disulfiram has been researched along with methyldopa in 50 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 39 (78.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (6.00) | 29.6817 |
| 2010's | 8 (16.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Campillo, NE; Guerra, A; Páez, JA | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A | 1 |
| Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Duvoisin, RC; Marsden, CD | 2 |
| Korkhov, VV; Poskalenko, AN; Veshilova, TP | 1 |
| Khlebarova, M; Kiriakov, A; Panova, I; Staneva-stoicheva, D | 2 |
| Anisimov, VN | 1 |
| Lotti, VJ; Stone, CA; Torchiana, ML | 1 |
| Day, MD; Roach, AG; Whiting, RL | 2 |
| Bergmann, F; Chaimovitz, M; Pasternak, V; Ramu, A | 1 |
| Gey, KF; Haefely, W; Hürlmann, A; Thoenen, H | 1 |
| Afrikanov, II; Vedernikov, YP | 1 |
| Porter, CC; Torchiana, ML | 1 |
| Henning, M; Rubenson, A | 1 |
| Jackson, DM | 1 |
| Aihara, H; Kasai, A; Sakai, T | 1 |
| Presthus, J | 1 |
| Barreca, T; Foppiani, E; Giordano, G; Marugo, M; Minuto, F | 2 |
| Gjessing, LR; Takahashi, S | 1 |
| Djahanguiri, B; Hemmati, M; Rezvani, A | 1 |
| Calesnick, B; Irvin, JD; Mathews, GJ; Osterholm, JL | 1 |
| Cohen, Y; Jacquot, C; Rapin, J; Wepierre, J | 1 |
| Haefely, W | 1 |
| Giardina, WJ; Sabelli, HC | 1 |
| Prabhu, S; Sharma, VN; Singh, V | 1 |
| Koe, BK; Weissman, A | 1 |
| Brown, RM; Lal, H | 1 |
| Borud, O; Gjessing, LR; Nishimura, T | 1 |
| Gérardy, J | 1 |
| Goldberg, ME; Salama, AI | 1 |
| Borud, O; Gjessing, LR | 1 |
| Gulati, OD; Parikh, HM; Ringe, SY; Sherlekar, ML | 1 |
| Kariya, T; Kobayashi, K; Kobayashi, T; Nagao, Y; Takahashi, R; Takamizawa, M; Toru, M; Tsuchiya, K | 1 |
| Gjessing, LR | 1 |
| Weber, LJ | 1 |
| Bhagat, B; Jackson, CJ; Kopin, IJ; Musacchio, JM | 1 |
| Bhagat, B; Dhalla, NS; Gray, L | 1 |
| Garibova, TL; Voronina, TA | 1 |
3 review(s) available for disulfiram and methyldopa
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
[Other trials with drug therapy in parkinsonism].
Topics: 5-Hydroxytryptophan; Amitriptyline; Animals; Dihydroxyphenylalanine; Disulfiram; Drug Evaluation; Drug Therapy, Combination; Humans; Imipramine; Methyldopa; Monoamine Oxidase Inhibitors; Parkinson Disease; Picolinic Acids; Rats; Serine; Time Factors; Tryptophan; Tyrosine | 1973 |
[Drugs with effect on the adrenergic nerve fiber].
Topics: Aminocaproates; Amitriptyline; Amphetamine; Bretylium Compounds; Chlorpromazine; Disulfiram; Dopamine; Ephedrine; Guanethidine; Humans; Imipramine; Mental Disorders; Metaraminol; Methyldopa; Methyltyrosines; Monoamine Oxidase Inhibitors; Neurons; Norepinephrine; Octopamine; Prenylamine; Reserpine; Sympathetic Nervous System; Sympathomimetics; Tetrabenazine; Tyramine; Vascular Diseases | 1968 |
47 other study(ies) available for disulfiram and methyldopa
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship | 2008 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Prediction of drug intestinal absorption by new linear and non-linear QSPR.
Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics | 2011 |
FDA-approved drug labeling for the study of drug-induced liver injury.
Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration | 2011 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Alpha-methyldopamine as a dopaminergic agonist.
Topics: Animals; Bis(4-Methyl-1-Homopiperazinylthiocarbonyl)disulfide; Blood Pressure; Carboxy-Lyases; Depression, Chemical; Disulfiram; Dopamine; Dose-Response Relationship, Drug; Drug Interactions; Locomotion; Methyldopa; Mice; Phenoxybenzamine; Pimozide; Receptors, Drug; Reserpine; Time Factors | 1975 |
[Combined use of steroid preparations and antiadrenergic substances for contraceptive purposes].
Topics: Animals; Contraceptives, Oral; Disulfiram; Drug Evaluation; Female; Megestrol; Mestranol; Methyldopa; Phenoxybenzamine; Propranolol; Rats | 1975 |
[The effect of prolonged treatment of hypertensive rats with antihypertensive drugs of various actions on the arterial tension and noradrenaline level in the myocardium, brain and aortal].
Topics: Animals; Antihypertensive Agents; Aorta; Brain Chemistry; Disulfiram; Furosemide; Guanethidine; Hypertension; Methyldopa; Myocardium; Norepinephrine; Rats; Reserpine | 1975 |
[Pharmacologic study of adrenergic mechanisms of compensatory hypertrophy of the ovary].
Topics: Animals; Castration; Chlorpromazine; Diethylstilbestrol; Disulfiram; Female; Follicle Stimulating Hormone; Levodopa; Methyldopa; Ovary; Phenytoin; Rats; Sympathetic Nervous System | 1975 |
The anticonvulsant effect of carbonic anhydrase inhibitors in mice--a noradrenergic mechanism of action.
Topics: Acetazolamide; Amino Acids; Animals; Anticonvulsants; Carbonic Anhydrase Inhibitors; Carboxy-Lyases; Dichlorphenamide; Dihydroxyphenylalanine; Disulfiram; Dopamine beta-Hydroxylase; Dose-Response Relationship, Drug; Electroshock; Female; Hydrazines; Methazolamide; Methyldopa; Mice; Monoamine Oxidase Inhibitors; Picolinic Acids; Reserpine | 1973 |
The mechanism of the antihypertensive action of -methyldopa in hypertensive rats.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Blood Pressure; Desoxycorticosterone; Disulfiram; Hypertension; Male; Methyldopa; Monophenol Monooxygenase; Rats; Thiocarbamates; Time Factors | 1973 |
Compulsive gnawing in rats after implantation of drugs into the ventral thalamus. A contribution to the mechanism of morphine action.
Topics: Amphetamine; Animals; Apomorphine; Brain; Chlorpromazine; Compulsive Behavior; Corpus Striatum; Disulfiram; Dose-Response Relationship, Drug; Drug Synergism; Fenclonine; Haloperidol; Humans; Meperidine; Methadone; Methyldopa; Methyltyrosines; Morphine; Nalorphine; Phenoxybenzamine; Phentolamine; Pimozide; Rats; Thalamus | 1974 |
Liberation of alpha-methyldopamine as a "false" sympathetic transmitter after pretreatment of cats with alpha-methyldopa and disulfiram.
Topics: Animals; Blood Pressure; Catecholamines; Cats; Chromatography, Paper; Disulfiram; Dopamine; Epinephrine; Heart; In Vitro Techniques; Methyldopa; Mixed Function Oxygenases; Myocardium; Neurotransmitter Agents; Nictitating Membrane; Norepinephrine; Normetanephrine; Perfusion; Spleen; Sympathetic Nervous System; Synaptic Transmission | 1967 |
On the role of a central adrenergic mechanism in morphine analgesic action.
Topics: Amphetamine; Animals; Brain; Cocaine; Disulfiram; Drug Synergism; Female; Iproniazid; Methyldopa; Morphine; Norepinephrine; Pyrogallol; Rats; Reserpine; Tryptophan | 1969 |
4,4,6-trimethyl-3,4-dihydropyrimidine-2-thiol, an effective inhibitor of dopamine-beta-hydroxylation in vivo.
Topics: Acetaldehyde; Amino Alcohols; Animals; Benzyl Compounds; Blood Pressure; Brain Chemistry; Carbon Isotopes; Cattle; Dihydroxyphenylalanine; Disulfiram; Dopamine; Ethanol; Ethylamines; Female; Heart; Hydrazines; Iodine; Male; Metaraminol; Methyldopa; Methyltyrosines; Mice; Mixed Function Oxygenases; Monoamine Oxidase Inhibitors; Myocardium; Norepinephrine; Normetanephrine; Propylthiouracil; Pyrimidines; Rats; Reserpine; Stereoisomerism; Sulfhydryl Compounds; Thyroid Gland; Tyramine | 1971 |
Evidence for a centrally mediated hypotensive effect of L-dopa in the rat.
Topics: Animals; Blood Pressure; Central Nervous System; Depression, Chemical; Dihydroxyphenylalanine; Disulfides; Disulfiram; Dopamine beta-Hydroxylase; Hydrazines; Imidazoles; Male; Methyldopa; Rats; Rats, Inbred Strains | 1970 |
The effect of -phenethylamine upon spontaneous motor activity in mice: a dual effect on locomotor activity.
Topics: Animals; Desipramine; Dibenzocycloheptenes; Disulfiram; Equipment and Supplies; Injections, Intraperitoneal; Male; Methyldopa; Methyltyrosines; Methysergide; Mice; Motor Activity; Phenethylamines; Reserpine; Time Factors | 1972 |
The effect of dopamine on peripheral vasculature of the rat.
Topics: Animals; Blood Pressure; Blood Vessels; Cocaine; Constriction; Depression, Chemical; Disulfiram; Dopamine; Dopamine Antagonists; Drug Synergism; Ephedrine; Ergotamine; Haloperidol; Hindlimb; Kidney; Male; Methyldopa; Morphine; Norepinephrine; Perfusion; Propranolol; Rats; Reserpine; Stimulation, Chemical; Tyramine | 1972 |
[Sleep-wakefulness rhythm of the somatotropin secretion in the man under the influence of alpha-methyldopa and disulfiram].
Topics: Adult; Circadian Rhythm; Disulfiram; Female; Growth Hormone; Humans; Hypothalamus; Male; Methyldopa; Middle Aged; Pituitary Hormone-Releasing Hormones; Sleep; Wakefulness | 1973 |
Studies of periodic catatonia. IV. Longitudinal study of catecholamine metabolism, with and without drugs.
Topics: Body Temperature; Catatonia; Catecholamines; Chromatography, Thin Layer; Disulfiram; Dopamine; Epinephrine; Humans; Lithium; Male; Methyldopa; Middle Aged; Monoamine Oxidase Inhibitors; Norepinephrine; Periodicity; Pulse; Reserpine | 1972 |
Prevention of aspirin-induced gastric ulceration in rats by alpha-methyldopa and disulfiram.
Topics: Animals; Aspirin; Disulfiram; Dose-Response Relationship, Drug; Female; Male; Methyldopa; Peptic Ulcer; Rats | 1973 |
Chapter 29. Anti-norepinephrine therapy against traumatic hemorrhagic necrosis of the spinal cord: preliminary report.
Topics: Animals; Bretylium Compounds; Cats; Dihydroxyphenylalanine; Disease Models, Animal; Disulfiram; Guanethidine; Hemorrhage; Hydroxydopamines; Methyldopa; Necrosis; Norepinephrine; Phenoxybenzamine; Reserpine; Spinal Cord; Spinal Cord Injuries; Sympatholytics | 1973 |
[Behavior of the somatotropin peak during sleep under the influence of alpha-methyldopa and disulfiram].
Topics: Adult; Disulfiram; Female; Growth Hormone; Humans; Male; Methyldopa; Middle Aged; Pituitary Gland; Sleep | 1973 |
[The effect of prolonged treatment hypertensive rats with antihypertensive agents with different mechanisms of action on blood pressure and noradrenaline concentration in the myocardium, brain and aorta].
Topics: Animals; Antihypertensive Agents; Aorta; Blood Pressure; Brain Chemistry; Clonidine; Disulfiram; Furosemide; Guanethidine; Hypertension; Male; Methyldopa; Myocardium; Norepinephrine; Rats; Reserpine | 1973 |
Reversal of reserpine-induced bradykinesia by alpha-methyldopa--new light on its modus operandi.
Topics: Animals; Carbidopa; Chlorpromazine; Dihydroxyphenylalanine; Disease Models, Animal; Disulfiram; Dose-Response Relationship, Drug; Drug Synergism; Methyldopa; Mice; Movement Disorders; Parkinson Disease; Phenoxybenzamine; Pimozide; Reserpine | 1974 |
[Relationship between the antihypertensive activity of methyldopa and the appearance of its metabolites in the heart and brain of the hypertensive rat].
Topics: Animals; Antihypertensive Agents; Aromatic Amino Acid Decarboxylase Inhibitors; Benserazide; Biotransformation; Blood Pressure; Brain; Disulfides; Disulfiram; Dopamine; Dopamine beta-Hydroxylase; Hydrazines; Hypertension; Imidazoles; Male; Methane; Methyldopa; Myocardium; Norepinephrine; Rats; Sympatholytics; Time Factors; Tritium | 1974 |
Tranquilizing and electrophysiological effects of nicotine.
Topics: Animals; Arousal; Cerebral Cortex; Depression, Chemical; Disulfiram; Drug Synergism; Electric Stimulation; Electrodes, Implanted; Electroencephalography; Evoked Potentials; Exploratory Behavior; Injections, Intravenous; Male; Methyldopa; Methyltyrosines; Mice; Motor Cortex; Nicotine; Pargyline; Photic Stimulation; Rabbits; Sleep | 1972 |
The effect of drugs on stress-induced changes of myocardial glycogen and blood glucose concentration in rats.
Topics: Adrenal Glands; Animals; Blood Glucose; Dactinomycin; Disulfiram; Female; Glycogen; Immobilization; Male; Methyldopa; Methyltyrosines; Myocardium; Rats; Stress, Physiological | 1972 |
The mode of action of -methyldopa.
Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Disulfiram; Hydrazines; Hypertension; Methyldopa; Rats; Thiocarbamates | 1972 |
m-Fluorotyrosine convulsions and mortality: relationship to catecholamine and citrate metabolism.
Topics: 5-Hydroxytryptophan; Amphetamine; Animals; Anticonvulsants; Atropine; Azoles; Brain; Chlordiazepoxide; Chlorpromazine; Citrates; Dihydroxyphenylalanine; Disulfiram; Drug Antagonism; Drug Synergism; Kidney; Lysergic Acid Diethylamide; Male; Methyldopa; Mice; Morphine; Nialamide; Norepinephrine; Pargyline; Phenobarbital; Phenytoin; Reserpine; Seizures; Serotonin; Strychnine; Tetrabenazine; Trimethadione; Tyrosine; Urea | 1967 |
A possible relationship between catecholamines and acute toxicity of desipramine.
Topics: 5-Hydroxytryptophan; Animals; Catecholamines; Chlorpromazine; Desipramine; Dihydroxyphenylalanine; Disulfiram; Male; Methyldopa; Mice; Mortality; Phenylalanine; Reserpine | 1968 |
Studies on urinary phenolic compounds in man. I. Excretion of p-hydroxy-mandelic acid by man.
Topics: Amino Acid Metabolism, Inborn Errors; Chromatography; Disulfiram; Humans; In Vitro Techniques; Mandelic Acids; Methyldopa; Neuroblastoma; Octopamine; Phenelzine; Phenylketonurias; Thyroxine; Triiodothyronine; Tyrosine; Urine | 1965 |
[Inhibitors of the enzymes of noradrenaline synthesi].
Topics: Animals; Carboxy-Lyases; Cats; Depression, Chemical; Disulfiram; Guinea Pigs; Humans; Methyldopa; Mixed Function Oxygenases; Norepinephrine | 1969 |
Effect of alpha-methyltyrosine on stress-induced changes in seizure susceptibility.
Topics: Animals; Brain Chemistry; Catecholamines; Chlorpromazine; Disulfiram; Male; Methyldopa; Methyltyrosines; Mice; Monoamine Oxidase Inhibitors; Phenylalanine; Reserpine; Seizures; Stress, Physiological; Tetrabenazine; Time Factors; Tyrosine | 1970 |
Excretion of vanylglycol in human urine under dietary control, and during treatment with antibiotics, disulfiram, a monoamineoxidase inhibitor, alphamethyldopa and reserpine.
Topics: Adult; Anti-Bacterial Agents; Benzoates; Chromatography, Paper; Chromatography, Thin Layer; Diet; Disulfiram; Glycols; Humans; Male; Methyldopa; Monoamine Oxidase Inhibitors; Norepinephrine; Phenols; Reserpine; Sucrose | 1970 |
An investigation of alpha-methyl amino-acids and their derivatives on isolated tissue preparations.
Topics: Amino Acids; Animals; Cocaine; Disulfiram; Dopamine; Ear, External; Heart; Ileum; In Vitro Techniques; Metaraminol; Methyldopa; Methyltyrosines; Normetanephrine; Perfusion; Rabbits; Rats; Reserpine; Sodium; Tyramine | 1970 |
Catecholamine metabolism of manic-depressive illness.
Topics: Antidepressive Agents; Bipolar Disorder; Calcium; Catecholamines; Creatinine; Disulfiram; Dopamine; Epinephrine; Humans; Hydroxyindoleacetic Acid; Imipramine; Male; Methyldopa; Middle Aged; Norepinephrine; Phenylacetates; Psychiatric Status Rating Scales; Vanilmandelic Acid | 1968 |
Studies on urinary phenolic compounds in man. II. Phenolic-acids and -amines during a load of alpha-methyl-dopa and disulfiram in periodic catatonia.
Topics: Adult; Aldehydes; Catatonia; Catecholamines; Chromatography; Disulfiram; Electrophoresis; Humans; Male; Methyldopa; Norepinephrine; Oxidoreductases; Phenols; Urine | 1965 |
Drug interactions between disulfiram and alpha-methyldopa and related agents in reserpine-pretreated rats.
Topics: Animals; Blood Pressure; Carbamates; Catecholamines; Dihydroxyphenylalanine; Disulfiram; Dopamine; Methyldopa; Norepinephrine; Rats; Reserpine; Tyramine | 1966 |
The effect of disulfiram on the restoration of the response to tyramine by dopamine and alpha-methyl-dopa in the reserpine-treated cat.
Topics: Animals; Blood Pressure; Cats; Disulfiram; Dopa Decarboxylase; Dopamine; Enzymes; Methyldopa; Nictitating Membrane; Norepinephrine; Reserpine; Tyramine | 1966 |
Restoration of the response of the isolated atria of guinea-pigs to tyramine and possible significance of beta-hydroxylation.
Topics: Amines; Animals; Dihydroxyphenylalanine; Disulfiram; Dopamine; Guinea Pigs; Heart Atria; Heart Conduction System; In Vitro Techniques; Male; Methyldopa; Myocardium; Norepinephrine; Rats; Reserpine; Sinoatrial Node; Tritium; Tyramine | 1966 |
[Role of GABA-ergic and dopaminergic mechanisms in the withdrawal syndrome after discontinuation of long-term phenazepam administration].
Topics: 5-Hydroxytryptophan; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Brain; Dihydroxyphenylalanine; Disulfiram; Dopamine; gamma-Aminobutyric Acid; Humans; Male; Methyldopa; Rats; Semicarbazides; Substance Withdrawal Syndrome; Valproic Acid | 1980 |