disulfiram and thioguanine anhydrous

disulfiram has been researched along with thioguanine anhydrous in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (18.18)29.6817
2010's4 (36.36)24.3611
2020's5 (45.45)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Anderson, L; Bassi, ÊJ; Cardoso, SH; da Silva Santos-Júnior, PF; da Silva-Júnior, EF; de Andrade Brandão, J; Silva, LR; Xavier de Araújo-Júnior, J1
Hu, Y; Jadhav, P; Tan, B; Tan, H; Wang, J1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Chen, WY; Cheng, SC; Chu, HF; Kuan, Y; Lin, HC; Lin, TH; Pan, HC; Sun, CY1
An, X; Chu, M; Dai, X; Li, Q; Li, Z; Yu, H; Zhang, D1

Reviews

3 review(s) available for disulfiram and thioguanine anhydrous

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Druggable targets from coronaviruses for designing new antiviral drugs.
    Bioorganic & medicinal chemistry, 2020, 11-15, Volume: 28, Issue:22

    Topics: Animals; Antiviral Agents; Drug Design; Humans; Middle East Respiratory Syndrome Coronavirus; Pandemics; SARS-CoV-2

2020
Progress and Challenges in Targeting the SARS-CoV-2 Papain-like Protease.
    Journal of medicinal chemistry, 2022, 06-09, Volume: 65, Issue:11

    Topics: Antiviral Agents; Coronavirus Papain-Like Proteases; COVID-19 Drug Treatment; Humans; Pandemics; Protease Inhibitors; SARS-CoV-2

2022

Other Studies

8 other study(ies) available for disulfiram and thioguanine anhydrous

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Disulfiram and 6-Thioguanine synergistically inhibit the enzymatic activities of USP2 and USP21.
    International journal of biological macromolecules, 2021, Apr-15, Volume: 176

    Topics: Disulfiram; Drug Synergism; Enzyme Inhibitors; Humans; Thioguanine; Ubiquitin Thiolesterase

2021
Combination of the 6-thioguanine and disulfiram/Cu synergistically inhibits proliferation of triple-negative breast cancer cells by enhancing DNA damage and disrupting DNA damage checkpoint.
    Biochimica et biophysica acta. Molecular cell research, 2022, Volume: 1869, Issue:2

    Topics: Acetaldehyde Dehydrogenase Inhibitors; Animals; Antimetabolites, Antineoplastic; Apoptosis; Cell Cycle Checkpoints; Cell Proliferation; Copper; Disulfiram; DNA Damage; Drug Therapy, Combination; Female; Humans; Mice; Mice, Inbred BALB C; Mice, Nude; NF-kappa B; Phosphorylation; Thioguanine; Triple Negative Breast Neoplasms; Tumor Cells, Cultured; Xenograft Model Antitumor Assays

2022