disulfiram and tretinoin

disulfiram has been researched along with tretinoin in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19903 (10.00)18.7374
1990's8 (26.67)18.2507
2000's9 (30.00)29.6817
2010's10 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ekins, S; Williams, AJ; Xu, JJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Bakmiwewa, SM; Ball, HJ; Fatokun, AA; Hunt, NH; Payne, RJ; Tran, A1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Dräger, UC; Lee, MO; McCaffery, P; Sladek, NE; Wagner, MA1
Napoli, JL1
Griffin, AC1
Dräger, UC; McCaffery, P1
Costaridis, P; Holder, N; Horton, C; Maden, M; Zeitlinger, J1
Horton, C; Maden, M; Stratford, T1
Kostakopoulou, K; Maden, M; Stratford, TH1
Corcoran, J; Maden, M1
Houghton, L; Neville, CM; Nikovits, W; Rosenthal, N; Shapiro, MD; Stockdale, FE; Wang, GF; Xavier-Neto, J1
Blythe, TJ; Grimes, ML; Kitson, KE1
Denisenko-Nehrbass, NI; Jarvis, E; Mello, CV; Nottebohm, F; Scharff, C1
Chandraratna, RA; del Rio-Tsonis, K; Rowland, T; Trombley, MT; Tsonis, PA1
Denisenko-Nehrbass, NI; Mello, CV1
Budman, DR; Calabro, A1
Pourquié, O; Vermot, J1
Chen, YG; Xie, F1
Engberg, N; Hansson, M; Kahn, M; Petersen, DR; Serup, P1
Abraham, DJ; Ahadome, SD; Calder, VL; Daniels, JT; Dart, JK; Norman, JT; Ponticos, M; Rayapureddi, S; Saban, DR; Saw, VP1

Reviews

2 review(s) available for disulfiram and tretinoin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Cancer chemoprevention.
    Journal of cancer research and clinical oncology, 1980, Volume: 98, Issue:1

    Topics: Animals; Antioxidants; Butylated Hydroxytoluene; Carcinogens; Disulfiram; Drug Therapy; Female; Humans; Inactivation, Metabolic; Male; Neoplasm Recurrence, Local; Neoplasms; Neoplasms, Experimental; Nutritional Requirements; Rats; Selenium; Tretinoin; Urinary Bladder Neoplasms; Vitamin A

1980

Other Studies

28 other study(ies) available for disulfiram and tretinoin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Identification of selective inhibitors of indoleamine 2,3-dioxygenase 2.
    Bioorganic & medicinal chemistry letters, 2012, Dec-15, Volume: 22, Issue:24

    Topics: Animals; Dose-Response Relationship, Drug; Enzyme Inhibitors; HEK293 Cells; Humans; Indoleamine-Pyrrole 2,3,-Dioxygenase; Mice; Models, Molecular; Molecular Structure; Structure-Activity Relationship; Substrate Specificity

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Asymmetrical retinoic acid synthesis in the dorsoventral axis of the retina.
    Development (Cambridge, England), 1992, Volume: 115, Issue:2

    Topics: Aldehyde Dehydrogenase; Animals; Colorimetry; Cytosol; Disulfiram; Enzyme Inhibitors; Isoelectric Focusing; Isoenzymes; Mice; Retina; Tretinoin

1992
Retinoic acid biosynthesis from retinol.
    Nutrition reviews, 1988, Volume: 46, Issue:1

    Topics: Alcohol Oxidoreductases; Aldehyde Oxidoreductases; Amsacrine; Animals; Cytochrome P450 Family 2; Disulfiram; NAD; Rats; Retinal Dehydrogenase; Tretinoin; Vitamin A

1988
Retinol metabolism in LLC-PK1 Cells. Characterization of retinoic acid synthesis by an established mammalian cell line.
    The Journal of biological chemistry, 1986, Oct-15, Volume: 261, Issue:29

    Topics: Animals; Cell Line; Disulfiram; Half-Life; Ketoconazole; Kidney; Kinetics; Swine; Tretinoin; Vitamin A

1986
High levels of a retinoic acid-generating dehydrogenase in the meso-telencephalic dopamine system.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Aug-02, Volume: 91, Issue:16

    Topics: Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Basal Ganglia; Corpus Striatum; Disulfiram; Dopamine; Hippocampus; Immunohistochemistry; Mice; Nucleus Accumbens; Olfactory Bulb; Telencephalon; Tissue Distribution; Tretinoin

1994
Endogenous retinoids in the zebrafish embryo and adult.
    Developmental dynamics : an official publication of the American Association of Anatomists, 1996, Volume: 205, Issue:1

    Topics: Alcohol Dehydrogenase; Aldehyde Oxidoreductases; Animals; Antimetabolites; Disulfiram; Enzyme Inhibitors; Fomepizole; Immunohistochemistry; Pyrazoles; Retinal Dehydrogenase; Retinaldehyde; Retinoids; Stereoisomerism; Tretinoin; Vitamin A; Zebrafish

1996
Retinoic acid is required for the initiation of outgrowth in the chick limb bud.
    Current biology : CB, 1996, Sep-01, Volume: 6, Issue:9

    Topics: Animals; Chick Embryo; Disulfiram; Extremities; Gene Expression Regulation, Developmental; Tretinoin

1996
Hoxb-8 has a role in establishing early anterior-posterior polarity in chick forelimb but not hindlimb.
    Development (Cambridge, England), 1997, Volume: 124, Issue:21

    Topics: Animals; Body Patterning; Chick Embryo; Disulfiram; Ectoderm; Forelimb; Gene Expression Regulation, Developmental; Hedgehog Proteins; Hindlimb; Homeodomain Proteins; Mesoderm; Proteins; Trans-Activators; Transcription, Genetic; Tretinoin

1997
Nerve growth factor acts via retinoic acid synthesis to stimulate neurite outgrowth.
    Nature neuroscience, 1999, Volume: 2, Issue:4

    Topics: Aldehyde Oxidoreductases; Animals; Disulfiram; DNA-Binding Proteins; Ganglia, Spinal; Mice; Nerve Growth Factors; Nerve Regeneration; Nerve Tissue Proteins; Neurites; Nuclear Receptor Subfamily 4, Group A, Member 1; Organ Culture Techniques; Oxidation-Reduction; PC12 Cells; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Receptors, Steroid; Recombinant Fusion Proteins; Retinal Dehydrogenase; Retinaldehyde; Transcription Factors; Tretinoin

1999
A retinoic acid-inducible transgenic marker of sino-atrial development in the mouse heart.
    Development (Cambridge, England), 1999, Volume: 126, Issue:12

    Topics: Alkaline Phosphatase; Animals; Disulfiram; Enzyme Inhibitors; Female; Gene Expression Regulation, Developmental; Genetic Markers; Heart; Heart Atria; Heart Defects, Congenital; Heart Ventricles; Humans; Mice; Mice, Transgenic; Pregnancy; Promoter Regions, Genetic; Response Elements; Signal Transduction; Transcription, Genetic; Transgenes; Tretinoin

1999
The role of retinoid metabolism by alcohol and aldehyde dehydrogenases in differentiation of cultured neuronal cells.
    Advances in experimental medicine and biology, 1999, Volume: 463

    Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Animals; Cell Differentiation; Disulfiram; Diterpenes; Ethanol; Humans; Isoenzymes; Neurons; Retinal Dehydrogenase; Retinaldehyde; Retinoids; Sheep; Tretinoin; Tumor Cells, Cultured

1999
Site-specific retinoic acid production in the brain of adult songbirds.
    Neuron, 2000, Volume: 27, Issue:2

    Topics: Aldehyde Dehydrogenase; Aldehyde Dehydrogenase 1 Family; Aldehyde Oxidoreductases; Animals; Autoradiography; Base Sequence; Brain; Cells, Cultured; Cloning, Molecular; Disulfiram; Drug Implants; Gene Expression; Isoenzymes; Male; Molecular Sequence Data; Nerve Tissue Proteins; Neurons; Organ Specificity; Retinal Dehydrogenase; Sequence Analysis, DNA; Sequence Homology, Amino Acid; Songbirds; Substrate Specificity; Tretinoin; Vocalization, Animal

2000
Role of retinoic acid in lens regeneration.
    Developmental dynamics : an official publication of the American Association of Anatomists, 2000, Volume: 219, Issue:4

    Topics: Animals; Antineoplastic Agents; Disulfiram; Enzyme Inhibitors; In Situ Hybridization; Lens, Crystalline; Morphogenesis; Notophthalmus viridescens; Receptors, Retinoic Acid; Regeneration; Tretinoin

2000
Molecular targets of disulfiram action on song maturation in zebra finches.
    Brain research. Molecular brain research, 2001, Mar-05, Volume: 87, Issue:2

    Topics: Aldehyde Dehydrogenase; Animals; Brain; Brain Chemistry; Conditioning, Psychological; Disulfiram; Enzyme Inhibitors; Male; Songbirds; Tretinoin; Vocalization, Animal

2001
In vitro search for synergy and antagonism: evaluation of docetaxel combinations in breast cancer cell lines.
    Breast cancer research and treatment, 2002, Volume: 74, Issue:1

    Topics: Antibiotics, Antineoplastic; Antineoplastic Agents; Antineoplastic Agents, Phytogenic; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Disulfiram; Docetaxel; Drug Interactions; Drug Screening Assays, Antitumor; Enzyme Inhibitors; Epirubicin; Female; Humans; Paclitaxel; Razoxane; Taxoids; Tretinoin; Tumor Cells, Cultured; Vinblastine; Vinorelbine

2002
Retinoic acid coordinates somitogenesis and left-right patterning in vertebrate embryos.
    Nature, 2005, May-12, Volume: 435, Issue:7039

    Topics: Aldehyde Oxidoreductases; Animals; Avian Proteins; Biomarkers; Body Patterning; Chick Embryo; Disulfiram; Embryo, Mammalian; Fibroblast Growth Factor 8; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Glycosyltransferases; Hedgehog Proteins; Mice; Signal Transduction; Somites; Trans-Activators; Tretinoin

2005
[Influence of disulfiram on the expression of transforming growth factor-beta2 in form-deprived eyes in chicks].
    Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences, 2008, Dec-18, Volume: 40, Issue:6

    Topics: Animals; Chickens; Disulfiram; Myopia; Random Allocation; Retina; RNA, Messenger; Sensory Deprivation; Transforming Growth Factor beta2; Tretinoin; Up-Regulation

2008
Retinoic acid synthesis promotes development of neural progenitors from mouse embryonic stem cells by suppressing endogenous, Wnt-dependent nodal signaling.
    Stem cells (Dayton, Ohio), 2010, Volume: 28, Issue:9

    Topics: Acyclic Monoterpenes; Animals; Cell Differentiation; Cells, Cultured; Disulfiram; Embryonic Stem Cells; Enzyme Inhibitors; Fibroblast Growth Factors; Gene Expression Regulation, Developmental; Genes, Reporter; Mesoderm; Mice; Monoterpenes; Naphthalenes; Neural Plate; Neurons; Nodal Protein; Receptors, Retinoic Acid; Signal Transduction; Time Factors; Transfection; Tretinoin; Vitamin A; Wnt Proteins

2010
Aldehyde dehydrogenase inhibition blocks mucosal fibrosis in human and mouse ocular scarring.
    JCI insight, 2016, 08-04, Volume: 1, Issue:12

    Topics: Adult; Aged; Aged, 80 and over; Aldehyde Dehydrogenase; Animals; Cells, Cultured; Cicatrix; Conjunctiva; Disulfiram; Female; Fibroblasts; Fibrosis; Humans; Male; Mice; Mice, Inbred C57BL; Middle Aged; Mucous Membrane; Pemphigoid, Benign Mucous Membrane; Tretinoin

2016