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dithiothreitol and buthionine sulfoximine

dithiothreitol has been researched along with buthionine sulfoximine in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19901 (4.35)18.7374
1990's10 (43.48)18.2507
2000's9 (39.13)29.6817
2010's2 (8.70)24.3611
2020's1 (4.35)2.80

Authors

AuthorsStudies
Cammarata, PR; Tse, D; Yorio, T1
Darrow, RM; Morgan, MS; Nafz, MA; Varandani, PT1
Bootman, MD; Casteels, R; De Smedt, H; Droogmans, G; Missiaen, L; Parys, JB1
Cordier, A; Diez-Fernandez, C; Prieto, P; Trendelenburg, CF; Wolf, A1
Barr, SG; Harrison, JJ; Racz, WJ; Rafeiro, E1
Buè, MC; Ciriolo, MR; De Vito, P; Garaci, E; Incerpi, S; Lafavia, E; Palamara, AT; Rotilio, G1
Padgett, CM; Whorton, AR1
Schatten, G; Sutovsky, P1
Hannun, YA; Liu, B1
Ciriolo, MR; Civitareale, P; Coppola, S; Fanelli, C; Ghibelli, L; Rotilio, G; Scovassi, AI1
Ball, JG; Harmon, RC; Hong, SK; Meadows, MK; Rankin, GO; Valentovic, M1
Anwar, KN; Kefer, J; Malik, AB; Rahman, A1
Liu, AY; Manalo, DJ1
Chan, C; Goldkorn, T; Kawcak, T; Lavrentiadou, SN; Rasooly, R; Ravid, T; Tsaba, A; van der Vliet, A1
Cai, X; Huang, X; Zhou, Y1
Armstrong, JS; Birrell, GW; Hornung, B; Irish, JM; Knox, SJ; Lecane, P; Peehl, DM; Steinauer, KK1
Huang, F; Lin, Z; Liu, AY; Ma, ZF; Xu, K1
Andersen, JK; Chinta, SJ1
Han, YH; Kim, SH; Kim, SZ; Park, WH1
Coelho, IS; Dafre, AL; Franco, JL; Meotti, FC; Rocha, JB; Santos, AR1
Dafre, AL; Rodrigues, AL; Rosa, JM1
Chen, JG; Guan, XL; Wang, F; Wu, PF1
Brimacombe, KR; Dulcey, AE; Goldsborough, AS; Gottesman, MM; Griffiths, G; Hall, MD; Handley, MD; Kannan, P; Pluchino, KM1

Other Studies

23 other study(ies) available for dithiothreitol and buthionine sulfoximine

ArticleYear
Depletion of glutathione by L-buthionine sulfoximine does not promote inactivation of myo-inositol transport in cultured bovine lens epithelial cells.
    Current eye research, 1991, Volume: 10, Issue:4

    Topics: Animals; Antimetabolites; Biological Transport, Active; Buthionine Sulfoximine; Cattle; Cells, Cultured; Dithiothreitol; Epithelial Cells; Epithelium; Galactitol; Galactose; Glutamate-Cysteine Ligase; Glutathione; Inositol; Lens, Crystalline; Methionine Sulfoximine

1991
Participation of cellular thiol/disulphide groups in the uptake, degradation and bioactivity of insulin in primary cultures of rat hepatocytes.
    The Biochemical journal, 1985, Jan-15, Volume: 225, Issue:2

    Topics: Animals; Buthionine Sulfoximine; Cells, Cultured; Disulfides; Dithiothreitol; Glutathione; Insulin; Liver; Male; Methionine Sulfoximine; Rats; Rats, Inbred Strains; Sulfhydryl Compounds; Sulfhydryl Reagents

1985
Normal Ca2+ signalling in glutathione-depleted and dithiothreitol-treated HeLa cells.
    Pflugers Archiv : European journal of physiology, 1993, Volume: 423, Issue:5-6

    Topics: Antimetabolites; Buthionine Sulfoximine; Calcium; Cytosol; Dithiothreitol; Glutathione; HeLa Cells; Histamine; Histamine Release; Humans; Methionine Sulfoximine; Microscopy, Fluorescence; Signal Transduction; Terpenes; Thapsigargin

1993
Role of glutathione in cyclosporine A in vitro hepatotoxicity.
    Transplantation proceedings, 1994, Volume: 26, Issue:5

    Topics: Animals; Antimetabolites; Buthionine Sulfoximine; Cells, Cultured; Cyclosporine; Dithiothreitol; Dose-Response Relationship, Drug; Glutathione; Kinetics; L-Lactate Dehydrogenase; Lipid Peroxidation; Liver; Male; Methionine Sulfoximine; Rats; Rats, Wistar; Thiobarbituric Acid Reactive Substances

1994
Effects of N-acetylcysteine and dithiothreitol on glutathione and protein thiol replenishment during acetaminophen-induced toxicity in isolated mouse hepatocytes.
    Toxicology, 1994, Nov-11, Volume: 93, Issue:2-3

    Topics: Acetaminophen; Acetylcysteine; Animals; Buthionine Sulfoximine; Dithiothreitol; Glutathione; L-Lactate Dehydrogenase; Liver; Male; Methionine Sulfoximine; Mice; Sulfhydryl Compounds

1994
Loss of GSH, oxidative stress, and decrease of intracellular pH as sequential steps in viral infection.
    The Journal of biological chemistry, 1997, Jan-31, Volume: 272, Issue:5

    Topics: Adsorption; Animals; Buthionine Sulfoximine; Cell Line; Cysteine; Disulfides; Dithionitrobenzoic Acid; Dithiothreitol; Dogs; Glutathione; Glutathione Disulfide; Hydrogen-Ion Concentration; Kidney; L-Lactate Dehydrogenase; Methionine; Oxidative Stress; Respirovirus; Sodium-Hydrogen Exchangers; Ultraviolet Rays; Virus Replication

1997
Glutathione redox cycle regulates nitric oxide-mediated glyceraldehyde-3-phosphate dehydrogenase inhibition.
    The American journal of physiology, 1997, Volume: 272, Issue:1 Pt 1

    Topics: Animals; Buthionine Sulfoximine; Carmustine; Cattle; Cells, Cultured; Dithiothreitol; Endothelium, Vascular; Enzyme Inhibitors; Glutathione; Glutathione Reductase; Glyceraldehyde-3-Phosphate Dehydrogenases; Nitric Oxide; Oxidation-Reduction

1997
Depletion of glutathione during bovine oocyte maturation reversibly blocks the decondensation of the male pronucleus and pronuclear apposition during fertilization.
    Biology of reproduction, 1997, Volume: 56, Issue:6

    Topics: Animals; Buthionine Sulfoximine; Cattle; Cell Nucleus; Disulfides; Dithiothreitol; Female; Fertilization; Fertilization in Vitro; Glutathione; In Vitro Techniques; Male; Meiosis; Microscopy, Electron; Oocytes; Sperm Tail; Spermatozoa; Sulfhydryl Reagents

1997
Inhibition of the neutral magnesium-dependent sphingomyelinase by glutathione.
    The Journal of biological chemistry, 1997, Jun-27, Volume: 272, Issue:26

    Topics: Buthionine Sulfoximine; Dithiothreitol; Dose-Response Relationship, Drug; Glutathione; Humans; Magnesium; Sphingomyelin Phosphodiesterase; Tumor Cells, Cultured

1997
Glutathione depletion causes cytochrome c release even in the absence of cell commitment to apoptosis.
    FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 1999, Volume: 13, Issue:14

    Topics: Apoptosis; Buthionine Sulfoximine; Caspase 3; Caspases; Cell Survival; Cells, Cultured; Cytochrome c Group; Dithiothreitol; Enzyme Activation; Glutathione; Humans; Poly(ADP-ribose) Polymerases

1999
2-Amino-5-chlorophenol toxicity in renal cortical slices from Fischer 344 rats: effect of antioxidants and sulfhydryl agents.
    Toxicology and applied pharmacology, 1999, Nov-15, Volume: 161, Issue:1

    Topics: Animals; Antioxidants; Ascorbic Acid; Buthionine Sulfoximine; Chlorophenols; Deferoxamine; Dithiothreitol; Dose-Response Relationship, Drug; Free Radicals; Gluconeogenesis; Glutathione; In Vitro Techniques; Iron; Iron Chelating Agents; Kidney Cortex; Lipid Peroxidation; Male; Phenylenediamines; Pyruvic Acid; Rats; Rats, Inbred F344; Sulfhydryl Reagents

1999
Decreased oxidant buffering impairs NF-kappaB activation and ICAM-1 transcription in endothelial cells.
    Shock (Augusta, Ga.), 2001, Volume: 15, Issue:1

    Topics: Buthionine Sulfoximine; Cells, Cultured; Dithiothreitol; Endothelium, Vascular; Enzyme Inhibitors; Glutathione; Humans; Intercellular Adhesion Molecule-1; NF-kappa B; Oxidation-Reduction; Pulmonary Artery; Reactive Oxygen Species; RNA, Messenger; Transcription, Genetic; Tumor Necrosis Factor-alpha

2001
Resolution, detection, and characterization of redox conformers of human HSF1.
    The Journal of biological chemistry, 2001, Jun-29, Volume: 276, Issue:26

    Topics: Blotting, Western; Buthionine Sulfoximine; Diamide; Disulfides; Dithiothreitol; DNA-Binding Proteins; Ethylmaleimide; Glutathione; Heat Shock Transcription Factors; HeLa Cells; Hot Temperature; Humans; Nitric Oxide; Nitroso Compounds; Oxidation-Reduction; Protein Conformation; S-Nitrosoglutathione; Sulfhydryl Reagents; Transcription Factors

2001
Ceramide-mediated apoptosis in lung epithelial cells is regulated by glutathione.
    American journal of respiratory cell and molecular biology, 2001, Volume: 25, Issue:6

    Topics: Acetylcysteine; Amitrole; Annexin A5; Antioxidants; Apoptosis; Bronchi; Buthionine Sulfoximine; Catalase; Cells, Cultured; Ceramides; Diacylglycerol Kinase; Dithiothreitol; DNA Fragmentation; Dose-Response Relationship, Drug; Enzyme Inhibitors; Epithelial Cells; Flow Cytometry; Glutathione; Humans; Hydrogen Peroxide; In Situ Nick-End Labeling; Mercaptoethanol; Microscopy, Fluorescence; Oxidation-Reduction; Oxidative Stress; Pulmonary Alveoli; Reactive Oxygen Species; Trachea

2001
[Mechanisms of arsenic trioxide-induced apoptosis in myeloma cells].
    Zhonghua zhong liu za zhi [Chinese journal of oncology], 2001, Volume: 23, Issue:3

    Topics: Antineoplastic Agents; Apoptosis; Arsenic Trioxide; Arsenicals; Buthionine Sulfoximine; Cell Division; Dithiothreitol; Drug Interactions; Humans; Interferon-alpha; Multiple Myeloma; Oxides; Tretinoin; Tumor Cells, Cultured

2001
Role of glutathione depletion and reactive oxygen species generation in apoptotic signaling in a human B lymphoma cell line.
    Cell death and differentiation, 2002, Volume: 9, Issue:3

    Topics: Antimetabolites, Antineoplastic; Apoptosis; Buthionine Sulfoximine; Cell Cycle; Cytochrome c Group; Cytosol; Dithiothreitol; Glutathione; Humans; Lymphoma, B-Cell; Membrane Potentials; Mitochondria; NF-kappa B; Protein Transport; Reactive Oxygen Species; Signal Transduction; Transcription Factor RelA; Tumor Cells, Cultured; Tumor Suppressor Protein p53

2002
[Redox-dependent changes in structure and function of hHSF1].
    Sheng wu hua xue yu sheng wu wu li xue bao Acta biochimica et biophysica Sinica, 2003, Volume: 35, Issue:6

    Topics: Buthionine Sulfoximine; Diamide; Dithiothreitol; DNA-Binding Proteins; Dose-Response Relationship, Drug; Glutamate-Cysteine Ligase; Heat Shock Transcription Factors; Heat-Shock Proteins; HeLa Cells; Humans; Models, Molecular; Oxidation-Reduction; Protein Binding; Protein Conformation; Transcription Factors

2003
Reversible inhibition of mitochondrial complex I activity following chronic dopaminergic glutathione depletion in vitro: implications for Parkinson's disease.
    Free radical biology & medicine, 2006, Nov-01, Volume: 41, Issue:9

    Topics: Buthionine Sulfoximine; Cell Proliferation; Cells, Cultured; Dithiothreitol; Dopamine; Electron Transport Complex I; Glutamate-Cysteine Ligase; Glutathione; Humans; Mitochondria; Neurons; Nitric Oxide; Oxygen; Parkinson Disease; Peroxynitrous Acid; S-Nitrosothiols

2006
Carbonyl cyanide p-(trifluoromethoxy) phenylhydrazone (FCCP) as an O2(*-) generator induces apoptosis via the depletion of intracellular GSH contents in Calu-6 cells.
    Lung cancer (Amsterdam, Netherlands), 2009, Volume: 63, Issue:2

    Topics: Adenocarcinoma; Apoptosis; Buthionine Sulfoximine; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Line, Tumor; Dithiothreitol; Free Radical Scavengers; Glutathione; Humans; Lung Neoplasms; Superoxides

2009
Redox modulation at the peripheral site alters nociceptive transmission in vivo.
    Clinical and experimental pharmacology & physiology, 2009, Volume: 36, Issue:3

    Topics: Alkylating Agents; Analgesics; Animals; Azoles; Behavior, Animal; Buthionine Sulfoximine; Disease Models, Animal; Dithiothreitol; Dizocilpine Maleate; Enzyme Inhibitors; Excitatory Amino Acid Antagonists; Female; Glutamate-Cysteine Ligase; Glutamic Acid; Glutathione; Iodoacetates; Isoindoles; Mice; Organoselenium Compounds; Oxidation-Reduction; Pain; Receptors, N-Methyl-D-Aspartate; Reducing Agents; Signal Transduction; Sulfhydryl Compounds

2009
Antidepressant-like responses in the forced swimming test elicited by glutathione and redox modulation.
    Behavioural brain research, 2013, Sep-15, Volume: 253

    Topics: Animals; Antidepressive Agents; Antimetabolites; Antioxidants; Buthionine Sulfoximine; Depression; Dithionitrobenzoic Acid; Dithiothreitol; Female; gamma-Glutamyltransferase; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glutathione Transferase; Hindlimb Suspension; Injections, Intraventricular; Male; Mice; Motor Activity; Oxidation-Reduction; Swimming

2013
N-acetylcysteine facilitates extinction of cued fear memory in rats via reestablishing basolateral amygdala glutathione homeostasis.
    Acta pharmacologica Sinica, 2022, Volume: 43, Issue:2

    Topics: Acetylcysteine; Animals; Basolateral Nuclear Complex; Buthionine Sulfoximine; Conditioning, Classical; Cues; Dithiothreitol; Extinction, Psychological; Fear; Glutathione; Homeostasis; Male; Memory; Rats; Rats, Sprague-Dawley

2022
Collateral sensitivity of multidrug-resistant cells to the orphan drug tiopronin.
    Journal of medicinal chemistry, 2011, Jul-28, Volume: 54, Issue:14

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cell Line, Tumor; Doxorubicin; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; HEK293 Cells; Humans; Multidrug Resistance-Associated Proteins; Orphan Drug Production; Paclitaxel; RNA Stability; RNA, Messenger; Structure-Activity Relationship; Tiopronin

2011