disulfiram and gemcitabine

disulfiram has been researched along with gemcitabine in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's4 (57.14)24.3611
2020's2 (28.57)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Easwaran, M; Manickam, M; Pillaiyar, T; Wendt, LL1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Armesilla, AL; Brown, J; Darling, JL; Goessl, E; Guo, X; Pandey, S; Wang, W; Xu, B1
Armesilla, AL; Bian, X; Brown, S; Channathodiyil, P; Darling, JL; Goktug, T; Guichet, PO; Hugnot, JP; Kannappan, V; Liu, P; Wang, W1
Chung, C; Kim, H; Kim, SK; Kim, T; Kim, TS; Koh, GY; Lee, DH; Lim, DS1

Reviews

2 review(s) available for disulfiram and gemcitabine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The recent outbreaks of human coronaviruses: A medicinal chemistry perspective.
    Medicinal research reviews, 2021, Volume: 41, Issue:1

    Topics: Antiviral Agents; Chemistry, Pharmaceutical; COVID-19; Disease Outbreaks; Drug Repositioning; Humans; Virus Internalization

2021

Other Studies

5 other study(ies) available for disulfiram and gemcitabine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Disulfiram/copper complex inhibiting NFkappaB activity and potentiating cytotoxic effect of gemcitabine on colon and breast cancer cell lines.
    Cancer letters, 2010, Apr-01, Volume: 290, Issue:1

    Topics: Antineoplastic Agents; Blotting, Western; Breast Neoplasms; Cell Line, Tumor; Colonic Neoplasms; Copper; Deoxycytidine; Disulfiram; Drug Resistance, Neoplasm; Drug Synergism; Electrophoretic Mobility Shift Assay; Female; Fluorouracil; Gemcitabine; Humans; NF-kappa B; Ribonucleoside Diphosphate Reductase; Thymidylate Synthase; Tumor Suppressor Proteins

2010
Cytotoxic effect of disulfiram/copper on human glioblastoma cell lines and ALDH-positive cancer-stem-like cells.
    British journal of cancer, 2012, Oct-23, Volume: 107, Issue:9

    Topics: Aldehyde Dehydrogenase; Apoptosis; Brain Neoplasms; Cell Line, Tumor; Copper; Cytotoxicity, Immunologic; Deoxycytidine; Disulfiram; Drug Synergism; Gemcitabine; Glioblastoma; Humans; MAP Kinase Kinase 4; MAP Kinase Signaling System; Neoplastic Stem Cells; NF-kappa B; p38 Mitogen-Activated Protein Kinases; Reactive Oxygen Species

2012
Reversing the intractable nature of pancreatic cancer by selectively targeting ALDH-high, therapy-resistant cancer cells.
    PloS one, 2013, Volume: 8, Issue:10

    Topics: Aldehyde Dehydrogenase; Analysis of Variance; Animals; Blotting, Western; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Deoxycytidine; Disulfiram; Drug Delivery Systems; Drug Resistance, Neoplasm; Flow Cytometry; Gemcitabine; Humans; Immunohistochemistry; Mice; Neoplastic Stem Cells; Pancreatic Neoplasms; Real-Time Polymerase Chain Reaction

2013