Compounds > disulfiram

disulfiram and s-methyl diethylthiocarbamate

disulfiram has been researched along with s-methyl diethylthiocarbamate in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's5 (83.33)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Kitson, TM1
Fauq, AH; Lipsky, JJ; Mays, DC; Naylor, S; Nelson, AN; Shriver, ZH; Veverka, KA1
Faiman, MD; Madan, A; Nagendra, SN1
Faiman, MD; Madan, A; Parkinson, A2
Hochreiter, J; Lapham, J; Ma, Q; McCance-Katz, EF; Morse, GD1

Other Studies

6 other study(ies) available for disulfiram and s-methyl diethylthiocarbamate

ArticleYear
Effect of some thiocarbamate compounds on aldehyde dehydrogenase and implications for the disulfiram ethanol reaction.
    The Biochemical journal, 1991, Aug-15, Volume: 278 ( Pt 1)

    Topics: Aldehyde Dehydrogenase; Animals; Carbamates; Disulfides; Disulfiram; Ditiocarb; Kinetics; Liver; Sheep; Thiocarbamates

1991
S-methyl N,N-diethylthiocarbamate sulfone, a potential metabolite of disulfiram and potent inhibitor of low Km mitochondrial aldehyde dehydrogenase.
    Biochemical pharmacology, 1995, Mar-01, Volume: 49, Issue:5

    Topics: Aldehyde Dehydrogenase; Animals; Disulfiram; Dithiothreitol; Enzyme Reactivators; Glutathione; Kinetics; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Sulfones; Thiocarbamates

1995
S-methyl N,N-diethylthiolcarbamate sulfone, an in vitro and in vivo inhibitor of rat liver mitochondrial low Km aldehyde dehydrogenase.
    Biochemical pharmacology, 1994, Apr-20, Volume: 47, Issue:8

    Topics: Aldehyde Dehydrogenase; Animals; Disulfiram; Ditiocarb; Male; Mitochondria, Liver; Oxidation-Reduction; Rats; Thiocarbamates

1994
Role of flavin-dependent monooxygenases and cytochrome P450 enzymes in the sulfoxidation of S-methyl N,N-diethylthiolcarbamate.
    Biochemical pharmacology, 1993, Dec-14, Volume: 46, Issue:12

    Topics: Animals; Antibodies; Biotransformation; Cytochrome P-450 Enzyme System; Disulfiram; Ditiocarb; Male; Microsomes, Liver; Oxygenases; Rats; Rats, Sprague-Dawley; Sulfoxides; Thiocarbamates

1993
Identification of the human and rat P450 enzymes responsible for the sulfoxidation of S-methyl N,N-diethylthiolcarbamate (DETC-ME). The terminal step in the bioactivation of disulfiram.
    Drug metabolism and disposition: the biological fate of chemicals, 1995, Volume: 23, Issue:10

    Topics: Animals; Aryl Hydrocarbon Hydroxylases; Biotransformation; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Disulfiram; Ditiocarb; Humans; Male; Microsomes, Liver; Rabbits; Rats; Thiocarbamates

1995
Disulfiram metabolite S-methyl-N,N-diethylthiocarbamate quantitation in human plasma with reverse phase ultra performance liquid chromatography and mass spectrometry.
    Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 2012, May-15, Volume: 897

    Topics: Chromatography, High Pressure Liquid; Chromatography, Reverse-Phase; Disulfiram; Drug Stability; Humans; Mass Spectrometry; Reproducibility of Results; Thiocarbamates

2012