disulfiram has been researched along with ebselen in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (16.67) | 29.6817 |
| 2010's | 5 (27.78) | 24.3611 |
| 2020's | 10 (55.56) | 2.80 |
| Authors | Studies |
|---|---|
| Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J | 1 |
| Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Hagerman, TK; Karver, CE; Kawarski, M | 1 |
| Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
| Al Temimi, AHK; Lenstra, DC; Mecinović, J | 1 |
| Bai, F; Deng, Y; Du, X; Duan, Y; Guddat, LW; Jiang, H; Jiang, R; Jin, Z; Li, X; Liu, F; Liu, H; Liu, M; Liu, X; Peng, C; Qin, C; Rao, Z; Shi, Z; Wang, L; Xiao, G; Xu, W; Xu, Y; Yang, H; Yang, K; Yang, X; You, T; Yu, J; Zhang, B; Zhang, L; Zhao, Y | 1 |
| Alonso, C; Barrado-Gil, L; Campillo, NE; Cuesta-Geijo, MÁ; Gil, C; Ginex, T; Maestro, I; Martinez, A; Nozal, V; Ramírez, D; Urquiza, J | 1 |
| Easwaran, M; Manickam, M; Pillaiyar, T; Wendt, LL | 1 |
| Anderson, L; Bassi, ÊJ; Cardoso, SH; da Silva Santos-Júnior, PF; da Silva-Júnior, EF; de Andrade Brandão, J; Silva, LR; Xavier de Araújo-Júnior, J | 1 |
| Amin, SA; Banerjee, S; Gayen, S; Ghosh, K; Jha, T | 1 |
| Chen, J; Gao, K; Huang, F; Tepe, JJ; Wang, R; Wei, GW | 1 |
| Baev, D; Belenkaya, S; Chirkova, V; Dalinger, A; Kalinin, M; Khvostov, A; Krut'ko, D; Maksyutov, R; Medved'ko, A; Salakhutdinov, N; Shanshin, D; Sharlaeva, E; Shcherbakov, D; Tolstikova, T; Vatsadze, S; Volosnikova, E; Yarovaya, O | 1 |
| Cao, H; Chen, H; Han, X; Huang, Y; Liu, J; Peng, C; Rao, L; Ren, Y; Sheng, C; Su, C; Tu, J; Wan, C; Wan, J; Wen, W | 1 |
| Hu, Y; Jadhav, P; Tan, B; Tan, H; Wang, J | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Mecinović, J; Rose, NR; Schofield, CJ; Seden, PT; Sekirnik, R; Thalhammer, A | 1 |
| Igarashi, M; Kabir, MHB; Kato, K; Maenaka, K; Mitsuhashi, S; Ohsaka, F; Okada, T; Otsuguro, S; Sarwono, AEY; Shigetomi, K; Ubukata, M | 1 |
5 review(s) available for disulfiram and ebselen
| Article | Year |
|---|---|
COVID-19: Drug Targets and Potential Treatments.
Topics: Amino Acid Sequence; Animals; Antiviral Agents; COVID-19 Drug Treatment; Drug Repositioning; Enzyme Inhibitors; Humans; Immunity, Innate; SARS-CoV-2 | 2020 |
The recent outbreaks of human coronaviruses: A medicinal chemistry perspective.
Topics: Antiviral Agents; Chemistry, Pharmaceutical; COVID-19; Disease Outbreaks; Drug Repositioning; Humans; Virus Internalization | 2021 |
Druggable targets from coronaviruses for designing new antiviral drugs.
Topics: Animals; Antiviral Agents; Drug Design; Humans; Middle East Respiratory Syndrome Coronavirus; Pandemics; SARS-CoV-2 | 2020 |
Protease targeted COVID-19 drug discovery and its challenges: Insight into viral main protease (Mpro) and papain-like protease (PLpro) inhibitors.
Topics: Antiviral Agents; Catalytic Domain; Coronavirus 3C Proteases; Cysteine Proteinase Inhibitors; Drug Discovery; Drug Evaluation, Preclinical; Molecular Docking Simulation; Molecular Structure; Protein Binding; Quantitative Structure-Activity Relationship; SARS-CoV-2 | 2021 |
Progress and Challenges in Targeting the SARS-CoV-2 Papain-like Protease.
Topics: Antiviral Agents; Coronavirus Papain-Like Proteases; COVID-19 Drug Treatment; Humans; Pandemics; Protease Inhibitors; SARS-CoV-2 | 2022 |
13 other study(ies) available for disulfiram and ebselen
| Article | Year |
|---|---|
Chemical genetics reveals a complex functional ground state of neural stem cells.
Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells | 2007 |
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection | 2009 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Lazaroids U83836E and U74389G are potent, time-dependent inhibitors of caspase-1.
Topics: Antioxidants; Caspase 1; Caspase Inhibitors; Drug Discovery; Humans; Small Molecule Libraries | 2015 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
Inhibition of histone lysine methyltransferases G9a and GLP by ejection of structural Zn(II).
Topics: Dose-Response Relationship, Drug; Enzyme Inhibitors; Histocompatibility Antigens; Histone-Lysine N-Methyltransferase; Humans; Molecular Structure; Small Molecule Libraries; Structure-Activity Relationship; Zinc Fingers | 2018 |
Structure of M
Topics: Antiviral Agents; Betacoronavirus; Cells, Cultured; Coronavirus 3C Proteases; Coronavirus Infections; COVID-19; Cysteine Endopeptidases; Drug Design; Drug Discovery; Drug Evaluation, Preclinical; Humans; Models, Molecular; Pandemics; Pneumonia, Viral; Protease Inhibitors; Protein Structure, Tertiary; SARS-CoV-2; Viral Nonstructural Proteins | 2020 |
Perspectives on SARS-CoV-2 Main Protease Inhibitors.
Topics: Antiviral Agents; Coronavirus 3C Proteases; Humans; Protease Inhibitors | 2021 |
Design and Evaluation of Bispidine-Based SARS-CoV-2 Main Protease Inhibitors.
Topics: | 2022 |
Structure-Guided Discovery of the Novel Covalent Allosteric Site and Covalent Inhibitors of Fructose-1,6-Bisphosphate Aldolase to Overcome the Azole Resistance of
Topics: Allosteric Site; Antifungal Agents; Azoles; Biofilms; Candida albicans; Candida parapsilosis; Drug Resistance, Fungal; Enzyme Inhibitors; Fructose-Bisphosphate Aldolase; Fungal Proteins; Microbial Sensitivity Tests; Molecular Structure; Protein Binding; Structure-Activity Relationship | 2022 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Inhibition of the histone lysine demethylase JMJD2A by ejection of structural Zn(II).
Topics: Azoles; Binding Sites; Catalytic Domain; Crystallography, X-Ray; Disulfiram; Isoindoles; Jumonji Domain-Containing Histone Demethylases; Organoselenium Compounds; Selenium; Spectrometry, Mass, Electrospray Ionization; Zinc | 2009 |
Repurposing existing drugs: identification of irreversible IMPDH inhibitors by high-throughput screening.
Topics: Animals; Azoles; Cryptosporidium parvum; Disulfiram; Drug Discovery; Drug Repositioning; Enzyme Inhibitors; High-Throughput Screening Assays; Humans; IMP Dehydrogenase; Isoindoles; Kinetics; Mice; Mice, SCID; Organoselenium Compounds; Proof of Concept Study; Propylene Glycols; Small Molecule Libraries | 2019 |