disulfiram and cimetidine

disulfiram has been researched along with cimetidine in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19904 (17.39)18.7374
1990's1 (4.35)18.2507
2000's7 (30.43)29.6817
2010's11 (47.83)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Dansette, PM; Fontana, E; Poli, SM1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Austin, CP; Fidock, DA; Hayton, K; Huang, R; Inglese, J; Jiang, H; Johnson, RL; Su, XZ; Wellems, TE; Wichterman, J; Yuan, J1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Campillo, NE; Guerra, A; Páez, JA1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Almdal, TP; Bjerrum, K; Dalhoff, K; Keiding, S; Lund, J; Mengel, H1
Døssing, M; Loft, S; Pilsgaard, H; Poulsen, E; Sonne, J1
Abernethy, DR; Greenblatt, DJ; Ochs, HR; Shader, RI1
Richelson, E1
Havey, RJ1
Hazai, E; Monostory, K; Vereczkey, L1
Bond, GR; Goetz, RJ; Lindsell, CJ; Otten, EJ; Sztajnkrycer, MD1
Collins, J; Fujita, M; Hong, J; Innis, RB; Liow, JS; Pike, VW; Ryu, YH; Sangare, J; Tipre, D; Zoghbi, S1
Beike, J; Bender, K; Jübner, M; Käferstein, H; Lenz, D; Rothschild, MA; Wintermeyer, A1

Reviews

4 review(s) available for disulfiram and cimetidine

ArticleYear
Cytochrome p450 enzymes mechanism based inhibitors: common sub-structures and reactivity.
    Current drug metabolism, 2005, Volume: 6, Issue:5

    Topics: Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Isoenzymes; Structure-Activity Relationship; Terminology as Topic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Alcohol and the elderly. Psychotropics and the elderly: interactions to watch for.
    Geriatrics, 1984, Volume: 39, Issue:12

    Topics: Adult; Age Factors; Aged; Antacids; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Barbiturates; Benzodiazepines; Cimetidine; Disulfiram; Drug Interactions; Ethanol; Half-Life; Humans; Middle Aged; Norepinephrine; Psychotropic Drugs

1984
Over-the-counter and iatrogenically induced psychoses: a review of the literature.
    The Journal of the American Osteopathic Association, 1984, Volume: 83, Issue:6

    Topics: Anti-Arrhythmia Agents; Antihypertensive Agents; Appetite Depressants; Aspirin; Cimetidine; Disulfiram; Drug-Related Side Effects and Adverse Reactions; Humans; Illicit Drugs; Nonprescription Drugs; Parasympatholytics; Psychoses, Substance-Induced; Quinacrine

1984

Other Studies

19 other study(ies) available for disulfiram and cimetidine

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Genetic mapping of targets mediating differential chemical phenotypes in Plasmodium falciparum.
    Nature chemical biology, 2009, Volume: 5, Issue:10

    Topics: Animals; Antimalarials; ATP Binding Cassette Transporter, Subfamily B, Member 1; Chromosome Mapping; Crosses, Genetic; Dihydroergotamine; Drug Design; Drug Resistance; Humans; Inhibitory Concentration 50; Mutation; Plasmodium falciparum; Quantitative Trait Loci; Transfection

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors.
    European journal of medicinal chemistry, 2010, Volume: 45, Issue:3

    Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Pharmacokinetics of paroxetine in patients with cirrhosis.
    European journal of clinical pharmacology, 1991, Volume: 41, Issue:4

    Topics: Adult; Aged; Cimetidine; Disulfiram; Drug Interactions; Female; Half-Life; Humans; Liver Cirrhosis, Alcoholic; Liver Function Tests; Male; Middle Aged; Paroxetine; Piperidines; Serotonin Antagonists

1991
Inhibition of antipyrine elimination by disulfiram and cimetidine: the effect of concomitant administration.
    British journal of clinical pharmacology, 1986, Volume: 21, Issue:1

    Topics: Adult; Antipyrine; Cimetidine; Depression, Chemical; Disulfiram; Drug Interactions; Female; Humans; Liver; Male; Time Factors

1986
Benzodiazepine drug-drug interactions commonly occurring in clinical practice.
    Current medical research and opinion, 1984, Volume: 8 Suppl 4

    Topics: Anti-Anxiety Agents; Benzodiazepines; Cimetidine; Contraceptives, Oral; Disulfiram; Drug Interactions; Enzyme Induction; Ethanol; Humans; Isoniazid; Kinetics; Liver; Mixed Function Oxygenases; Propranolol

1984
Reduction of toxic metabolite formation of acetaminophen.
    Biochemical and biophysical research communications, 2002, Mar-08, Volume: 291, Issue:4

    Topics: Acetaminophen; Analgesics, Non-Narcotic; Benzoquinones; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Disulfiram; Ditiocarb; Enzyme Inhibitors; Fomepizole; Humans; Imines; Microsomes, Liver; Pyrazoles

2002
Mitigation of pennyroyal oil hepatotoxicity in the mouse.
    Academic emergency medicine : official journal of the Society for Academic Emergency Medicine, 2003, Volume: 10, Issue:10

    Topics: Animals; Case-Control Studies; Cimetidine; Cyclohexane Monoterpenes; Cyclohexanones; Disease Models, Animal; Disulfiram; Enzyme Inhibitors; Female; Hedeoma; Liver Diseases; Mentha pulegium; Mice; Mice, Inbred BALB C; Monoterpenes; Oils, Volatile

2003
Disulfiram inhibits defluorination of (18)F-FCWAY, reduces bone radioactivity, and enhances visualization of radioligand binding to serotonin 5-HT1A receptors in human brain.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 2007, Volume: 48, Issue:7

    Topics: Adult; Animals; Brain; Cimetidine; Cyclohexanes; Cytochrome P-450 CYP2E1; Cytochrome P-450 CYP2E1 Inhibitors; Disulfiram; Female; Fluorine Radioisotopes; Haplorhini; Humans; Ligands; Male; Middle Aged; Piperazines; Positron-Emission Tomography; Radiopharmaceuticals; Receptor, Serotonin, 5-HT1A; Skull

2007
Inhibition of 1,4-butanediol metabolism in human liver in vitro.
    Naunyn-Schmiedeberg's archives of pharmacology, 2011, Volume: 383, Issue:6

    Topics: Adult; Aged; Antidotes; Butylene Glycols; Cimetidine; Disulfiram; Drug Interactions; Ethanol; Female; Fomepizole; Gas Chromatography-Mass Spectrometry; Humans; Hydroxybutyrates; In Vitro Techniques; Liver; Male; Middle Aged; Pyrazoles

2011