disulfiram has been researched along with warfarin in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (50.00) | 18.7374 |
| 1990's | 1 (4.55) | 18.2507 |
| 2000's | 1 (4.55) | 29.6817 |
| 2010's | 9 (40.91) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Gangolli, SD; Hodgson, RA; Lake, BG; Longland, RC; Severn, BJ | 1 |
| O'Reilly, RA | 5 |
| Chin, JL | 1 |
| Rothstein, E | 2 |
| Griner, PF; Kleinman, PD | 1 |
| Marco, LA; Randels, PM | 1 |
| Baxter, PJ; Hankins, DC; Kharasch, ED; Thummel, KE | 1 |
| He, W; Jiang, T; Lan, Q; Liu, C; Nie, C; Wang, S; Xu, T; Zhang, C | 1 |
4 review(s) available for disulfiram and warfarin
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Vitamin K and the oral anticoagulant drugs.
Topics: Administration, Oral; Animals; Anti-Bacterial Agents; Anticoagulants; Aspirin; Barbiturates; Blood Coagulation; Blood Coagulation Factors; Blood Platelets; Chemical Phenomena; Chemistry; Cholestyramine Resin; Disulfiram; Diuretics; Drug Interactions; Ethanol; Female; Humans; Infant, Newborn; Male; Phenylbutazone; Prothrombin; Receptors, Drug; Vitamin K; Warfarin | 1976 |
The pharmacodynamics of the oral anticoagulant drugs.
Topics: Administration, Oral; Animals; Anticoagulants; Blood Coagulation; Blood Coagulation Factors; Blood Proteins; Clofibrate; Coumarins; Dicumarol; Disulfiram; Ethyl Biscoumacetate; Female; Heparin; Intestinal Absorption; Liver; Phenylbutazone; Protein Binding; Prothrombin; Prothrombin Time; Rabbits; Rats; Salicylates; Sulfonamides; Vitamin K; Vitamin K Deficiency; Warfarin | 1974 |
Hazards of anticoagulant treatment: other drugs, other diseases.
Topics: Administration, Oral; Animals; Anticoagulants; Barbiturates; Biological Transport; Blood Coagulation Factors; Clofibrate; Cycloheptanes; Depression, Chemical; Dicumarol; Disulfiram; Drug Interactions; Drug Synergism; Feces; Female; Half-Life; Humans; Hypoprothrombinemias; Infant, Newborn; Phenylbutazone; Pregnancy; Prothrombin Time; Rats; Receptors, Drug; Serum Albumin; Vitamin K Deficiency; Warfarin | 1973 |
1 trial(s) available for disulfiram and warfarin
| Article | Year |
|---|---|
Single-dose disulfiram does not inhibit CYP2A6 activity.
Topics: Administration, Oral; Adult; Antineoplastic Agents; Aryl Hydrocarbon Hydroxylases; Coumarins; Cross-Over Studies; Cytochrome P-450 CYP2A6; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Disulfiram; Double-Blind Method; Enzyme Inhibitors; Female; Humans; Male; Mixed Function Oxygenases; Umbelliferones | 1998 |
17 other study(ies) available for disulfiram and warfarin
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection | 2012 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
The effect of some foreign compounds on hepatic xenobiotic metabolism and on the urinary excretion of D-glucuronic acid metabolites in the rat.
Topics: Animals; Carbon Tetrachloride; Coumarins; Cytochrome P-450 Enzyme System; Disulfiram; Ethylmorphine-N-Demethylase; Glucuronates; Glucuronosyltransferase; Male; Microsomes, Liver; Organ Size; Oxidoreductases, N-Demethylating; Rats | 1977 |
Interaction of sodium warfarin and disulfiram (antabuse) in man.
Topics: Administration, Oral; Adult; Blood Coagulation; Disulfiram; Drug Synergism; Humans; Hypoprothrombinemias; Liver; Male; Prothrombin; Warfarin | 1973 |
Disulfiram and warfarin.
Topics: Blood Coagulation Disorders; Disulfiram; Drug Synergism; Humans; Warfarin | 1973 |
Warfarin effect enhanced by disulfiram (antabuse).
Topics: Alcoholism; Disulfiram; Drug Synergism; Humans; Male; Middle Aged; Warfarin | 1972 |
Studies of the epidemiology of anticoagulant-drug interactions.
Topics: Adult; Anticoagulants; Cholestyramine Resin; Dextrothyroxine; Disulfiram; Drug Antagonism; Drug Synergism; Humans; Phenethylamines; Phenylbutazone; Prothrombin Time; Warfarin | 1970 |
Warfarin effect enhanced by disulfiram.
Topics: Alcoholism; Aortic Valve Insufficiency; Disulfiram; Drug Synergism; Humans; Male; Middle Aged; Warfarin | 1968 |
Drug interactions in alcoholic patients.
Topics: Alcoholism; Anesthetics; Anti-Anxiety Agents; Anticonvulsants; Antidepressive Agents; Antihypertensive Agents; Antipsychotic Agents; Aspirin; Disulfiram; Drug Interactions; Ethanol; Ethylene Dibromide; Hemorrhage; Humans; Hypoglycemia; Hypotension; Methotrexate; Narcotics; Procarbazine; Sulfonylurea Compounds; Warfarin | 1981 |
Dynamic interaction between disulfiram and separated enantiomorphs of racemic warfarin.
Topics: Adult; Disulfiram; Drug Interactions; Humans; Male; Prothrombin Time; Stereoisomerism; Warfarin | 1981 |
Octa-arginine modified lipid emulsions as a potential ocular delivery system for disulfiram: A study of the corneal permeation, transcorneal mechanism and anti-cataract effect.
Topics: Animals; Cataract; Cornea; Coumarins; Disulfiram; Drug Delivery Systems; Emulsions; Fluorescent Dyes; Male; Ophthalmic Solutions; Particle Size; Peptides; Permeability; Rabbits; Rats; Rats, Sprague-Dawley; Sodium Selenite; Static Electricity | 2017 |