disulfiram and troleandomycin

disulfiram has been researched along with troleandomycin in 6 studies

Research

Studies (6)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (16.67)	18.2507
2000's	1 (16.67)	29.6817
2010's	4 (66.67)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Dansette, PM; Fontana, E; Poli, SM	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Ekins, S; Williams, AJ; Xu, JJ	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Kalhorn, TF; Kharasch, ED; Mitra, AK; Slattery, JT; Thummel, KE; Unadkat, JD	1
Kubickova, B; Martinkova, M; Stiborova, M	1

Reviews

1 review(s) available for disulfiram and troleandomycin

Article	Year
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity. Current drug metabolism, 2005, Volume: 6, Issue:5 Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic	2005

Trials

1 trial(s) available for disulfiram and troleandomycin

Article	Year
Metabolism of dapsone to its hydroxylamine by CYP2E1 in vitro and in vivo. Clinical pharmacology and therapeutics, 1995, Volume: 58, Issue:5 Topics: Adult; Alcohol Deterrents; Anti-Bacterial Agents; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dapsone; Disulfiram; Drug Interactions; Female; Humans; Hydroxylation; Leprostatic Agents; Male; Microsomes, Liver; Oxidoreductases, N-Demethylating; Troleandomycin	1995

Article

Year

Metabolism of dapsone to its hydroxylamine by CYP2E1 in vitro and in vivo.

Clinical pharmacology and therapeutics, 1995, Volume: 58, Issue:5

Topics: Adult; Alcohol Deterrents; Anti-Bacterial Agents; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Dapsone; Disulfiram; Drug Interactions; Female; Humans; Hydroxylation; Leprostatic Agents; Male; Microsomes, Liver; Oxidoreductases, N-Demethylating; Troleandomycin

1995

Other Studies

4 other study(ies) available for disulfiram and troleandomycin

Article	Year
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Effects of cytochrome P450 inhibitors on peroxidase activity. Neuro endocrinology letters, 2012, Volume: 33 Suppl 3 Topics: Benzoflavones; Cytochrome P-450 Enzyme Inhibitors; Disulfiram; Ditiocarb; Ellipticines; Enzyme Activation; Enzyme Inhibitors; Horseradish Peroxidase; Humans; Ketoconazole; Metyrapone; Piperonyl Butoxide; Proadifen; Quinidine; Structure-Activity Relationship; Substrate Specificity; Sulfaphenazole; Triazoles; Troleandomycin	2012