disulfiram and acetaminophen

disulfiram has been researched along with acetaminophen in 18 studies

Research

Studies (18)

Timeframe	Studies, this research(%)	All Research%
pre-1990	2 (11.11)	18.7374
1990's	2 (11.11)	18.2507
2000's	6 (33.33)	29.6817
2010's	8 (44.44)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
González-Díaz, H; Orallo, F; Quezada, E; Santana, L; Uriarte, E; Viña, D; Yáñez, M	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Campillo, NE; Guerra, A; Páez, JA	1
Ekins, S; Williams, AJ; Xu, JJ	1
Bellera, CL; Bruno-Blanch, LE; Castro, EA; Duchowicz, PR; Goodarzi, M; Ortiz, EV; Pesce, G; Talevi, A	1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Jørgensen, L; Poulsen, HE; Ranek, L	1
Jørgensen, L; Poulsen, HE; Thomsen, P	2
Jørgensen, G	1
Hazai, E; Monostory, K; Vereczkey, L	1
Hansen, BA; Larsen, FS; Schmidt, LE; Wang, LP	1
Barkan, D; Deharo, E; Ginsburg, H; Golenser, J; Krugliak, M	1
Ceña, V; Posadas, I; Prieto-Lloret, J; Santos, P; Vellecco, V	1

Reviews

1 review(s) available for disulfiram and acetaminophen

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Trials

1 trial(s) available for disulfiram and acetaminophen

Article	Year
Systemic hemodynamic effects of treatment with the molecular adsorbents recirculating system in patients with hyperacute liver failure: a prospective controlled trial. Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2003, Volume: 9, Issue:3 Topics: Acetaminophen; Adult; Alcohol Deterrents; Analgesics, Non-Narcotic; Blood Pressure; Chemical and Drug Induced Liver Injury; Disulfiram; Female; Heart Rate; Hepatitis B; Humans; Liver Failure, Acute; Male; Middle Aged; Oxygen; Prospective Studies; Pulmonary Wedge Pressure; Sorption Detoxification; Temperature; Treatment Outcome	2003

Article

Year

Systemic hemodynamic effects of treatment with the molecular adsorbents recirculating system in patients with hyperacute liver failure: a prospective controlled trial.

Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society, 2003, Volume: 9, Issue:3

Topics: Acetaminophen; Adult; Alcohol Deterrents; Analgesics, Non-Narcotic; Blood Pressure; Chemical and Drug Induced Liver Injury; Disulfiram; Female; Heart Rate; Hepatitis B; Humans; Liver Failure, Acute; Male; Middle Aged; Oxygen; Prospective Studies; Pulmonary Wedge Pressure; Sorption Detoxification; Temperature; Treatment Outcome

2003

Other Studies

16 other study(ies) available for disulfiram and acetaminophen

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Quantitative structure-activity relationship and complex network approach to monoamine oxidase A and B inhibitors. Journal of medicinal chemistry, 2008, Nov-13, Volume: 51, Issue:21 Topics: Computational Biology; Drug Design; Humans; Isoenzymes; Molecular Structure; Monoamine Oxidase; Monoamine Oxidase Inhibitors; Quantitative Structure-Activity Relationship	2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Neural computational prediction of oral drug absorption based on CODES 2D descriptors. European journal of medicinal chemistry, 2010, Volume: 45, Issue:3 Topics: Administration, Oral; Humans; Models, Chemical; Neural Networks, Computer; Permeability; Quantitative Structure-Activity Relationship; Technology, Pharmaceutical	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
Prediction of drug intestinal absorption by new linear and non-linear QSPR. European journal of medicinal chemistry, 2011, Volume: 46, Issue:1 Topics: Humans; Intestinal Absorption; Linear Models; Molecular Conformation; Nonlinear Dynamics; Permeability; Pharmaceutical Preparations; Probability; Quantitative Structure-Activity Relationship; Thermodynamics	2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds. Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10 Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding	2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development. Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests	2013
The influence of disulfiram on acetaminophen metabolism in man. Xenobiotica; the fate of foreign compounds in biological systems, 1991, Volume: 21, Issue:2 Topics: Acetaminophen; Adult; Aged; Alcoholism; Disulfiram; Drug Interactions; Female; Humans; Liver Cirrhosis, Alcoholic; Male; Metabolic Clearance Rate; Middle Aged	1991
Disulfiram prevents acetaminophen hepatotoxicity in rats. Pharmacology & toxicology, 1988, Volume: 62, Issue:5 Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Disulfiram; Female; Rats; Rats, Inbred Strains	1988
Prevention of acetaminophen hepatotoxicity by disulfiram. Pharmacology & therapeutics, 1987, Volume: 33, Issue:1 Topics: Acetaminophen; Animals; Chemical and Drug Induced Liver Injury; Disulfiram; Female; Liver; Liver Function Tests; Rats; Rats, Inbred Strains	1987
[Effects of drugs on the liver. A review illustrated with 3 clinical cases]. Ugeskrift for laeger, 1994, Jan-10, Volume: 156, Issue:2 Topics: Acetaminophen; Adult; Aged; Androgens; Chemical and Drug Induced Liver Injury; Denmark; Disulfiram; Drug-Related Side Effects and Adverse Reactions; Female; Halothane; Humans; Male; Methotrexate; Middle Aged; Sulfamethizole	1994
Reduction of toxic metabolite formation of acetaminophen. Biochemical and biophysical research communications, 2002, Mar-08, Volume: 291, Issue:4 Topics: Acetaminophen; Analgesics, Non-Narcotic; Benzoquinones; Cimetidine; Cytochrome P-450 Enzyme Inhibitors; Disulfiram; Ditiocarb; Enzyme Inhibitors; Fomepizole; Humans; Imines; Microsomes, Liver; Pyrazoles	2002
Potentiation of the antimalarial action of chloroquine in rodent malaria by drugs known to reduce cellular glutathione levels. Biochemical pharmacology, 2003, Sep-01, Volume: 66, Issue:5 Topics: Acetaminophen; Acetylcysteine; Aminoquinolines; Animals; Antimalarials; Chloroquine; Disulfiram; Drug Synergism; Glutathione; Indomethacin; Malaria; Mice; Plasmodium berghei; Plasmodium falciparum	2003
Acetaminophen potentiates staurosporine-induced death in a human neuroblastoma cell line. British journal of pharmacology, 2007, Volume: 150, Issue:5 Topics: Acetaminophen; Acetylcysteine; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Line, Tumor; Cell Survival; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochromes c; Dinoprostone; Disulfiram; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Activation; Free Radical Scavengers; Glutathione; Humans; Metalloporphyrins; Neuroblastoma; Prostaglandin-Endoperoxide Synthases; Staurosporine; Time Factors	2007