disulfiram has been researched along with fomepizole in 22 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (22.73) | 18.7374 |
| 1990's | 6 (27.27) | 18.2507 |
| 2000's | 4 (18.18) | 29.6817 |
| 2010's | 6 (27.27) | 24.3611 |
| 2020's | 1 (4.55) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Crossley, IR; Davis, M; Eddleston, AL; Neuberger, J; Williams, R | 1 |
| Kaplita, PV; Smith, RP | 1 |
| Israel, Y; Kera, Y; Lindros, KO; Penttilä, KE; Speisky, H | 1 |
| Lindros, KO; Pikkarainen, P; Salaspuro, M; Stowell, A | 1 |
| Pösö, AR; Pösö, H | 1 |
| Baraona, E; Flisiak, R; Li, J; Lieber, CS | 1 |
| Heng, JK; Palmer, TN; Xu, D | 1 |
| Riddle, MM; Smialowicz, RJ; Williams, WC | 1 |
| Albano, E; Aragno, M; Biasi, F; Chiarpotto, E; Danni, O; Dianzani, MU; Poli, G; Scavazza, A; Tamagno, E | 1 |
| Costaridis, P; Holder, N; Horton, C; Maden, M; Zeitlinger, J | 1 |
| Azzalis, LA; Boveris, A; Giavarotti, L; Junqueira, VB; Lissi, EA; Llesuy, S; Porta, EA; Simon, KA; Videla, LA | 1 |
| Frosini, M; Fusi, F; Pessina, F; Sgaragli, GP; Tipton, KF; Valoti, M | 1 |
| Chen, HH; Chiu, TH; Shih, CL | 1 |
| Hazai, E; Monostory, K; Vereczkey, L | 1 |
| Cheung, C; Hotchkiss, SA; Pease, CK | 1 |
| Chen, YT; Hung, DZ; Liao, JW | 1 |
| Monte, AA; Sande, M; Thompson, D | 1 |
| Beike, J; Bender, K; Jübner, M; Käferstein, H; Lenz, D; Rothschild, MA; Wintermeyer, A | 1 |
| Bakke, SA; Laursen, SB | 1 |
| Alhaider, IA; Emeka, PM; Ibrahim, HIM; Mohamed, ME; Morsy, MA | 1 |
1 review(s) available for disulfiram and fomepizole
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
21 other study(ies) available for disulfiram and fomepizole
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Ethanol metabolism in the generation of new antigenic determinants on liver cells.
Topics: Alcohol Oxidoreductases; Aldehyde Dehydrogenase; Animals; Cytotoxicity Tests, Immunologic; Disulfiram; Epitopes; Ethanol; Female; Fomepizole; Liver; Pyrazoles; Rabbits | 1986 |
Pathways for the bioactivation of aliphatic nitriles to free cyanide in mice.
Topics: Alcohol Dehydrogenase; Alcohol Oxidoreductases; Animals; Biotransformation; Cyanides; Dimethyl Sulfoxide; Disulfiram; Fomepizole; Lethal Dose 50; Male; Mice; Microsomes, Liver; Mixed Function Oxygenases; Nitriles; Prostaglandin-Endoperoxide Synthases; Pyrazoles; Salicylates; Substrate Specificity | 1986 |
Depletion of hepatic glutathione by ethanol occurs independently of ethanol metabolism.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Cyanamide; Disulfiram; Ethanol; Female; Fomepizole; Glutathione; In Vitro Techniques; Liver; Male; Pyrazoles; Rats; Rats, Inbred Strains | 1988 |
The disulfiram (Antabuse)-Alcohol reaction in male alcoholics: its efficient management by 4-methylpyrazole.
Topics: Adult; Alcohol Oxidoreductases; Alcoholism; Cyanamide; Disulfiram; Fomepizole; Humans; Male; Pyrazoles | 1981 |
Inhibition of ornithine decarboxylase in regenerating rat liver by acute ethanol treatment.
Topics: Acetaldehyde; Alanine Transaminase; Animals; Carboxy-Lyases; Disulfiram; Ethanol; Female; Fomepizole; Hepatectomy; Kidney; Liver; Liver Regeneration; Ornithine Decarboxylase Inhibitors; Pyrazoles; Rats | 1980 |
Effects of ethanol on prostanoid production by liver fat-storing cells.
Topics: 6-Ketoprostaglandin F1 alpha; Acetaldehyde; Alcohol Dehydrogenase; Animals; Cytosol; Dinoprostone; Disulfiram; Epoprostenol; Ethanol; Fomepizole; Isoenzymes; Lipid Metabolism; Liver; Male; Pyrazoles; Rats; Rats, Sprague-Dawley | 1993 |
The mechanism(s) of the alcohol-induced impairment in glycogen synthesis in oxidative skeletal muscles.
Topics: Animals; Blood Glucose; Disulfiram; Ethanol; Fomepizole; Glycogen; Male; Muscles; Oxidation-Reduction; Pyrazoles; Rats; Rats, Wistar | 1993 |
Methoxyacetaldehyde, an intermediate metabolite of 2-methoxyethanol, is immunosuppressive in the rat.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Animals; Antibody Formation; Cyanamide; Disulfiram; Ethylene Glycols; Fomepizole; Immune Tolerance; Lipopolysaccharides; Male; Pyrazoles; Rats; Rats, Inbred F344; Solvents | 1993 |
In vivo potentiation of 1,2-dibromoethane hepatotoxicity by ethanol through inactivation of glutathione-s-transferase.
Topics: Alcohol Dehydrogenase; Animals; Cytochrome P-450 CYP2E1; Cytochrome P-450 Enzyme System; Disulfiram; Ethanol; Ethylene Dibromide; Fomepizole; Glutathione; Glutathione Transferase; L-Iditol 2-Dehydrogenase; Liver; Male; Malondialdehyde; Oxidoreductases, N-Demethylating; Pyrazoles; Rats; Rats, Wistar | 1996 |
Endogenous retinoids in the zebrafish embryo and adult.
Topics: Alcohol Dehydrogenase; Aldehyde Oxidoreductases; Animals; Antimetabolites; Disulfiram; Enzyme Inhibitors; Fomepizole; Immunohistochemistry; Pyrazoles; Retinal Dehydrogenase; Retinaldehyde; Retinoids; Stereoisomerism; Tretinoin; Vitamin A; Zebrafish | 1996 |
In situ rat brain and liver spontaneous chemiluminescence after acute ethanol intake.
Topics: Alcohol Deterrents; Animals; Antioxidants; Brain; Disulfiram; Dose-Response Relationship, Drug; Ethanol; Fomepizole; Glutathione; Injections, Intraperitoneal; Lipid Peroxidation; Liver; Luminescent Measurements; Male; Oxidative Stress; Pyrazoles; Rats; Rats, Wistar; Time Factors | 1997 |
Cytochrome P450-dependent N-dealkylation of L-deprenyl in C57BL mouse liver microsomes: effects of in vivo pretreatment with ethanol, phenobarbital, beta-naphthoflavone and L-deprenyl.
Topics: Animals; beta-Naphthoflavone; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Disulfiram; Enzyme Induction; Enzyme Inhibitors; Ethanol; Fomepizole; In Vitro Techniques; Isoenzymes; Ketoconazole; Mice; Mice, Inbred C57BL; Microsomes, Liver; Monoamine Oxidase Inhibitors; NADH, NADPH Oxidoreductases; NADPH-Ferrihemoprotein Reductase; Phenobarbital; Pyrazoles; Selegiline | 2000 |
Acute exposure to trichloroethylene differentially alters the susceptibility to chemoconvulsants in mice.
Topics: Animals; Anticonvulsants; Antidotes; Convulsants; Disulfiram; Dose-Response Relationship, Drug; Drug Interactions; Enzyme Inhibitors; Fomepizole; Male; Mice; Pentylenetetrazole; Pyrazoles; Reflex; Seizures; Solvents; Trichloroethylene | 2001 |
Reduction of toxic metabolite formation of acetaminophen.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Benzoquinones; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Disulfiram; Ditiocarb; Enzyme Inhibitors; Fomepizole; Humans; Imines; Microsomes, Liver; Pyrazoles | 2002 |
Cinnamic compound metabolism in human skin and the role metabolism may play in determining relative sensitisation potency.
Topics: Acrolein; Adult; Alcohol Dehydrogenase; Aldehyde-Lyases; Chromatography, High Pressure Liquid; Cytosol; Dermatitis, Contact; Disulfiram; Enzyme Inhibitors; Female; Fomepizole; Hot Temperature; Humans; Inactivation, Metabolic; Propanols; Pyrazoles; Skin; Subcellular Fractions | 2003 |
Protective effects of fomepizole on 2-chloroethanol toxicity.
Topics: Acetaldehyde; Acetylcysteine; Alcohol Dehydrogenase; Aldehyde Dehydrogenase; Animals; Antidotes; Antioxidants; Disulfiram; Drug Synergism; Enzyme Inhibitors; Ethylene Chlorohydrin; Fomepizole; Glutathione; Kidney; Lethal Dose 50; Liver; Male; Pyrazoles; Rats; Rats, Sprague-Dawley; Solvents | 2010 |
Fomepizole for severe disulfiram-ethanol reactions.
Topics: Acetaldehyde; Alcohol Dehydrogenase; Antidotes; Disulfiram; Drug Interactions; Ethanol; Female; Flushing; Fomepizole; Humans; Hypotension; Middle Aged; Pyrazoles; Tachycardia; Young Adult | 2012 |
Inhibition of 1,4-butanediol metabolism in human liver in vitro.
Topics: Adult; Aged; Antidotes; Butylene Glycols; Cimetidine; Disulfiram; Drug Interactions; Ethanol; Female; Fomepizole; Gas Chromatography-Mass Spectrometry; Humans; Hydroxybutyrates; In Vitro Techniques; Liver; Male; Middle Aged; Pyrazoles | 2011 |
[Treatment with disulfiram can be dangerous].
Topics: Aged; Alcohol Deterrents; Antidotes; Bronchial Spasm; Disulfiram; Drug Interactions; Ethanol; Female; Fomepizole; Humans; Hypotension; Pyrazoles | 2011 |
Subchronic administration of mitoxantrone and the influence of enzyme inhibitors on its induced cardiotoxicity in mice: role of NRF-2/CYP2E1.
Topics: Animals; Antineoplastic Agents; Cardiotoxicity; Caspase 3; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Disulfiram; Female; Fomepizole; Male; Mice, Inbred BALB C; Mitoxantrone; Myocardium; NF-E2-Related Factor 2; Troponin I | 2021 |