds; Rats; Sulfhydryl Compounds

2011
In vitro glutathione peroxidase mimicry of ebselen is linked to its oxidation of critical thiols on key cerebral suphydryl proteins - A novel component of its GPx-mimic antioxidant mechanism emerging from its thiol-modulated toxicology and pharmacology.
    Chemico-biological interactions, 2013, Oct-25, Volume: 206, Issue:1

    Topics: Animals; Antioxidants; Azoles; Cerebrum; Dithiothreitol; Glutathione Peroxidase; Isoindoles; L-Lactate Dehydrogenase; Male; Mice; Molecular Mimicry; Molecular Structure; Organoselenium Compounds; Oxidation-Reduction; Porphobilinogen Synthase; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase; Structure-Activity Relationship

2013