disulfiram has been researched along with cocaine in 43 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (30.23) | 18.7374 |
| 1990's | 6 (13.95) | 18.2507 |
| 2000's | 7 (16.28) | 29.6817 |
| 2010's | 15 (34.88) | 24.3611 |
| 2020's | 2 (4.65) | 2.80 |
| Authors | Studies |
|---|---|
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Bhagat, B; Gilliam, J | 1 |
| Maj, J; Przegaliński, E; Wielosz, M | 1 |
| Afrikanov, II; Vedernikov, YP | 1 |
| Vedernikov, YP | 1 |
| Aihara, H; Kasai, A; Sakai, T | 1 |
| Aihara, H; Ozawa, H; Sasajima, M; Tanaka, I | 1 |
| Gajda, L; Grabowska, M; Maj, J | 1 |
| Lee, FL; Trendelenburg, U; Weiner, N | 1 |
| Gulati, OD; Parikh, HM; Ringe, SY; Sherlekar, ML | 1 |
| Bhargava, KP; Kar, K; Parmar, S | 1 |
| Koppanyi, T; Maengwyn-Davies, GD | 1 |
| Langer, SZ; Trendelenburg, U; Tsai, TH | 1 |
| Greenbaum, DM; McEnrue, J; Olson, E | 1 |
| Hameedi, FA; Jatlow, PI; Kosten, TR; McCance-Katz, EF; McMahon, TJ; Price, LH; Rosen, MI; Woods, SW | 1 |
| Houri, D | 1 |
| Budney, AJ; Higgins, ST | 1 |
| Bickel, WK; Budney, AJ; Foerg, F; Higgins, ST; Hughes, JR | 1 |
| Jatlow, P; Kosten, TR; McCance-Katz, EF | 1 |
| Ball, SA; Carroll, KM; McCance, E; Nich, C; Rounsavile, BJ | 1 |
| During, MJ; Haile, CN; Jatlow, PI; Kosten, TA; Kosten, TR | 1 |
| Kosten, TR; Sofuoglu, M | 1 |
| Baker, JR; Jatlow, P; McCance-Katz, EF | 1 |
| Antonilli, L; Cioce, AM; Giudici, FD; Grassi, MC; Nencini, P | 1 |
| Liles, LC; Schank, JR; Weinshenker, D | 1 |
| Gaval-Cruz, M; Javors, MA; Liles, LC; Schroeder, JP; Weinshenker, D | 1 |
| Diehl, A; Kiefer, F; Mutschler, J | 1 |
| Cooper, DA; Edwards, GL; Freeman, KG; Gaval-Cruz, M; Holmes, PV; Iuvone, PM; Lyle, MA; Ogbonmwan, YE; Pozdeyev, N; Schank, JR; Schroeder, JP; Weinshenker, D | 1 |
| Cargile, C; Carroll, KM; Chopra, MP; Cubells, JF; Feldman, Z; Gonsai, K; Gonzalez-Haddad, G; Kosten, TR; Mancino, MJ; Oliveto, A; Poling, J; Pruzinsky, R; Sofuoglu, M | 1 |
| Anderson, A; De La Garza, R; Elkashef, A; Kahn, R; Mojsiak, J; Murff, WL; Newton, TF; Rivera, O; Roache, JD; Wallace, CL | 1 |
| Cadeddu, R; Devoto, P; Flore, G; Gessa, GL; Saba, P | 1 |
| Hamon, SC; Harding, MJ; Huang, W; Kosten, TR; Nielsen, DA | 1 |
| De La Garza, R; Haile, CN; Kosten, TR; Mahoney, JJ; Newton, TF; Nielsen, DA | 1 |
| Gaval-Cruz, M; Iuvone, PM; Liles, LC; Weinshenker, D | 1 |
| Almeida, LJ; Baldaçara, L; Diniz, TA; Fernandes, CC; Milhomem, JJ; Parreira, BL | 1 |
| DePoy, LM; Manvich, DF; Weinshenker, D | 1 |
| Babuscio, TA; Carroll, KM; Kiluk, BD; Nich, C | 1 |
| Aubin, HJ; Lahmek, P; Pham, H; Skinner, MD | 1 |
| Cooper, DA; Howell, LL; Kimmel, HL; Manvich, DF; Schmidt, KT; Weinshenker, D | 1 |
| Antinori, S; Devoto, P; Fattore, L; Fratta, W; Frau, R; Gessa, GL; Saba, P | 1 |
| Bergman, J; de Moura, FB; Kohut, SJ | 1 |
| Fitzmaurice, GM; Lipsitz, SR; Weiss, RD | 1 |
| Hamon, SC; Harding, MJ; Kosten, TR; Nielsen, DA; Nielsen, EM; Patriquin, M; Spellicy, CJ; Thomas, PS; Ye, A | 1 |
3 review(s) available for disulfiram and cocaine
| Article | Year |
|---|---|
Treatment of cocaine dependence through the principles of behavior analysis and behavioral pharmacology.
Topics: Behavior Therapy; Cocaine; Counseling; Disulfiram; Humans; Substance-Related Disorders | 1993 |
Emerging pharmacological strategies in the fight against cocaine addiction.
Topics: Adrenergic beta-Antagonists; Animals; Benzhydryl Compounds; Brain; Central Nervous System Stimulants; Cocaine; Cocaine-Related Disorders; Disulfiram; Dopamine; Dopamine Agents; Dopamine beta-Hydroxylase; Drug Evaluation, Preclinical; Enzyme Inhibitors; GABA Agonists; GABA Plasma Membrane Transport Proteins; GABA Uptake Inhibitors; gamma-Aminobutyric Acid; Humans; Modafinil; Nipecotic Acids; Propranolol; Randomized Controlled Trials as Topic; Tiagabine; Vaccines | 2006 |
Disulfiram efficacy in the treatment of alcohol dependence: a meta-analysis.
Topics: Adolescent; Adult; Aged; Alcohol Deterrents; Alcoholism; Case-Control Studies; Cocaine; Disulfiram; Endpoint Determination; Female; Humans; Male; Middle Aged; Randomized Controlled Trials as Topic; Treatment Outcome | 2014 |
12 trial(s) available for disulfiram and cocaine
| Article | Year |
|---|---|
Behavioral, physiological, and pharmacological interaction of cocaine and disulfiram in humans.
Topics: Adult; Affect; Alcoholism; Arousal; Brain; Cocaine; Disulfiram; Double-Blind Method; Drug Interactions; Euphoria; Female; Humans; Male; Neurologic Examination; Paranoid Behavior; Substance-Related Disorders | 1995 |
Chronic disulfiram treatment effects on intranasal cocaine administration: initial results.
Topics: Administration, Intranasal; Adult; Alcohol Deterrents; Blood Pressure; Cocaine; Disulfiram; Double-Blind Method; Female; Heart Rate; Humans; Male; Substance-Related Disorders | 1998 |
Treatment of cocaine and alcohol dependence with psychotherapy and disulfiram.
Topics: Adult; Alcohol Deterrents; Alcoholism; Cocaine; Cognitive Behavioral Therapy; Combined Modality Therapy; Disulfiram; Female; Humans; Male; Substance-Related Disorders | 1998 |
Disulfiram effects on responses to intravenous cocaine administration.
Topics: Adult; Alcohol Deterrents; Cocaine; Cocaine-Related Disorders; Disulfiram; Double-Blind Method; Female; Humans; Male; Metabolic Clearance Rate | 2007 |
Short-term efficacy of Disulfiram or Naltrexone in reducing positive urinalysis for both cocaine and cocaethylene in cocaine abusers: a pilot study.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Combined Modality Therapy; Disulfiram; Humans; Naltrexone; Narcotic Antagonists; Patient Compliance; Pilot Projects; Time Factors; Treatment Outcome | 2007 |
Randomized, double blind, placebo-controlled trial of disulfiram for the treatment of cocaine dependence in methadone-stabilized patients.
Topics: Adult; Alcohol Drinking; Cocaine; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Disulfiram; Dose-Response Relationship, Drug; Female; Humans; Male; Methadone; Opiate Substitution Treatment; Opioid-Related Disorders; Self Report | 2011 |
A double-blind, placebo-controlled assessment of the safety of potential interactions between intravenous cocaine, ethanol, and oral disulfiram.
Topics: Adult; Alcohol Deterrents; Blood Pressure; Central Nervous System Depressants; Cocaine; Cocaine-Related Disorders; Disulfiram; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Drug Interactions; Electrocardiography; Ethanol; Female; Heart Rate; Humans; Male; Middle Aged; Placebos; Psychiatric Status Rating Scales; Substance-Related Disorders; Treatment Outcome; Young Adult | 2011 |
Modifying the role of serotonergic 5-HTTLPR and TPH2 variants on disulfiram treatment of cocaine addiction: a preliminary study.
Topics: Adult; Alleles; Cocaine; Cocaine-Related Disorders; Comorbidity; Disulfiram; Female; Genetic Carrier Screening; Genetic Variation; Genotype; Heroin Dependence; Humans; Male; Methadone; Middle Aged; Serotonin; Serotonin Plasma Membrane Transport Proteins; Tryptophan Hydroxylase | 2012 |
The impact of disulfiram treatment on the reinforcing effects of cocaine: a randomized clinical trial.
Topics: Adult; Choice Behavior; Cocaine; Cocaine-Related Disorders; Cross-Over Studies; Disulfiram; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heart Rate; Humans; Male; Treatment Outcome | 2012 |
Could disulfiram be a new treatment for crack cocaine dependence?: a pilot study.
Topics: Adolescent; Adult; Cocaine-Related Disorders; Crack Cocaine; Disulfiram; Humans; Male; Medication Adherence; Pilot Projects; Reproducibility of Results; Treatment Outcome; Young Adult | 2013 |
Smokers versus snorters: do treatment outcomes differ according to route of cocaine administration?
Topics: Administration, Inhalation; Administration, Intranasal; Adult; Alcoholism; Cocaine; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Comorbidity; Disulfiram; Female; Humans; Male; Smoking; Treatment Outcome | 2013 |
The OPRD1 rs678849 variant influences outcome of disulfiram treatment for cocaine dependency in methadone-maintained patients.
Topics: Adult; Alleles; Cocaine; Cocaine-Related Disorders; Disulfiram; Female; Genotype; Humans; Male; Methadone; Middle Aged; Opioid-Related Disorders; Receptors, Opioid, delta; Treatment Outcome | 2021 |
28 other study(ies) available for disulfiram and cocaine
| Article | Year |
|---|---|
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Effect of various procedures on the repletion of cardiac catecholamine stores after tyramine.
Topics: Adrenal Medulla; Animals; Bretylium Compounds; Cocaine; Disulfiram; Enzymes; Hydrazines; Imipramine; In Vitro Techniques; Monoamine Oxidase Inhibitors; Myocardium; Norepinephrine; Radiometry; Rats; Tritium; Tyramine | 1965 |
Disulfiram and the drug-induced effects on motility.
Topics: Amphetamine; Animals; Brain Chemistry; Cocaine; Dihydroxyphenylalanine; Disulfiram; Methyltyrosines; Motor Activity; Nialamide; Norepinephrine; Pargyline; Rats; Reserpine | 1968 |
On the role of a central adrenergic mechanism in morphine analgesic action.
Topics: Amphetamine; Animals; Brain; Cocaine; Disulfiram; Drug Synergism; Female; Iproniazid; Methyldopa; Morphine; Norepinephrine; Pyrogallol; Rats; Reserpine; Tryptophan | 1969 |
The role of brain catecholamines in morphine analgesic action in morphine tolerant rats.
Topics: Amphetamine; Analgesics; Animals; Brain; Catecholamines; Cocaine; Disulfiram; Drug Synergism; Drug Tolerance; Female; Iproniazid; Morphine; Norepinephrine; Pyrogallol; Rats; Reserpine; Tryptophan | 1970 |
The effect of dopamine on peripheral vasculature of the rat.
Topics: Animals; Blood Pressure; Blood Vessels; Cocaine; Constriction; Depression, Chemical; Disulfiram; Dopamine; Dopamine Antagonists; Drug Synergism; Ephedrine; Ergotamine; Haloperidol; Hindlimb; Kidney; Male; Methyldopa; Morphine; Norepinephrine; Perfusion; Propranolol; Rats; Reserpine; Stimulation, Chemical; Tyramine | 1972 |
[Effects of dopamine on the isolated left atrium of the rat].
Topics: Animals; Cocaine; Disulfiram; Dopamine; Dopamine Antagonists; Drug Synergism; Heart Atria; Hydroxydopamines; In Vitro Techniques; Iproniazid; Lithium; Male; Norepinephrine; Propranolol; Rats; Reserpine; Tyramine | 1974 |
Effect of apomorphine on motility in rats.
Topics: Animals; Apomorphine; Behavior, Animal; Benzoates; Benzyl Compounds; Brain Chemistry; Catecholamines; Cocaine; Desipramine; Dihydroxyphenylalanine; Disulfiram; Drug Antagonism; Esters; Fluorine; Haloperidol; Hydrazines; Male; Motor Activity; Nialamide; Nortriptyline; Phenoxybenzamine; Rats; Rats, Inbred Strains; Reserpine; Serine; Spiro Compounds; Stimulation, Chemical; Thiocarbamates; Tranquilizing Agents; Tyrosine | 1972 |
The uptake of tyramine and formation of octopamine in normal and tachyphylactic rat atria.
Topics: Animals; Cocaine; Disulfiram; Heart; Heart Atria; Myocardium; Norepinephrine; Octopamine; Rats; Tachyphylaxis; Tritium; Tyramine | 1967 |
An investigation of alpha-methyl amino-acids and their derivatives on isolated tissue preparations.
Topics: Amino Acids; Animals; Cocaine; Disulfiram; Dopamine; Ear, External; Heart; Ileum; In Vitro Techniques; Metaraminol; Methyldopa; Methyltyrosines; Normetanephrine; Perfusion; Rabbits; Rats; Reserpine; Sodium; Tyramine | 1970 |
Mechanism of action of dopamine and other precursors of noradrenaline on the guinea-pig isolated hypogastric nerve vas deferens preparation.
Topics: Animals; Cocaine; Dihydroxyphenylalanine; Disulfiram; Dopamine; Guinea Pigs; Hypogastric Plexus; Male; Norepinephrine; Phenoxybenzamine; Reserpine; Tyramine; Tyrosine; Vas Deferens | 1968 |
Cocaine tachyphylaxis and effects on indirectly-acting sympathomimetic drugs in the rabbit aortic strip and in splenic tissue.
Topics: Amphetamine; Animals; Aorta; Cocaine; Dextroamphetamine; Disulfiram; Enzymes; In Vitro Techniques; Iproniazid; Methyltyrosines; Nialamide; Norepinephrine; Pargyline; Phenylephrine; Rabbits; Spleen; Tachyphylaxis; Tranylcypromine; Tyramine; Tyrosine | 1966 |
Effects of dopamine and alpha-methyl-dopamine on smooth muscle and on the cardiac pacemaker.
Topics: Animals; Cats; Cocaine; Denervation; Disulfiram; Dopamine; Ganglia, Autonomic; Guinea Pigs; Heart Atria; Heart Conduction System; Injections, Intravenous; Muscle, Smooth; Nictitating Membrane; Norepinephrine; Reserpine; Sensory Receptor Cells; Statistics as Topic; Sympathomimetics | 1967 |
Clinical aspects of drug intoxication: alcohols and miscellaneous agents.
Topics: 1-Propanol; Alcoholic Intoxication; Cocaine; Disulfiram; Ethanol; Ethylene Glycols; Humans; Lithium; Methanol; Phencyclidine; Substance-Related Disorders | 1983 |
[Cocaine toxicity, enhancing effects in grouped mice and mechanism on behavioral characteristics].
Topics: Animals; Behavior, Animal; Biogenic Amines; Carbamazepine; Cocaine; Disulfiram; Dose-Response Relationship, Drug; Drug Interactions; Lethal Dose 50; Male; Methamphetamine; Mice; Motor Activity; Neurotransmitter Agents; Restraint, Physical; Temperature | 1993 |
Disulfiram therapy in patients abusing cocaine and alcohol.
Topics: Alcoholism; Ambulatory Care; Behavior Therapy; Cocaine; Combined Modality Therapy; Disulfiram; Humans; Substance-Related Disorders | 1993 |
Disulfiram facilitates the development and expression of locomotor sensitization to cocaine in rats.
Topics: Animals; Cocaine; Cocaine-Related Disorders; Disulfiram; Dopamine Uptake Inhibitors; Enzyme Inhibitors; Male; Motor Activity; Rats; Rats, Sprague-Dawley | 2003 |
Norepinephrine signaling through beta-adrenergic receptors is critical for expression of cocaine-induced anxiety.
Topics: Adrenergic beta-Antagonists; Animals; Anxiety; Behavior, Animal; Cocaine; Disease Models, Animal; Disulfiram; Dopamine beta-Hydroxylase; Dose-Response Relationship, Drug; Enzyme Inhibitors; Female; Male; Maze Learning; Mice; Mice, Knockout; Norepinephrine; Propranolol; Receptors, Adrenergic, beta; Signal Transduction | 2008 |
Effects of disulfiram and dopamine beta-hydroxylase knockout on cocaine-induced seizures.
Topics: Alcohol Deterrents; Animals; Cocaine; Disulfiram; Dopamine beta-Hydroxylase; Drug Synergism; Enzyme Inhibitors; Female; Imidazoles; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Seizures; Thiones | 2008 |
Pronounced paranoia as a result of cocaine-disulfiram interaction: case report and mode of action.
Topics: Administration, Intranasal; Adult; Alcohol Deterrents; Alcoholism; Behavior Therapy; Cocaine; Cocaine-Related Disorders; Disulfiram; Dose-Response Relationship, Drug; Drug Interactions; Humans; Male; Paranoid Disorders; Recurrence | 2009 |
Disulfiram attenuates drug-primed reinstatement of cocaine seeking via inhibition of dopamine β-hydroxylase.
Topics: Alcohol Deterrents; Animals; Brain; Cocaine; Conditioning, Operant; Disulfiram; Dopamine; Dopamine beta-Hydroxylase; Drug Interactions; Extinction, Psychological; Food; Imidazoles; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Self Administration; Thiones | 2010 |
Disulfiram stimulates dopamine release from noradrenergic terminals and potentiates cocaine-induced dopamine release in the prefrontal cortex.
Topics: Animals; Brain; Cocaine; Cocaine-Related Disorders; Disulfiram; Dopamine; Dopamine beta-Hydroxylase; Enzyme Inhibitors; Male; Microdialysis; Norepinephrine; Prefrontal Cortex; Rats; Rats, Sprague-Dawley | 2012 |
Chronic inhibition of dopamine β-hydroxylase facilitates behavioral responses to cocaine in mice.
Topics: Animals; Cocaine; Disulfiram; Dopamine beta-Hydroxylase; Female; Imidazoles; Locomotion; Male; Mice; Mice, Knockout; Thiones | 2012 |
Dopamine β-hydroxylase inhibitors enhance the discriminative stimulus effects of cocaine in rats.
Topics: Adrenergic Uptake Inhibitors; Animals; Cocaine; Conditioning, Operant; Discrimination Learning; Discrimination, Psychological; Disulfiram; Dopamine beta-Hydroxylase; Dopamine Uptake Inhibitors; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Imidazoles; Male; Morpholines; Rats; Rats, Sprague-Dawley; Reboxetine; Thiones | 2013 |
Effects of pharmacologic dopamine β-hydroxylase inhibition on cocaine-induced reinstatement and dopamine neurochemistry in squirrel monkeys.
Topics: Animals; Autonomic Nervous System Diseases; Behavior, Addictive; Cocaine; Conditioning, Operant; Disulfiram; Dopamine; Dopamine beta-Hydroxylase; Enzyme Inhibitors; Extinction, Psychological; Imidazoles; Male; Norepinephrine; Nucleus Accumbens; Rats; Saimiri; Self Administration; Thiones | 2014 |
Elevated dopamine in the medial prefrontal cortex suppresses cocaine seeking via D1 receptor overstimulation.
Topics: Animals; Behavior, Animal; Benzazepines; Cocaine; Disulfiram; Dopamine; Dopamine Agents; Dopamine beta-Hydroxylase; Dopamine Uptake Inhibitors; Drug-Seeking Behavior; Extinction, Psychological; Imidazoles; Levodopa; Male; Microdialysis; Prefrontal Cortex; Rats; Rats, Sprague-Dawley; Receptors, Dopamine D1; Self Administration; Thiones | 2016 |
Limited modulation of the abuse-related behavioral effects of d-methamphetamine by disulfiram.
Topics: Acetaldehyde Dehydrogenase Inhibitors; Amphetamine-Related Disorders; Animals; Behavioral Symptoms; Central Nervous System Stimulants; Cocaine; Discrimination, Psychological; Disease Models, Animal; Disulfiram; Dose-Response Relationship, Drug; Female; Macaca mulatta; Male; Methamphetamine; Reinforcement, Psychology; Treatment Outcome | 2018 |
Within-treatment frequency of use versus abstinence as a predictor of longitudinal post-treatment follow-up assessments of drug use.
Topics: Adult; Cocaine; Cocaine-Related Disorders; Cognitive Behavioral Therapy; Disulfiram; Female; Follow-Up Studies; Humans; Longitudinal Studies; Male; Outcome Assessment, Health Care; Psychotherapy; Psychotherapy, Psychodynamic; Randomized Controlled Trials as Topic; Treatment Outcome | 2020 |