disulfiram and allopurinol

disulfiram has been researched along with allopurinol in 26 studies

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-199014 (53.85)18.7374
1990's0 (0.00)18.2507
2000's4 (15.38)29.6817
2010's8 (30.77)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Bellows, DS; Clarke, ID; Diamandis, P; Dirks, PB; Graham, J; Jamieson, LG; Ling, EK; Sacher, AG; Tyers, M; Ward, RJ; Wildenhain, J1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Fang, H; Liu, Z; Shi, Q; Tong, W; Vijay, V1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL1
Fried, R1
Christensen, LK; Hansen, JM1
Della Corte, E; Stirpe, F1
Schedifka, R1
Gibbs, DA; Watts, RW3
Glogner, P1
Holck, HG; Lish, PM; Malone, MH; Sjogren, DW; Westerfeld, WW1
Berger, R; Broyer, M1
Goodhue, WW1
Blake, DA; Cascorbi, HF; Meyer, FJ; Rozman, RS1
Evets, MA; Korablev, MV; Kurbat, NM1
RICHERT, DA; VANDERLINDE, R; WESTERFELD, WW1
Beedham, C; Panoutsopoulos, GI1

Reviews

4 review(s) available for disulfiram and allopurinol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Drug interactions with oral sulphonylurea hypoglycaemic drugs.
    Drugs, 1977, Volume: 13, Issue:1

    Topics: Allopurinol; Analgesics; Anticoagulants; Chloramphenicol; Chlorpropamide; Disulfiram; Drug Interactions; Ethanol; Glyburide; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Kinetics; Monoamine Oxidase Inhibitors; Novobiocin; Phenylbutazone; Phenytoin; Probenecid; Propranolol; Rifampin; Sulfonamides; Sulfonylurea Compounds; Tolbutamide

1977
[Further facts about the effects of disulfiram].
    Zeitschrift fur arztliche Fortbildung, 1970, Feb-01, Volume: 64, Issue:3

    Topics: Acetaldehyde; Alcohol Oxidoreductases; Alcoholism; Animals; Disulfiram; Drug Tolerance; Humans; Oxygen Consumption; Rabbits; Rats; Succinate Dehydrogenase; Xanthine Oxidase

1970
[Molecular basis of the antialcoholic mechanism of action of teturam (review)].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1981, Volume: 81, Issue:2

    Topics: Acetaldehyde; Alcohol Oxidoreductases; Aldehyde Oxidoreductases; Animals; Biotransformation; Catecholamines; Cats; Disulfiram; Ditiocarb; Dogs; Dopamine beta-Hydroxylase; Ethanol; Humans; In Vitro Techniques; Mice; Rabbits; Rats; Serotonin; Tyrosine 3-Monooxygenase; Xanthine Oxidase

1981

Other Studies

22 other study(ies) available for disulfiram and allopurinol

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutical Preparations; Sensitivity and Specificity; Stem Cells

2007
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors.
    Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21

    Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
FDA-approved drug labeling for the study of drug-induced liver injury.
    Drug discovery today, 2011, Volume: 16, Issue:15-16

    Topics: Animals; Benchmarking; Biomarkers, Pharmacological; Chemical and Drug Induced Liver Injury; Drug Design; Drug Labeling; Drug-Related Side Effects and Adverse Reactions; Humans; Pharmaceutical Preparations; Reproducibility of Results; United States; United States Food and Drug Administration

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
    PloS one, 2016, Volume: 11, Issue:10

    Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat

2016
Enzymatic oxidation of diethyldithiocarbamate by xanthine oxidase and its colorimetric assay.
    Annals of the New York Academy of Sciences, 1976, Volume: 273

    Topics: Colorimetry; Disulfiram; Ditiocarb; Methods; Nitroblue Tetrazolium; Oxidation-Reduction; Thiocarbamates; Xanthine Oxidase

1976
The regulation of rat liver xanthine oxidase. Involvement of thiol groups in the conversion of the enzyme activity from dehydrogenase (type D) into oxidase (type O) and purification of the enzyme.
    The Biochemical journal, 1972, Volume: 126, Issue:3

    Topics: Animals; Chickens; Columbidae; Copper; Disulfiram; Dithiothreitol; Ethylmaleimide; Female; Hydroxymercuribenzoates; In Vitro Techniques; Intestines; Kidney; Liver; Lung; Male; Myocardium; NAD; Oxidoreductases; Pancreas; Rats; Spleen; Sulfates; Sulfhydryl Reagents; Xanthine Oxidase

1972
Biochemical studies on the treatment of primary hyperoxaluria.
    Archives of disease in childhood, 1967, Volume: 42, Issue:225

    Topics: Adolescent; Allopurinol; Child; Dietary Proteins; Disulfiram; Enzyme Inhibitors; Female; Folic Acid; Humans; Male; Metabolic Diseases; Oxalates; Pyridoxine; Vitamin K

1967
The metabolism of tolbutamide and cyclamate.
    Humangenetik, 1970, Volume: 9, Issue:3

    Topics: Allopurinol; Amines; Animals; Biotransformation; Cyclohexanes; Disulfiram; Female; Humans; Male; Microsomes, Liver; Rabbits; Sweetening Agents; Tolbutamide

1970
Effects of disulfiram on growth, longevity, and reproduction of the albino rat.
    Journal of pharmaceutical sciences, 1970, Volume: 59, Issue:9

    Topics: Age Factors; Animals; Ascorbic Acid; Blood Cell Count; Body Weight; Diet; Disulfiram; Female; Growth; Liver; Longevity; Male; Molybdenum; Oxygen Consumption; Rats; Reproduction; Sex Factors; Xanthine Oxidase

1970
[Oxalosis].
    La Presse medicale, 1968, Dec-21, Volume: 76, Issue:50

    Topics: Acidosis, Renal Tubular; Alcohol Oxidoreductases; Allopurinol; Biopsy; Blood Urea Nitrogen; Calcium Metabolism Disorders; Disulfiram; Enzyme Repression; Glyoxylates; Humans; Kidney; Kidney Calculi; Kidney Failure, Chronic; Leukocytes; Nephrocalcinosis; Oxalates; Pyridoxine

1968
Disulfiram-metronidazole (well identified) toxicity.
    The New England journal of medicine, 1969, Jun-26, Volume: 280, Issue:26

    Topics: Disulfiram; Humans; Metronidazole; Psychoses, Substance-Induced; Xanthine Oxidase

1969
Animal toxicity of 2,2,2-trifluoroethanol.
    Toxicology and applied pharmacology, 1969, Volume: 15, Issue:1

    Topics: Acetates; Alcohol Oxidoreductases; Alcohols; Allopurinol; Animals; Carbon Isotopes; Disulfiram; Dogs; Ethanol; Fluoroacetates; Glucuronates; Hydrocarbons, Halogenated; In Vitro Techniques; Male; Mice; Triazoles; Yeasts

1969
An investigation of the possible role of xanthine oxidase in the oxidation of glyoxylate to oxalate.
    Clinical science, 1966, Volume: 31, Issue:2

    Topics: Adult; Aldehydes; Animals; Disulfiram; Enzymes; Glyoxylates; Gout; Humans; In Vitro Techniques; Kinetics; Liver; Male; Middle Aged; Milk; Oxalates; Rats; Xanthine Oxidase

1966
Oxalate formation from glyoxylate in primary hyperoxaluria: studies on liver tissue.
    Clinical science, 1967, Volume: 32, Issue:3

    Topics: Allopurinol; Catalysis; Child; Culture Techniques; Disulfiram; Enzyme Induction; Female; Humans; Liver; Oxalates; Pteridines; Xanthine Oxidase

1967
The composition of rat liver xanthine oxidase and its inhibition by antabuse.
    The Journal of biological chemistry, 1950, Volume: 186, Issue:1

    Topics: Coloring Agents; Disulfiram; Liver; Oxidoreductases; Peroxidase; Peroxidases; Xanthine Oxidase

1950
Metabolism of isovanillin by aldehyde oxidase, xanthine oxidase, aldehyde dehydrogenase and liver slices.
    Pharmacology, 2005, Volume: 73, Issue:4

    Topics: Aldehyde Dehydrogenase; Aldehyde Oxidase; Allopurinol; Animals; Benzaldehydes; Cryopreservation; Disulfiram; Guinea Pigs; Hydroxybenzoates; Liver; Time Factors; Vanillic Acid; Xanthine Oxidase

2005